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Items: 1 to 50 of 118

1.

Nonlinear indentation of single human erythrocytes under application of a localized mechanical force.

Tognoni E, Orsini P, Pellegrino M.

Micron. 2019 Sep 30;127:102760. doi: 10.1016/j.micron.2019.102760. [Epub ahead of print]

PMID:
31614267
2.

A complex and cryptic intrachromosomal rearrangement generating the FIP1L1_PDGFRA in adult acute myeloid leukemia.

Coccaro N, Anelli L, Orsini P, Zagaria A, Minervini A, Impera L, Tota G, Minervini CF, Cumbo C, Parciante E, Coserva MR, Attolico I, Specchia G, Albano F.

Cancer Genet. 2019 Aug 21;239:8-12. doi: 10.1016/j.cancergen.2019.08.003. [Epub ahead of print]

PMID:
31450116
3.

Correction to Discovery of Entrectinib: A New 3-Aminoindazole as a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor.

Menichincheri M, Ardini E, Magnaghi P, Avanzi N, Banfi P, Bossi R, Buffa L, Canevari G, Ceriani L, Colombo M, Corti L, Donati D, Fasolini M, Felder E, Fiorelli C, Fiorentini F, Galvani A, Isacchi A, Borgia AL, Marchionni C, Nesi M, Orrenius C, Panzeri A, Pesenti E, Rusconi L, Saccardo MB, Vanotti E, Perrone E, Orsini P.

J Med Chem. 2019 Sep 12;62(17):8364. doi: 10.1021/acs.jmedchem.9b01259. Epub 2019 Aug 19. No abstract available.

PMID:
31424209
4.

Discovery of Stereospecific PARP-1 Inhibitor Isoindolinone NMS-P515.

Papeo G, Orsini P, Avanzi NR, Borghi D, Casale E, Ciomei M, Cirla A, Desperati V, Donati D, Felder ER, Galvani A, Guanci M, Isacchi A, Posteri H, Rainoldi S, Riccardi-Sirtori F, Scolaro A, Montagnoli A.

ACS Med Chem Lett. 2019 Mar 13;10(4):534-538. doi: 10.1021/acsmedchemlett.8b00569. eCollection 2019 Apr 11.

PMID:
30996792
5.

An antibody-drug conjugate directed to the ALK receptor demonstrates efficacy in preclinical models of neuroblastoma.

Sano R, Krytska K, Larmour CE, Raman P, Martinez D, Ligon GF, Lillquist JS, Cucchi U, Orsini P, Rizzi S, Pawel BR, Alvarado D, Mossé YP.

Sci Transl Med. 2019 Mar 13;11(483). pii: eaau9732. doi: 10.1126/scitranslmed.aau9732.

PMID:
30867324
6.

Droplet digital PCR for the quantification of Alu methylation status in hematological malignancies.

Orsini P, Impera L, Parciante E, Cumbo C, Minervini CF, Minervini A, Zagaria A, Anelli L, Coccaro N, Casieri P, Tota G, Brunetti C, Ricco A, Carluccio P, Specchia G, Albano F.

Diagn Pathol. 2018 Dec 22;13(1):98. doi: 10.1186/s13000-018-0777-x.

7.

An Orthopaedic Robotic-Assisted Rehabilitation Method of the Forearm in Virtual Reality Physiotherapy.

Padilla-Castañeda MA, Sotgiu E, Barsotti M, Frisoli A, Orsini P, Martiradonna A, Laddaga C, Bergamasco M.

J Healthc Eng. 2018 Aug 1;2018:7438609. doi: 10.1155/2018/7438609. eCollection 2018.

8.

Design and MinION testing of a nanopore targeted gene sequencing panel for chronic lymphocytic leukemia.

Orsini P, Minervini CF, Cumbo C, Anelli L, Zagaria A, Minervini A, Coccaro N, Tota G, Casieri P, Impera L, Parciante E, Brunetti C, Giordano A, Specchia G, Albano F.

Sci Rep. 2018 Aug 7;8(1):11798. doi: 10.1038/s41598-018-30330-y.

9.

Monitoring minimal residual disease by ddPCR in acute lymphoblastic leukemia associated with the FGFR1 gene rearrangement.

