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Items: 1 to 50 of 256

1.

Precise tuning of disulfide crosslinking in mRNA polyplex micelles for optimizing extracellular and intracellular nuclease tolerability.

Dirisala A, Uchida S, Tockary TA, Yoshinaga N, Li J, Osawa S, Gorantla L, Fukushima S, Osada K, Kataoka K.

J Drug Target. 2018 Nov 30:1-39. doi: 10.1080/1061186X.2018.1550646. [Epub ahead of print]

PMID:
30499743
2.

Important contributions of sea-salt aerosols to atmospheric bromine cycle in the Antarctic coasts.

Hara K, Osada K, Yabuki M, Takashima H, Theys N, Yamanouchi T.

Sci Rep. 2018 Sep 14;8(1):13852. doi: 10.1038/s41598-018-32287-4.

3.

Development of monomorphic ventricular tachycardia in a patient with fever-induced Brugada syndrome.

Sato Y, Aizawa Y, Fujisawa T, Ito S, Katano K, Fuse N, Miyabe A, Osada K, Ishihara R, Tosaka A, Tamamura T, Mizumura T, Sugimura Y, Nakajima K, Katsumata Y, Nishiyama T, Kimura T, Furukawa Y, Takatsuki S, Kosaki K, Fukuda K.

J Arrhythm. 2018 Jun 4;34(4):465-468. doi: 10.1002/joa3.12068. eCollection 2018 Aug.

4.

Block Copolymer Micelles in Nanomedicine Applications.

Cabral H, Miyata K, Osada K, Kataoka K.

Chem Rev. 2018 Jul 25;118(14):6844-6892. doi: 10.1021/acs.chemrev.8b00199. Epub 2018 Jun 29.

5.

Oxytocin receptor signaling contributes to olfactory avoidance behavior induced by an unpleasant odorant.

Osada K, Ohta T, Takai R, Miyazono S, Kashiwayanagi M, Hidema S, Nishimori K.

Biol Open. 2018 Sep 26;7(9). pii: bio029140. doi: 10.1242/bio.029140.

6.

Glycine and succinic acid are effective indicators of the suppression of epithelial-mesenchymal transition by fucoxanthinol in colorectal cancer stem-like cells.

Terasaki M, Mima M, Kudoh S, Endo T, Maeda H, Hamada J, Osada K, Miyashita K, Mutoh M.

Oncol Rep. 2018 Jul;40(1):414-424. doi: 10.3892/or.2018.6398. Epub 2018 Apr 24.

PMID:
29693702
7.

Glycine Is a Predictor for a Suppressive Effect of Fucoxanthinol on Colonosphere Formation Under Hypoxia.

Terasaki M, Ogawa Y, Endo T, Maeda H, Hamada J, Osada K, Miyashita K, Mutoh M.

Anticancer Res. 2018 Apr;38(4):2169-2179.

PMID:
29599336
8.

Etizolam attenuates the reduction in cutaneous temperature induced in mice by exposure to synthetic predator odor.

Miyazono S, Hasegawa K, Miyazaki S, Sakakima H, Konno S, Meguro S, Sasajima H, Noguchi T, Osada K, Kashiwayanagi M.

Eur J Pharmacol. 2018 Apr 5;824:157-162. doi: 10.1016/j.ejphar.2018.02.015. Epub 2018 Feb 10.

PMID:
29438703
9.

Gold nanoparticle core-europium(iii) chelate fluorophore-doped silica shell hybrid nanocomposites for the lateral flow immunoassay of human thyroid stimulating hormone with a dual signal readout.

Preechakasedkit P, Osada K, Katayama Y, Ruecha N, Suzuki K, Chailapakul O, Citterio D.

Analyst. 2018 Jan 21;143(2):564-570. doi: 10.1039/c7an01799e. Epub 2017 Dec 20.

PMID:
29260807
10.

Effects of eicosapentaenoic acid and docosahexaenoic acid on anxiety-like behavior in socially isolated rats.

