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Items: 1 to 50 of 154

1.

Lesion of the OVLT markedly attenuates chronic deoxycorticosterone acetate (DOCA) salt hypertension in the rat.

Collister JP, Nahey DB, Hartson R, Wiedmeyer CE, Banek CT, Osborn JW.

Am J Physiol Regul Integr Comp Physiol. 2018 Jun 13. doi: 10.1152/ajpregu.00433.2017. [Epub ahead of print]

PMID:
29897819
2.

Targeted afferent renal denervation reduces arterial pressure but not renal inflammation in established DOCA-salt hypertension in the rat.

Banek CT, Gauthier MM, Baumann DC, Van Helden D, Asirvatham-Jeyaraj N, Panoskaltsis-Mortari A, Fink GD, Osborn JW.

Am J Physiol Regul Integr Comp Physiol. 2018 Jun 1;314(6):R883-R891. doi: 10.1152/ajpregu.00416.2017. Epub 2018 Mar 7.

PMID:
29513561
3.

Role of afferent and efferent renal nerves in the development of AngII-salt hypertension in rats.

Foss JD, Fiege J, Shimizu Y, Collister JP, Mayerhofer T, Wood L, Osborn JW.

Physiol Rep. 2018 Feb;6(3). doi: 10.14814/phy2.13602.

4.

Catheter-Based Renal Nerve Ablation as a Novel Hypertension Therapy: Lost, and Then Found, in Translation.

Osborn JW, Banek CT.

Hypertension. 2018 Mar;71(3):383-388. doi: 10.1161/HYPERTENSIONAHA.117.08928. Epub 2018 Jan 2. Review. No abstract available.

PMID:
29295850
5.

Recording sympathetic nerve activity in conscious humans and other mammals: guidelines and the road to standardization.

Hart EC, Head GA, Carter JR, Wallin BG, May CN, Hamza SM, Hall JE, Charkoudian N, Osborn JW.

Am J Physiol Heart Circ Physiol. 2017 May 1;312(5):H1031-H1051. doi: 10.1152/ajpheart.00703.2016. Epub 2017 Mar 31. Review.

6.

Renal Nerves and Long-Term Control of Arterial Pressure.

Osborn JW, Foss JD.

Compr Physiol. 2017 Mar 16;7(2):263-320. doi: 10.1002/cphy.c150047. Review.

PMID:
28333375
7.

Resting Afferent Renal Nerve Discharge and Renal Inflammation: Elucidating the Role of Afferent and Efferent Renal Nerves in Deoxycorticosterone Acetate Salt Hypertension.

Banek CT, Knuepfer MM, Foss JD, Fiege JK, Asirvatham-Jeyaraj N, Van Helden D, Shimizu Y, Osborn JW.

Hypertension. 2016 Dec;68(6):1415-1423. Epub 2016 Oct 3.

8.

Renal Denervation Normalizes Arterial Pressure With No Effect on Glucose Metabolism or Renal Inflammation in Obese Hypertensive Mice.

Asirvatham-Jeyaraj N, Fiege JK, Han R, Foss J, Banek CT, Burbach BJ, Razzoli M, Bartolomucci A, Shimizu Y, Panoskaltsis-Mortari A, Osborn JW.

Hypertension. 2016 Oct;68(4):929-36. doi: 10.1161/HYPERTENSIONAHA.116.07993. Epub 2016 Aug 22.

9.

Differential role of afferent and efferent renal nerves in the maintenance of early- and late-phase Dahl S hypertension.

Foss JD, Fink GD, Osborn JW.

Am J Physiol Regul Integr Comp Physiol. 2016 Feb 1;310(3):R262-7. doi: 10.1152/ajpregu.00408.2015. Epub 2015 Dec 9.

10.

Intermittent electrical stimulation of the right cervical vagus nerve in salt-sensitive hypertensive rats: effects on blood pressure, arrhythmias, and ventricular electrophysiology.

Annoni EM, Xie X, Lee SW, Libbus I, KenKnight BH, Osborn JW, Tolkacheva EG.

Physiol Rep. 2015 Aug;3(8). pii: e12476. doi: 10.14814/phy2.12476.

11.

Inhibition of dipeptidyl peptidase 8/9 impairs preadipocyte differentiation.

Han R, Wang X, Bachovchin W, Zukowska Z, Osborn JW.

Sci Rep. 2015 Aug 5;5:12348. doi: 10.1038/srep12348.