Coccaro N, Tota G, Zagaria A, Anelli L, Casieri P, Impera L, Minervini A, Minervini CF, Orsini P, Cumbo C, Parciante E, Delia M, Brunetti C, Specchia G, Albano F.

Int J Lab Hematol. 2018 Dec;40(6):e117-e120. doi: 10.1111/ijlh.12879. Epub 2018 Jun 28. No abstract available.

PMID:
29956473
10.

Droplet Digital PCR Is a Robust Tool for Monitoring Minimal Residual Disease in Adult Philadelphia-Positive Acute Lymphoblastic Leukemia.

Coccaro N, Anelli L, Zagaria A, Casieri P, Tota G, Orsini P, Impera L, Minervini A, Minervini CF, Cumbo C, Parciante E, Carluccio P, Brunetti C, Specchia G, Albano F.

J Mol Diagn. 2018 Jul;20(4):474-482. doi: 10.1016/j.jmoldx.2018.03.002. Epub 2018 Apr 3.

PMID:
29625246
11.

Genomic BCR-ABL1 breakpoint characterization by a multi-strategy approach for "personalized monitoring" of residual disease in chronic myeloid leukemia patients.

Cumbo C, Impera L, Minervini CF, Orsini P, Anelli L, Zagaria A, Coccaro N, Tota G, Minervini A, Casieri P, Brunetti C, Rossi AR, Parciante E, Specchia G, Albano F.

Oncotarget. 2018 Jan 5;9(13):10978-10986. doi: 10.18632/oncotarget.23971. eCollection 2018 Feb 16.

12.

RARA and RARG gene downregulation associated with EZH2 mutation in acute promyelocytic-like morphology leukemia.

Coccaro N, Zagaria A, Orsini P, Anelli L, Tota G, Casieri P, Impera L, Minervini A, Minervini CF, Cumbo C, Parciante E, Mestice A, Delia M, Brunetti C, Specchia G, Albano F.

Hum Pathol. 2018 Oct;80:82-86. doi: 10.1016/j.humpath.2018.02.023. Epub 2018 Mar 10.

PMID:
29530751
13.

A novel t(3;9)(q21.2; p24.3) associated with SMARCA2 and ZNF148 genes rearrangement in myelodysplastic syndrome.

Coccaro N, Brunetti C, Tota G, Pierri CL, Anelli L, Zagaria A, Casieri P, Impera L, Minervini CF, Minervini A, Cumbo C, Ricco A, Carluccio P, Orsini P, Specchia G, Albano F.

Leuk Lymphoma. 2018 Apr;59(4):996-999. doi: 10.1080/10428194.2017.1352093. Epub 2017 Jul 18. No abstract available.

PMID:
28718702
14.

Mutational analysis in BCR-ABL1 positive leukemia by deep sequencing based on nanopore MinION technology.

Minervini CF, Cumbo C, Orsini P, Anelli L, Zagaria A, Impera L, Coccaro N, Brunetti C, Minervini A, Casieri P, Tota G, Russo Rossi A, Specchia G, Albano F.

Exp Mol Pathol. 2017 Aug;103(1):33-37. doi: 10.1016/j.yexmp.2017.06.007. Epub 2017 Jun 27.

PMID:
28663031
15.

Systemic Mastocytosis with Associated Chronic Lymphocytic Leukemia: A Matter of Diseases or Prognostic Factors?

Zagaria A, Anelli L, Coccaro N, Tota G, Brunetti C, Minervini A, Casieri P, Impera L, Minervini CF, Giordano A, Orsini P, Cumbo C, Specchia G, Albano F.

Turk J Haematol. 2017 Aug 2;34(3):276-277. doi: 10.4274/tjh.2017.0014. Epub 2017 Mar 29. No abstract available.

16.

Droplet Digital PCR Is a Reliable Tool for Monitoring Minimal Residual Disease in Acute Promyelocytic Leukemia.

Brunetti C, Anelli L, Zagaria A, Minervini A, Minervini CF, Casieri P, Coccaro N, Cumbo C, Tota G, Impera L, Orsini P, Specchia G, Albano F.

