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Items: 1 to 50 of 248

1.

Quantitative Mapping of Oxidative Stress Response to Lithium Cobalt Oxide Nanoparticles in Single Cells Using Multiplexed in Situ Gene Expression Analysis.

Cui Y, Melby ES, Mensch AC, Laudadio ED, Hang MN, Dohnalkova A, Hu D, Hamers RJ, Orr G.

Nano Lett. 2019 Mar 13;19(3):1990-1997. doi: 10.1021/acs.nanolett.8b05172. Epub 2019 Feb 21.

PMID:
30773885
2.

Tumor Retention of Enzyme-Responsive Pt(II) Drug-Loaded Nanoparticles Imaged by Nanoscale Secondary Ion Mass Spectrometry and Fluorescence Microscopy.

Proetto MT, Callmann CE, Cliff J, Szymanski CJ, Hu D, Howell SB, Evans JE, Orr G, Gianneschi NC.

ACS Cent Sci. 2018 Nov 28;4(11):1477-1484. doi: 10.1021/acscentsci.8b00444. Epub 2018 Oct 23.

3.

Reference genes for accurate normalization of gene expression in wood-decomposing fungi.

Zhang J, Mitchell HD, Markillie LM, Gaffrey MJ, Orr G, Schilling J.

Fungal Genet Biol. 2019 Feb;123:33-40. doi: 10.1016/j.fgb.2018.11.005. Epub 2018 Dec 5.

PMID:
30529285
4.

Impact of lithiated cobalt oxide and phosphate nanoparticles on rainbow trout gill epithelial cells.

Melby ES, Cui Y, Borgatta J, Mensch AC, Hang MN, Chrisler WB, Dohnalkova A, Van Gilder JM, Alvarez CM, Smith JN, Hamers RJ, Orr G.

Nanotoxicology. 2018 Dec;12(10):1166-1181. doi: 10.1080/17435390.2018.1508785. Epub 2018 Nov 19.

PMID:
30451563
5.

Iatrogenic cannula-associated ocular injuries during anterior segment surgery: time to re-think luer-lock design?

Wilde C, Ross AR, Orr G, Dua H.

Eye (Lond). 2019 Feb;33(2):341-342. doi: 10.1038/s41433-018-0250-9. Epub 2018 Oct 25. No abstract available.

PMID:
30361488
6.

Dichomitus squalens partially tailors its molecular responses to the composition of solid wood.

Daly P, López SC, Peng M, Lancefield CS, Purvine SO, Kim YM, Zink EM, Dohnalkova A, Singan VR, Lipzen A, Dilworth D, Wang M, Ng V, Robinson E, Orr G, Baker SE, Bruijnincx PCA, Hildén KS, Grigoriev IV, Mäkelä MR, de Vries RP.

Environ Microbiol. 2018 Nov;20(11):4141-4156. doi: 10.1111/1462-2920.14416. Epub 2018 Oct 18.

PMID:
30246402
7.

Malic Acid Carbon Dots: From Super-resolution Live-Cell Imaging to Highly Efficient Separation.

Zhi B, Cui Y, Wang S, Frank BP, Williams DN, Brown RP, Melby ES, Hamers RJ, Rosenzweig Z, Fairbrother DH, Orr G, Haynes CL.

ACS Nano. 2018 Jun 26;12(6):5741-5752. doi: 10.1021/acsnano.8b01619. Epub 2018 Jun 15.

PMID:
29883099
8.

Multiple mechanisms drive phage infection efficiency in nearly identical hosts.

Howard-Varona C, Hargreaves KR, Solonenko NE, Markillie LM, White RA 3rd, Brewer HM, Ansong C, Orr G, Adkins JN, Sullivan MB.

ISME J. 2018 Jun;12(6):1605-1618. doi: 10.1038/s41396-018-0099-8. Epub 2018 Mar 22.

9.

Multi-time series RNA-seq analysis of Enterobacter lignolyticus SCF1 during growth in lignin-amended medium.

Orellana R, Chaput G, Markillie LM, Mitchell H, Gaffrey M, Orr G, DeAngelis KM.

PLoS One. 2017 Oct 19;12(10):e0186440. doi: 10.1371/journal.pone.0186440. eCollection 2017.

10.

Fluctuation localization imaging-based fluorescence in situ hybridization (fliFISH) for accurate detection and counting of RNA copies in single cells.

Cui Y, Hu D, Markillie LM, Chrisler WB, Gaffrey MJ, Ansong C, Sussel L, Orr G.

Nucleic Acids Res. 2018 Jan 25;46(2):e7. doi: 10.1093/nar/gkx874.

11.

High resolution visualization and exo-proteomics reveal the physiological role of XlnR and AraR in plant biomass colonization and degradation by Aspergillus niger.

Kowalczyk JE, Khosravi C, Purvine S, Dohnalkova A, Chrisler WB, Orr G, Robinson E, Zink E, Wiebenga A, Peng M, Battaglia E, Baker S, de Vries RP.

Environ Microbiol. 2017 Nov;19(11):4587-4598. doi: 10.1111/1462-2920.13923. Epub 2017 Oct 20.

PMID:
29027734
12.

Regulation of infection efficiency in a globally abundant marine Bacteriodetes virus.

Howard-Varona C, Roux S, Dore H, Solonenko NE, Holmfeldt K, Markillie LM, Orr G, Sullivan MB.