12.

A mathematical model of salt-sensitive hypertension: the neurogenic hypothesis.

Averina VA, Othmer HG, Fink GD, Osborn JW.

J Physiol. 2015 Jul 15;593(14):3065-75. doi: 10.1113/jphysiol.2014.278317. Epub 2014 Oct 27. Review.

13.

Renal Denervation Prevents Immune Cell Activation and Renal Inflammation in Angiotensin II-Induced Hypertension.

Xiao L, Kirabo A, Wu J, Saleh MA, Zhu L, Wang F, Takahashi T, Loperena R, Foss JD, Mernaugh RL, Chen W, Roberts J 2nd, Osborn JW, Itani HA, Harrison DG.

Circ Res. 2015 Aug 28;117(6):547-57. doi: 10.1161/CIRCRESAHA.115.306010. Epub 2015 Jul 8.

14.

Erratum. The granin VGF promotes genesis of secretory vesicles, and regulates circulating catecholamine levels and blood pressure.

Fargali S, Garcia AL, Sadahiro M, Jiang C, Janssen WG, Lin WJ, Cogliani V, Elste A, Mortillo S, Cero C, Veitenheimer B, Graiani G, Pasinetti GM, Mahata SK, Osborn JW, Huntley GW, Phillips GR, Benson DL, Bartolomucci A, Salton SR.

FASEB J. 2015 Jun;29(6):2679. doi: 10.1096/fj.13-239509ERR. No abstract available.

15.

A novel method of selective ablation of afferent renal nerves by periaxonal application of capsaicin.

Foss JD, Wainford RD, Engeland WC, Fink GD, Osborn JW.

Am J Physiol Regul Integr Comp Physiol. 2015 Jan 15;308(2):R112-22. doi: 10.1152/ajpregu.00427.2014. Epub 2014 Nov 19.

16.

Comparison of arterial pressure and plasma ANG II responses to three methods of subcutaneous ANG II administration.

Kuroki MT, Fink GD, Osborn JW.

Am J Physiol Heart Circ Physiol. 2014 Sep 1;307(5):H670-9. doi: 10.1152/ajpheart.00922.2013. Epub 2014 Jul 3.

17.

Renal nerves: time for reassessment of their role in hypertension?

Fink GD, Osborn JW.

Am J Hypertens. 2014 Oct;27(10):1245-7. doi: 10.1093/ajh/hpu096. Epub 2014 May 28. No abstract available.

18.

The neurogenic phase of angiotensin II-salt hypertension is prevented by chronic intracerebroventricular administration of benzamil.

Osborn JW, Olson DM, Guzman P, Toney GM, Fink GD.

Physiol Rep. 2014 Feb 26;2(2):e00245. doi: 10.1002/phy2.245. eCollection 2014 Feb 1.

19.

Role of cardiac sympathetic nerves in blood pressure regulation.

Wehrwein EA, Yoshimoto M, Guzman P, Shah A, Kreulen DL, Osborn JW.

Auton Neurosci. 2014 Jul;183:30-5. doi: 10.1016/j.autneu.2014.02.005. Epub 2014 Mar 1.

20.

The granin VGF promotes genesis of secretory vesicles, and regulates circulating catecholamine levels and blood pressure.

Fargali S, Garcia AL, Sadahiro M, Jiang C, Janssen WG, Lin WJ, Cogliani V, Elste A, Mortillo S, Cero C, Veitenheimer B, Graiani G, Pasinetti GM, Mahata SK, Osborn JW, Huntley GW, Phillips GR, Benson DL, Bartolomucci A, Salton SR.

FASEB J. 2014 May;28(5):2120-33. doi: 10.1096/fj.13-239509. Epub 2014 Feb 4. Erratum in: FASEB J. 2015 Jun;29(6):2679.

21.

Targeting the sympathetic nervous system: critical issues in patient selection, efficacy, and safety of renal denervation.

Schlaich MP, Esler MD, Fink GD, Osborn JW, Euler DE.

Hypertension. 2014 Mar;63(3):426-32. doi: 10.1161/HYPERTENSIONAHA.113.02144. Epub 2013 Dec 9. Review. No abstract available.

22.

OVLT lesion decreases basal arterial pressure and the chronic hypertensive response to AngII in rats on a high-salt diet.

Collister JP, Olson MK, Nahey DB, Vieira AA, Osborn JW.