J Mol Diagn. 2017 May;19(3):437-444. doi: 10.1016/j.jmoldx.2017.01.004. Epub 2017 Mar 6.

PMID:
28268092
17.

Droplet digital PCR analysis of NOTCH1 gene mutations in chronic lymphocytic leukemia.

Minervini A, Francesco Minervini C, Anelli L, Zagaria A, Casieri P, Coccaro N, Cumbo C, Tota G, Impera L, Orsini P, Brunetti C, Giordano A, Specchia G, Albano F.

Oncotarget. 2016 Dec 27;7(52):86469-86479. doi: 10.18632/oncotarget.13246.

18.

TP53 gene mutation analysis in chronic lymphocytic leukemia by nanopore MinION sequencing.

Minervini CF, Cumbo C, Orsini P, Brunetti C, Anelli L, Zagaria A, Minervini A, Casieri P, Coccaro N, Tota G, Impera L, Giordano A, Specchia G, Albano F.

Diagn Pathol. 2016 Oct 10;11(1):96.

19.

MYEOV gene overexpression in primary plasma cell leukemia with t(11;14)(q13;q32).

Coccaro N, Tota G, Anelli L, Zagaria A, Casieri P, Cellamare A, Minervini CF, Minervini A, Cumbo C, Impera L, Brunetti C, Orsini P, Parciante E, Mestice A, Specchia G, Albano F.

Oncol Lett. 2016 Aug;12(2):1460-1464. Epub 2016 Jun 22.

20.

Droplet digital PCR assay for quantifying of CALR mutant allelic burden in myeloproliferative neoplasms.

Anelli L, Zagaria A, Coccaro N, Tota G, Minervini A, Casieri P, Impera L, Minervini CF, Brunetti C, Ricco A, Orsini P, Cumbo C, Specchia G, Albano F.

Ann Hematol. 2016 Sep;95(9):1559-60. doi: 10.1007/s00277-016-2739-2. Epub 2016 Jul 1. No abstract available.

PMID:
27365140
21.

Asymmetric Tactile Foot Stimulation: How Postural Studies May Suggest New Views of Hypnotizability.

Solari G, Orsini P, Santarcangelo EL.

Int J Clin Exp Hypn. 2016 Jul-Sep;64(3):305-17. doi: 10.1080/00207144.2016.1171092.

PMID:
27267675
22.

Blink reflex in subjects with different hypnotizability: New findings for an old debate.

Santarcangelo EL, Briscese L, Capitani S, Orsini P, Varanini M, Rossi B, Carboncini MC.

Physiol Behav. 2016 Sep 1;163:288-293. doi: 10.1016/j.physbeh.2016.05.021. Epub 2016 May 13.

PMID:
27184234
23.

Discovery of Entrectinib: A New 3-Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor.

Menichincheri M, Ardini E, Magnaghi P, Avanzi N, Banfi P, Bossi R, Buffa L, Canevari G, Ceriani L, Colombo M, Corti L, Donati D, Fasolini M, Felder E, Fiorelli C, Fiorentini F, Galvani A, Isacchi A, Borgia AL, Marchionni C, Nesi M, Orrenius C, Panzeri A, Pesenti E, Rusconi L, Saccardo MB, Vanotti E, Perrone E, Orsini P.

J Med Chem. 2016 Apr 14;59(7):3392-408. doi: 10.1021/acs.jmedchem.6b00064. Epub 2016 Mar 30. Erratum in: J Med Chem. 2019 Sep 12;62(17):8364.

PMID:
27003761
24.

Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications.

Ardini E, Menichincheri M, Banfi P, Bosotti R, De Ponti C, Pulci R, Ballinari D, Ciomei M, Texido G, Degrassi A, Avanzi N, Amboldi N, Saccardo MB, Casero D, Orsini P, Bandiera T, Mologni L, Anderson D, Wei G, Harris J, Vernier JM, Li G, Felder E, Donati D, Isacchi A, Pesenti E, Magnaghi P, Galvani A.

Mol Cancer Ther. 2016 Apr;15(4):628-39. doi: 10.1158/1535-7163.MCT-15-0758. Epub 2016 Mar 3.

25.

