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Items: 28

1.

Microglia morphology and proinflammatory signaling in the nucleus accumbens during nicotine withdrawal.

Adeluyi A, Guerin L, Fisher ML, Galloway A, Cole RD, Chan SSL, Wyatt MD, Davis SW, Freeman LR, Ortinski PI, Turner JR.

Sci Adv. 2019 Oct 9;5(10):eaax7031. doi: 10.1126/sciadv.aax7031. eCollection 2019 Oct.

2.

Altered gating of Kv1.4 in the nucleus accumbens suppresses motivation for reward.

O'Donovan B, Adeluyi A, Anderson EL, Cole RD, Turner JR, Ortinski PI.

Elife. 2019 Sep 5;8. pii: e47870. doi: 10.7554/eLife.47870.

3.

Identification of Novel Protein Targets of Dimethyl Fumarate Modification in Neurons and Astrocytes Reveals Actions Independent of Nrf2 Stabilization.

Piroli GG, Manuel AM, Patel T, Walla MD, Shi L, Lanci SA, Wang J, Galloway A, Ortinski PI, Smith DS, Frizzell N.

Mol Cell Proteomics. 2019 Mar;18(3):504-519. doi: 10.1074/mcp.RA118.000922. Epub 2018 Dec 26.

PMID:
30587509
4.

Dopamine Triggers CTCF-Dependent Morphological and Genomic Remodeling of Astrocytes.

Galloway A, Adeluyi A, O'Donovan B, Fisher ML, Rao CN, Critchfield P, Sajish M, Turner JR, Ortinski PI.

J Neurosci. 2018 May 23;38(21):4846-4858. doi: 10.1523/JNEUROSCI.3349-17.2018. Epub 2018 Apr 30.

5.

Activation of glucagon-like peptide-1 receptors in the nucleus accumbens attenuates cocaine seeking in rats.

Hernandez NS, O'Donovan B, Ortinski PI, Schmidt HD.

Addict Biol. 2019 Mar;24(2):170-181. doi: 10.1111/adb.12583. Epub 2017 Dec 11.

PMID:
29226617
6.

Neuregulin 3 Signaling Mediates Nicotine-Dependent Synaptic Plasticity in the Orbitofrontal Cortex and Cognition.

Zhou L, Fisher ML, Cole RD, Gould TJ, Parikh V, Ortinski PI, Turner JR.

Neuropsychopharmacology. 2018 May;43(6):1343-1354. doi: 10.1038/npp.2017.278. Epub 2017 Nov 7.

7.

Integrase-Deficient Lentiviral Vector as an All-in-One Platform for Highly Efficient CRISPR/Cas9-Mediated Gene Editing.

Ortinski PI, O'Donovan B, Dong X, Kantor B.

Mol Ther Methods Clin Dev. 2017 Apr 19;5:153-164. doi: 10.1016/j.omtm.2017.04.002. eCollection 2017 Jun 16.

8.

Behavioral History of Withdrawal Influences Regulation of Cocaine Seeking by Glutamate Re-Uptake.

Zhou L, Andersen H, Arreola AC, Turner JR, Ortinski PI.

PLoS One. 2016 Sep 29;11(9):e0163784. doi: 10.1371/journal.pone.0163784. eCollection 2016.

9.

A Critical Role for the GluA1 Accessory Protein, SAP97, in Cocaine Seeking.

White SL, Ortinski PI, Friedman SH, Zhang L, Neve RL, Kalb RG, Schmidt HD, Pierce RC.

Neuropsychopharmacology. 2016 Feb;41(3):736-50. doi: 10.1038/npp.2015.199. Epub 2015 Jul 7.

10.

Cocaine-seeking is associated with PKC-dependent reduction of excitatory signaling in accumbens shell D2 dopamine receptor-expressing neurons.

Ortinski PI, Briand LA, Pierce RC, Schmidt HD.

Neuropharmacology. 2015 May;92:80-9. doi: 10.1016/j.neuropharm.2015.01.002. Epub 2015 Jan 14.

11.

Pyramidal cell selective ablation of N-methyl-D-aspartate receptor 1 causes increase in cellular and network excitability.

Tatard-Leitman VM, Jutzeler CR, Suh J, Saunders JA, Billingslea EN, Morita S, White R, Featherstone RE, Ray R, Ortinski PI, Banerjee A, Gandal MJ, Lin R, Alexandrescu A, Liang Y, Gur RE, Borgmann-Winter KE, Carlson GC, Hahn CG, Siegel SJ.

Biol Psychiatry. 2015 Mar 15;77(6):556-68. doi: 10.1016/j.biopsych.2014.06.026. Epub 2014 Jul 18.

12.

Glucagon-like peptide-1 receptor activation in the nucleus accumbens core suppresses feeding by increasing glutamatergic AMPA/kainate signaling.

Mietlicki-Baase EG, Ortinski PI, Reiner DJ, Sinon CG, McCutcheon JE, Pierce RC, Roitman MF, Hayes MR.

J Neurosci. 2014 May 14;34(20):6985-92. doi: 10.1523/JNEUROSCI.0115-14.2014.

13.

Parvalbumin cell ablation of NMDA-R1 causes increased resting network excitability with associated social and self-care deficits.

