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Items: 1 to 50 of 76

1.

Cellular recognition and trafficking of amorphous silica nanoparticles by macrophage scavenger receptor A.

Orr GA, Chrisler WB, Cassens KJ, Tan R, Tarasevich BJ, Markillie LM, Zangar RC, Thrall BD.

Nanotoxicology. 2011 Sep;5(3):296-311. doi: 10.3109/17435390.2010.513836. Epub 2010 Sep 17.

PMID:
20849212
2.

Human immunodeficiency virus (HIV) antigens and RNA in HIV-seronegative women with cervical intraepithelial neoplasia.

Basu J, Romney SL, Angeletti RH, Vermund SH, Nieves E, Kadish AS, Mikhail MS, Orr GA.

AIDS Res Hum Retroviruses. 2009 Mar;25(3):249-59. doi: 10.1089/aid.2008.0096.

3.

A photoaffinity analogue of discodermolide specifically labels a peptide in beta-tubulin.

Xia S, Kenesky CS, Rucker PV, Smith AB 3rd, Orr GA, Horwitz SB.

Biochemistry. 2006 Oct 3;45(39):11762-75.

PMID:
17002277
4.

Molecular cloning and characterization of the protein kinase A regulatory subunit of Trypanosoma cruzi.

Huang H, Weiss LM, Nagajyothi F, Tanowitz HB, Wittner M, Orr GA, Bao Y.

Mol Biochem Parasitol. 2006 Oct;149(2):242-5. Epub 2006 Jun 14. No abstract available.

PMID:
16815565
5.

Insights into the mechanism of microtubule stabilization by Taxol.

Xiao H, Verdier-Pinard P, Fernandez-Fuentes N, Burd B, Angeletti R, Fiser A, Horwitz SB, Orr GA.

Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10166-10173. doi: 10.1073/pnas.0603704103. Epub 2006 Jun 26.

6.

Rat organic anion transporting protein 1A1 (Oatp1a1): purification and phosphopeptide assignment.

Xiao Y, Nieves E, Angeletti RH, Orr GA, Wolkoff AW.

Biochemistry. 2006 Mar 14;45(10):3357-69.

7.

Detection of human betaV-tubulin expression in epithelial cancer cell lines by tubulin proteomics.

Verdier-Pinard P, Shahabi S, Wang F, Burd B, Xiao H, Goldberg GL, Orr GA, Horwitz SB.

Biochemistry. 2005 Dec 6;44(48):15858-70.

PMID:
16313188
8.

Interaction with PDZK1 is required for expression of organic anion transporting protein 1A1 on the hepatocyte surface.

Wang P, Wang JJ, Xiao Y, Murray JW, Novikoff PM, Angeletti RH, Orr GA, Lan D, Silver DL, Wolkoff AW.

J Biol Chem. 2005 Aug 26;280(34):30143-9. Epub 2005 Jun 30.

9.

A highly epothilone B-resistant A549 cell line with mutations in tubulin that confer drug dependence.

Yang CP, Verdier-Pinard P, Wang F, Lippaine-Horvath E, He L, Li D, Höfle G, Ojima I, Orr GA, Horwitz SB.

Mol Cancer Ther. 2005 Jun;4(6):987-95.

10.

Mechanisms of Taxol resistance related to microtubules.

Orr GA, Verdier-Pinard P, McDaid H, Horwitz SB.

Oncogene. 2003 Oct 20;22(47):7280-95. Review.

11.

Direct analysis of tubulin expression in cancer cell lines by electrospray ionization mass spectrometry.

Verdier-Pinard P, Wang F, Burd B, Angeletti RH, Horwitz SB, Orr GA.

Biochemistry. 2003 Oct 21;42(41):12019-27.

PMID:
14556633
12.

Analysis of tubulin isotypes and mutations from taxol-resistant cells by combined isoelectrofocusing and mass spectrometry.

Verdier-Pinard P, Wang F, Martello L, Burd B, Orr GA, Horwitz SB.

Biochemistry. 2003 May 13;42(18):5349-57.

PMID:
12731876
13.

Elevated levels of microtubule destabilizing factors in a Taxol-resistant/dependent A549 cell line with an alpha-tubulin mutation.