Overexpression of the LSAMP and TUSC7 genes in acute myeloid leukemia following microdeletion/duplication of chromosome 3.

Coccaro N, Zagaria A, Tota G, Anelli L, Orsini P, Casieri P, Cellamare A, Minervini A, Impera L, Minervini CF, Brunetti C, Mestice A, Carluccio P, Cumbo C, Specchia G, Albano F.

Cancer Genet. 2015 Oct;208(10):517-22. doi: 10.1016/j.cancergen.2015.07.006. Epub 2015 Aug 4.

PMID:
26345353
26.

Discovery of 2-[1-(4,4-Difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide (NMS-P118): A Potent, Orally Available, and Highly Selective PARP-1 Inhibitor for Cancer Therapy.

Papeo G, Posteri H, Borghi D, Busel AA, Caprera F, Casale E, Ciomei M, Cirla A, Corti E, D'Anello M, Fasolini M, Forte B, Galvani A, Isacchi A, Khvat A, Krasavin MY, Lupi R, Orsini P, Perego R, Pesenti E, Pezzetta D, Rainoldi S, Riccardi-Sirtori F, Scolaro A, Sola F, Zuccotto F, Felder ER, Donati D, Montagnoli A.

J Med Chem. 2015 Sep 10;58(17):6875-98. doi: 10.1021/acs.jmedchem.5b00680. Epub 2015 Aug 26.

PMID:
26222319
27.

BCR-ABL1 e6a2 transcript in chronic myeloid leukemia: biological features and molecular monitoring by droplet digital PCR.

Zagaria A, Anelli L, Coccaro N, Tota G, Casieri P, Cellamare A, Impera L, Brunetti C, Minervini A, Minervini CF, Delia M, Cumbo C, Orsini P, Specchia G, Albano F.

Virchows Arch. 2015 Sep;467(3):357-63. doi: 10.1007/s00428-015-1802-z. Epub 2015 Jul 7.

PMID:
26149409
28.

Absolute quantification of the pretreatment PML-RARA transcript defines the relapse risk in acute promyelocytic leukemia.

Albano F, Zagaria A, Anelli L, Coccaro N, Tota G, Brunetti C, Minervini CF, Impera L, Minervini A, Cellamare A, Orsini P, Cumbo C, Casieri P, Specchia G.

Oncotarget. 2015 May 30;6(15):13269-77.

29.

Myelodysplastic syndrome with 5q deletion following IgM monoclonal gammopathy, showing gene mutation MYD88 L265P.

Zagaria A, Coccaro N, Tota G, Anelli L, Minervini A, Casieri P, Cellamare A, Minervini CF, Brunetti C, Ricco A, Orsini P, Cumbo C, Specchia G, Albano F.

Blood Cells Mol Dis. 2015 Jan;54(1):51-2. doi: 10.1016/j.bcmd.2014.07.022. Epub 2014 Aug 20.

PMID:
25159121
30.

Revisiting the association between hypnotisability and blink rate.

Di Gruttola F, Orsini P, Carboncini MC, Rossi B, Santarcangelo EL.

Exp Brain Res. 2014 Dec;232(12):3763-9. doi: 10.1007/s00221-014-4073-z. Epub 2014 Aug 20.

PMID:
25138913
31.

Centromeric fragment of chromosome 7 in atypical chronic myeloid leukemia with the SET binding protein 1 gene mutation.

Coccaro N, Tota G, Anelli L, Zagaria A, Casieri P, Cellamare A, Minervini A, Minervini CF, Brunetti C, Ricco A, Orsini P, Cumbo C, Specchia G, Albano F.

Leuk Lymphoma. 2015 Mar;56(3):826-8. doi: 10.3109/10428194.2014.939968. Epub 2014 Aug 4. No abstract available.

PMID:
24991718
32.

A new technique to investigate vestibulo-spinal reflexes.

Grasso C, Orsini P, Bruschini L, Manzoni D, Barresi M.

Arch Ital Biol. 2013 Jun;151(2):54-66. doi: 10.4449/aib.v151i2.1487.

PMID:
24442983
33.

Lymphoid enhancer binding factor-1 (LEF1) expression as a prognostic factor in adult acute promyelocytic leukemia.

