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Items: 33

1.

Tick saliva protein Evasin-3 modulates chemotaxis by disrupting CXCL8 interactions with glycosaminoglycans and CXCR2.

Denisov SS, Ippel JH, Heinzmann ACA, Koenen RR, Ortega-Gomez A, Soehnlein O, Hackeng TM, Dijkgraaf I.

J Biol Chem. 2019 Jun 24. pii: jbc.RA119.008902. doi: 10.1074/jbc.RA119.008902. [Epub ahead of print]

2.

Pro-Angiogenic Macrophage Phenotype to Promote Myocardial Repair.

Ferraro B, Leoni G, Hinkel R, Ormanns S, Paulin N, Ortega-Gomez A, Viola JR, de Jong R, Bongiovanni D, Bozoglu T, Maas SL, D'Amico M, Kessler T, Zeller T, Hristov M, Reutelingsperger C, Sager HB, Döring Y, Nahrendorf M, Kupatt C, Soehnlein O.

J Am Coll Cardiol. 2019 Jun 18;73(23):2990-3002. doi: 10.1016/j.jacc.2019.03.503.

3.

Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death.

Silvestre-Roig C, Braster Q, Wichapong K, Lee EY, Teulon JM, Berrebeh N, Winter J, Adrover JM, Santos GS, Froese A, Lemnitzer P, Ortega-Gómez A, Chevre R, Marschner J, Schumski A, Winter C, Perez-Olivares L, Pan C, Paulin N, Schoufour T, Hartwig H, González-Ramos S, Kamp F, Megens RTA, Mowen KA, Gunzer M, Maegdefessel L, Hackeng T, Lutgens E, Daemen M, von Blume J, Anders HJ, Nikolaev VO, Pellequer JL, Weber C, Hidalgo A, Nicolaes GAF, Wong GCL, Soehnlein O.

Nature. 2019 May;569(7755):236-240. doi: 10.1038/s41586-019-1167-6. Epub 2019 May 1.

PMID:
31043745
4.

Long non-coding RNAs: implications in targeted diagnoses, prognosis, and improved therapeutic strategies in human non- and triple-negative breast cancer.

Rodríguez Bautista R, Ortega Gómez A, Hidalgo Miranda A, Zentella Dehesa A, Villarreal-Garza C, Ávila-Moreno F, Arrieta O.

Clin Epigenetics. 2018 Jun 27;10:88. doi: 10.1186/s13148-018-0514-z. eCollection 2018. Review. Erratum in: Clin Epigenetics. 2018 Aug 8;10(1):106.

5.

Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis.

Winter C, Silvestre-Roig C, Ortega-Gomez A, Lemnitzer P, Poelman H, Schumski A, Winter J, Drechsler M, de Jong R, Immler R, Sperandio M, Hristov M, Zeller T, Nicolaes GAF, Weber C, Viola JR, Hidalgo A, Scheiermann C, Soehnlein O.

Cell Metab. 2018 Jul 3;28(1):175-182.e5. doi: 10.1016/j.cmet.2018.05.002. Epub 2018 May 31.

6.

Functional ex-vivo Imaging of Arterial Cellular Recruitment and Lipid Extravasation.

van der Vorst EPC, Maas SL, Ortega-Gomez A, Hameleers JMM, Bianchini M, Asare Y, Soehnlein O, Döring Y, Weber C, Megens RTA.

Bio Protoc. 2017 Jun 20;7(12). pii: 2344. doi: 10.21769/BioProtoc.2344.

7.

Differential gene expression profiles according to the Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society histopathological classification in lung adenocarcinoma subtypes.

Molina-Romero C, Rangel-Escareño C, Ortega-Gómez A, Alanis-Funes GJ, Avilés-Salas A, Avila-Moreno F, Mercado GE, Cardona AF, Hidalgo-Miranda A, Arrieta O.

Hum Pathol. 2017 Aug;66:188-199. doi: 10.1016/j.humpath.2017.06.002. Epub 2017 Jun 9.

