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Items: 36

1.

Distinct oncogenes drive different genome and epigenome alterations in human mammary epithelial cells.

Fonti C, Saumet A, Abi-Khalil A, Orsetti B, Cleroux E, Bender A, Dumas M, Schmitt E, Colinge J, Jacot W, Weber M, Sardet C, du Manoir S, Theillet C.

Int J Cancer. 2019 Sep 1;145(5):1299-1311. doi: 10.1002/ijc.32413. Epub 2019 Jun 10.

2.

An auristatin-based antibody-drug conjugate targeting HER3 enhances the radiation response in pancreatic cancer.

Bourillon L, Bourgier C, Gaborit N, Garambois V, Llès E, Zampieri A, Ogier C, Jarlier M, Radosevic-Robin N, Orsetti B, Delpech H, Theillet C, Colombo PE, Azria D, Pèlegrin A, Larbouret C, Chardès T.

Int J Cancer. 2019 Oct 1;145(7):1838-1851. doi: 10.1002/ijc.32273. Epub 2019 Apr 1.

3.

Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53.

Arena G, Cissé MY, Pyrdziak S, Chatre L, Riscal R, Fuentes M, Arnold JJ, Kastner M, Gayte L, Bertrand-Gaday C, Nay K, Angebault-Prouteau C, Murray K, Chabi B, Koechlin-Ramonatxo C, Orsetti B, Vincent C, Casas F, Marine JC, Etienne-Manneville S, Bernex F, Lombès A, Cameron CE, Dubouchaud H, Ricchetti M, Linares LK, Le Cam L.

Mol Cell. 2018 Feb 15;69(4):594-609.e8. doi: 10.1016/j.molcel.2018.01.023.

4.

Circulating tumor cells: potential markers of minimal residual disease in ovarian cancer? a study of the OVCAD consortium.

Obermayr E, Bednarz-Knoll N, Orsetti B, Weier HU, Lambrechts S, Castillo-Tong DC, Reinthaller A, Braicu EI, Mahner S, Sehouli J, Vergote I, Theillet C, Zeillinger R, Brandt B.

Oncotarget. 2017 Nov 16;8(63):106415-106428. doi: 10.18632/oncotarget.22468. eCollection 2017 Dec 5.

5.

Histone deacetylase 9 regulates breast cancer cell proliferation and the response to histone deacetylase inhibitors.

Lapierre M, Linares A, Dalvai M, Duraffourd C, Bonnet S, Boulahtouf A, Rodriguez C, Jalaguier S, Assou S, Orsetti B, Balaguer P, Maudelonde T, Blache P, Bystricky K, Boulle N, Cavaillès V.

Oncotarget. 2016 Apr 12;7(15):19693-708. doi: 10.18632/oncotarget.7564.

6.

TOM1L1 drives membrane delivery of MT1-MMP to promote ERBB2-induced breast cancer cell invasion.

Chevalier C, Collin G, Descamps S, Touaitahuata H, Simon V, Reymond N, Fernandez L, Milhiet PE, Georget V, Urbach S, Lasorsa L, Orsetti B, Boissière-Michot F, Lopez-Crapez E, Theillet C, Roche S, Benistant C.

Nat Commun. 2016 Feb 22;7:10765. doi: 10.1038/ncomms10765.

7.

Nuclear cathepsin D enhances TRPS1 transcriptional repressor function to regulate cell cycle progression and transformation in human breast cancer cells.

Bach AS, Derocq D, Laurent-Matha V, Montcourrier P, Sebti S, Orsetti B, Theillet C, Gongora C, Pattingre S, Ibing E, Roger P, Linares LK, Reinheckel T, Meurice G, Kaiser FJ, Gespach C, Liaudet-Coopman E.

Oncotarget. 2015 Sep 29;6(29):28084-103. doi: 10.18632/oncotarget.4394.

8.

Impact of chromosomal instability on colorectal cancer progression and outcome.

Orsetti B, Selves J, Bascoul-Mollevi C, Lasorsa L, Gordien K, Bibeau F, Massemin B, Paraf F, Soubeyran I, Hostein I, Dapremont V, Guimbaud R, Cazaux C, Longy M, Theillet C.

BMC Cancer. 2014 Feb 22;14:121. doi: 10.1186/1471-2407-14-121.

9.

Breast tumor PDXs are genetically plastic and correspond to a subset of aggressive cancers prone to relapse.

du Manoir S, Orsetti B, Bras-Gonçalves R, Nguyen TT, Lasorsa L, Boissière F, Massemin B, Colombo PE, Bibeau F, Jacot W, Theillet C.

Mol Oncol. 2014 Mar;8(2):431-43. doi: 10.1016/j.molonc.2013.11.010. Epub 2013 Dec 19.

10.

Long-term detection of human adipose-derived mesenchymal stem cells after intraarticular injection in SCID mice.

Toupet K, Maumus M, Peyrafitte JA, Bourin P, van Lent PL, Ferreira R, Orsetti B, Pirot N, Casteilla L, Jorgensen C, Noël D.