Albano F, Zagaria A, Anelli L, Orsini P, Minervini CF, Impera L, Casieri P, Coccaro N, Tota G, Brunetti C, Minervini A, Pastore D, Carluccio P, Mestice A, Cellamare A, Specchia G.

Oncotarget. 2014 Feb 15;5(3):649-58.

34.

BCL6 corepressor gene dysregulation due to chromosomal translocation in acute myeloid leukemia: a new mechanism based on long non-coding RNA dislocation?

Zagaria A, Anelli L, Casieri P, Coccaro N, Tota G, Minervini CF, Minervini A, Impera L, Brunetti C, Orsini P, Cellamare A, Specchia G, Albano F.

Leuk Lymphoma. 2014 Sep;55(9):2199-201. doi: 10.3109/10428194.2013.874009. Epub 2014 Feb 24. No abstract available.

PMID:
24325634
35.

Two-photon polymerization of sub-micrometric patterned surfaces: investigation of cell-substrate interactions and improved differentiation of neuron-like cells.

Marino A, Ciofani G, Filippeschi C, Pellegrino M, Pellegrini M, Orsini P, Pasqualetti M, Mattoli V, Mazzolai B.

ACS Appl Mater Interfaces. 2013 Dec 26;5(24):13012-21. doi: 10.1021/am403895k. Epub 2013 Dec 13.

PMID:
24309089
36.

Gender difference in response predictors after 1-year exenatide therapy twice daily in type 2 diabetic patients: a real world experience.

Anichini R, Cosimi S, Di Carlo A, Orsini P, De Bellis A, Seghieri G, Franconi F, Baccetti F.

Diabetes Metab Syndr Obes. 2013 Apr 8;6:123-9. doi: 10.2147/DMSO.S42729. Print 2013.

37.

Emergency hospitalizations for severe hypoglycaemia in patients with type 2 diabetes.

Di Cianni G, Goretti C, Onetto F, Lencioni C, Orsini P, Sannino C, Turco A, Pratesi M.

Acta Diabetol. 2013 Jun;50(3):463-4. doi: 10.1007/s00592-013-0473-y. Epub 2013 Mar 26. No abstract available.

PMID:
23529773
38.

Measuring the elastic properties of living cells through the analysis of current-displacement curves in scanning ion conductance microscopy.

Pellegrino M, Pellegrini M, Orsini P, Tognoni E, Ascoli C, Baschieri P, Dinelli F.

Pflugers Arch. 2012 Sep;464(3):307-16. doi: 10.1007/s00424-012-1127-6. Epub 2012 Jun 29.

PMID:
22744227
39.

Weak hydrostatic forces in far-scanning ion conductance microscopy used to guide neuronal growth cones.

Pellegrino M, Orsini P, Pellegrini M, Baschieri P, Dinelli F, Petracchi D, Tognoni E, Ascoli C.

Neurosci Res. 2011 Mar;69(3):234-40. doi: 10.1016/j.neures.2010.11.009. Epub 2010 Dec 10.

PMID:
21146567
40.

Anaplastic Lymphoma Kinase: role in specific tumours, and development of small molecule inhibitors for cancer therapy.

Ardini E, Magnaghi P, Orsini P, Galvani A, Menichincheri M.

Cancer Lett. 2010 Dec 28;299(2):81-94. doi: 10.1016/j.canlet.2010.09.001. Epub 2010 Oct 8. Review.

PMID:
20934803
41.

Cdc7 kinase inhibitors: 5-heteroaryl-3-carboxamido-2-aryl pyrroles as potential antitumor agents. 1. Lead finding.

Menichincheri M, Albanese C, Alli C, Ballinari D, Bargiotti A, Caldarelli M, Ciavolella A, Cirla A, Colombo M, Colotta F, Croci V, D'Alessio R, D'Anello M, Ermoli A, Fiorentini F, Forte B, Galvani A, Giordano P, Isacchi A, Martina K, Molinari A, Moll JK, Montagnoli A, Orsini P, Orzi F, Pesenti E, Pillan A, Roletto F, Scolaro A, Tatò M, Tibolla M, Valsasina B, Varasi M, Vianello P, Volpi D, Santocanale C, Vanotti E.

