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Items: 43

1.

3,5-Disubstituted-indole-7-carboxamides as IKK╬▓ Inhibitors: Optimization of Oral Activity via the C3 Substituent.

Kerns JK, Busch-Petersen J, Fu W, Boehm JC, Nie H, Muratore M, Bullion A, Lin G, Li H, Davis R, Lin X, Lakdawala AS, Cousins R, Field R, Payne J, Miller DD, Bamborough P, Christopher JA, Baldwin I, Osborn RR, Yonchuk J, Webb E, Rumsey WL.

ACS Med Chem Lett. 2018 Oct 30;9(12):1164-1169. doi: 10.1021/acsmedchemlett.8b00291. eCollection 2018 Dec 13.

PMID:
30613320
2.

Pediatric Chief Residents' Experiences as Inpatient Attending Physicians.

Banker SL, Berkwitt A, Osborn RR.

Acad Pediatr. 2019 May - Jun;19(4):404-409. doi: 10.1016/j.acap.2018.11.010. Epub 2018 Nov 22.

PMID:
30472279
3.

Adherence to AAP Healthy Newborn Discharge Criteria in a Tertiary Care Children's Hospital.

Arora NS, Danicek AM, Osborn RR, Fried SQ, Negris OR, Lychuk K, Mychaliska KP, Skoczylas MS, Monroe KK.

Hosp Pediatr. 2018 Nov;8(11):665-671. doi: 10.1542/hpeds.2018-0061. Epub 2018 Oct 2.

PMID:
30279199
4.

A Novel Approach to Assessing Infants With Neonatal Abstinence Syndrome.

Grossman MR, Lipshaw MJ, Osborn RR, Berkwitt AK.

Hosp Pediatr. 2018 Jan;8(1):1-6. doi: 10.1542/hpeds.2017-0128.

5.

Buprenorphine for the Neonatal Abstinence Syndrome.

Grossman MR, Berkwitt AK, Osborn RR.

N Engl J Med. 2017 Sep 7;377(10):996-7. doi: 10.1056/NEJMc1709121. No abstract available.

PMID:
28880503
6.

An Initiative to Improve the Quality of Care of Infants With Neonatal Abstinence Syndrome.

Grossman MR, Berkwitt AK, Osborn RR, Xu Y, Esserman DA, Shapiro ED, Bizzarro MJ.

Pediatrics. 2017 Jun;139(6). pii: e20163360. doi: 10.1542/peds.2016-3360. Epub 2017 May 18.

7.

Neonatal Abstinence Syndrome: Time for a Reappraisal.

Grossman MR, Osborn RR, Berkwitt AK.

Hosp Pediatr. 2017 Feb;7(2):115-116. doi: 10.1542/hpeds.2016-0119. No abstract available.

8.

Effects of airborne toxicants on pulmonary function and mitochondrial DNA damage in rodent lungs.

Rumsey WL, Bolognese B, Davis AB, Flamberg PL, Foley JP, Katchur SR, Kotzer CJ, Osborn RR, Podolin PL.

Mutagenesis. 2017 May 1;32(3):343-353. doi: 10.1093/mutage/gew063.

PMID:
27993944
9.

A piece of my mind. The mask.

Osborn RR.

JAMA. 2014 Jan 15;311(3):245-6. doi: 10.1001/jama.2013.284778. No abstract available.

PMID:
24430317
10.

Identification of a selective nonpeptide antagonist of the anaphylatoxin C3a receptor that demonstrates antiinflammatory activity in animal models.

Ames RS, Lee D, Foley JJ, Jurewicz AJ, Tornetta MA, Bautsch W, Settmacher B, Klos A, Erhard KF, Cousins RD, Sulpizio AC, Hieble JP, McCafferty G, Ward KW, Adams JL, Bondinell WE, Underwood DC, Osborn RR, Badger AM, Sarau HM.

J Immunol. 2001 May 15;166(10):6341-8.

11.

SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung.

Underwood DC, Osborn RR, Bochnowicz S, Webb EF, Rieman DJ, Lee JC, Romanic AM, Adams JL, Hay DW, Griswold DE.

Am J Physiol Lung Cell Mol Physiol. 2000 Nov;279(5):L895-902.

12.

Differences in time-related cardiopulmonary responses to hypoxia in three rat strains.

Bochnowicz S, Osborn RR, Luttmann MA, Louden C, Hart T, Hay DW, Underwood DC.