Martello LA, Verdier-Pinard P, Shen HJ, He L, Torres K, Orr GA, Horwitz SB.

Cancer Res. 2003 Mar 15;63(6):1207-13.

14.

Molecular cloning and expression of the catalytic subunit of protein kinase A from Trypanosoma cruzi.

Huang H, Werner C, Weiss LM, Wittner M, Orr GA.

Int J Parasitol. 2002 Aug;32(9):1107-15.

PMID:
12117493
15.

Novel molecules that interact with microtubules and have functional activity similar to Taxol.

He L, Orr GA, Horwitz SB.

Drug Discov Today. 2001 Nov 15;6(22):1153-1164.

PMID:
11700217
16.

Identification by mass spectrometry of a new alpha-tubulin isotype expressed in human breast and lung carcinoma cell lines.

Rao S, Aberg F, Nieves E, Band Horwitz S, Orr GA.

Biochemistry. 2001 Feb 20;40(7):2096-103.

PMID:
11329278
17.

A common pharmacophore for Taxol and the epothilones based on the biological activity of a taxane molecule lacking a C-13 side chain.

He L, Jagtap PG, Kingston DG, Shen HJ, Orr GA, Horwitz SB.

Biochemistry. 2000 Apr 11;39(14):3972-8.

PMID:
10747785
18.

Identification of novel serine/threonine protein phosphatases in Trypanosoma cruzi: a potential role in control of cytokinesis and morphology.

Orr GA, Werner C, Xu J, Bennett M, Weiss LM, Takvorkan P, Tanowitz HB, Wittner M.

Infect Immun. 2000 Mar;68(3):1350-8.

19.
21.

Analysis of the major microsporidian polar tube proteins.

Keohane EM, Orr GA, Takvorian PM, Cali A, Tanowitz HB, Wittner M, Weiss LM.

J Eukaryot Microbiol. 1999 Sep-Oct;46(5):29S-30S. No abstract available.

PMID:
10519234
23.

Polar tube proteins of microsporidia of the family encephalitozoonidae.

Keohane EM, Orr GA, Takvorian PM, Cali A, Tanowitz HB, Wittner M, Weiss LM.

J Eukaryot Microbiol. 1999 Jan-Feb;46(1):1-5.

PMID:
10188255
24.

Photoaffinity labeling approach to map the Taxol-binding site on the microtubule.

Orr GA, Rao S, Swindell CS, Kingston DG, Horwitz SB.

Methods Enzymol. 1998;298:238-52. No abstract available.

PMID:
9751886
25.

The molecular characterization of the major polar tube protein gene from Encephalitozoon hellem, a microsporidian parasite of humans.

Keohane EM, Orr GA, Zhang HS, Takvorian PM, Cali A, Tanowitz HB, Wittner M, Weiss LM.

Mol Biochem Parasitol. 1998 Aug 1;94(2):227-36.

26.

Identification of in vivo phosphorylation sites for basic-directed kinases in murine mdr1b P-glycoprotein by combination of mass spectrometry and site-directed mutagenesis.

Glavy JS, Wolfson M, Nieves E, Han EK, Yang CP, Horwitz SB, Orr GA.

Methods Enzymol. 1998;292:342-58. No abstract available.

PMID:
9711566
27.

Identification of the domains of photoincorporation of the 3'- and 7-benzophenone analogues of taxol in the carboxyl-terminal half of murine mdr1b P-glycoprotein.

Wu Q, Bounaud PY, Kuduk SD, Yang CP, Ojima I, Horwitz SB, Orr GA.

Biochemistry. 1998 Aug 11;37(32):11272-9.

PMID:
9698374
28.
30.
31.

Domain organization of murine mdr1b P-glycoprotein: the cytoplasmic linker region is a potential dimerization domain.

Juvvadi SR, Glavy JS, Horwitz SB, Orr GA.

Biochem Biophys Res Commun. 1997 Jan 13;230(2):442-7.

PMID:
9016799
32.

Purification and characterization of human microsporidian polar tube proteins.

Keohane EM, Orr GA, Takvorian PM, Cali A, Tanowitz HB, Wittner M, Weiss LM.