J Med Chem. 2010 Oct 28;53(20):7296-315. doi: 10.1021/jm100504d.

PMID:
20873740
42.

Can imagery become reality?

Santarcangelo EL, Scattina E, Carli G, Ghelarducci B, Orsini P, Manzoni D.

Exp Brain Res. 2010 Oct;206(3):329-35. doi: 10.1007/s00221-010-2412-2. Epub 2010 Sep 17.

PMID:
20848275
43.

Tuning of human vestibulospinal reflexes by leg rotation.

Grasso C, Barresi M, Scattina E, Orsini P, Vignali E, Bruschini L, Manzoni D.

Hum Mov Sci. 2011 Apr;30(2):296-313. doi: 10.1016/j.humov.2010.07.018. Epub 2010 Sep 1.

PMID:
20813417
44.

Crystal structures of anaplastic lymphoma kinase in complex with ATP competitive inhibitors.

Bossi RT, Saccardo MB, Ardini E, Menichincheri M, Rusconi L, Magnaghi P, Orsini P, Avanzi N, Borgia AL, Nesi M, Bandiera T, Fogliatto G, Bertrand JA.

Biochemistry. 2010 Aug 17;49(32):6813-25. doi: 10.1021/bi1005514.

PMID:
20695522
45.

Dysfunction of the magnocellular stream in Alzheimer's disease evaluated by pattern electroretinograms and visual evoked potentials.

Sartucci F, Borghetti D, Bocci T, Murri L, Orsini P, Porciatti V, Origlia N, Domenici L.

Brain Res Bull. 2010 May 31;82(3-4):169-76. doi: 10.1016/j.brainresbull.2010.04.001. Epub 2010 Apr 10.

46.

Optimization of 6,6-dimethyl pyrrolo[3,4-c]pyrazoles: Identification of PHA-793887, a potent CDK inhibitor suitable for intravenous dosing.

Brasca MG, Albanese C, Alzani R, Amici R, Avanzi N, Ballinari D, Bischoff J, Borghi D, Casale E, Croci V, Fiorentini F, Isacchi A, Mercurio C, Nesi M, Orsini P, Pastori W, Pesenti E, Pevarello P, Roussel P, Varasi M, Volpi D, Vulpetti A, Ciomei M.

Bioorg Med Chem. 2010 Mar 1;18(5):1844-53. doi: 10.1016/j.bmc.2010.01.042. Epub 2010 Jan 25.

PMID:
20153204
47.

Recombinant human TSH and ablation of post-surgical thyroid remnants in differentiated thyroid cancer: the effect of pre-treatment with furosemide and furosemide plus lithium.

Barbaro D, Grosso M, Boni G, Lapi P, Pasquini C, Orsini P, Turco A, Meucci G, Marzola MC, Berti P, Miccoli P, Mariani G, Rubello D.

Eur J Nucl Med Mol Imaging. 2010 Feb;37(2):242-9. doi: 10.1007/s00259-009-1254-2. Epub 2009 Sep 4.

PMID:
19760415
48.

Poly(ADP-ribose) polymerase inhibition in cancer therapy: are we close to maturity?

Papeo G, Forte B, Orsini P, Perrera C, Posteri H, Scolaro A, Montagnoli A.

Expert Opin Ther Pat. 2009 Oct;19(10):1377-400. doi: 10.1517/13543770903215883. Review.

PMID:
19743897
49.

Use of scanning ion conductance microscopy to guide and redirect neuronal growth cones.

Pellegrino M, Orsini P, De Gregorio F.

Neurosci Res. 2009 Jul;64(3):290-6. doi: 10.1016/j.neures.2009.03.014. Epub 2009 Apr 8.

PMID:
19447298
50.

'Gamma' band oscillatory response to chromatic stimuli in volunteers and patients with idiopathic Parkinson's disease.

Sannita WG, Carozzo S, Orsini P, Domenici L, Porciatti V, Fioretto M, Garbarino S, Sartucci F.

Vision Res. 2009 Mar;49(7):726-34. doi: 10.1016/j.visres.2009.01.018. Epub 2009 Feb 14.

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