Clin Exp Hypertens. 2000 Jul;22(5):471-92.

PMID:
10937839
13.

SB 239063, a potent p38 MAP kinase inhibitor, reduces inflammatory cytokine production, airways eosinophil infiltration, and persistence.

Underwood DC, Osborn RR, Kotzer CJ, Adams JL, Lee JC, Webb EF, Carpenter DC, Bochnowicz S, Thomas HC, Hay DW, Griswold DE.

J Pharmacol Exp Ther. 2000 Apr;293(1):281-8.

PMID:
10734180
14.

Effect of SB 217242 on hypoxia-induced cardiopulmonary changes in the high altitude-sensitive rat.

Underwood DC, Bochnowicz S, Osborn RR, Luttmann MA, Louden CS, Hart TK, Elliott JD, Hay DW.

Pulm Pharmacol Ther. 1999;12(1):13-26.

PMID:
10208832
15.

Antiasthmatic activity of the second-generation phosphodiesterase 4 (PDE4) inhibitor SB 207499 (Ariflo) in the guinea pig.

Underwood DC, Bochnowicz S, Osborn RR, Kotzer CJ, Luttmann MA, Hay DW, Gorycki PD, Christensen SB, Torphy TJ.

J Pharmacol Exp Ther. 1998 Dec;287(3):988-95.

PMID:
9864284
16.

Food restriction-mediated adrenal influences on antigen-induced bronchoconstriction and airway eosinophil influx in the guinea pig.

Underwood DC, Matthews JK, Osborn RR, Hay DW.

Int Arch Allergy Immunol. 1998 Sep;117(1):52-9.

PMID:
9751848
17.

Communicating with elders: effects of speaker-listener distance.

Erber NP, Holland J, Osborn RR.

Br J Audiol. 1998 Jun;32(3):135-8.

PMID:
9710332
18.

Chronic hypoxia-induced cardiopulmonary changes in three rat strains: inhibition by the endothelin receptor antagonist SB 217242.

Underwood DC, Bochnowicz S, Osborn RR, Louden CS, Hart TK, Ohlstein EH, Hay DW.

J Cardiovasc Pharmacol. 1998;31 Suppl 1:S453-5.

PMID:
9595510
19.

1,4-Cyclohexanecarboxylates: potent and selective inhibitors of phosophodiesterase 4 for the treatment of asthma.

Christensen SB, Guider A, Forster CJ, Gleason JG, Bender PE, Karpinski JM, DeWolf WE Jr, Barnette MS, Underwood DC, Griswold DE, Cieslinski LB, Burman M, Bochnowicz S, Osborn RR, Manning CD, Grous M, Hillegas LM, Bartus JO, Ryan MD, Eggleston DS, Haltiwanger RC, Torphy TJ.

J Med Chem. 1998 Mar 12;41(6):821-35.

PMID:
9526558
20.
21.

Hypoxia-induced pulmonary hypertension in an optimized environment for the guineapig.

Bochnowicz S, Osborn RR, Hay DW, Underwood DC.

Lab Anim. 1997 Oct;31(4):347-56.

PMID:
9350706
22.

The influence of endogenous catecholamines on the inhibitory effects of rolipram against early- and late-phase response to antigen in the guinea pig.

Underwood DC, Matthews JK, Osborn RR, Bochnowicz S, Torphy TJ.

J Pharmacol Exp Ther. 1997 Jan;280(1):210-9.

PMID:
8996198
23.
24.

Catecholamine and beta-adrenoceptor influences on airway reactivity to antigen in guinea pigs.

Underwood DC, Matthews JK, Osborn RR, Novak LB, Bochnowicz S, Meunier LD.

Int Arch Allergy Immunol. 1996 Mar;109(3):286-94.

PMID:
8620099
25.

Message from a dinosaur.

Osborn RR.

Radiol Manage. 1996 Mar-Apr;18(2):59-62. No abstract available.

PMID:
10161323
26.

Comparison of phosphodiesterase III, IV and dual III/IV inhibitors on bronchospasm and pulmonary eosinophil influx in guinea pigs.

Underwood DC, Kotzer CJ, Bochnowicz S, Osborn RR, Luttmann MA, Hay DW, Torphy TJ.

J Pharmacol Exp Ther. 1994 Jul;270(1):250-9.

PMID:
8035322
27.

Inhibition of antigen-induced bronchoconstriction and eosinophil infiltration in the guinea pig by the cyclic AMP-specific phosphodiesterase inhibitor, rolipram.

