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Items: 36

1.
2.

Phosphorylated Nuclear Receptor CAR Forms a Homodimer To Repress Its Constitutive Activity for Ligand Activation.

Shizu R, Osabe M, Perera L, Moore R, Sueyoshi T, Negishi M.

Mol Cell Biol. 2017 May 2;37(10). pii: e00649-16. doi: 10.1128/MCB.00649-16. Print 2017 May 15.

3.

A hollow-fibre column system to effectively prepare washed platelets.

Tanaka S, Hayashi T, Sugaya S, Osabe M, Ueno Y, Tani Y, Hirayama F.

Vox Sang. 2015 Oct;109(3):239-47. doi: 10.1111/vox.12284. Epub 2015 May 7.

PMID:
25953437
4.

Serum alanine aminotransferase concentration as a predictive factor for the development or regression of fatty liver.

Omagari K, Takamura R, Matsutake S, Ichimura M, Kato S, Morikawa S, Nagaoka S, Osabe M.

J Clin Biochem Nutr. 2011 Nov;49(3):200-6. doi: 10.3164/jcbn.11-27. Epub 2011 Aug 24.

5.
6.

Dephosphorylation of threonine 38 is required for nuclear translocation and activation of human xenobiotic receptor CAR (NR1I3).

Mutoh S, Osabe M, Inoue K, Moore R, Pedersen L, Perera L, Rebolloso Y, Sueyoshi T, Negishi M.

J Biol Chem. 2009 Dec 11;284(50):34785-92. doi: 10.1074/jbc.M109.048108. Epub 2009 Oct 26.

7.

Induction of UGT1A1 and CYP2B6 by an antimitogenic factor in HepG2 cells is mediated through suppression of cyclin-dependent kinase 2 activity: cell cycle-dependent expression.

Sugatani J, Osabe M, Kurosawa M, Kitamura N, Ikari A, Miwa M.

Drug Metab Dispos. 2010 Jan;38(1):177-86. doi: 10.1124/dmd.109.029785.

PMID:
19797611
8.

Predictive factors for the development or regression of Fatty liver in Japanese adults.

Omagari K, Morikawa S, Nagaoka S, Sadakane Y, Sato M, Hamasaki M, Kato S, Masuda J, Osabe M, Kadota T, Sera K.

J Clin Biochem Nutr. 2009 Jul;45(1):56-67. doi: 10.3164/jcbn.08-269. Epub 2009 Jun 30.

9.

Up-regulation of CAR expression through Elk-1 in HepG2 and SW480 cells by serum starvation stress.

Osabe M, Sugatani J, Takemura A, Kurosawa M, Yamazaki Y, Ikari A, Miwa M.

FEBS Lett. 2009 Mar 4;583(5):885-9. doi: 10.1016/j.febslet.2009.01.051. Epub 2009 Feb 6.

10.

Comparison of enzymatically synthesized inulin, resistant maltodextrin and clofibrate effects on biomarkers of metabolic disease in rats fed a high-fat and high-sucrose (cafeteria) diet.

Sugatani J, Osabe M, Wada T, Yamakawa K, Yamazaki Y, Takahashi T, Ikari A, Miwa M.

Eur J Nutr. 2008 Jun;47(4):192-200. doi: 10.1007/s00394-008-0713-z. Epub 2008 Jun 16.

PMID:
18560790
11.

Expression of CAR in SW480 and HepG2 cells during G1 is associated with cell proliferation.

Osabe M, Sugatani J, Takemura A, Yamazaki Y, Ikari A, Kitamura N, Negishi M, Miwa M.

Biochem Biophys Res Commun. 2008 May 16;369(4):1027-33. doi: 10.1016/j.bbrc.2008.02.140. Epub 2008 Mar 10.

PMID:
18331826
12.

Transcriptional regulation of human UGT1A1 gene expression through distal and proximal promoter motifs: implication of defects in the UGT1A1 gene promoter.

Sugatani J, Mizushima K, Osabe M, Yamakawa K, Kakizaki S, Takagi H, Mori M, Ikari A, Miwa M.

Naunyn Schmiedebergs Arch Pharmacol. 2008 Jun;377(4-6):597-605. doi: 10.1007/s00210-007-0226-y. Epub 2008 Jan 3.

PMID:
18172616
15.

A case of double pylorus caused by recurrent gastric ulcers: a long-term endoscopic observation.

Akazawa Y, Mizuta Y, Osabe M, Nakamura T, Morikawa S, Isomoto H, Takeshima F, Kohno S, Murata I.

Dig Dis Sci. 2005 Nov;50(11):2125-8. No abstract available.

PMID:
16240226
16.

Hepatic mucosa-associated lymphoid tissue lymphoma and hepatocellular carcinoma in a patient with hepatitis B virus infection.

Takeshima F, Kunisaki M, Aritomi T, Osabe M, Akama F, Nakasone T, Niino D, Katayama S, Isomoto H, Omagari K, Mizuta Y, Murata I, Kohno S.

J Clin Gastroenterol. 2004 Oct;38(9):823-6.

PMID:
15365414
17.

Polyacetylene glycosides from Pratia nummularia cultures.

Ishimaru K, Osabe M, Yan L, Fujioka T, Mihashi K, Tanaka N.

Phytochemistry. 2003 Feb;62(4):643-6.

PMID:
12560040
18.

A case of acute gastric mucosal lesions associated with Helicobacter heilmannii infection.

Yoshimura M, Isomoto H, Shikuwa S, Osabe M, Matsunaga K, Omagari K, Mizuta Y, Murase K, Murata I, Kohno S.

Helicobacter. 2002 Oct;7(5):322-6.

PMID:
12390213
19.

Primary biliary cirrhosis associated with idiopathic retroperitoneal fibrosis.

