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Items: 13

1.

CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas.

Jiang Y, Ortega-Molina A, Geng H, Ying HY, Hatzi K, Parsa S, McNally D, Wang L, Doane AS, Agirre X, Teater M, Meydan C, Li Z, Poloway D, Wang S, Ennishi D, Scott DW, Stengel KR, Kranz JE, Holson E, Sharma S, Young JW, Chu CS, Roeder RG, Shaknovich R, Hiebert SW, Gascoyne RD, Tam W, Elemento O, Wendel HG, Melnick AM.

Cancer Discov. 2017 Jan;7(1):38-53. doi: 10.1158/2159-8290.CD-16-0975. Epub 2016 Oct 12.

2.

PTEN recruitment controls synaptic and cognitive function in Alzheimer's models.

Knafo S, Sánchez-Puelles C, Palomer E, Delgado I, Draffin JE, Mingo J, Wahle T, Kaleka K, Mou L, Pereda-Perez I, Klosi E, Faber EB, Chapman HM, Lozano-Montes L, Ortega-Molina A, Ordóñez-Gutiérrez L, Wandosell F, Viña J, Dotti CG, Hall RA, Pulido R, Gerges NZ, Chan AM, Spaller MR, Serrano M, Venero C, Esteban JA.

Nat Neurosci. 2016 Mar;19(3):443-53. doi: 10.1038/nn.4225. Epub 2016 Jan 18.

PMID:
26780512
3.

The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development.

Ortega-Molina A, Boss IW, Canela A, Pan H, Jiang Y, Zhao C, Jiang M, Hu D, Agirre X, Niesvizky I, Lee JE, Chen HT, Ennishi D, Scott DW, Mottok A, Hother C, Liu S, Cao XJ, Tam W, Shaknovich R, Garcia BA, Gascoyne RD, Ge K, Shilatifard A, Elemento O, Nussenzweig A, Melnick AM, Wendel HG.

Nat Med. 2015 Oct;21(10):1199-208. doi: 10.1038/nm.3943. Epub 2015 Sep 14.

4.

Pharmacological inhibition of PI3K reduces adiposity and metabolic syndrome in obese mice and rhesus monkeys.

Ortega-Molina A, Lopez-Guadamillas E, Mattison JA, Mitchell SJ, Muñoz-Martin M, Iglesias G, Gutierrez VM, Vaughan KL, Szarowicz MD, González-García I, López M, Cebrián D, Martinez S, Pastor J, de Cabo R, Serrano M.

Cell Metab. 2015 Apr 7;21(4):558-70. doi: 10.1016/j.cmet.2015.02.017. Epub 2015 Mar 26.

5.

A cell engineering strategy to enhance the safety of stem cell therapies.

Oricchio E, Papapetrou EP, Lafaille F, Ganat YM, Kriks S, Ortega-Molina A, Mark WH, Teruya-Feldstein J, Huse JT, Reuter V, Sadelain M, Studer L, Wendel HG.

Cell Rep. 2014 Sep 25;8(6):1677-1685. doi: 10.1016/j.celrep.2014.08.039. Epub 2014 Sep 18.

6.

The PTEN/NRF2 axis promotes human carcinogenesis.

Rojo AI, Rada P, Mendiola M, Ortega-Molina A, Wojdyla K, Rogowska-Wrzesinska A, Hardisson D, Serrano M, Cuadrado A.

Antioxid Redox Signal. 2014 Dec 20;21(18):2498-514. doi: 10.1089/ars.2014.5843. Epub 2014 Jul 31.

7.

PTEN in cancer, metabolism, and aging.

Ortega-Molina A, Serrano M.

Trends Endocrinol Metab. 2013 Apr;24(4):184-9. doi: 10.1016/j.tem.2012.11.002. Epub 2012 Dec 12. Review.

8.

Regulation of the tumor suppressor PTEN by SUMO.

González-Santamaría J, Campagna M, Ortega-Molina A, Marcos-Villar L, de la Cruz-Herrera CF, González D, Gallego P, Lopitz-Otsoa F, Esteban M, Rodríguez MS, Serrano M, Rivas C.

Cell Death Dis. 2012 Sep 27;3:e393. doi: 10.1038/cddis.2012.135.

9.

Pten positively regulates brown adipose function, energy expenditure, and longevity.

Ortega-Molina A, Efeyan A, Lopez-Guadamillas E, Muñoz-Martin M, Gómez-López G, Cañamero M, Mulero F, Pastor J, Martinez S, Romanos E, Mar Gonzalez-Barroso M, Rial E, Valverde AM, Bischoff JR, Serrano M.

Cell Metab. 2012 Mar 7;15(3):382-94. doi: 10.1016/j.cmet.2012.02.001.

10.

A minimally invasive assay for individual assessment of the ATM/CHEK2/p53 pathway activity.

Kabacik S, Ortega-Molina A, Efeyan A, Finnon P, Bouffler S, Serrano M, Badie C.

Cell Cycle. 2011 Apr 1;10(7):1152-61. Epub 2011 Apr 1.

11.

Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression.

Efeyan A, Murga M, Martinez-Pastor B, Ortega-Molina A, Soria R, Collado M, Fernandez-Capetillo O, Serrano M.

PLoS One. 2009;4(5):e5475. doi: 10.1371/journal.pone.0005475. Epub 2009 May 7.

12.

Induction of p53-dependent senescence by the MDM2 antagonist nutlin-3a in mouse cells of fibroblast origin.

Efeyan A, Ortega-Molina A, Velasco-Miguel S, Herranz D, Vassilev LT, Serrano M.

Cancer Res. 2007 Aug 1;67(15):7350-7.

13.

Determination of Venus Winds by Ground-Based Radio Tracking of the VEGA Balloons.

Preston RA, Hildebrand CE, Purcell GH Jr, Ellis J, Stelzried CT, Finley SG, Sagdeev RZ, Linkin VM, Kerzhanovich VV, Altunin VI, Kogan LR, Kostenko VI, Matveenko LI, Pogrebenko SV, Strukov IA, Akim EL, Alexandrov YN, Armand NA, Bakitko RN, Vyshlov AS, Bogomolov AF, Gorchankov YN, Selivanov AS, Ivanov NM, Tichonov VF, Blamont JE, Boloh L, Laurans G, Boischot A, Biraud F, Ortega-Molina A, Rosolen C, Petit G.

Science. 1986 Mar 21;231(4744):1414-6.

PMID:
17748082

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