J Eukaryot Microbiol. 1996 Sep-Oct;43(5):100S. No abstract available.

PMID:
8822888
33.

Purification and characterization of a microsporidian polar tube protein.

Keohane EM, Orr GA, Takvorian PM, Cali A, Tanowitz HB, Wittner M, Weiss LM.

Mol Biochem Parasitol. 1996 Aug;79(2):255-9. No abstract available.

PMID:
8855564
34.
35.

Two-dimensional protein electrophoresis and multiple hypothesis testing to detect potential serum protein biomarkers in children with fetal alcohol syndrome.

Robinson MK, Myrick JE, Henderson LO, Coles CD, Powell MK, Orr GA, Lemkin PF.

Electrophoresis. 1995 Jul;16(7):1176-83.

PMID:
7498162
36.

The protein disease database.

Lemkin PF, Orr GA, Goldstein MP, Creed J, Whitley E, Myrick JE, Merril CR.

Electrophoresis. 1995 Jul;16(7):1175. No abstract available.

PMID:
7498161
37.

Trypanosoma cruzi induces endothelin release from endothelial cells.

Wittner M, Christ GJ, Huang H, Weiss LM, Hatcher VB, Morris SA, Orr GA, Berman JW, Zeballos GA, Douglas SA, et al.

J Infect Dis. 1995 Feb;171(2):493-7.

PMID:
7844399
38.

The Protein Disease Database of human body fluids: II. Computer methods and data issues.

Lemkin PF, Orr GA, Goldstein MP, Creed GJ, Myrick JE, Merril CR.

Appl Theor Electrophor. 1995;5(2):55-72.

PMID:
8573600
39.

Development of a directory of genetic probes as a shared institutional resource.

Orr GA, Rogan PK.

Comput Methods Programs Biomed. 1995 Jan;46(1):35-9.

PMID:
7743779
41.

Purification and characterization of three isolectins of soybean agglutinin. Evidence for C-terminal truncation by electrospray ionization mass spectrometry.

Mandal DK, Nieves E, Bhattacharyya L, Orr GA, Roboz J, Yu QT, Brewer CF.

Eur J Biochem. 1994 Apr 1;221(1):547-53.

42.

3'-(p-azidobenzamido)taxol photolabels the N-terminal 31 amino acids of beta-tubulin.

Rao S, Krauss NE, Heerding JM, Swindell CS, Ringel I, Orr GA, Horwitz SB.

J Biol Chem. 1994 Feb 4;269(5):3132-4.

43.

Identification of the major phosphorylation domain of murine mdr1b P-glycoprotein. Analysis of the protein kinase A and protein kinase C phosphorylation sites.

Orr GA, Han EK, Browne PC, Nieves E, O'Connor BM, Yang CP, Horwitz SB.

J Biol Chem. 1993 Nov 25;268(33):25054-62.

44.

Trypanosoma cruzi: stage expression of calmodulin-binding proteins.

Orr GA, Tanowitz HB, Wittner M.

Exp Parasitol. 1992 Mar;74(2):127-33.

PMID:
1740174
45.
46.

A human endothelial cell membrane protein that binds Staphylococcus aureus in vitro.

Tompkins DC, Hatcher VB, Patel D, Orr GA, Higgins LL, Lowy FD.

J Clin Invest. 1990 Apr;85(4):1248-54.

47.

2-Iminobiotin-containing reagent and affinity columns.

Fudem-Goldin B, Orr GA.

Methods Enzymol. 1990;184:167-73. No abstract available.

PMID:
2388568
48.

Biochemical and immunological characterization of the flagellar-associated regulatory subunit of a type II cyclic adenosine 5'-monophosphate-dependent protein kinase.

Horowitz JA, Voulalas P, Wasco W, MacLeod J, Paupard MC, Orr GA.

Arch Biochem Biophys. 1989 May 1;270(2):411-8.

PMID:
2650622
49.
50.

Identification and characterization of calmodulin-binding proteins in mammalian sperm flagella.

Wasco WM, Kincaid RL, Orr GA.

J Biol Chem. 1989 Mar 25;264(9):5104-11.

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