Physiol Rep. 2013 Oct;1(5):e00128. doi: 10.1002/phy2.128. Epub 2013 Oct 23.

23.

Restoring autonomic balance: future therapeutic targets.

Sobotka PA, Osborn JW, Paton JF.

EuroIntervention. 2013 May;9 Suppl R:R140-8. doi: 10.4244/EIJV9SRA24. Review.

PMID:
23732147
24.

Reply from V. A. Averina, H. G. Othmer, G. D. Fink and J. W. Osborn.

Averina VA, Othmer HG, Fink GD, Osborn JW.

J Physiol. 2013 Jun 1;591(11):2965. doi: 10.1113/jphysiol.2013.254607. No abstract available.

25.

Reversal of genetic salt-sensitive hypertension by targeted sympathetic ablation.

Foss JD, Fink GD, Osborn JW.

Hypertension. 2013 Apr;61(4):806-11. doi: 10.1161/HYPERTENSIONAHA.111.00474. Epub 2013 Feb 4.

26.

Effects of intrathecal kynurenate on arterial pressure during chronic osmotic stress in conscious rats.

Veitenheimer B, Osborn JW.

Am J Physiol Heart Circ Physiol. 2013 Jan 15;304(2):H303-10. doi: 10.1152/ajpheart.00629.2012. Epub 2012 Nov 16.

27.

High-fat food, sympathetic nerve activity, and hypertension: danger soon after the first bite?

Brooks VL, Osborn JW.

Hypertension. 2012 Dec;60(6):1387-8. doi: 10.1161/HYPERTENSIONAHA.112.201301. Epub 2012 Oct 22. No abstract available.

28.

Effect of global and regional sympathetic blockade on arterial pressure during water deprivation in conscious rats.

Veitenheimer BJ, Engeland WC, Guzman PA, Fink GD, Osborn JW.

Am J Physiol Heart Circ Physiol. 2012 Oct 15;303(8):H1022-34. doi: 10.1152/ajpheart.00413.2012. Epub 2012 Aug 17.

29.

A new conceptual paradigm for the haemodynamics of salt-sensitive hypertension: a mathematical modelling approach.

Averina VA, Othmer HG, Fink GD, Osborn JW.

J Physiol. 2012 Dec 1;590(23):5975-92. doi: 10.1113/jphysiol.2012.228619. Epub 2012 Aug 13.

30.

Sympathetic signatures of cardiovascular disease: a blueprint for development of targeted sympathetic ablation therapies.

Osborn JW, Kuroki MT.

Hypertension. 2012 Mar;59(3):545-7. doi: 10.1161/HYPERTENSIONAHA.111.182899. Epub 2012 Feb 6. No abstract available.

31.

Time-dependent changes in autonomic control of splanchnic vascular resistance and heart rate in ANG II-salt hypertension.

Kuroki MT, Guzman PA, Fink GD, Osborn JW.

Am J Physiol Heart Circ Physiol. 2012 Feb 1;302(3):H763-9. doi: 10.1152/ajpheart.00930.2011. Epub 2011 Nov 23.

32.

The role of the subfornical organ in angiotensin II-salt hypertension in the rat.

Osborn JW, Hendel MD, Collister JP, Ariza-Guzman PA, Fink GD.

Exp Physiol. 2012 Jan;97(1):80-8. doi: 10.1113/expphysiol.2011.060491. Epub 2011 Oct 3.

33.

The effect of cardiac sympathetic denervation through bilateral stellate ganglionectomy on electrical properties of the heart.

Xie X, Visweswaran R, Guzman PA, Smith RM, Osborn JW, Tolkacheva EG.

Am J Physiol Heart Circ Physiol. 2011 Jul;301(1):H192-9. doi: 10.1152/ajpheart.01149.2010. Epub 2011 Apr 15.

34.

Neural mechanisms of angiotensin II-salt hypertension: implications for therapies targeting neural control of the splanchnic circulation.

Osborn JW, Fink GD, Kuroki MT.

Curr Hypertens Rep. 2011 Jun;13(3):221-8. doi: 10.1007/s11906-011-0188-9. Review.

36.

Role of spinal V1a receptors in regulation of arterial pressure during acute and chronic osmotic stress.

Veitenheimer B, Osborn JW.

Am J Physiol Regul Integr Comp Physiol. 2011 Feb;300(2):R460-9. doi: 10.1152/ajpregu.00371.2010. Epub 2010 Dec 1.