PMID:
28603066
8.

Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARγ-Dependent Monocyte Differentiation and Function.

Bermudez B, Dahl TB, Medina I, Groeneweg M, Holm S, Montserrat-de la Paz S, Rousch M, Otten J, Herias V, Varela LM, Ranheim T, Yndestad A, Ortega-Gomez A, Abia R, Nagy L, Aukrust P, Muriana FJG, Halvorsen B, Biessen EAL.

Arterioscler Thromb Vasc Biol. 2017 Jun;37(6):1157-1167. doi: 10.1161/ATVBAHA.116.308187. Epub 2017 Apr 13.

PMID:
28408371
9.

Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.

von Hundelshausen P, Agten SM, Eckardt V, Blanchet X, Schmitt MM, Ippel H, Neideck C, Bidzhekov K, Leberzammer J, Wichapong K, Faussner A, Drechsler M, Grommes J, van Geffen JP, Li H, Ortega-Gomez A, Megens RT, Naumann R, Dijkgraaf I, Nicolaes GA, Döring Y, Soehnlein O, Lutgens E, Heemskerk JW, Koenen RR, Mayo KH, Hackeng TM, Weber C.

Sci Transl Med. 2017 Apr 5;9(384). pii: eaah6650. doi: 10.1126/scitranslmed.aah6650.

PMID:
28381538
10.

Postprandial triglyceride-rich lipoproteins promote lipid accumulation and apolipoprotein B-48 receptor transcriptional activity in human circulating and murine bone marrow neutrophils in a fatty acid-dependent manner.

Ortega-Gómez A, Varela LM, López S, Montserrat de la Paz S, Sánchez R, Muriana FJG, Bermúdez B, Abia R.

Mol Nutr Food Res. 2017 Sep;61(9). doi: 10.1002/mnfr.201600879. Epub 2017 Apr 28.

PMID:
28322000
11.

Cathepsin G Controls Arterial But Not Venular Myeloid Cell Recruitment.

Ortega-Gomez A, Salvermoser M, Rossaint J, Pick R, Brauner J, Lemnitzer P, Tilgner J, de Jong RJ, Megens RT, Jamasbi J, Döring Y, Pham CT, Scheiermann C, Siess W, Drechsler M, Weber C, Grommes J, Zarbock A, Walzog B, Soehnlein O.

Circulation. 2016 Oct 18;134(16):1176-1188. Epub 2016 Sep 22.

12.

Gene-expression profiles in lung adenocarcinomas related to chronic wood smoke or tobacco exposure.

Ortega-Gómez A, Rangel-Escareño C, Molina-Romero C, Macedo-Pérez EO, Avilés-Salas A, Lara-García A, Alanis-Funes G, Rodríguez-Bautista R, Hidalgo-Miranda A, Arrieta O.

Respir Res. 2016 Apr 20;17:42. doi: 10.1186/s12931-016-0346-3.

13.

Structure-Based Design of Peptidic Inhibitors of the Interaction between CC Chemokine Ligand 5 (CCL5) and Human Neutrophil Peptides 1 (HNP1).

Wichapong K, Alard JE, Ortega-Gomez A, Weber C, Hackeng TM, Soehnlein O, Nicolaes GA.

J Med Chem. 2016 May 12;59(9):4289-301. doi: 10.1021/acs.jmedchem.5b01952. Epub 2016 Feb 23.

PMID:
26871718
14.

Braf V600E mutation in melanoma: translational current scenario.

Guadarrama-Orozco JA, Ortega-Gómez A, Ruiz-García EB, Astudillo-de la Vega H, Meneses-García A, Lopez-Camarillo C.

Clin Transl Oncol. 2016 Sep;18(9):863-71. doi: 10.1007/s12094-015-1469-6. Epub 2016 Jan 29. Review.

PMID:
26825657
15.

Recruitment of classical monocytes can be inhibited by disturbing heteromers of neutrophil HNP1 and platelet CCL5.

