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Items: 1 to 50 of 469

1.

Stand-up test overestimates the decline of locomotor function in taller people: a cross-sectional analysis of data from the Kameda Health Study.

Miyamoto R, Sawada SS, Gando Y, Matsushita M, Kawakami R, Muranaga S, Osawa Y, Ishii K, Oka K.

J Phys Ther Sci. 2019 Feb;31(2):175-184. doi: 10.1589/jpts.31.175. Epub 2019 Feb 7.

2.

What factors predict ceramic liner malseating after ceramic-on-ceramic total hip arthroplasty?

Higuchi Y, Seki T, Takegami Y, Osawa Y, Kusano T, Ishiguro N.

Orthop Traumatol Surg Res. 2019 Mar 7. pii: S1877-0568(19)30056-8. doi: 10.1016/j.otsr.2019.01.009. [Epub ahead of print]

PMID:
30853457
3.

L233P mutation in the bovine leukemia virus Tax protein depresses endothelial cell recruitment and tumorigenesis in athymic nude mice.

Mori H, Tomiyasu T, Nishiyama K, Matsumoto M, Osawa Y, Okazaki K.

Arch Virol. 2019 Mar 8. doi: 10.1007/s00705-019-04191-3. [Epub ahead of print]

PMID:
30848389
4.

Trousseau syndrome in a patient with advanced oral squamous cell carcinoma: a case report.

Aoyama KI, Tamura M, Uchibori M, Nakanishi Y, Arai T, Aoki T, Osawa Y, Kaneko A, Ota Y.

J Med Case Rep. 2019 Jan 29;13(1):26. doi: 10.1186/s13256-018-1833-6.

5.

Whole-liver radiotherapy for diffuse liver metastases improves liver enzymes and related factors.

Ito K, Osawa Y, Shimizuguchi T, Ogawa H, Nihei K, Karasawa K.

Acta Oncol. 2019 Jan 7:1-3. doi: 10.1080/0284186X.2018.1548776. [Epub ahead of print] No abstract available.

PMID:
30616443
6.

Postoperative Complications Associated With Spine Surgery in Patients Older Than 90 Years: A Multicenter Retrospective Study.

Kobayashi K, Imagama S, Sato K, Kato F, Kanemura T, Yoshihara H, Sakai Y, Shinjo R, Hachiya Y, Osawa Y, Matsubara Y, Ando K, Nishida Y, Ishiguro N.

Global Spine J. 2018 Dec;8(8):887-891. doi: 10.1177/2192568218767430. Epub 2018 Apr 19. Review.

7.

A Mouse Distraction Osteogenesis Model.

Fujio M, Osawa Y, Matsushita M, Ogisu K, Tsuchiya S, Kitoh H, Hibi H.

J Vis Exp. 2018 Nov 14;(141). doi: 10.3791/57925.

PMID:
30507900
8.

Low mucosal-associated invariant T-cell number in peripheral blood of patients with immune thrombocytopenia and their response to prednisolone.

Maekawa T, Osawa Y, Okada Y, Tachi N, Teramoto M, Kawamura T, Horiuchi T, Kato S, Kobayashi A, Kobayashi S, Sato K, Kimura F.

PLoS One. 2018 Nov 8;13(11):e0207149. doi: 10.1371/journal.pone.0207149. eCollection 2018.

9.

Cytokine and chemokine signatures associated with hepatitis B surface antigen loss in hepatitis B patients.

Yoshio S, Mano Y, Doi H, Shoji H, Shimagaki T, Sakamoto Y, Kawai H, Matsuda M, Mori T, Osawa Y, Korenaga M, Sugiyama M, Mizokami M, Mita E, Katayama K, Tanaka J, Kanto T.

JCI Insight. 2018 Oct 18;3(20). pii: 122268. doi: 10.1172/jci.insight.122268.

10.

Wnt/β-Catenin Signaling as a Potential Target for the Treatment of Liver Cirrhosis Using Antifibrotic Drugs.

Nishikawa K, Osawa Y, Kimura K.

Int J Mol Sci. 2018 Oct 10;19(10). pii: E3103. doi: 10.3390/ijms19103103. Review.

11.

Relative validity of brief-type self-administered diet history questionnaire among very old Japanese aged 80 years or older.

Kobayashi S, Yuan X, Sasaki S, Osawa Y, Hirata T, Abe Y, Takayama M, Arai Y, Masui Y, Ishizaki T.