37.

Effect of intracerebroventricular benzamil on cardiovascular and central autonomic responses to DOCA-salt treatment.

Abrams JM, Engeland WC, Osborn JW.

Am J Physiol Regul Integr Comp Physiol. 2010 Dec;299(6):R1500-10. doi: 10.1152/ajpregu.00431.2010. Epub 2010 Oct 6.

38.

Does enhanced respiratory-sympathetic coupling contribute to peripheral neural mechanisms of angiotensin II-salt hypertension?

Toney GM, Pedrino GR, Fink GD, Osborn JW.

Exp Physiol. 2010 May;95(5):587-94. doi: 10.1113/expphysiol.2009.047399. Epub 2010 Mar 12.

39.

Chronic angiotensin II infusion causes differential responses in regional sympathetic nerve activity in rats.

Yoshimoto M, Miki K, Fink GD, King A, Osborn JW.

Hypertension. 2010 Mar;55(3):644-51. doi: 10.1161/HYPERTENSIONAHA.109.145110. Epub 2010 Jan 25.

40.

Direct assessment of organ specific sympathetic nervous system activity in normal and cardiovascular disease states.

Knuepfer MM, Osborn JW.

Exp Physiol. 2010 Jan;95(1):32-3. doi: 10.1113/expphysiol.2008.045492. No abstract available.

41.

Region-specific changes in sympathetic nerve activity in angiotensin II-salt hypertension in the rat.

Osborn JW, Fink GD.

Exp Physiol. 2010 Jan;95(1):61-8. doi: 10.1113/expphysiol.2008.046326. Epub 2009 Aug 28. Review.

42.

Current computational models do not reveal the importance of the nervous system in long-term control of arterial pressure.

Osborn JW, Averina VA, Fink GD.

Exp Physiol. 2009 Apr;94(4):389-96. doi: 10.1113/expphysiol.2008.043281.

43.

Commentary on 'Understanding the contribution of Guyton's large circulatory model to long-term control of arterial pressure'.

Osborn JW, Averina VA, Fink GD.

Exp Physiol. 2009 Apr;94(4):388-9. doi: 10.1113/expphysiol.2008.046516. No abstract available.

44.

Effect of stellate ganglionectomy on basal cardiovascular function and responses to beta1-adrenoceptor blockade in the rat.

Yoshimoto M, Wehrwein EA, Novotny M, Swain GM, Kreulen DL, Osborn JW.

Am J Physiol Heart Circ Physiol. 2008 Dec;295(6):H2447-54. doi: 10.1152/ajpheart.00958.2008. Epub 2008 Oct 17.

45.

A model of growth restraints to explain the development and evolution of tooth shapes in mammals.

Osborn JW.

J Theor Biol. 2008 Dec 7;255(3):338-43. doi: 10.1016/j.jtbi.2008.09.008. Epub 2008 Sep 18.

PMID:
18838080
46.

Proclination of lower incisors: a design to maximize food penetration and minimize torque.

Paphangkorakit J, Osborn JW.

J Oral Rehabil. 2008 Nov;35(11):870-4. doi: 10.1111/j.1365-2842.2008.01884.x. Epub 2008 Aug 18.

PMID:
18713308
47.

A role for benzamil-sensitive proteins of the central nervous system in the pathogenesis of salt-dependent hypertension.

Abrams JM, Osborn JW.

Clin Exp Pharmacol Physiol. 2008 May;35(5-6):687-94. doi: 10.1111/j.1440-1681.2008.04929.x. Review.

48.

Effect of peripheral sympathetic nerve dysfunction on salt sensitivity of arterial pressure.

Osborn JW, Collister JP, Guzman P.

Clin Exp Pharmacol Physiol. 2008 Mar;35(3):273-9. Epub 2007 Oct 30.

PMID:
17973927
49.

Splanchnic circulation is a critical neural target in angiotensin II salt hypertension in rats.

King AJ, Osborn JW, Fink GD.

Hypertension. 2007 Sep;50(3):547-56. Epub 2007 Jul 23.

50.

Circulating angiotensin II and dietary salt: converging signals for neurogenic hypertension.

Osborn JW, Fink GD, Sved AF, Toney GM, Raizada MK.

Curr Hypertens Rep. 2007 Jun;9(3):228-35. Review.

PMID:
17519130

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