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Items: 1 to 50 of 1080

1.

Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2.

Osawa T, Shimamura T, Saito K, Hasegawa Y, Ishii N, Nishida M, Ando R, Kondo A, Anwar M, Tsuchida R, Hino S, Sakamoto A, Igarashi K, Saitoh K, Kato K, Endo K, Yamano S, Kanki Y, Matsumura Y, Minami T, Tanaka T, Anai M, Wada Y, Wanibuchi H, Hayashi M, Hamada A, Yoshida M, Yachida S, Nakao M, Sakai J, Aburatani H, Shibuya M, Hanada K, Miyano S, Soga T, Kodama T.

Cell Rep. 2019 Oct 1;29(1):89-103.e7. doi: 10.1016/j.celrep.2019.08.087.

2.

Synthesis of 2'-C,4'-C-Methyleneoxy-Bridged Thymidine Derivatives and Properties of Modified Oligonucleotides.

Osawa T, Kim H, Shoji M, Saijo M, Dohi M, Ito Y, Obika S, Hari Y.

J Org Chem. 2019 Oct 10. doi: 10.1021/acs.joc.9b01496. [Epub ahead of print]

PMID:
31565938
3.

Endocrinological characterization of an ovarian sex cord-stromal tumor with a Sertoli cell pattern in a Japanese Black cow.

El-Sheikh Ali H, Kitahara G, Nibe K, Osawa T.

Reprod Domest Anim. 2019 Aug 26. doi: 10.1111/rda.13556. [Epub ahead of print]

PMID:
31448448
4.

Synthesis of Belt- and Möbius-Shaped Cycloparaphenylenes by Rhodium-Catalyzed Alkyne Cyclotrimerization.

Nishigaki S, Shibata Y, Nakajima A, Okajima H, Masumoto Y, Osawa T, Muranaka A, Sugiyama H, Horikawa A, Uekusa H, Koshino H, Uchiyama M, Sakamoto A, Tanaka K.

J Am Chem Soc. 2019 Sep 25;141(38):14955-14960. doi: 10.1021/jacs.9b06197. Epub 2019 Aug 22.

PMID:
31418559
5.

Daily calving frequency and preterm calving is not associated with lunar cycle but preterm calving is associated with weather conditions in Japanese Black cows.

Sasaki Y, Kitai N, Uematsu M, Kitahara G, Osawa T.

PLoS One. 2019 Jul 23;14(7):e0220255. doi: 10.1371/journal.pone.0220255. eCollection 2019.

6.

Development of the Japanese version of the health-related quality of life questionnaire for bladder cancer patients using the Bladder Cancer Index: A pilot study.

Osawa T, Wei JT, Abe T, Kako Y, Murai S, Shinohara N.

Int J Urol. 2019 Oct;26(10):1016-1017. doi: 10.1111/iju.14073. Epub 2019 Jul 16. No abstract available.

PMID:
31311062
7.

Cost utility analysis of pharmacist counseling care for breast cancer chemotherapy outpatients.

Tanaka K, Tachi T, Hori A, Osawa T, Nagaya K, Makino T, Inoue S, Yasuda M, Mizui T, Nakada T, Goto C, Teramachi H.

Pharmazie. 2019 Jul 1;74(7):439-442. doi: 10.1691/ph.2019.9327.

PMID:
31288902
8.

Clinical trial protocol of doublet therapy and olanzapine for carboplatin-induced nausea and vomiting in patients with thoracic cancer: a multicentre phase II trial.

Iihara H, Shimokawa M, Gomyo T, Fujita Y, Yoshida T, Funaguchi N, Minato K, Kaito D, Osawa T, Yamada M, Hirose C, Suzuki A, Ohno Y.

BMJ Open. 2019 Jul 4;9(7):e028056. doi: 10.1136/bmjopen-2018-028056.

9.

[Midterm Outcomes and Therapeutic Effects of Total Cavopulmonary Connection (TCPC) Conversion].

Nonaka T, Wada Y, Osawa T, Sugiura J, Sakurai T, Sakurai H.

Kyobu Geka. 2019 Apr;72(4):275-281. Japanese.

PMID:
31266913
10.

Overt Proteinuria, Moderately Reduced eGFR and Their Combination Are Predictive of Severe Diabetic Retinopathy or Diabetic Macular Edema in Diabetes.

Yamamoto M, Fujihara K, Ishizawa M, Osawa T, Kaneko M, Ishiguro H, Matsubayashi Y, Seida H, Yamanaka N, Tanaka S, Kodama S, Hasebe H, Sone H.