Public Health Nutr. 2019 Feb;22(2):212-222. doi: 10.1017/S1368980018002331. Epub 2018 Oct 2.

12.

Correction: Myeloproliferative leukemia protein activation directly induces fibrocyte differentiation to cause myelofibrosis.

Maekawa T, Osawa Y, Izumi T, Nagao S, Takano K, Okada Y, Tachi N, Teramoto M, Kawamura T, Horiuchi T, Saga R, Kato S, Yamamura T, Watanabe J, Kobayashi A, Kobayashi S, Sato K, Hashimoto M, Suzu S, Kimura F.

Leukemia. 2018 Dec;32(12):2729-2730. doi: 10.1038/s41375-018-0237-3.

PMID:
30232464
13.

Knee extension rate of velocity development affects walking performance differently in men and women.

Osawa Y, Studenski SA, Ferrucci L.

Exp Gerontol. 2018 Oct 2;112:63-67. doi: 10.1016/j.exger.2018.09.005. Epub 2018 Sep 12.

PMID:
30218708
14.

Bronchodilator Reversibility Occurring during the Acute Phase of Paragonimiasis westermani Infection.

Harada T, Kawasaki Y, Tsukada A, Osawa Y, Takami H, Yamaguchi K, Kurai J, Yamasaki A, Shimizu E.

Intern Med. 2019 Jan 15;58(2):297-300. doi: 10.2169/internalmedicine.0401-17. Epub 2018 Aug 24.

15.

Chaperone Activity and Dimerization Properties of Hsp90α and Hsp90β in Glucocorticoid Receptor Activation by the Multiprotein Hsp90/Hsp70-Dependent Chaperone Machinery.

Morishima Y, Mehta RK, Yoshimura M, Lau M, Southworth DR, Lawrence TS, Pratt WB, Nyati MK, Osawa Y.

Mol Pharmacol. 2018 Sep;94(3):984-991. doi: 10.1124/mol.118.112516. Epub 2018 Jun 25.

PMID:
29941666
16.

Cementless total hip arthroplasty for osteonecrosis and osteoarthritis produce similar results at ten years follow-up when matched for age and gender.

Osawa Y, Seki T, Takegami Y, Kusano T, Makida K, Ishiguro N.

Int Orthop. 2018 Jul;42(7):1683-1688. doi: 10.1007/s00264-018-3987-7. Epub 2018 May 24.

PMID:
29797167
17.

Rate of muscle contraction is associated with cognition in women, not in men.

Tian Q, Osawa Y, Resnick SM, Ferrucci L, Studenski SA.

J Gerontol A Biol Sci Med Sci. 2018 May 8. doi: 10.1093/gerona/gly115. [Epub ahead of print]

PMID:
29741590
18.

Tumor necrosis factor-α-mediated hepatocyte apoptosis stimulates fibrosis in the steatotic liver in mice.

Osawa Y, Kojika E, Hayashi Y, Kimura M, Nishikawa K, Yoshio S, Doi H, Kanto T, Kimura K.

Hepatol Commun. 2018 Feb 13;2(4):407-420. doi: 10.1002/hep4.1158. eCollection 2018 Apr.

19.

The full-length cytochrome P450 enzyme CYP102A1 dimerizes at its reductase domains and has flexible heme domains for efficient catalysis.

Zhang H, Yokom AL, Cheng S, Su M, Hollenberg PF, Southworth DR, Osawa Y.

J Biol Chem. 2018 May 18;293(20):7727-7736. doi: 10.1074/jbc.RA117.000600. Epub 2018 Apr 4.

PMID:
29618513
20.

CBL mutation and MEFV single-nucleotide variant are important genetic predictors of tumor reduction in glucocorticoid-treated patients with chronic myelomonocytic leukemia.

Watanabe J, Sato K, Osawa Y, Horiuchi T, Kato S, Hikota-Saga R, Maekawa T, Yamamura T, Kobayashi A, Kobayashi S, Kimura F.

Int J Hematol. 2018 Jul;108(1):47-57. doi: 10.1007/s12185-018-2436-0. Epub 2018 Mar 29.

PMID:
29600428
21.

Knee extension rate of torque development and peak torque: associations with lower extremity function.

Osawa Y, Studenski SA, Ferrucci L.

J Cachexia Sarcopenia Muscle. 2018 Jun;9(3):530-539. doi: 10.1002/jcsm.12285. Epub 2018 Mar 23.