Oshima Y, Watanabe T, Endo S, Hata S, Watanabe T, Osada K, Takenaka A.

Biosci Biotechnol Biochem. 2018 Apr;82(4):716-723. doi: 10.1080/09168451.2017.1403888. Epub 2017 Dec 1.

PMID:
29191085
11.

Polyplex Micelles with Phenylboronate/Gluconamide Cross-Linking in the Core Exerting Promoted Gene Transfection through Spatiotemporal Responsivity to Intracellular pH and ATP Concentration.

Yoshinaga N, Ishii T, Naito M, Endo T, Uchida S, Cabral H, Osada K, Kataoka K.

J Am Chem Soc. 2017 Dec 27;139(51):18567-18575. doi: 10.1021/jacs.7b08816. Epub 2017 Dec 14.

PMID:
29188718
12.

Thrombomodulin alfa attenuates the procoagulant effect and cytotoxicity of extracellular histones through the promotion of protein C activation.

Osada K, Minami T, Arioka T, Sakai T, Tawara S, Kawasaki K, Fareed J, Matsuzaki O.

Thromb Res. 2017 Dec;160:51-57. doi: 10.1016/j.thromres.2017.10.019. Epub 2017 Oct 27.

PMID:
29101790
13.

Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain.

Anraku Y, Kuwahara H, Fukusato Y, Mizoguchi A, Ishii T, Nitta K, Matsumoto Y, Toh K, Miyata K, Uchida S, Nishina K, Osada K, Itaka K, Nishiyama N, Mizusawa H, Yamasoba T, Yokota T, Kataoka K.

Nat Commun. 2017 Oct 17;8(1):1001. doi: 10.1038/s41467-017-00952-3.

14.

Therapeutic Vesicular Nanoreactors with Tumor-Specific Activation and Self-Destruction for Synergistic Tumor Ablation.

Li J, Dirisala A, Ge Z, Wang Y, Yin W, Ke W, Toh K, Xie J, Matsumoto Y, Anraku Y, Osada K, Kataoka K.

Angew Chem Int Ed Engl. 2017 Nov 6;56(45):14025-14030. doi: 10.1002/anie.201706964. Epub 2017 Oct 4.

PMID:
28940903
15.

Pyrazine analogues from wolf urine induced unlearned fear in rats.

Kashiwayanagi M, Miyazono S, Osada K.

Heliyon. 2017 Aug 30;3(8):e00391. doi: 10.1016/j.heliyon.2017.e00391. eCollection 2017 Aug.

16.

Secondary-Structure-Driven Self-Assembly of Reactive Polypept(o)ides: Controlling Size, Shape, and Function of Core Cross-Linked Nanostructures.

Klinker K, Schäfer O, Huesmann D, Bauer T, Capelôa L, Braun L, Stergiou N, Schinnerer M, Dirisala A, Miyata K, Osada K, Cabral H, Kataoka K, Barz M.

Angew Chem Int Ed Engl. 2017 Aug 1;56(32):9608-9613. doi: 10.1002/anie.201702624. Epub 2017 Jul 6.

PMID:
28544124
17.

Methods for the Self-integration of Megamolecular Biopolymers on the Drying Air-LC Interface.

Okeyoshi K, Osada K, Okajima MK, Kaneko T.

J Vis Exp. 2017 Apr 7;(122). doi: 10.3791/55274.

PMID:
28447985
18.
19.

Block Copolymer Micellization as a Protection Strategy for DNA Origami.

Agarwal NP, Matthies M, Gür FN, Osada K, Schmidt TL.

Angew Chem Int Ed Engl. 2017 May 8;56(20):5460-5464. doi: 10.1002/anie.201608873. Epub 2017 Mar 15.

PMID:
28295864
20.

The development of real-time PCR micro device with optical sensor for early detection of cancer.

Kimura Y, Osada K, Inoue Y, Ikeuchi M, Ikuta K.

