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Items: 29

1.

Cell cycle regulators control mesoderm specification in human pluripotent stem cells.

Yiangou L, Grandy RA, Osnato A, Ortmann D, Sinha S, Vallier L.

J Biol Chem. 2019 Sep 12. pii: jbc.RA119.008251. doi: 10.1074/jbc.RA119.008251. [Epub ahead of print]

2.

Method to Synchronize Cell Cycle of Human Pluripotent Stem Cells without Affecting Their Fundamental Characteristics.

Yiangou L, Grandy RA, Morell CM, Tomaz RA, Osnato A, Kadiwala J, Muraro D, Garcia-Bernardo J, Nakanoh S, Bernard WG, Ortmann D, McCarthy DJ, Simonic I, Sinha S, Vallier L.

Stem Cell Reports. 2019 Jan 8;12(1):165-179. doi: 10.1016/j.stemcr.2018.11.020. Epub 2018 Dec 27.

3.

Human axial progenitors generate trunk neural crest cells in vitro.

Frith TJ, Granata I, Wind M, Stout E, Thompson O, Neumann K, Stavish D, Heath PR, Ortmann D, Hackland JO, Anastassiadis K, Gouti M, Briscoe J, Wilson V, Johnson SL, Placzek M, Guarracino MR, Andrews PW, Tsakiridis A.

Elife. 2018 Aug 10;7. pii: e35786. doi: 10.7554/eLife.35786.

4.

Conditional Manipulation of Gene Function in Human Cells with Optimized Inducible shRNA.

Bertero A, Yiangou L, Brown S, Ortmann D, Pawlowski M, Vallier L.

Curr Protoc Stem Cell Biol. 2018 Feb 28;44:5C.4.1-5C.4.48. doi: 10.1002/cpsc.45.

PMID:
29512130
5.

The SMAD2/3 interactome reveals that TGFβ controls m6A mRNA methylation in pluripotency.

Bertero A, Brown S, Madrigal P, Osnato A, Ortmann D, Yiangou L, Kadiwala J, Hubner NC, de Los Mozos IR, Sadée C, Lenaerts AS, Nakanoh S, Grandy R, Farnell E, Ule J, Stunnenberg HG, Mendjan S, Vallier L.

Nature. 2018 Mar 8;555(7695):256-259. doi: 10.1038/nature25784. Epub 2018 Feb 28.

6.

A novel piperidine identified by stem cell-based screening attenuates pulmonary arterial hypertension by regulating BMP2 and PTGS2 levels.

Xing Y, Zhao S, Wei Q, Gong S, Zhao X, Zhou F, Ai-Lamki R, Ortmann D, Du M, Pedersen R, Shang G, Si S, Morrell NW, Yang J.

Eur Respir J. 2018 Apr 4;51(4). pii: 1702229. doi: 10.1183/13993003.02229-2017. Print 2018 Apr.

PMID:
29449428
7.

Variability of human pluripotent stem cell lines.

Ortmann D, Vallier L.

Curr Opin Genet Dev. 2017 Oct;46:179-185. doi: 10.1016/j.gde.2017.07.004. Epub 2017 Aug 24. Review.

PMID:
28843810
8.

Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids.

Sampaziotis F, Justin AW, Tysoe OC, Sawiak S, Godfrey EM, Upponi SS, Gieseck RL 3rd, de Brito MC, Berntsen NL, Gómez-Vázquez MJ, Ortmann D, Yiangou L, Ross A, Bargehr J, Bertero A, Zonneveld MCF, Pedersen MT, Pawlowski M, Valestrand L, Madrigal P, Georgakopoulos N, Pirmadjid N, Skeldon GM, Casey J, Shu W, Materek PM, Snijders KE, Brown SE, Rimland CA, Simonic I, Davies SE, Jensen KB, Zilbauer M, Gelson WTH, Alexander GJ, Sinha S, Hannan NRF, Wynn TA, Karlsen TH, Melum E, Markaki AE, Saeb-Parsy K, Vallier L.

Nat Med. 2017 Aug;23(8):954-963. doi: 10.1038/nm.4360. Epub 2017 Jul 3.

9.

Inducible and Deterministic Forward Programming of Human Pluripotent Stem Cells into Neurons, Skeletal Myocytes, and Oligodendrocytes.

Pawlowski M, Ortmann D, Bertero A, Tavares JM, Pedersen RA, Vallier L, Kotter MRN.

Stem Cell Reports. 2017 Apr 11;8(4):803-812. doi: 10.1016/j.stemcr.2017.02.016. Epub 2017 Mar 23.

10.

Optimized inducible shRNA and CRISPR/Cas9 platforms for in vitro studies of human development using hPSCs.

Bertero A, Pawlowski M, Ortmann D, Snijders K, Yiangou L, Cardoso de Brito M, Brown S, Bernard WG, Cooper JD, Giacomelli E, Gambardella L, Hannan NR, Iyer D, Sampaziotis F, Serrano F, Zonneveld MC, Sinha S, Kotter M, Vallier L.

Development. 2016 Dec 1;143(23):4405-4418.

11.

Brachyury and SMAD signalling collaboratively orchestrate distinct mesoderm and endoderm gene regulatory networks in differentiating human embryonic stem cells.