Arthritis Rheum. 2013 Jul;65(7):1786-94. doi: 10.1002/art.37960.

11.

An array CGH based genomic instability index (G2I) is predictive of clinical outcome in breast cancer and reveals a subset of tumors without lymph node involvement but with poor prognosis.

Bonnet F, Guedj M, Jones N, Sfar S, Brouste V, Elarouci N, Banneau G, Orsetti B, Primois C, de Lara CT, Debled M, de Mascarel I, Theillet C, Sévenet N, de Reynies A, MacGrogan G, Longy M.

BMC Med Genomics. 2012 Nov 27;5:54. doi: 10.1186/1755-8794-5-54.

12.

Estrogen and retinoic acid antagonistically regulate several microRNA genes to control aerobic glycolysis in breast cancer cells.

Saumet A, Vetter G, Bouttier M, Antoine E, Roubert C, Orsetti B, Theillet C, Lecellier CH.

Mol Biosyst. 2012 Oct 30;8(12):3242-53. doi: 10.1039/c2mb25298h.

PMID:
23064179
13.

Analysis of SRC oncogenic signaling in colorectal cancer by stable isotope labeling with heavy amino acids in mouse xenografts.

Sirvent A, Vigy O, Orsetti B, Urbach S, Roche S.

Mol Cell Proteomics. 2012 Dec;11(12):1937-50. doi: 10.1074/mcp.M112.018168. Epub 2012 Sep 29.

14.

The non-crosslinking fixative RCL2®-CS100 is compatible with both pathology diagnosis and molecular analyses.

Boissière-Michot F, Denouël A, Boulle N, Guillaume C, Orsetti B, Lopez-Crapez E, Chateau MC, Bibeau F.

Pathol Oncol Res. 2013 Jan;19(1):41-53. doi: 10.1007/s12253-012-9556-2. Epub 2012 Aug 15.

PMID:
22893391
15.

A refined molecular taxonomy of breast cancer.

Guedj M, Marisa L, de Reynies A, Orsetti B, Schiappa R, Bibeau F, MacGrogan G, Lerebours F, Finetti P, Longy M, Bertheau P, Bertrand F, Bonnet F, Martin AL, Feugeas JP, Bièche I, Lehmann-Che J, Lidereau R, Birnbaum D, Bertucci F, de Thé H, Theillet C.

Oncogene. 2012 Mar 1;31(9):1196-206. doi: 10.1038/onc.2011.301. Epub 2011 Jul 25.

16.

Prognostic significance of TRIM24/TIF-1α gene expression in breast cancer.

Chambon M, Orsetti B, Berthe ML, Bascoul-Mollevi C, Rodriguez C, Duong V, Gleizes M, Thénot S, Bibeau F, Theillet C, Cavaillès V.

Am J Pathol. 2011 Apr;178(4):1461-9. doi: 10.1016/j.ajpath.2010.12.026.

17.

Mining microarray data to predict the histological grade of a breast cancer.

Fabregue M, Bringay S, Poncelet P, Teisseire M, Orsetti B.

J Biomed Inform. 2011 Dec;44 Suppl 1:S12-6. doi: 10.1016/j.jbi.2011.03.002. Epub 2011 Mar 21.

18.

Genomic markers for ovarian cancer at chromosomes 1, 8 and 17 revealed by array CGH analysis.

Dimova I, Orsetti B, Negre V, Rouge C, Ursule L, Lasorsa L, Dimitrov R, Doganov N, Toncheva D, Theillet C.

Tumori. 2009 May-Jun;95(3):357-66.

PMID:
19688977
19.

Lobular and ductal carcinomas of the breast have distinct genomic and expression profiles.

Bertucci F, Orsetti B, Nègre V, Finetti P, Rougé C, Ahomadegbe JC, Bibeau F, Mathieu MC, Treilleux I, Jacquemier J, Ursule L, Martinec A, Wang Q, Bénard J, Puisieux A, Birnbaum D, Theillet C.

Oncogene. 2008 Sep 11;27(40):5359-72. doi: 10.1038/onc.2008.158. Epub 2008 May 19.

20.

Genetic profiling of chromosome 1 in breast cancer: mapping of regions of gains and losses and identification of candidate genes on 1q.

Orsetti B, Nugoli M, Cervera N, Lasorsa L, Chuchana P, Rougé C, Ursule L, Nguyen C, Bibeau F, Rodriguez C, Theillet C.

Br J Cancer. 2006 Nov 20;95(10):1439-47. Epub 2006 Oct 24.

21.

Chordin is underexpressed in ovarian tumors and reduces tumor cell motility.

Moll F, Millet C, Noël D, Orsetti B, Bardin A, Katsaros D, Jorgensen C, Garcia M, Theillet C, Pujol P, François V.

FASEB J. 2006 Feb;20(2):240-50.

PMID:
16449796
22.

Comprehensive profiling of 8p11-12 amplification in breast cancer.

