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Items: 1 to 50 of 109

1.

Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy.

Stafford WC, Peng X, Olofsson MH, Zhang X, Luci DK, Lu L, Cheng Q, Trésaugues L, Dexheimer TS, Coussens NP, Augsten M, Ahlzén HM, Orwar O, Östman A, Stone-Elander S, Maloney DJ, Jadhav A, Simeonov A, Linder S, Arnér ESJ.

Sci Transl Med. 2018 Feb 14;10(428). pii: eaaf7444. doi: 10.1126/scitranslmed.aaf7444.

PMID:
29444979
2.

Spatial characterization of a multifunctional pipette for drug delivery in hippocampal brain slices.

Ahemaiti A, Wigström H, Ainla A, Jeffries GD, Orwar O, Jesorka A, Jardemark K.

J Neurosci Methods. 2015 Feb 15;241:132-6. doi: 10.1016/j.jneumeth.2014.12.017. Epub 2014 Dec 30.

3.

Probing structure and function of ion channels using limited proteolysis and microfluidics.

Trkulja CL, Jansson ET, Jardemark K, Orwar O.

J Am Chem Soc. 2014 Oct 22;136(42):14875-82. doi: 10.1021/ja507285w. Epub 2014 Oct 10.

PMID:
25254316
4.

Probing enzymatic activity inside single cells.

Olofsson J, Xu S, Jeffries GD, Jesorka A, Bridle H, Isaksson I, Weber SG, Orwar O.

Anal Chem. 2013 Nov 5;85(21):10126-33. doi: 10.1021/ac4013122. Epub 2013 Oct 23.

5.

A multifunctional pipette for localized drug administration to brain slices.

Ahemaiti A, Ainla A, Jeffries GD, Wigström H, Orwar O, Jesorka A, Jardemark K.

J Neurosci Methods. 2013 Oct 15;219(2):292-6. doi: 10.1016/j.jneumeth.2013.08.012. Epub 2013 Aug 19.

6.

Effect of cholesterol depletion on the pore dilation of TRPV1.

Jansson ET, Trkulja CL, Ahemaiti A, Millingen M, Jeffries GD, Jardemark K, Orwar O.

Mol Pain. 2013 Jan 2;9:1. doi: 10.1186/1744-8069-9-1.

7.

Kinetics of diffusion-mediated DNA hybridization in lipid monolayer films determined by single-molecule fluorescence spectroscopy.

Hannestad JK, Brune R, Czolkos I, Jesorka A, El-Sagheer AH, Brown T, Albinsson B, Orwar O.

ACS Nano. 2013 Jan 22;7(1):308-15. doi: 10.1021/nn304010p. Epub 2012 Dec 20.

PMID:
23215045
8.

Microfluidic flow cell for sequential digestion of immobilized proteoliposomes.

Jansson ET, Trkulja CL, Olofsson J, Millingen M, Wikström J, Jesorka A, Karlsson A, Karlsson R, Davidson M, Orwar O.

Anal Chem. 2012 Jul 3;84(13):5582-8. doi: 10.1021/ac300519q. Epub 2012 Jun 13.

PMID:
22656064
9.

Radial sizing of lipid nanotubes using membrane displacement analysis.

Stepanyants N, Jeffries GD, Orwar O, Jesorka A.

Nano Lett. 2012 Mar 14;12(3):1372-8. doi: 10.1021/nl203983e. Epub 2012 Feb 24.

10.

A multifunctional pipette.

Ainla A, Jeffries GD, Brune R, Orwar O, Jesorka A.

Lab Chip. 2012 Apr 7;12(7):1255-61. doi: 10.1039/c2lc20906c. Epub 2012 Jan 17.

11.

High-resolution micropatterned Teflon AF substrates for biocompatible nanofluidic devices.

Czolkos I, Hakonen B, Orwar O, Jesorka A.

Langmuir. 2012 Feb 14;28(6):3200-5. doi: 10.1021/la2044784. Epub 2012 Jan 31.

PMID:
22204476
12.

Nanofluidics: Neither shaken nor stirred.

Jesorka A, Orwar O.

Nat Nanotechnol. 2011 Dec 28;7(1):6-7. doi: 10.1038/nnano.2011.236. No abstract available.

PMID:
22203312
13.

Membrane protrusion coarsening and nanotubulation within giant unilamellar vesicles.

Węgrzyn I, Jeffries GD, Nagel B, Katterle M, Gerrard SR, Brown T, Orwar O, Jesorka A.

J Am Chem Soc. 2011 Nov 16;133(45):18046-9. doi: 10.1021/ja207536a. Epub 2011 Oct 21.

PMID:
21978148
14.

Generation of phospholipid vesicle-nanotube networks and transport of molecules therein.

Jesorka A, Stepanyants N, Zhang H, Ortmen B, Hakonen B, Orwar O.

Nat Protoc. 2011 Jun;6(6):791-805. doi: 10.1038/nprot.2011.321. Epub 2011 May 19.