Invest Ophthalmol Vis Sci. 2019 Jun 3;60(7):2685-2689. doi: 10.1167/iovs.19-26749.

PMID:
31242290
11.

Synthesis of the Methyl Analog of 2'-O,4'-C-Ethylene-Bridged 5-Methyluridine via Intramolecular Radical Cyclization and Properties of Modified Oligonucleotides.

Ito Y, Tsutsui N, Osawa T, Hari Y.

J Org Chem. 2019 Jul 19;84(14):9093-9100. doi: 10.1021/acs.joc.9b01035. Epub 2019 Jul 5.

PMID:
31241329
12.

Nivolumab-induced hypophysitis causing secondary adrenal insufficiency after transient ACTH elevation.

Sekizaki T, Kameda H, Oba C, Yong Cho K, Nakamura A, Miyoshi H, Osawa T, Shinohara N, Atsumi T.

Endocr J. 2019 Jun 19. doi: 10.1507/endocrj.EJ19-0076. [Epub ahead of print]

13.

Peptide TNIIIA2 Derived from Tenascin-C Contributes to Malignant Progression in Colitis-Associated Colorectal Cancer via β1-Integrin Activation in Fibroblasts.

Fujita M, Ito-Fujita Y, Iyoda T, Sasada M, Okada Y, Ishibashi K, Osawa T, Kodama H, Fukai F, Suzuki H.

Int J Mol Sci. 2019 Jun 5;20(11). pii: E2752. doi: 10.3390/ijms20112752.

14.

Outcome of maintenance systemic chemotherapy with drug-free interval for metastatic urothelial carcinoma.

Abe T, Minami K, Harabayashi T, Sazawa A, Chiba H, Kikuchi H, Miyata H, Matsumoto R, Osawa T, Maruyama S, IshizakiIshizaki J, Mochizuki T, Chiba S, Akino T, Murakumo M, Miyajima N, Tsuchiya K, Murai S, Shinohara N.

Jpn J Clin Oncol. 2019 Jun 12. pii: hyz084. doi: 10.1093/jjco/hyz084. [Epub ahead of print]

PMID:
31187865
15.

Changes of Cerebral Blood Volume During Robot-Assisted Laparoscopic Radical Prostatectomy: Observational Prospective Study Using Near-Infrared Time-Resolved Spectroscopy.

Tanaka N, Yamamoto M, Abe T, Osawa T, Matsumoto R, Shinohara N, Saito H, Uchida Y, Morimoto Y.

J Endourol. 2019 Jun 25. doi: 10.1089/end.2019.0217. [Epub ahead of print]

PMID:
31111734
16.

Intraoperative neuromonitoring during reverse shoulder arthroplasty.

Shinagawa S, Shitara H, Yamamoto A, Sasaki T, Ichinose T, Hamano N, Shimoyama D, Endo F, Kuboi T, Tajika T, Kobayashi T, Osawa T, Takagishi K, Chikuda H.

J Shoulder Elbow Surg. 2019 Aug;28(8):1617-1625. doi: 10.1016/j.jse.2019.01.007. Epub 2019 May 4.

PMID:
31064684
17.

Landscape heterogeneity in landform and land use provides functional resistance to gene flow in continuous Asian black bear populations.

Ohnishi N, Osawa T, Yamamoto T, Uno R.

Ecol Evol. 2019 Apr 5;9(8):4958-4968. doi: 10.1002/ece3.5102. eCollection 2019 Apr.

18.
19.

Relationship Between Number of Multiple Risk Factors and Coronary Artery Disease Risk With and Without Diabetes Mellitus.

Yamada-Harada M, Fujihara K, Osawa T, Yamamoto M, Kaneko M, Kitazawa M, Matsubayashi Y, Yamada T, Yamanaka N, Seida H, Ogawa W, Sone H.

J Clin Endocrinol Metab. 2019 Nov 1;104(11):5084-5090. doi: 10.1210/jc.2019-00168.

PMID:
30994885
20.

Atg2: A novel phospholipid transfer protein that mediates de novo autophagosome biogenesis.

Osawa T, Noda NN.

Protein Sci. 2019 Jun;28(6):1005-1012. doi: 10.1002/pro.3623. Epub 2019 Apr 29. Review.

21.

Pulse Pressure is a Stronger Predictor Than Systolic Blood Pressure for Severe Eye Diseases in Diabetes Mellitus.