22.

Do femoral head collapse and the contralateral condition affect patient-reported quality of life and referral pain in patients with osteonecrosis of the femoral head?

Osawa Y, Seki T, Takegami Y, Kasai T, Higuchi Y, Ishiguro N.

Int Orthop. 2018 Jul;42(7):1463-1468. doi: 10.1007/s00264-018-3867-1. Epub 2018 Mar 9.

PMID:
29523954
23.

Absorption and metabolism of orally administered collagen hydrolysates evaluated by the vascularly perfused rat intestine and liver in situ.

Osawa Y, Mizushige T, Jinno S, Sugihara F, Inoue N, Tanaka H, Kabuyama Y.

Biomed Res. 2018;39(1):1-11. doi: 10.2220/biomedres.39.1.

24.

Preoperative Canal Bone Ratio is Related to High-Degree Stress Shielding: A Minimum 5-Year Follow-Up Study of a Proximally Hydroxyapatite-Coated Straight Tapered Titanium Femoral Component.

Kusano T, Seki T, Higuchi Y, Takegami Y, Osawa Y, Ishiguro N.

J Arthroplasty. 2018 Jun;33(6):1764-1769. doi: 10.1016/j.arth.2017.12.019. Epub 2017 Dec 28.

PMID:
29366730
25.

Functional characterization of the G162R and D216H genetic variants of human CYP17A1.

Capper CP, Liu J, McIntosh LR, Larios JM, Johnson MD, Hollenberg PF, Osawa Y, Auchus RJ, Rae JM.

J Steroid Biochem Mol Biol. 2018 Apr;178:159-166. doi: 10.1016/j.jsbmb.2017.12.002. Epub 2017 Dec 9.

PMID:
29229304
26.

Posterior Reversible Encephalopathy Syndrome after Lenvatinib Therapy in a Patient with Anaplastic Thyroid Carcinoma.

Osawa Y, Gozawa R, Koyama K, Nakayama T, Sagoh T, Sunaga H.

Intern Med. 2018 Apr 1;57(7):1015-1019. doi: 10.2169/internalmedicine.9593-17. Epub 2017 Dec 8.

27.

Patient-reported outcomes in patients who undergo total hip arthroplasty after periacetabular osteotomy.

Osawa Y, Hasegawa Y, Seki T, Takegami Y, Amano T, Ishiguro N.

J Orthop Sci. 2018 Mar;23(2):346-349. doi: 10.1016/j.jos.2017.11.001. Epub 2017 Nov 26.

PMID:
29187291
28.

TAK1 inhibition ameliorates survival from graft-versus-host disease in an allogeneic murine marrow transplantation model.

Kobayashi A, Kobayashi S, Miyai K, Osawa Y, Horiuchi T, Kato S, Maekawa T, Yamamura T, Watanabe J, Sato K, Tsuda H, Kimura F.

Int J Hematol. 2018 Feb;107(2):222-229. doi: 10.1007/s12185-017-2345-7. Epub 2017 Oct 12.

PMID:
29027124
29.

Morphological Analysis of Live Undifferentiated Cells Derived from Induced Pluripotent Stem Cells.

Osawa Y, Miyamoto T, Ohno S, Ohno E.

Stem Cells Dev. 2018 Jan 1;27(1):1-9. doi: 10.1089/scd.2017.0112. Epub 2017 Dec 5.

PMID:
28978257
30.

Safety, Tolerability, and Preliminary Efficacy of the Anti-Fibrotic Small Molecule PRI-724, a CBP/β-Catenin Inhibitor, in Patients with Hepatitis C Virus-related Cirrhosis: A Single-Center, Open-Label, Dose Escalation Phase 1 Trial.

Kimura K, Ikoma A, Shibakawa M, Shimoda S, Harada K, Saio M, Imamura J, Osawa Y, Kimura M, Nishikawa K, Okusaka T, Morita S, Inoue K, Kanto T, Todaka K, Nakanishi Y, Kohara M, Mizokami M.

EBioMedicine. 2017 Sep;23:79-87. doi: 10.1016/j.ebiom.2017.08.016. Epub 2017 Aug 19.

31.

Activated FGFR3 promotes bone formation via accelerating endochondral ossification in mouse model of distraction osteogenesis.

Osawa Y, Matsushita M, Hasegawa S, Esaki R, Fujio M, Ohkawara B, Ishiguro N, Ohno K, Kitoh H.