PMID:
21637199
15.

Fractal avalanche ruptures in biological membranes.

Gözen I, Dommersnes P, Czolkos I, Jesorka A, Lobovkina T, Orwar O.

Nat Mater. 2010 Nov;9(11):908-12. doi: 10.1038/nmat2854. Epub 2010 Oct 10.

PMID:
20935656
16.

Single-cell electroporation.

Wang M, Orwar O, Olofsson J, Weber SG.

Anal Bioanal Chem. 2010 Aug;397(8):3235-48. doi: 10.1007/s00216-010-3744-2. Epub 2010 May 23. Review.

PMID:
20496058
17.

A microfluidic pipette for single-cell pharmacology.

Ainla A, Jansson ET, Stepanyants N, Orwar O, Jesorka A.

Anal Chem. 2010 Jun 1;82(11):4529-36. doi: 10.1021/ac100480f.

PMID:
20443547
18.

A method for heat-stimulated compression of poly(N-isopropyl acrylamide) hydrogels inside single giant unilamellar vesicles.

Osinkina L, Markström M, Orwar O, Jesorka A.

Langmuir. 2010 Jan 5;26(1):1-4. doi: 10.1021/la9041524.

PMID:
19916531
19.

Chapter 15 - Complex nanotube-liposome networks.

Jesorka A, Orwar O.

Methods Enzymol. 2009;464:309-25. doi: 10.1016/S0076-6879(09)64015-5.

PMID:
19903561
20.

Control of the release of freely diffusing molecules in single-cell electroporation.

Agarwal A, Wang M, Olofsson J, Orwar O, Weber SG.

Anal Chem. 2009 Oct 1;81(19):8001-8. doi: 10.1021/ac9010292.

21.

Platform for controlled supramolecular nanoassembly.

Czolkos I, Hannestad JK, Jesorka A, Kumar R, Brown T, Albinsson B, Orwar O.

Nano Lett. 2009 Jun;9(6):2482-6. doi: 10.1021/nl901254f. Erratum in: Nano Lett. 2009 Oct;9(10):3669-70.

PMID:
19507892
22.

A microfluidic diluter based on pulse width flow modulation.

Ainla A, Gözen I, Orwar O, Jesorka A.

Anal Chem. 2009 Jul 1;81(13):5549-56. doi: 10.1021/ac9010028.

PMID:
19476370
23.

A giant liposome for single-molecule observation of conformational changes in membrane proteins.

Onoue Y, Suzuki T, Davidson M, Karlsson M, Orwar O, Yoshida M, Kinosita K Jr.

Biochim Biophys Acta. 2009 Jun;1788(6):1332-40. doi: 10.1016/j.bbamem.2009.01.015. Epub 2009 Feb 3.

24.

Single-cell transfection by electroporation using an electrolyte/plasmid-filled capillary.

Wang M, Orwar O, Weber SG.

Anal Chem. 2009 May 15;81(10):4060-7. doi: 10.1021/ac900265f.

25.

Direct access and control of the intracellular solution environment in single cells.

Olofsson J, Bridle H, Jesorka A, Isaksson I, Weber S, Orwar O.

Anal Chem. 2009 Mar 1;81(5):1810-8. doi: 10.1021/ac802081m.

26.

Proteomic analysis of plasma membrane vesicles.

Bauer B, Davidson M, Orwar O.

Angew Chem Int Ed Engl. 2009;48(9):1656-9. doi: 10.1002/anie.200803898.

PMID:
19156792
27.

Controlling chemistry by geometry in nanoscale systems.

Lizana L, Konkoli Z, Bauer B, Jesorka A, Orwar O.

Annu Rev Phys Chem. 2009;60:449-68. doi: 10.1146/annurev.physchem.040808.090255. Review.

PMID:
18999989
28.

Liposomes: technologies and analytical applications.

Jesorka A, Orwar O.

Annu Rev Anal Chem (Palo Alto Calif). 2008;1:801-32. doi: 10.1146/annurev.anchem.1.031207.112747. Review.

PMID:
20636098
29.

Shape optimization in lipid nanotube networks.

Lobovkina T, Dommersnes PG, Tiourine S, Joanny JF, Orwar O.

Eur Phys J E Soft Matter. 2008 Jul;26(3):295-300. doi: 10.1140/epje/i2007-10325-x. Epub 2008 May 26.

PMID:
18500443
30.

Thermoactuated diffusion control in soft matter nanofluidic devices.

Markström M, Lizana L, Orwar O, Jesorka A.

Langmuir. 2008 May 6;24(9):5166-71. doi: 10.1021/la7035967. Epub 2008 Apr 8.

PMID:
18393556
31.

Controlling the rates of biochemical reactions and signaling networks by shape and volume changes.

Lizana L, Bauer B, Orwar O.

Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4099-104. doi: 10.1073/pnas.0709932105. Epub 2008 Mar 12.