Yamamoto M, Fujihara K, Ishizawa M, Osawa T, Kaneko M, Ishiguro H, Matsubayashi Y, Seida H, Yamanaka N, Tanaka S, Kodama S, Hasebe H, Sone H.

J Am Heart Assoc. 2019 Apr 16;8(8):e010627. doi: 10.1161/JAHA.118.010627.

22.

[Mid-aortic Syndrome Requiring Surgical Intervention during Infancy;Report of a Case].

Osawa T, Sakurai H, Nonaka T, Sakurai T, Sugiura J, Kozakai M, Wada Y.

Kyobu Geka. 2019 Mar;72(3):236-239. Japanese.

PMID:
30923303
23.

Relationship Between Balance Recovery From a Forward Fall and Lower-Limb Rate of Torque Development.

Ochi A, Ohko H, Hayashi T, Osawa T, Sugiyama Y, Nakamura S, Ibuki S, Ichihashi N.

J Mot Behav. 2019 Mar 27:1-8. doi: 10.1080/00222895.2019.1585743. [Epub ahead of print]

PMID:
30915901
24.

Atg2 mediates direct lipid transfer between membranes for autophagosome formation.

Osawa T, Kotani T, Kawaoka T, Hirata E, Suzuki K, Nakatogawa H, Ohsumi Y, Noda NN.

Nat Struct Mol Biol. 2019 Apr;26(4):281-288. doi: 10.1038/s41594-019-0203-4. Epub 2019 Mar 25.

PMID:
30911189
25.

The surface composition of asteroid 162173 Ryugu from Hayabusa2 near-infrared spectroscopy.

Kitazato K, Milliken RE, Iwata T, Abe M, Ohtake M, Matsuura S, Arai T, Nakauchi Y, Nakamura T, Matsuoka M, Senshu H, Hirata N, Hiroi T, Pilorget C, Brunetto R, Poulet F, Riu L, Bibring JP, Takir D, Domingue DL, Vilas F, Barucci MA, Perna D, Palomba E, Galiano A, Tsumura K, Osawa T, Komatsu M, Nakato A, Arai T, Takato N, Matsunaga T, Takagi Y, Matsumoto K, Kouyama T, Yokota Y, Tatsumi E, Sakatani N, Yamamoto Y, Okada T, Sugita S, Honda R, Morota T, Kameda S, Sawada H, Honda C, Yamada M, Suzuki H, Yoshioka K, Hayakawa M, Ogawa K, Cho Y, Shirai K, Shimaki Y, Hirata N, Yamaguchi A, Ogawa N, Terui F, Yamaguchi T, Takei Y, Saiki T, Nakazawa S, Tanaka S, Yoshikawa M, Watanabe S, Tsuda Y.

Science. 2019 Apr 19;364(6437):272-275. doi: 10.1126/science.aav7432. Epub 2019 Mar 19.

PMID:
30890589
26.

Combined supra-infrasellar approach to pituitary macroadenoma with oculomotor cistern extension: surgical strategy and experience.

Tosaka M, Shimizu T, Miyagishima T, Tanaka Y, Osawa T, Aihara M, Yamaguchi R, Yoshimoto Y.

Acta Neurochir (Wien). 2019 May;161(5):1025-1031. doi: 10.1007/s00701-019-03869-6. Epub 2019 Mar 12.

PMID:
30863890
27.

Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis.

Kidoya H, Muramatsu F, Shimamura T, Jia W, Satoh T, Hayashi Y, Naito H, Kunisaki Y, Arai F, Seki M, Suzuki Y, Osawa T, Akira S, Takakura N.

Nat Commun. 2019 Mar 6;10(1):1072. doi: 10.1038/s41467-019-09028-w.

28.

Nephrometry score correlated with tumor proliferative activity inT1 clear cell renal cell carcinoma.

Kikuchi H, Abe T, Matsumoto R, Osawa T, Maruyama S, Murai S, Shinohara N.

Urol Oncol. 2019 May;37(5):301.e19-301.e25. doi: 10.1016/j.urolonc.2019.02.005. Epub 2019 Feb 27.

29.

Length of lags in responses of milk yield and somatic cell score on test day to heat stress in Holsteins.

Hagiya K, Bamba I, Osawa T, Atagi Y, Takusari N, Itoh F, Yamazaki T.

Anim Sci J. 2019 May;90(5):613-618. doi: 10.1111/asj.13186. Epub 2019 Feb 27.

30.

Effect of Thoracic Gas Volume Changes on Body Composition Assessed by Air Displacement Plethysmography after Rapid Weight Loss and Regain in Elite Collegiate Wrestlers.