Underwood DC, Osborn RR, Novak LB, Matthews JK, Newsholme SJ, Undem BJ, Hand JM, Torphy TJ.

J Pharmacol Exp Ther. 1993 Jul;266(1):306-13.

PMID:
8392555
28.

Lack of late-phase airway responses in conscious guinea pigs after a variety of antigen challenges.

Underwood DC, Osborn RR, Hand JM.

Agents Actions. 1992 Nov;37(3-4):191-4.

PMID:
1295368
29.
30.

Pharmacologic and pharmacokinetic profile of SK&F S-106203, a potent, orally active peptidoleukotriene receptor antagonist, in guinea-pig.

Hay DW, Muccitelli RM, Vickery-Clark LM, Novak LS, Osborn RR, Gleason JG, Yodis LA, Saverino CM, Eckardt RD, Sarau HM, et al.

Pulm Pharmacol. 1991;4(3):177-89.

PMID:
1668219
31.

International relations: challenge of the future.

Osborn RR.

Radiol Manage. 1989 Summer;11(3):76-7.

PMID:
10316405
32.

The bronchopulmonary pharmacology of SK&F 104353 in anesthetized guinea pigs: demonstration of potent and selective antagonism of responses to peptidoleukotrienes.

Torphy TJ, Newton JF, Wasserman MA, Vickery-Clark L, Osborn RR, Bailey LS, Yodis LA, Underwood DC, Hay DW.

J Pharmacol Exp Ther. 1989 May;249(2):430-7.

PMID:
2542530
33.

Pharmacologic profile of SK&F 104353, a novel, highly potent and selective peptidoleukotriene antagonist.

Wasserman MA, Torphy TJ, Hay DW, Muccitelli RM, Tucker SS, Wilson KA, Osborn RR, Vickery-Clark L, Hall RF, Erhard KF, et al.

Adv Prostaglandin Thromboxane Leukot Res. 1987;17A:532-5. No abstract available.

PMID:
2821765
34.

Radiology survival in a cost-sensitive environment.

Osborn RR.

Radiol Manage. 1986 Jan;8(1):19-21.

PMID:
10300673
35.

Industrial fitness programs: the physician's role.

Sands MJ Jr, Osborn RR, Leach CN Jr, Lachman AS.

Conn Med. 1984 Jan;48(1):1-6. No abstract available.

PMID:
6723280
36.

2-nor-leukotriene analogs: antagonists of the airway and vascular smooth muscle effects of leukotriene C4, D4 and E4.

Gleason JG, Ku TW, McCarthy ME, Weichman BM, Holden D, Osborn RR, Zabko-Potapovich B, Berkowitz B, Wasserman MA.

Biochem Biophys Res Commun. 1983 Dec 28;117(3):732-9.

PMID:
6320814
37.

Antagonism of the pulmonary effects of the peptidoleukotrienes by a leukotriene D4 analog.

Weichman BM, Wasserman MA, Holden DA, Osborn RR, Woodward DF, Ku TW, Gleason JG.

J Pharmacol Exp Ther. 1983 Dec;227(3):700-5.

PMID:
6655563
38.

Effect of inhibition of thromboxane production on the leukotriene D4-mediated bronchoconstriction in the guinea pig.

Muccitelli RM, Osborn RR, Weichman BM.

Prostaglandins. 1983 Aug;26(2):197-206.

PMID:
6689082
39.

In vitro and in vivo mechanisms of leukotriene-mediated bronchoconstriction in the guinea pig.

Weichman BM, Muccitelli RM, Osborn RR, Holden DA, Gleason JG, Wasserman MA.

J Pharmacol Exp Ther. 1982 Jul;222(1):202-8. No abstract available.

PMID:
6283068
40.

American Hospital Radiology Administrators: a decade of progress.

Osborn RR.

Appl Radiol. 1982 Jul-Aug;11(4):27-9.

PMID:
10262043
41.

President's message.

Osborn RR.

Radiol Technol. 1969 Nov;41(3):158. No abstract available.

PMID:
5349867
42.

Green light screens and high speed photographic films. An experiment.

OSBORN RR.

Xray Tech. 1960 Nov;32:249-51. No abstract available.

PMID:
13731380
43.

Improved portable radiographs of the trunk without the use of grids or Bucky.

OSBORN RR.

Xray Tech. 1960 Sep;32:145-7. No abstract available.

PMID:
13731381

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