Alard JE, Ortega-Gomez A, Wichapong K, Bongiovanni D, Horckmans M, Megens RT, Leoni G, Ferraro B, Rossaint J, Paulin N, Ng J, Ippel H, Suylen D, Hinkel R, Blanchet X, Gaillard F, D'Amico M, von Hundelshausen P, Zarbock A, Scheiermann C, Hackeng TM, Steffens S, Kupatt C, Nicolaes GA, Weber C, Soehnlein O.

Sci Transl Med. 2015 Dec 9;7(317):317ra196. doi: 10.1126/scitranslmed.aad5330.

PMID:
26659570
16.

Neutrophil-macrophage interplay in atherosclerosis: protease-mediated cytokine processing versus NET release.

Soehnlein O, Ortega-Gómez A, Döring Y, Weber C.

Thromb Haemost. 2015 Oct;114(4):866-7. doi: 10.1160/TH15-08-0623. Epub 2015 Aug 27. No abstract available.

PMID:
26310276
17.

Postprandial triglyceride-rich lipoproteins regulate perilipin-2 and perilipin-3 lipid-droplet-associated proteins in macrophages.

Varela LM, López S, Ortega-Gómez A, Bermúdez B, Buers I, Robenek H, Muriana FJ, Abia R.

J Nutr Biochem. 2015 Apr;26(4):327-36. doi: 10.1016/j.jnutbio.2014.11.007. Epub 2014 Dec 15.

PMID:
25595097
18.

High-density lipoproteins potentiate α1-antitrypsin therapy in elastase-induced pulmonary emphysema.

Moreno JA, Ortega-Gomez A, Rubio-Navarro A, Louedec L, Ho-Tin-Noé B, Caligiuri G, Nicoletti A, Levoye A, Plantier L, Meilhac O.

Am J Respir Cell Mol Biol. 2014 Oct;51(4):536-49. doi: 10.1165/rcmb.2013-0103OC.

PMID:
24787644
19.

Clustering effects on postprandial insulin secretion and sensitivity in response to meals with different fatty acid compositions.

Bermudez B, Ortega-Gomez A, Varela LM, Villar J, Abia R, Muriana FJ, Lopez S.

Food Funct. 2014 Jul 25;5(7):1374-80. doi: 10.1039/c4fo00067f.

PMID:
24752559
20.

Postprandial triglyceride-rich lipoproteins promote invasion of human coronary artery smooth muscle cells in a fatty-acid manner through PI3k-Rac1-JNK signaling.

Varela LM, Bermúdez B, Ortega-Gómez A, López S, Sánchez R, Villar J, Anguille C, Muriana FJ, Roux P, Abia R.

Mol Nutr Food Res. 2014 Jun;58(6):1349-64. doi: 10.1002/mnfr.201300749. Epub 2014 Feb 24.

PMID:
24668798
21.

Nanomedicine-based strategies for treatment of atherosclerosis.

Schiener M, Hossann M, Viola JR, Ortega-Gomez A, Weber C, Lauber K, Lindner LH, Soehnlein O.

Trends Mol Med. 2014 May;20(5):271-81. doi: 10.1016/j.molmed.2013.12.001. Epub 2014 Mar 1. Review.

PMID:
24594264
22.

Membrane composition and dynamics: a target of bioactive virgin olive oil constituents.

Lopez S, Bermudez B, Montserrat-de la Paz S, Jaramillo S, Varela LM, Ortega-Gomez A, Abia R, Muriana FJ.

Biochim Biophys Acta. 2014 Jun;1838(6):1638-56. doi: 10.1016/j.bbamem.2014.01.007. Epub 2014 Jan 16. Review.

23.

Nonanticoagulant heparin prevents histone-mediated cytotoxicity in vitro and improves survival in sepsis.

Wildhagen KC, García de Frutos P, Reutelingsperger CP, Schrijver R, Aresté C, Ortega-Gómez A, Deckers NM, Hemker HC, Soehnlein O, Nicolaes GA.

Blood. 2014 Feb 13;123(7):1098-101. doi: 10.1182/blood-2013-07-514984. Epub 2013 Nov 21.

