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Items: 17


Two distinct conformations of factor H regulate discrete complement-binding functions in the fluid phase and at cell surfaces.

Osborne AJ, Nan R, Miller A, Bhatt JS, Gor J, Perkins SJ.

J Biol Chem. 2018 Nov 2;293(44):17166-17187. doi: 10.1074/jbc.RA118.004767. Epub 2018 Sep 14.


Statistical Validation of Rare Complement Variants Provides Insights into the Molecular Basis of Atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy.

Osborne AJ, Breno M, Borsa NG, Bu F, Frémeaux-Bacchi V, Gale DP, van den Heuvel LP, Kavanagh D, Noris M, Pinto S, Rallapalli PM, Remuzzi G, Rodríguez de Cordoba S, Ruiz A, Smith RJH, Vieira-Martins P, Volokhina E, Wilson V, Goodship THJ, Perkins SJ.

J Immunol. 2018 Apr 1;200(7):2464-2478. doi: 10.4049/jimmunol.1701695. Epub 2018 Mar 2.


A 'phenotypic hangover': the predictive adaptive response and multigenerational effects of altered nutrition on the transcriptome of Drosophila melanogaster.

Osborne AJ, Dearden PK.

Environ Epigenet. 2017 Dec 5;3(4):dvx019. doi: 10.1093/eep/dvx019. eCollection 2017 Oct.


Complete Genome Sequences of Two Geographically Distinct Legionella micdadei Clinical Isolates.

Osborne AJ, Jose BR, Perry J, Smeele Z, Aitken J, Gardner PP, Slow S.

Genome Announc. 2017 Jun 1;5(22). pii: e00436-17. doi: 10.1128/genomeA.00436-17.


Genetic Evidence of a Population Bottleneck and Inbreeding in the Endangered New Zealand Sea Lion, Phocarctos hookeri.

Osborne AJ, Negro SS, Chilvers BL, Robertson BC, Kennedy MA, Gemmell NJ.

J Hered. 2016 Sep;107(5):392-402. doi: 10.1093/jhered/esw015. Epub 2016 Mar 19.


Specimen Referral Network to Rapidly Scale-Up CD4 Testing: The Hub and Spoke Model for Haiti.

Louis FJ, Osborne AJ, Elias VJ, Buteau J, Boncy J, Elong A, Dismer A, Sasi V, Domercant JW, Lauture D, Balajee SA, Marston BJ.

J AIDS Clin Res. 2015;6(8). pii: 1000488. Epub 2015 Jun 26.


Examining the role of components of Slc11a1 (Nramp1) in the susceptibility of New Zealand sea lions (Phocarctos hookeri) to disease.

Osborne AJ, Pearson J, Chilvers BL, Kennedy MA, Gemmell NJ.

PLoS One. 2015 Apr 14;10(4):e0122703. doi: 10.1371/journal.pone.0122703. eCollection 2015.


Heterozygote advantage at MHC DRB may influence response to infectious disease epizootics.

Osborne AJ, Pearson J, Negro SS, Chilvers BL, Kennedy MA, Gemmell NJ.

Mol Ecol. 2015 Apr;24(7):1419-32. doi: 10.1111/mec.13128. Epub 2015 Mar 19.


New functional and structural insights from updated mutational databases for complement factor H, Factor I, membrane cofactor protein and C3.

Rodriguez E, Rallapalli PM, Osborne AJ, Perkins SJ.

Biosci Rep. 2014 Oct 22;34(5). pii: e00146. doi: 10.1042/BSR20140117.


An evaluation of operative self-assessment by UK postgraduate trainees.

Osborne AJ, Hawkins SC, Pournaras DJ, Chandratilake M, Welbourn R.

Med Teach. 2014 Jan;36(1):32-7. doi: 10.3109/0142159X.2013.836268. Epub 2013 Oct 23.


Extensive variation at MHC DRB in the New Zealand sea lion (Phocarctos hookeri) provides evidence for balancing selection.

Osborne AJ, Zavodna M, Chilvers BL, Robertson BC, Negro SS, Kennedy MA, Gemmell NJ.

Heredity (Edinb). 2013 Jul;111(1):44-56. doi: 10.1038/hdy.2013.18. Epub 2013 Apr 10.


Single incision laparoscopic adjustable gastric band: technique, feasibility, safety and learning curve.

Osborne AJ, Clancy R, Clark GW, Wong C.

Ann R Coll Surg Engl. 2013 Mar;95(2):131-3. doi: 10.1308/003588413X13511609954978.


Comparison of single-incision laparoscopic high anterior resection with standard laparoscopic high anterior resection.

Osborne AJ, Lim J, Gash KJ, Chaudhary B, Dixon AR.

Colorectal Dis. 2013 Mar;15(3):329-33. doi: 10.1111/j.1463-1318.2012.03178.x.


Development of a predicted physical map of microsatellite locus positions for pinnipeds, with wider applicability to the Carnivora.

Osborne AJ, Brauning R, Schultz JK, Kennedy MA, Slate J, Gemmell NJ.

Mol Ecol Resour. 2011 May;11(3):503-13. doi: 10.1111/j.1755-0998.2010.02962.x. Epub 2010 Dec 28.


Gastrointestinal tract colonization with vancomycin-resistant Enterococcus faecium in an animal model.

Whitman MS, Pitsakis PG, DeJesus E, Osborne AJ, Levison ME, Johnson CC.

Antimicrob Agents Chemother. 1996 Jun;40(6):1526-30.


Antibiotic treatment of experimental endocarditis due to vancomycin- and ampicillin-resistant Enterococcus faecium.

Whitman MS, Pitsakis PG, Zausner A, Livornese LL, Osborne AJ, Johnson CC, Levison ME.

Antimicrob Agents Chemother. 1993 Oct;37(10):2069-73.


The effects of oral ginseng administration on the activities and isoenzyme profiles of murine lactate dehydrogenases.

Harper N, Osborne AJ, Makov VE, Bittles AH.

Biochem Pharmacol. 1984 May 1;33(9):1571-3. No abstract available.


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