Gelsi-Boyer V, Orsetti B, Cervera N, Finetti P, Sircoulomb F, Rougé C, Lasorsa L, Letessier A, Ginestier C, Monville F, Esteyriès S, Adélaïde J, Esterni B, Henry C, Ethier SP, Bibeau F, Mozziconacci MJ, Charafe-Jauffret E, Jacquemier J, Bertucci F, Birnbaum D, Theillet C, Chaffanet M.

Mol Cancer Res. 2005 Dec;3(12):655-67.

23.

Genomic and expression profiling of chromosome 17 in breast cancer reveals complex patterns of alterations and novel candidate genes.

Orsetti B, Nugoli M, Cervera N, Lasorsa L, Chuchana P, Ursule L, Nguyen C, Redon R, du Manoir S, Rodriguez C, Theillet C.

Cancer Res. 2004 Sep 15;64(18):6453-60.

24.

Amplification of the BRCA2 pathway gene EMSY in sporadic breast cancer is related to negative outcome.

Rodriguez C, Hughes-Davies L, Vallès H, Orsetti B, Cuny M, Ursule L, Kouzarides T, Theillet C.

Clin Cancer Res. 2004 Sep 1;10(17):5785-91.

25.

ABCG2 overexpression in colon cancer cells resistant to SN38 and in irinotecan-treated metastases.

Candeil L, Gourdier I, Peyron D, Vezzio N, Copois V, Bibeau F, Orsetti B, Scheffer GL, Ychou M, Khan QA, Pommier Y, Pau B, Martineau P, Del Rio M.

Int J Cancer. 2004 May 10;109(6):848-54.

26.

A recurrent chromosome translocation breakpoint in breast and pancreatic cancer cell lines targets the neuregulin/NRG1 gene.

Adélaïde J, Huang HE, Murati A, Alsop AE, Orsetti B, Mozziconacci MJ, Popovici C, Ginestier C, Letessier A, Basset C, Courtay-Cahen C, Jacquemier J, Theillet C, Birnbaum D, Edwards PA, Chaffanet M.

Genes Chromosomes Cancer. 2003 Aug;37(4):333-45.

PMID:
12800145
27.

Genetic variability in MCF-7 sublines: evidence of rapid genomic and RNA expression profile modifications.

Nugoli M, Chuchana P, Vendrell J, Orsetti B, Ursule L, Nguyen C, Birnbaum D, Douzery EJ, Cohen P, Theillet C.

BMC Cancer. 2003 Apr 24;3:13.

28.

MYEOV: a candidate gene for DNA amplification events occurring centromeric to CCND1 in breast cancer.

Janssen JW, Cuny M, Orsetti B, Rodriguez C, Vallés H, Bartram CR, Schuuring E, Theillet C.

Int J Cancer. 2002 Dec 20;102(6):608-14.

29.

Reciprocal translocations in breast tumor cell lines: cloning of a t(3;20) that targets the FHIT gene.

Popovici C, Basset C, Bertucci F, Orsetti B, Adélaide J, Mozziconacci MJ, Conte N, Murati A, Ginestier C, Charafe-Jauffret E, Ethier SP, Lafage-Pochitaloff M, Theillet C, Birnbaum D, Chaffanet M.

Genes Chromosomes Cancer. 2002 Nov;35(3):204-18.

PMID:
12353263
30.

The human chordin gene encodes several differentially expressed spliced variants with distinct BMP opposing activities.

Millet C, Lemaire P, Orsetti B, Guglielmi P, François V.

Mech Dev. 2001 Aug;106(1-2):85-96.

31.

[Genomic profiling: from molecular cytogenetics to DNA arrays].

Theillet C, Orsetti B, Redon R, Manoir SD.

Bull Cancer. 2001 Mar;88(3):261-8. Review. French.

32.

Molecular cytogenetic analysis of breast cancer cell lines.

Davidson JM, Gorringe KL, Chin SF, Orsetti B, Besret C, Courtay-Cahen C, Roberts I, Theillet C, Caldas C, Edwards PA.

Br J Cancer. 2000 Nov;83(10):1309-17.

33.

Human E2F5 gene is oncogenic in primary rodent cells and is amplified in human breast tumors.

Polanowska J, Le Cam L, Orsetti B, Vallés H, Fabbrizio E, Fajas L, Taviaux S, Theillet C, Sardet C.

Genes Chromosomes Cancer. 2000 May;28(1):126-30.

PMID:
10738311
35.

[Application of the PRINS technique for chromosome examination in fetal cells present in maternal blood].

Orsetti B, Lefort G, Boulot P, Andreo B, Pellestor F.

Ann Pathol. 1998 Nov;18(5):377-84. French.

PMID:
9864573
36.

Fetal cells in maternal blood: the use of primed in situ (PRINS) labelling technique for fetal cell detection and sex assessment.

Orsetti B, Lefort G, Boulot P, Andreo B, Pellestor F.

Prenat Diagn. 1998 Oct;18(10):1014-22.

PMID:
9826893

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