24.

The effects of dietary fatty acids on the postprandial triglyceride-rich lipoprotein/apoB48 receptor axis in human monocyte/macrophage cells.

Varela LM, Ortega-Gomez A, Lopez S, Abia R, Muriana FJ, Bermudez B.

J Nutr Biochem. 2013 Dec;24(12):2031-9. doi: 10.1016/j.jnutbio.2013.07.004.

PMID:
24231096
25.

Phase II randomized, double-blind, placebo-controlled study of whole-brain irradiation with concomitant chloroquine for brain metastases.

Rojas-Puentes LL, Gonzalez-Pinedo M, Crismatt A, Ortega-Gomez A, Gamboa-Vignolle C, Nuñez-Gomez R, Dorantes-Gallareta Y, Arce-Salinas C, Arrieta O.

Radiat Oncol. 2013 Sep 8;8:209. doi: 10.1186/1748-717X-8-209.

26.

Resolution of inflammation: an integrated view.

Ortega-Gómez A, Perretti M, Soehnlein O.

EMBO Mol Med. 2013 May;5(5):661-74. doi: 10.1002/emmm.201202382. Epub 2013 Apr 17. Review.

27.

Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes.

Soehnlein O, Drechsler M, Döring Y, Lievens D, Hartwig H, Kemmerich K, Ortega-Gómez A, Mandl M, Vijayan S, Projahn D, Garlichs CD, Koenen RR, Hristov M, Lutgens E, Zernecke A, Weber C.

EMBO Mol Med. 2013 Mar;5(3):471-81. doi: 10.1002/emmm.201201717. Epub 2013 Feb 18.

28.

In vitro and in vivo evidence for the role of elastase shedding of CD163 in human atherothrombosis.

Moreno JA, Ortega-Gómez A, Delbosc S, Beaufort N, Sorbets E, Louedec L, Esposito-Farèse M, Tubach F, Nicoletti A, Steg PG, Michel JB, Feldman L, Meilhac O.

Eur Heart J. 2012 Jan;33(2):252-63. doi: 10.1093/eurheartj/ehr123. Epub 2011 May 23.

PMID:
21606088
29.

[Incidence of inflammatory bowel disease in the health area of Navalmoral de la Mata (Caceres, Spain) between 2000 and 2009].

Antón Martínez J, Ortega Gómez A, Arranz Carrero A, Molina Sánchez A, Alvarez García JF, Moreiras Jiménez JL, González Blanco P, Gutiérrez Sampedro N, Torres García E.

Gastroenterol Hepatol. 2010 Dec;33(10):694-9. doi: 10.1016/j.gastrohep.2010.08.004. Epub 2010 Nov 3. Spanish.

PMID:
21051113
30.

[Rectorrhagia due to oxygenated water].

Martínez JA, Molina Sánchez A, Ortega Gómez A.

Gastroenterol Hepatol. 2008 Apr;31(4):264. Spanish. No abstract available.

PMID:
18405493
31.

Myosin Va is proteolysed in rat cerebellar granule neurons after excitotoxic injury.

Alavez S, Morán J, Franco-Cea A, Ortega-Gómez A, Casaletti L, Cameron LC.

Neurosci Lett. 2004 Sep 9;367(3):404-9.

PMID:
15337275
32.

[Lumbosacral plexopathy and deep vein thrombosis associated with retroperitoneal malignant fibrous histiocytoma].

Calvo-Romero JM, Redondo-López JM, Ortega-Gómez A, Magro-Ledesma D.

Rev Neurol. 2000 Sep 16-30;31(6):595-6. Spanish. No abstract available.

PMID:
11055068
33.

[Hepatotoxic reaction associated with metformin and chlorpropamide treatment].

Crespo Valadés E, Ortega Gómez A, Alvarado Izquierdo MI, Magro Ledesma D.

Rev Clin Esp. 1999 Feb;199(2):118-9. Spanish. No abstract available.

PMID:
10216414

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