Shikuwa- S, Omagari K, Mizuta Y, Murase K, Osabe M, Yoshimura M, Ohfukuji M, Takehara Y, Isomoto H, Ito M, Shimokawa I, Kohno S.

J Gastroenterol. 2000;35(8):646-8.

PMID:
10955606
20.

Esophageal granular cell tumor treated by endoscopic mucosal resection using a ligating device.

Shikuwa S, Matsunaga K, Osabe M, Ofukuji M, Omagari K, Mizuta Y, Takeshima F, Murase K, Otani H, Ito M, Shimokawa I, Fujii M, Kohno S.

Gastrointest Endosc. 1998 Jun;47(6):529-32. No abstract available.

PMID:
9647381
21.

Contribution of alpha 1-acid glycoprotein to species difference in lincosamides-plasma protein binding kinetics.

Son DS, Osabe M, Shimoda M, Kokue E.

J Vet Pharmacol Ther. 1998 Feb;21(1):34-40.

PMID:
9507455
22.

[Successful eradication of H. pylori in an elderly patient with gastric cancer after effective UFT-E therapy].

Matsunaga K, Oofukuji M, Syukuwa S, Osabe M, Takeno Y, Isomoto H, Mizuta Y, Kohno S.

Gan To Kagaku Ryoho. 1997 Dec;24(15):2281-4. Japanese.

PMID:
9422074
23.

Thermostable farnesyl diphosphate synthase of Bacillus stearothermophilus: crystallization and site-directed mutagenesis.

Koyama T, Obata S, Osabe M, Saito K, Takeshita A, Nishino T, Ogura K.

Acta Biochim Pol. 1994;41(3):281-92.

24.

Crystallization and preliminary X-ray diffraction studies of Bacillus stearothermophilus farnesyl diphosphate synthase expressed in Escherichia coli.

Nakane H, Koyama T, Obata S, Osabe M, Takeshita A, Nishino T, Ogura K, Miki K.

J Mol Biol. 1993 Oct 20;233(4):787-8.

PMID:
8411181
25.

Thermostable farnesyl diphosphate synthase of Bacillus stearothermophilus: molecular cloning, sequence determination, overproduction, and purification.

Koyama T, Obata S, Osabe M, Takeshita A, Yokoyama K, Uchida M, Nishino T, Ogura K.

J Biochem. 1993 Mar;113(3):355-63.

26.

[Effect of tranilast (N-5) on cellular immunity--delayed type hypersensitivity].

Osabe M.

Arerugi. 1991 Mar;40(3 Pt 1):231-8. Japanese.

PMID:
1711310
27.

[Ulcerative colitis developing multiple colorectal carcinomas--report of a case with review of literature].

Murata I, Makiyama K, Tanaka T, Senju M, Osabe M, Funatsu S, Itsuno M, Imanishi T, Hara K, Eguchi K, et al.

Nihon Shokakibyo Gakkai Zasshi. 1988 Jan;85(1):107-11. Review. Japanese. No abstract available.

PMID:
3286930
28.

Characterization of directly acting mutagens produced from N-nitroso-N-(formylmethyl)alkylamines: their possible involvement in the carcinogenesis of N-nitrosamines having a 2-hydroxyethyl group.

Suzuki E, Osabe M, Mochizuki M, Wakabayashi Y, Okada M.

Chem Pharm Bull (Tokyo). 1987 Oct;35(10):4022-30. No abstract available.

PMID:
3435935
29.

Urinary metabolites of N-nitrosodibutylamine and N-nitrodibutylamine in the rat: identification of N-acetyl-S-alkyl-L-cysteines.

Suzuki E, Osabe M, Okada M, Ishizaka T, Suzuki T.

Jpn J Cancer Res. 1987 Apr;78(4):382-5.

PMID:
3108218
30.

[Mast cells, IgE containing cells and tissue histamine contents in normal mucosa of each part of the large intestine].

Senjuh M, Makiyama K, Osabe M, Itsuno M, Kitsukawa K, Murata I, Tanaka Y, Hara K.

Nihon Shokakibyo Gakkai Zasshi. 1987 Feb;84(2):216-20. Japanese. No abstract available.

PMID:
3586370
31.

Urinary metabolites of N-nitrosodibutylamine in the rat: identification of N-acetyl-S-butyl-L-cysteine derivatives.

Suzuki E, Osabe M, Okada M, Ishizaka T, Suzuki T.

IARC Sci Publ. 1987;(84):153-5.

PMID:
3679356
32.

Directly-acting mutagens formed from N-nitroso-N-(formylmethyl)alkylamines.

Suzuki E, Osabe M, Mochizuki M, Okada M.

IARC Sci Publ. 1987;(84):100-3.

PMID:
3315995
33.

In vitro metabolism of N-nitrodialkylamines.

Suzuki E, Mochizuki M, Sekiguchi N, Osabe M, Okada M.

Jpn J Cancer Res. 1985 Jan;76(1):28-36.

PMID:
3918908
34.

Mutagenicity of alpha-hydroxy N-nitrosamines in V79 Chinese hamster cells.

Mochizuki M, Osabe M, Anjo T, Suzuki E, Okada M.

J Cancer Res Clin Oncol. 1984;108(3):290-5.

PMID:
6511803
35.

Mutagenicity of alpha-hydroxy N-nitrosamines in V79 Chinese hamster cells.

Mochizuki M, Osabe M, Anjo T, Takeda K, Suzuki E, Okada M.

IARC Sci Publ. 1984;(57):715-9.

PMID:
6398304
36.

Effect of metal cations on misincorporation by E. coli DNA polymerases.

Miyaki M, Murata I, Osabe M, Ono T.

Biochem Biophys Res Commun. 1977 Aug 8;77(3):854-60. No abstract available.

PMID:
332171

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