Conf Proc IEEE Eng Med Biol Soc. 2016 Aug;2016:5737-5740. doi: 10.1109/EMBC.2016.7592030.

PMID:
28269557
21.

Effect of shear stress on structure and function of polyplex micelles from poly(ethylene glycol)-poly(l-lysine) block copolymers as systemic gene delivery carrier.

Takeda KM, Yamasaki Y, Dirisala A, Ikeda S, Tockary TA, Toh K, Osada K, Kataoka K.

Biomaterials. 2017 May;126:31-38. doi: 10.1016/j.biomaterials.2017.02.012. Epub 2017 Feb 20.

PMID:
28254691
22.

Structure-Activity Relationships of Alkylpyrazine Analogs and Fear-Associated Behaviors in Mice.

Osada K, Miyazono S, Kashiwayanagi M.

J Chem Ecol. 2017 Mar;43(3):263-272. doi: 10.1007/s10886-017-0822-3. Epub 2017 Feb 28.

PMID:
28247151
23.

Happy Birthday Kataoka-sensei!

Cabral H, Miyata K, Osada K.

Macromol Biosci. 2017 Jan;17(1). doi: 10.1002/mabi.201600455. No abstract available.

PMID:
28079310
24.

Poly(ethylene glycol) Crowding as Critical Factor To Determine pDNA Packaging Scheme into Polyplex Micelles for Enhanced Gene Expression.

Takeda KM, Osada K, Tockary TA, Dirisala A, Chen Q, Kataoka K.

Biomacromolecules. 2017 Jan 9;18(1):36-43. doi: 10.1021/acs.biomac.6b01247. Epub 2016 Dec 19.

PMID:
27990798
25.

Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting.

Chen Q, Osada K, Ge Z, Uchida S, Tockary TA, Dirisala A, Matsui A, Toh K, Takeda KM, Liu X, Nomoto T, Ishii T, Oba M, Matsumoto Y, Kataoka K.

Biomaterials. 2017 Jan;113:253-265. doi: 10.1016/j.biomaterials.2016.10.042. Epub 2016 Oct 28.

PMID:
27835820
26.

An open-label, long-term, phase III extension trial of duloxetine in Japanese patients with fibromyalgia.

Murakami M, Osada K, Ichibayashi H, Mizuno H, Ochiai T, Ishida M, Alev L, Nishioka K.

Mod Rheumatol. 2017 Jul;27(4):688-695. doi: 10.1080/14397595.2016.1245237. Epub 2016 Oct 31.

PMID:
27796152
27.

Ezetimibe reduced hepatic steatosis induced by dietary oxysterols in nonhuman primates.

Deushi M, Osaka M, Nakano K, Osada K, Egashira K, Yoshida M.

FEBS Open Bio. 2016 Sep 20;6(10):1008-1015. eCollection 2016 Oct.

28.

The Presence of Two Receptor-Binding Proteins Contributes to the Wide Host Range of Staphylococcal Twort-Like Phages.

Takeuchi I, Osada K, Azam AH, Asakawa H, Miyanaga K, Tanji Y.

Appl Environ Microbiol. 2016 Sep 16;82(19):5763-74. doi: 10.1128/AEM.01385-16. Print 2016 Oct 1.

29.

Efficacy of mirtazapine for the treatment of fibromyalgia without concomitant depression: a randomized, double-blind, placebo-controlled phase IIa study in Japan.

Miki K, Murakami M, Oka H, Onozawa K, Yoshida S, Osada K.

Pain. 2016 Sep;157(9):2089-96. doi: 10.1097/j.pain.0000000000000622.

30.

[Pediatric emergency medicine].

Osada K, Sakurai Y, Tamura M.

Nihon Rinsho. 2016 Feb;74(2):274-8. Review. Japanese.

PMID:
26915252
31.

Influence of RNA Strand Rigidity on Polyion Complex Formation with Block Catiomers.

Hayashi K, Chaya H, Fukushima S, Watanabe S, Takemoto H, Osada K, Nishiyama N, Miyata K, Kataoka K.