Kondo E, Shiose K, Yamada Y, Osawa T, Sagayama H, Motonaga K, Ouchi S, Kamei A, Nakajima K, Takahashi H, Okamura K.

Sports (Basel). 2019 Feb 19;7(2). pii: E48. doi: 10.3390/sports7020048.

31.

Feeding of 1-Kestose Induces Glutathione-S-Transferase Expression in Mouse Liver.

Tochio T, Ueno Y, Kitaura Y, Shinohara M, Kadota Y, Minoda K, Shimomura Y, Osawa T.

Foods. 2019 Feb 13;8(2). pii: E69. doi: 10.3390/foods8020069.

32.

Overview of current and future systemic therapy for metastatic renal cell carcinoma.

Osawa T, Takeuchi A, Kojima T, Shinohara N, Eto M, Nishiyama H.

Jpn J Clin Oncol. 2019 May 1;49(5):395-403. doi: 10.1093/jjco/hyz013. Review.

PMID:
30722031
33.

Silyl-pyridine-amine pincer-ligated iridium complexes for catalytic silane deuteration via room temperature C-D bond activation of benzene-d6.

Komuro T, Osawa T, Suzuki R, Mochizuki D, Higashi H, Tobita H.

Chem Commun (Camb). 2019 Jan 17;55(7):957-960. doi: 10.1039/c8cc09178a.

PMID:
30604784
34.

Higher pulse pressure predicts initiation of dialysis in Japanese patients with diabetes.

Osawa T, Fujihara K, Harada M, Yamamoto M, Ishizawa M, Suzuki H, Ishiguro H, Matsubayashi Y, Seida H, Yamanaka N, Tanaka S, Shimano H, Kodama S, Sone H.

Diabetes Metab Res Rev. 2019 Mar;35(3):e3120. doi: 10.1002/dmrr.3120. Epub 2019 Jan 16.

PMID:
30578707
35.

Numerical and Experimental Analyses of Three- Dimensional Unsteady Flow around a Micro-Pillar Subjected to Rotational Vibration.

Kaneko K, Osawa T, Kametani Y, Hayakawa T, Hasegawa Y, Suzuki H.

Micromachines (Basel). 2018 Dec 17;9(12). pii: E668. doi: 10.3390/mi9120668.

36.

Effect of family-oriented diabetes programs on glycemic control: A meta-analysis.

Kodama S, Morikawa S, Horikawa C, Ishii D, Fujihara K, Yamamoto M, Osawa T, Kitazawa M, Yamada T, Kato K, Tanaka S, Sone H.

Fam Pract. 2019 Jul 31;36(4):387-394. doi: 10.1093/fampra/cmy112.

PMID:
30423118
37.

Membrane-binding domains in autophagy.

Osawa T, Alam JM, Noda NN.

Chem Phys Lipids. 2019 Jan;218:1-9. doi: 10.1016/j.chemphyslip.2018.11.001. Epub 2018 Nov 8. Review.

PMID:
30414879
38.

[Predictors of Nivolumab-Induced Skin Reactions].

Osawa T, Inoue S, Umeda M, Hasegawa T, Makino T, Hori A, Tanaka K, Yasuda M, Mizui T, Sawa T, Sugiyama Y, Goto C.

Gan To Kagaku Ryoho. 2018 Oct;45(10):1533-1535. Japanese.

PMID:
30382069
39.

[Treatment Outcome of Axitinib for Metastatic Renal-Cell Carcinoma Patients].

Kusakabe N, Osawa T, Miyata H, Kikuchi H, Matsumoto R, Maruyama S, Abe T, Shinohara N.

Hinyokika Kiyo. 2018 Sep;64(9):353-358. doi: 10.14989/ActaUrolJap_64_9_353. Japanese.

PMID:
30369225
40.

Treatment patterns and outcomes in patients with unresectable or metastatic renal cell carcinoma in Japan.

Harada K, Nozawa M, Uemura M, Tatsugami K, Osawa T, Yamana K, Kimura G, Fujisawa M, Nonomura N, Eto M, Shinohara N, Tomita Y, Kondo Y, Ochi K, Anazawa Y, Uemura H.

Int J Urol. 2019 Feb;26(2):202-210. doi: 10.1111/iju.13830. Epub 2018 Oct 21.

PMID:
30345560
41.

Comparative study of lymph node dissection, and oncological outcomes of laparoscopic and open radical nephroureterectomy for patients with urothelial carcinoma of the upper urinary tract undergoing regional lymph node dissection.