Faial T, Bernardo AS, Mendjan S, Diamanti E, Ortmann D, Gentsch GE, Mascetti VL, Trotter MW, Smith JC, Pedersen RA.

Development. 2015 Jun 15;142(12):2121-35. doi: 10.1242/dev.117838. Epub 2015 May 26.

12.

NANOG and CDX2 pattern distinct subtypes of human mesoderm during exit from pluripotency.

Mendjan S, Mascetti VL, Ortmann D, Ortiz M, Karjosukarso DW, Ng Y, Moreau T, Pedersen RA.

Cell Stem Cell. 2014 Sep 4;15(3):310-325. doi: 10.1016/j.stem.2014.06.006. Epub 2014 Jul 18.

13.

BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages.

Bernardo AS, Faial T, Gardner L, Niakan KK, Ortmann D, Senner CE, Callery EM, Trotter MW, Hemberger M, Smith JC, Bardwell L, Moffett A, Pedersen RA.

Cell Stem Cell. 2011 Aug 5;9(2):144-55. doi: 10.1016/j.stem.2011.06.015.

14.

Methods for embryoid body formation: the microwell approach.

Spelke DP, Ortmann D, Khademhosseini A, Ferreira L, Karp JM.

Methods Mol Biol. 2011;690:151-62. doi: 10.1007/978-1-60761-962-8_10.

PMID:
21042991
15.

Microwell-mediated control of embryoid body size regulates embryonic stem cell fate via differential expression of WNT5a and WNT11.

Hwang YS, Chung BG, Ortmann D, Hattori N, Moeller HC, Khademhosseini A.

Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):16978-83. doi: 10.1073/pnas.0905550106. Epub 2009 Sep 23.

16.

A hollow sphere soft lithography approach for long-term hanging drop methods.

Lee WG, Ortmann D, Hancock MJ, Bae H, Khademhosseini A.

Tissue Eng Part C Methods. 2010 Apr;16(2):249-59. doi: 10.1089/ten.TEC.2009.0248.

17.

Development of a highly selective and efficient catalyst for 1,3-butadiene dimerization.

Harkal S, Jackstell R, Nierlich F, Ortmann D, Beller M.

Org Lett. 2005 Feb 17;7(4):541-4.

PMID:
15704889
18.
19.

Induction of anti-hepatitis B virus immune responses through DNA immunization.

Geissler M, Weth R, Grimm CF, Ortmann D, Blum HE.

Methods Mol Med. 2004;96:43-54. No abstract available.

PMID:
14762258
20.

Steroidogenic acute regulatory (StAR)-directed immunotherapy protects against tumor growth of StAR-expressing Sp2-0 cells in a rodent adrenocortical carcinoma model.

Ortmann D, Hausmann J, Beuschlein F, Schmenger K, Stahl M, Geissler M, Reincke M.

Endocrinology. 2004 Apr;145(4):1760-6. Epub 2004 Jan 8.

PMID:
14715709
21.

Immunotherapy: new strategies for the treatment of adrenocortical carcinoma.

Schott M, Reincke M, Ortmann D, Bornstein SR.

Horm Metab Res. 2003 Jul;35(7):451-3. Review. No abstract available.

PMID:
12931278
22.

Growth suppression of the hepatocellular carcinoma cell line Hepa1-6 by an activatable interferon regulatory factor-1 in mice.

Kröger A, Ortmann D, Krohne TU, Mohr L, Blum HE, Hauser H, Geissler M.

Cancer Res. 2001 Mar 15;61(6):2609-17.

23.

Mouse alpha-fetoprotein-specific DNA-based immunotherapy of hepatocellular carcinoma leads to tumor regression in mice.

Grimm CF, Ortmann D, Mohr L, Michalak S, Krohne TU, Meckel S, Eisele S, Encke J, Blum HE, Geissler M.

Gastroenterology. 2000 Oct;119(4):1104-12.

PMID:
11040197
24.

Intracellular retention of hepatitis B virus surface proteins reduces interleukin-2 augmentation after genetic immunizations.

Geissler M, Bruss V, Michalak S, Hockenjos B, Ortmann D, Offensperger WB, Wands JR, Blum HE.

J Virol. 1999 May;73(5):4284-92.

25.

Adenovirus death protein, a transmembrane protein encoded in the E3 region, is palmitoylated at the cytoplasmic tail.

Hausmann J, Ortmann D, Witt E, Veit M, Seidel W.

Virology. 1998 May 10;244(2):343-51.

26.

Case study: nursing diagnosis in crosscultural settings.

Levine MA, Ortmann D.

Nurs Diagn. 1994 Oct-Dec;5(4):158, 172-3. No abstract available.

PMID:
7826719
27.
28.

Processing of viral glycoproteins by the subtilisin-like endoprotease furin and its inhibition by specific peptidylchloroalkylketones.

Garten W, Hallenberger S, Ortmann D, Schäfer W, Vey M, Angliker H, Shaw E, Klenk HD.

Biochimie. 1994;76(3-4):217-25. Review.

PMID:
7819326
29.

Structure and assembly of hemagglutinin mutants of fowl plague virus with impaired surface transport.

Garten W, Will C, Buckard K, Kuroda K, Ortmann D, Munk K, Scholtissek C, Schnittler H, Drenckhahn D, Klenk HD.

J Virol. 1992 Mar;66(3):1495-505.

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