Billingslea EN, Tatard-Leitman VM, Anguiano J, Jutzeler CR, Suh J, Saunders JA, Morita S, Featherstone RE, Ortinski PI, Gandal MJ, Lin R, Liang Y, Gur RE, Carlson GC, Hahn CG, Siegel SJ.

Neuropsychopharmacology. 2014 Jun;39(7):1603-13. doi: 10.1038/npp.2014.7. Epub 2014 Feb 14.

14.

Cocaine-induced changes in NMDA receptor signaling.

Ortinski PI.

Mol Neurobiol. 2014 Oct;50(2):494-506. doi: 10.1007/s12035-014-8636-6. Epub 2014 Jan 21. Review.

15.

Disruption of glutamate receptor-interacting protein in nucleus accumbens enhances vulnerability to cocaine relapse.

Briand LA, Kimmey BA, Ortinski PI, Huganir RL, Pierce RC.

Neuropsychopharmacology. 2014 Feb;39(3):759-69. doi: 10.1038/npp.2013.265. Epub 2013 Oct 15.

16.

The food intake-suppressive effects of glucagon-like peptide-1 receptor signaling in the ventral tegmental area are mediated by AMPA/kainate receptors.

Mietlicki-Baase EG, Ortinski PI, Rupprecht LE, Olivos DR, Alhadeff AL, Pierce RC, Hayes MR.

Am J Physiol Endocrinol Metab. 2013 Dec 1;305(11):E1367-74. doi: 10.1152/ajpendo.00413.2013. Epub 2013 Oct 8.

17.

Extrasynaptic targeting of NMDA receptors following D1 dopamine receptor activation and cocaine self-administration.

Ortinski PI, Turner JR, Pierce RC.

J Neurosci. 2013 May 29;33(22):9451-61. doi: 10.1523/JNEUROSCI.5730-12.2013.

18.

GABAB-mediated rescue of altered excitatory-inhibitory balance, gamma synchrony and behavioral deficits following constitutive NMDAR-hypofunction.

Gandal MJ, Sisti J, Klook K, Ortinski PI, Leitman V, Liang Y, Thieu T, Anderson R, Pierce RC, Jonak G, Gur RE, Carlson G, Siegel SJ.

Transl Psychiatry. 2012 Jul 17;2:e142. doi: 10.1038/tp.2012.69.

19.

Deterministic and stochastic neuronal contributions to distinct synchronous CA3 network bursts.

Takano H, McCartney M, Ortinski PI, Yue C, Putt ME, Coulter DA.

J Neurosci. 2012 Apr 4;32(14):4743-54. doi: 10.1523/JNEUROSCI.4277-11.2012.

20.

Temporally dependent changes in cocaine-induced synaptic plasticity in the nucleus accumbens shell are reversed by D1-like dopamine receptor stimulation.

Ortinski PI, Vassoler FM, Carlson GC, Pierce RC.

Neuropsychopharmacology. 2012 Jun;37(7):1671-82. doi: 10.1038/npp.2012.12. Epub 2012 Mar 14.

21.

Cerebellar nicotinic cholinergic receptors are intrinsic to the cerebellum: implications for diverse functional roles.

Turner JR, Ortinski PI, Sherrard RM, Kellar KJ.

Cerebellum. 2011 Dec;10(4):748-57. doi: 10.1007/s12311-011-0285-y.

22.

Selective induction of astrocytic gliosis generates deficits in neuronal inhibition.

Ortinski PI, Dong J, Mungenast A, Yue C, Takano H, Watson DJ, Haydon PG, Coulter DA.

Nat Neurosci. 2010 May;13(5):584-91. doi: 10.1038/nn.2535. Epub 2010 Apr 25.

23.

Differential tonic GABA conductances in striatal medium spiny neurons.

Ade KK, Janssen MJ, Ortinski PI, Vicini S.

J Neurosci. 2008 Jan 30;28(5):1185-97. doi: 10.1523/JNEUROSCI.3908-07.2008.

24.
25.

Deletion of the GABA(A) receptor alpha1 subunit increases tonic GABA(A) receptor current: a role for GABA uptake transporters.

Ortinski PI, Turner JR, Barberis A, Motamedi G, Yasuda RP, Wolfe BB, Kellar KJ, Vicini S.

J Neurosci. 2006 Sep 6;26(36):9323-31.

26.

Termination of epileptiform activity by cooling in rat hippocampal slice epilepsy models.

Motamedi GK, Salazar P, Smith EL, Lesser RP, Webber WR, Ortinski PI, Vicini S, Rogawski MA.

Epilepsy Res. 2006 Aug;70(2-3):200-10. Epub 2006 Jul 3.

PMID:
16815680
27.

The pheromone androstenol (5 alpha-androst-16-en-3 alpha-ol) is a neurosteroid positive modulator of GABAA receptors.

Kaminski RM, Marini H, Ortinski PI, Vicini S, Rogawski MA.

J Pharmacol Exp Ther. 2006 May;317(2):694-703. Epub 2006 Jan 13.

PMID:
16415088
28.

Expression of distinct alpha subunits of GABAA receptor regulates inhibitory synaptic strength.

Ortinski PI, Lu C, Takagaki K, Fu Z, Vicini S.

J Neurophysiol. 2004 Sep;92(3):1718-27. Epub 2004 Apr 21. Erratum in: J Neurophysiol. 2005 Jul;94(1):901.

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