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Interplay of Nitric Oxide Synthase (NOS) and SrrAB in Modulation of Staphylococcus aureus Metabolism and Virulence.

James KL, Mogen AB, Brandwein JN, Orsini SS, Ridder MJ, Markiewicz MA, Bose JL, Rice KC.

Infect Immun. 2019 Jan 24;87(2). pii: e00570-18. doi: 10.1128/IAI.00570-18. Print 2019 Feb.


The t6A modification acts as a positive determinant for the anticodon nuclease PrrC, and is distinctively nonessential in Streptococcus mutans.

Bacusmo JM, Orsini SS, Hu J, DeMott M, Thiaville PC, Elfarash A, Paulines MJ, Rojas-Benítez D, Meineke B, Deutsch C, Iwata-Reuyl D, Limbach PA, Dedon PC, Rice KC, Shuman S, Crécy-Lagard V.

RNA Biol. 2018;15(4-5):508-517. doi: 10.1080/15476286.2017.1353861. Epub 2017 Sep 13.


Investigation of simulated microgravity effects on Streptococcus mutans physiology and global gene expression.

Orsini SS, Lewis AM, Rice KC.

NPJ Microgravity. 2017 Jan 12;3:4. doi: 10.1038/s41526-016-0006-4. eCollection 2017.

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