Bone. 2017 Dec;105:42-49. doi: 10.1016/j.bone.2017.05.016. Epub 2017 Aug 10.

PMID:
28802681
32.

Satisfaction with dietary life affects oral health-related quality of life and subjective well-being in very elderly people.

Iinuma T, Arai Y, Takayama M, Takayama M, Abe Y, Osawa Y, Fukumoto M, Fukui Y, Shioda Y, Hirose N, Komiyama K, Gionhaku N.

J Oral Sci. 2017;59(2):207-213. doi: 10.2334/josnusd.16-0414.

33.

Total Hip Arthroplasty After Transtrochanteric Rotational Osteotomy for Osteonecrosis of the Femoral Head: A Mean 10-Year Follow-Up.

Osawa Y, Seki T, Morita D, Takegami Y, Okura T, Ishiguro N.

J Arthroplasty. 2017 Oct;32(10):3088-3092. doi: 10.1016/j.arth.2017.05.020. Epub 2017 May 18.

PMID:
28634093
34.

Pro-angiogenic TIE-2-expressing monocytes/TEMs as a biomarker of the effect of sorafenib in patients with advanced hepatocellular carcinoma.

Shoji H, Yoshio S, Mano Y, Doi H, Sugiyama M, Osawa Y, Kimura K, Arai T, Itokawa N, Atsukawa M, Aoki Y, Fukai M, Taketomi A, Mizokami M, Kanto T.

Int J Cancer. 2017 Sep 1;141(5):1011-1017. doi: 10.1002/ijc.30804. Epub 2017 Jun 8.

35.

Myeloproliferative leukemia protein activation directly induces fibrocyte differentiation to cause myelofibrosis.

Maekawa T, Osawa Y, Izumi T, Nagao S, Takano K, Okada Y, Tachi N, Teramoto M, Kawamura T, Horiuchi T, Saga R, Kato S, Yamamura T, Watanabe J, Kobayashi A, Kobayashi S, Sato K, Hashimoto M, Suzu S, Kimura F.

Leukemia. 2017 Dec;31(12):2709-2716. doi: 10.1038/leu.2017.112. Epub 2017 Apr 3. Erratum in: Leukemia. 2018 Dec;32(12):2729-2730.

PMID:
28386106
36.

Selective inhibitor of Wnt/β-catenin/CBP signaling ameliorates hepatitis C virus-induced liver fibrosis in mouse model.

Tokunaga Y, Osawa Y, Ohtsuki T, Hayashi Y, Yamaji K, Yamane D, Hara M, Munekata K, Tsukiyama-Kohara K, Hishima T, Kojima S, Kimura K, Kohara M.

Sci Rep. 2017 Mar 23;7(1):325. doi: 10.1038/s41598-017-00282-w.

37.

Identification of dietary patterns and their relationships with general and oral health in the very old.

Osawa Y, Arai Y, Takayama M, Hirata T, Kawasaki M, Abe Y, Iinuma T, Sasaki S, Hirose N.

Asia Pac J Clin Nutr. 2017 Mar;26(2):262-270. doi: 10.6133/apjcn.022016.02.

38.

Donor cell leukemia arising from preleukemic clones with a novel germline DDX41 mutation after allogenic hematopoietic stem cell transplantation.

Kobayashi S, Kobayashi A, Osawa Y, Nagao S, Takano K, Okada Y, Tachi N, Teramoto M, Kawamura T, Horiuchi T, Kato S, Maekawa T, Yamamura T, Watanabe J, Harada Y, Harada H, Sato K, Kimura F.

Leukemia. 2017 Apr;31(4):1020-1022. doi: 10.1038/leu.2017.44. Epub 2017 Feb 14. No abstract available.

PMID:
28194039
39.

Long-term outcomes of transtrochanteric rotational osteotomy for non-traumatic osteonecrosis of the femoral head.

Morita D, Hasegawa Y, Okura T, Osawa Y, Ishiguro N.

Bone Joint J. 2017 Feb;99-B(2):175-183. doi: 10.1302/0301-620X.99B2.BJJ-2016-0417.R2.

PMID:
28148658
40.

Validation of Questionnaire-Assessed Physical Activity in Comparison With Objective Measures Using Accelerometers and Physical Performance Measures Among Community-Dwelling Adults Aged ≥85 Years in Tokyo, Japan.