Macromol Rapid Commun. 2016 Mar;37(6):486-93. doi: 10.1002/marc.201500661. Epub 2016 Jan 14.

PMID:
26765970
32.

Systemic delivery of messenger RNA for the treatment of pancreatic cancer using polyplex nanomicelles with a cholesterol moiety.

Uchida S, Kinoh H, Ishii T, Matsui A, Tockary TA, Takeda KM, Uchida H, Osada K, Itaka K, Kataoka K.

Biomaterials. 2016 Mar;82:221-8. doi: 10.1016/j.biomaterials.2015.12.031. Epub 2015 Dec 31.

PMID:
26763736
33.

"Sizing" Heterogeneous Chemistry in the Conversion of Gaseous Dimethyl Sulfide to Atmospheric Particles.

Enami S, Sakamoto Y, Hara K, Osada K, Hoffmann MR, Colussi AJ.

Environ Sci Technol. 2016 Feb 16;50(4):1834-43. doi: 10.1021/acs.est.5b05337. Epub 2016 Jan 28.

34.

Polyplex Micelles with Double-Protective Compartments of Hydrophilic Shell and Thermoswitchable Palisade of Poly(oxazoline)-Based Block Copolymers for Promoted Gene Transfection.

Osawa S, Osada K, Hiki S, Dirisala A, Ishii T, Kataoka K.

Biomacromolecules. 2016 Jan 11;17(1):354-61. doi: 10.1021/acs.biomac.5b01456. Epub 2015 Dec 28.

35.

Enhanced target recognition of nanoparticles by cocktail PEGylation with chains of varying lengths.

Ishii T, Miyata K, Anraku Y, Naito M, Yi Y, Jinbo T, Takae S, Fukusato Y, Hori M, Osada K, Kataoka K.

Chem Commun (Camb). 2016 Jan 25;52(7):1517-9. doi: 10.1039/c5cc06661a.

PMID:
26658952
36.

The scent of wolves: pyrazine analogs induce avoidance and vigilance behaviors in prey.

Osada K, Miyazono S, Kashiwayanagi M.

Front Neurosci. 2015 Oct 7;9:363. doi: 10.3389/fnins.2015.00363. eCollection 2015. Review.

37.

Rod-to-Globule Transition of pDNA/PEG-Poly(l-Lysine) Polyplex Micelles Induced by a Collapsed Balance Between DNA Rigidity and PEG Crowdedness.

Tockary TA, Osada K, Motoda Y, Hiki S, Chen Q, Takeda KM, Dirisala A, Osawa S, Kataoka K.

Small. 2016 Mar 2;12(9):1193-200. doi: 10.1002/smll.201501815. Epub 2015 Oct 1.

PMID:
26426541
38.

A randomized, double-blind, placebo-controlled phase III trial of duloxetine in Japanese fibromyalgia patients.

Murakami M, Osada K, Mizuno H, Ochiai T, Alev L, Nishioka K.

Arthritis Res Ther. 2015 Aug 22;17:224. doi: 10.1186/s13075-015-0718-y.

39.

Toroidal Packaging of pDNA into Block Ionomer Micelles Exerting Promoted in Vivo Gene Expression.

Li Y, Osada K, Chen Q, Tockary TA, Dirisala A, Takeda KM, Uchida S, Nagata K, Itaka K, Kataoka K.

Biomacromolecules. 2015 Sep 14;16(9):2664-71. doi: 10.1021/acs.biomac.5b00491. Epub 2015 Aug 7.

PMID:
26226080
40.

Psychometric assessment of the Japanese version of the Revised Fibromyalgia Impact Questionnaire: reliability and validity.

Isomura T, Nakamura I, Kawaguchi M, Sato E, Inuzuka K, Osada K, Nishioka K, Hayakawa K.

Int J Rheum Dis. 2017 Sep;20(9):1088-1094. doi: 10.1111/1756-185X.12574. Epub 2015 May 4.