32.

Controlled release of chol-TEG-DNA from Nano- and micropatterned SU-8 surfaces by a spreading lipid film.

Erkan Y, Halma K, Czolkos I, Jesorka A, Dommersnes P, Kumar R, Brown T, Orwar O.

Nano Lett. 2008 Jan;8(1):227-31. Epub 2007 Dec 11.

PMID:
18069872
33.

Ligand-specific temperature-dependent shifts in EC50 values for the GABAA receptor.

Millingen M, Bridle H, Jesorka A, Lincoln P, Orwar O.

Anal Chem. 2008 Jan 1;80(1):340-3. Epub 2007 Dec 5.

PMID:
18052252
34.

Automated control of local solution environments in open-volume microfluidics.

Bridle H, Olofsson J, Jesorka A, Orwar O.

Anal Chem. 2007 Dec 15;79(24):9286-93. Epub 2007 Nov 15.

PMID:
18001008
35.

Controlled formation and mixing of two-dimensional fluids.

Czolkos I, Erkan Y, Dommersnes P, Jesorka A, Orwar O.

Nano Lett. 2007 Jul;7(7):1980-4. Epub 2007 Jun 6. Review.

PMID:
17550298
36.

Electrophoretic transport of latex particles in lipid nanotubes.

Tokarz M, Hakonen B, Dommersnes P, Orwar O, Akerman B.

Langmuir. 2007 Jul 3;23(14):7652-8. Epub 2007 Jun 5.

PMID:
17547424
37.

Scanning electroporation of selected areas of adherent cell cultures.

Olofsson J, Levin M, Strömberg A, Weber SG, Ryttsén F, Orwar O.

Anal Chem. 2007 Jun 15;79(12):4410-8. Epub 2007 May 19.

PMID:
17511419
38.

Tunable filtering of chemical signals in a simple nanoscale reaction-diffusion network.

Lizana L, Konkoli Z, Orwar O.

J Phys Chem B. 2007 Jun 7;111(22):6214-9. Epub 2007 May 12.

PMID:
17497911
39.

Effect of cell size and shape on single-cell electroporation.

Agarwal A, Zudans I, Weber EA, Olofsson J, Orwar O, Weber SG.

Anal Chem. 2007 May 15;79(10):3589-96. Epub 2007 Apr 20.

40.

Direct immobilization of cholesteryl-TEG-modified oligonucleotides onto hydrophobic SU-8 surfaces.

Erkan Y, Czolkos I, Jesorka A, Wilhelmsson LM, Orwar O.

Langmuir. 2007 May 8;23(10):5259-63. Epub 2007 Apr 14.

PMID:
17432889
41.
42.

Numerical calculations of single-cell electroporation with an electrolyte-filled capillary.

Zudans I, Agarwal A, Orwar O, Weber SG.

Biophys J. 2007 May 15;92(10):3696-705. Epub 2007 Mar 9.

43.
44.

Zipper dynamics of surfactant nanotube Y junctions.

Lobovkina T, Dommersnes P, Joanny JF, Hurtig J, Orwar O.

Phys Rev Lett. 2006 Nov 3;97(18):188105. Epub 2006 Nov 3. Erratum in: Phys Rev Lett. 2006 Nov 17;97(20):209901.

PMID:
17155584
45.

Controlling desensitized states in ligand-receptor interaction studies with cyclic scanning patch-clamp protocols.

Granfeldt D, Sinclair J, Millingen M, Farre C, Lincoln P, Orwar O.

Anal Chem. 2006 Dec 1;78(23):7947-53.

PMID:
17134126
46.

Direct reconstitution of plasma membrane lipids and proteins in nanotube-vesicle networks.

Bauer B, Davidson M, Orwar O.

Langmuir. 2006 Oct 24;22(22):9329-32.

PMID:
17042549
47.

Chemical analysis in nanoscale surfactant networks.

Karlsson R, Karlsson A, Ewing A, Dommersnes P, Joanny JF, Jesorka A, Orwar O.

Anal Chem. 2006 Sep 1;78(17):5961-8. No abstract available.

PMID:
16995281
48.

Electrophoretic transport in surfactant nanotube networks wired on microfabricated substrates.

Hurtig J, Gustafsson B, Tokarz M, Orwar O.

Anal Chem. 2006 Aug 1;78(15):5281-8.

PMID:
16878860
49.

Controlled hydrogel formation in the internal compartment of giant unilamellar vesicles.

Jesorka A, Markström M, Karlsson M, Orwar O.

J Phys Chem B. 2005 Aug 11;109(31):14759-63.

PMID:
16852864
50.

Controlled initiation of enzymatic reactions in micrometer-sized biomimetic compartments.

Karlsson A, Sott K, Markström M, Davidson M, Konkoli Z, Orwar O.

J Phys Chem B. 2005 Feb 3;109(4):1609-17.

PMID:
16851132

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