Oguma Y, Osawa Y, Takayama M, Abe Y, Tanaka S, Lee IM, Arai Y.

J Phys Act Health. 2017 Apr;14(4):245-252. doi: 10.1123/jpah.2016-0208. Epub 2016 Dec 5.

PMID:
27918699
41.

Total Hip Arthroplasty After Periacetabular and Intertrochanteric Valgus Osteotomy.

Osawa Y, Hasegawa Y, Okura T, Morita D, Ishiguro N.

J Arthroplasty. 2017 Mar;32(3):857-861. doi: 10.1016/j.arth.2016.08.023. Epub 2016 Aug 26.

PMID:
27667535
42.

Relationships of Muscle Echo Intensity with Walking Ability and Physical Activity in the Very Old Population.

Osawa Y, Arai Y, Oguma Y, Hirata T, Abe Y, Azuma K, Takayama M, Hirose N.

J Aging Phys Act. 2017 Apr;25(2):189-195. doi: 10.1123/japa.2015-0203. Epub 2016 Sep 6.

PMID:
27623344
43.

What factors predict the failure of curved intertrochanteric varus osteotomy for the osteonecrosis of the femoral head?

Okura T, Hasegawa Y, Morita D, Osawa Y, Ishiguro N.

Arch Orthop Trauma Surg. 2016 Dec;136(12):1647-1655. Epub 2016 Aug 29.

PMID:
27573979
44.

Significant Improvement of Antithrombotic Responses to Clopidogrel by Use of a Novel Conjugate as Revealed in an Arterial Model of Thrombosis.

Zhang H, Lauver DA, Wang H, Sun D, Hollenberg PF, Chen YE, Osawa Y, Eitzman DT.

J Pharmacol Exp Ther. 2016 Oct;359(1):11-7. doi: 10.1124/jpet.116.236034. Epub 2016 Aug 10.

45.

Improved method for assembly of hemeprotein neuronal NO-synthase heterodimers.

Morishima Y, Zhang H, Lau M, Osawa Y.

Anal Biochem. 2016 Oct 15;511:24-6. doi: 10.1016/j.ab.2016.07.031. Epub 2016 Jul 31.

46.

Feasibility of intermittent back-filtrate infusion hemodiafiltration to reduce intradialytic hypotension in patients with cardiovascular instability: a pilot study.

Koda Y, Aoike I, Hasegawa S, Osawa Y, Nakagawa Y, Iwabuchi F, Iwahashi C, Sugimoto T, Kikutani T.

Clin Exp Nephrol. 2017 Apr;21(2):324-332. doi: 10.1007/s10157-016-1270-z. Epub 2016 Apr 28.

47.

Significantly Poor Outcomes of Total Hip Arthroplasty After Failed Periacetabular Osteotomy.

Osawa Y, Hasegawa Y, Seki T, Amano T, Higuchi Y, Ishiguro N.

J Arthroplasty. 2016 Sep;31(9):1904-9. doi: 10.1016/j.arth.2016.02.056. Epub 2016 Mar 4.

PMID:
27036922
48.

Inhibition of Cyclic Adenosine Monophosphate (cAMP)-response Element-binding Protein (CREB)-binding Protein (CBP)/β-Catenin Reduces Liver Fibrosis in Mice.

Osawa Y, Oboki K, Imamura J, Kojika E, Hayashi Y, Hishima T, Saibara T, Shibasaki F, Kohara M, Kimura K.

EBioMedicine. 2015 Oct 8;2(11):1751-8. doi: 10.1016/j.ebiom.2015.10.010. eCollection 2015 Nov.

49.

Outpatient Myelography: A Prospective Trial Comparing Complications after Myelography between Outpatients and Inpatients in Japan.

Matsumoto T, Imagama S, Inoue H, Aoki T, Ishiguro N, Osawa Y.

Asian Spine J. 2015 Dec;9(6):928-34. doi: 10.4184/asj.2015.9.6.928. Epub 2015 Dec 8.

50.

Gene therapy for ovarian cancer using carbonyl reductase 1 DNA with a polyamidoamine dendrimer in mouse models.

Kobayashi A, Yokoyama Y, Osawa Y, Miura R, Mizunuma H.

Cancer Gene Ther. 2016 Jan;23(1):24-8. doi: 10.1038/cgt.2015.61. Epub 2015 Nov 20.

PMID:
26584532

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