PMID:
25939290
41.

Ternary polyplex micelles with PEG shells and intermediate barrier to complexed DNA cores for efficient systemic gene delivery.

Li J, Chen Q, Zha Z, Li H, Toh K, Dirisala A, Matsumoto Y, Osada K, Kataoka K, Ge Z.

J Control Release. 2015 Jul 10;209:77-87. doi: 10.1016/j.jconrel.2015.04.024. Epub 2015 Apr 23.

PMID:
25912408
42.

Feasibility of a subcutaneously administered block/homo-mixed polyplex micelle as a carrier for DNA vaccination in a mouse tumor model.

Cui L, Osada K, Imaizumi A, Kataoka K, Nakano K.

J Control Release. 2015 May 28;206:220-31. doi: 10.1016/j.jconrel.2015.03.029. Epub 2015 Mar 27.

PMID:
25819159
43.

CEA/CD3-bispecific T cell-engaging (BiTE) antibody-mediated T lymphocyte cytotoxicity maximized by inhibition of both PD1 and PD-L1.

Osada T, Patel SP, Hammond SA, Osada K, Morse MA, Lyerly HK.

Cancer Immunol Immunother. 2015 Jun;64(6):677-88. doi: 10.1007/s00262-015-1671-y. Epub 2015 Mar 6.

PMID:
25742933
44.

A tadpole-shaped gene carrier with distinct phase segregation in a ternary polymeric micelle.

Chen Q, Osada K, Pennisi M, Uchida S, Tockary TA, Dirisala A, Li Y, Takeda KM, Oniyanagi S, Itaka K, Kataoka K.

Soft Matter. 2015 Apr 14;11(14):2718-22. doi: 10.1039/c4sm02850c.

PMID:
25711768
45.

Pyrazine analogs are active components of wolf urine that induce avoidance and fear-related behaviors in deer.

Osada K, Miyazono S, Kashiwayanagi M.

Front Behav Neurosci. 2014 Aug 14;8:276. doi: 10.3389/fnbeh.2014.00276. eCollection 2014.

46.

Impaired mastication reduced newly generated neurons at the accessory olfactory bulb and pheromonal responses in mice.

Utsugi C, Miyazono S, Osada K, Matsuda M, Kashiwayanagi M.

Arch Oral Biol. 2014 Dec;59(12):1272-8. doi: 10.1016/j.archoralbio.2014.07.018. Epub 2014 Aug 2.

PMID:
25150532
47.

In vivo live cell imaging for the quantitative monitoring of lipids by using Raman microspectroscopy.

Hosokawa M, Ando M, Mukai S, Osada K, Yoshino T, Hamaguchi HO, Tanaka T.

Anal Chem. 2014 Aug 19;86(16):8224-30. doi: 10.1021/ac501591d. Epub 2014 Aug 8.

PMID:
25073083
48.

Intraperitoneal administration of a tumor-associated antigen SART3, CD40L, and GM-CSF gene-loaded polyplex micelle elicits a vaccine effect in mouse tumor models.

Furugaki K, Cui L, Kunisawa Y, Osada K, Shinkai K, Tanaka M, Kataoka K, Nakano K.

PLoS One. 2014 Jul 11;9(7):e101854. doi: 10.1371/journal.pone.0101854. eCollection 2014.

49.

Bundled assembly of helical nanostructures in polymeric micelles loaded with platinum drugs enhancing therapeutic efficiency against pancreatic tumor.

Mochida Y, Cabral H, Miura Y, Albertini F, Fukushima S, Osada K, Nishiyama N, Kataoka K.

ACS Nano. 2014 Jul 22;8(7):6724-38. doi: 10.1021/nn500498t. Epub 2014 Jun 13.

PMID:
24927216
50.

Effects of xanthohumol-rich hop extract on the differentiation of preadipocytes.

Kiyofuji A, Yui K, Takahashi K, Osada K.

J Oleo Sci. 2014;63(6):593-7. Epub 2014 May 15.

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