Abe T, Kondo T, Harabayashi T, Takada N, Matsumoto R, Osawa T, Minami K, Nagamori S, Maruyama S, Murai S, Tanabe K, Shinohara N.

Jpn J Clin Oncol. 2018 Nov 1;48(11):1001-1011. doi: 10.1093/jjco/hyy128.

42.

Factors influencing the use of over-the-counter drugs and health foods/supplements.

Tachi T, Yoshida A, Kanematsu Y, Sugita I, Noguchi Y, Osawa T, Yasuda M, Mizui T, Goto C, Teramachi H.

Pharmazie. 2018 Oct 1;73(10):598-604. doi: 10.1691/ph.2018.8617.

PMID:
30223925
43.

Bladder cancer detection by urinary extracellular vesicle mRNA analysis.

Murakami T, Yamamoto CM, Akino T, Tanaka H, Fukuzawa N, Suzuki H, Osawa T, Tsuji T, Seki T, Harada H.

Oncotarget. 2018 Aug 28;9(67):32810-32821. doi: 10.18632/oncotarget.25998. eCollection 2018 Aug 28.

44.

Effects of a progressive walking program on the risk of developing locomotive syndrome in elderly Japanese people: a single-arm trial.

Yoshihara T, Ozaki H, Nakagata T, Natsume T, Kitada T, Ishihara Y, Deng P, Osawa T, Ishibashi M, Ishijima M, Kobayashi H, Machida S, Naito H.

J Phys Ther Sci. 2018 Sep;30(9):1180-1186. doi: 10.1589/jpts.30.1180. Epub 2018 Sep 4.

45.

Association of treatment-achieved HbA1c with incidence of coronary artery disease and severe eye disease in diabetes patients.

Harada M, Fujihara K, Osawa T, Yamamoto M, Kaneko M, Ishizawa M, Matsubayashi Y, Yamada T, Yamanaka N, Seida H, Kodama S, Ogawa W, Sone H.

Diabetes Metab. 2018 Sep 10. pii: S1262-3636(18)30167-8. doi: 10.1016/j.diabet.2018.08.009. [Epub ahead of print]

PMID:
30213710
46.

Photoredox-Catalyzed Deformylative 1,4-Addition of 2'-Deoxy-5'- O-phthalimidonucleosides for Synthesis of 5'-Carba Analogs of Nucleoside 5'-Phosphates.

Ito Y, Kimura A, Osawa T, Hari Y.

J Org Chem. 2018 Sep 21;83(18):10701-10708. doi: 10.1021/acs.joc.8b00637. Epub 2018 Sep 5.

PMID:
30136574
47.

Rapid on-site dual optical system to measure specific reactive oxygen species (O2-• and OCl-) in a tiny droplet of whole blood.

Kazumura K, Takeuchi K, Hara A, Miwa T, Hattori M, Wu Y, Morishita N, Tsuchiya H, Osawa T.

PLoS One. 2018 Aug 1;13(8):e0200573. doi: 10.1371/journal.pone.0200573. eCollection 2018.

48.

Selection on milk production and conformation traits during the last two decades in Japan.

Togashi K, Osawa T, Adachi K, Kurogi K, Tokunaka K, Yasumori T, Takahashi T, Moribe K.

Asian-Australas J Anim Sci. 2019 Feb;32(2):183-191. doi: 10.5713/ajas.18.0259. Epub 2018 Jul 26.

49.

Outcome and prognostic factors in metastatic urothelial carcinoma patients receiving second-line chemotherapy: an analysis of real-world clinical practice data in Japan.

Matsumoto R, Abe T, Ishizaki J, Kikuchi H, Harabayashi T, Minami K, Sazawa A, Mochizuki T, Akino T, Murakumo M, Osawa T, Maruyama S, Murai S, Shinohara N.

Jpn J Clin Oncol. 2018 Aug 1;48(8):771-776. doi: 10.1093/jjco/hyy094.

50.

Opioid Dose and Survival of Patients with Incurable Nonsmall Cell Lung Cancer: A Prospective Cohort Study.

Hasegawa T, Oguri T, Osawa T, Sawa T, Osaga S, Okuyama T, Uchida M, Maeno K, Fukuda S, Nishie H, Niimi A, Akechi T.

J Palliat Med. 2018 Oct;21(10):1436-1441. doi: 10.1089/jpm.2018.0044. Epub 2018 Jun 12.

PMID:
29893612

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