ISME J. 2017 Aug;11(8):1942. doi: 10.1038/ismej.2017.92.

13.

Mutations That Alter the Bacterial Cell Envelope Increase Lipid Production.

Lemmer KC, Zhang W, Langer SJ, Dohnalkova AC, Hu D, Lemke RA, Piotrowski JS, Orr G, Noguera DR, Donohue TJ.

MBio. 2017 May 23;8(3). pii: e00513-17. doi: 10.1128/mBio.00513-17.

14.

An evaluation of experiences and views of Scottish leadership training opportunities amongst primary care professionals.

Power A, Allbutt H, Munro L, MacLeod M, Kennedy S, Cameron D, Scoular K, Orr G, Gillies J.

Educ Prim Care. 2017 May;28(3):159-164. doi: 10.1080/14739879.2016.1266239. Epub 2016 Dec 30.

PMID:
28034342
15.

Self-Monitoring Utilization Patterns Among Individuals in an Incentivized Program for Healthy Behaviors.

Kim JY, Wineinger NE, Taitel M, Radin JM, Akinbosoye O, Jiang J, Nikzad N, Orr G, Topol E, Steinhubl S.

J Med Internet Res. 2016 Nov 17;18(11):e292.

16.

Cells Respond to Distinct Nanoparticle Properties with Multiple Strategies As Revealed by Single-Cell RNA-Seq.

Mitchell HD, Markillie LM, Chrisler WB, Gaffrey MJ, Hu D, Szymanski CJ, Xie Y, Melby ES, Dohnalkova A, Taylor RC, Grate EK, Cooley SK, McDermott JE, Heredia-Langner A, Orr G.

ACS Nano. 2016 Nov 22;10(11):10173-10185. Epub 2016 Oct 31.

PMID:
27788331
17.

Localizing gene regulation reveals a staggered wood decay mechanism for the brown rot fungus Postia placenta.

Zhang J, Presley GN, Hammel KE, Ryu JS, Menke JR, Figueroa M, Hu D, Orr G, Schilling JS.

Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):10968-73. doi: 10.1073/pnas.1608454113. Epub 2016 Sep 12.

18.

Regulation of infection efficiency in a globally abundant marine Bacteriodetes virus.

Howard-Varona C, Roux S, Dore H, Solonenko NE, Holmfeldt K, Markillie LM, Orr G, Sullivan MB.

ISME J. 2017 Jan;11(1):284-295. doi: 10.1038/ismej.2016.81. Epub 2016 May 17. Erratum in: ISME J. 2017 Aug;11(8):1942.

19.

Biological Responses to Engineered Nanomaterials: Needs for the Next Decade.

Murphy CJ, Vartanian AM, Geiger FM, Hamers RJ, Pedersen J, Cui Q, Haynes CL, Carlson EE, Hernandez R, Klaper RD, Orr G, Rosenzweig Z.

ACS Cent Sci. 2015 Jun 24;1(3):117-23. doi: 10.1021/acscentsci.5b00182. Epub 2015 Jun 9. Review.

20.

Chemical imaging of molecular changes in a hydrated single cell by dynamic secondary ion mass spectrometry and super-resolution microscopy.

Hua X, Szymanski C, Wang Z, Zhou Y, Ma X, Yu J, Evans J, Orr G, Liu S, Zhu Z, Yu XY.

Integr Biol (Camb). 2016 May 16;8(5):635-44. doi: 10.1039/c5ib00308c. Epub 2016 Apr 7.

PMID:
27053104
21.

Cellular Delivery of Nanoparticles Revealed with Combined Optical and Isotopic Nanoscopy.

Proetto MT, Anderton CR, Hu D, Szymanski CJ, Zhu Z, Patterson JP, Kammeyer JK, Nilewski LG, Rush AM, Bell NC, Evans JE, Orr G, Howell SB, Gianneschi NC.

ACS Nano. 2016 Apr 26;10(4):4046-54. doi: 10.1021/acsnano.5b06477. Epub 2016 Mar 29.

PMID:
27022832
22.

Antigen Binding and Site-Directed Labeling of Biosilica-Immobilized Fusion Proteins Expressed in Diatoms.

Ford NR, Hecht KA, Hu D, Orr G, Xiong Y, Squier TC, Rorrer GL, Roesijadi G.

ACS Synth Biol. 2016 Mar 18;5(3):193-9. doi: 10.1021/acssynbio.5b00191. Epub 2016 Jan 25.

PMID:
26746113
23.

Compartmentalized microchannel array for high-throughput analysis of single cell polarized growth and dynamics.

Geng T, Bredeweg EL, Szymanski CJ, Liu B, Baker SE, Orr G, Evans JE, Kelly RT.

Sci Rep. 2015 Nov 4;5:16111. doi: 10.1038/srep16111.

24.

Lesson of the month 1: Seeing snowflakes.

Patel A, Aslam A, Orr G, Perkins W.

Clin Med (Lond). 2015 Aug;15(4):394-5. doi: 10.7861/clinmedicine.15-4-394.

25.

Lipopolysaccharide Density and Structure Govern the Extent and Distance of Nanoparticle Interaction with Actual and Model Bacterial Outer Membranes.

Jacobson KH, Gunsolus IL, Kuech TR, Troiano JM, Melby ES, Lohse SE, Hu D, Chrisler WB, Murphy CJ, Orr G, Geiger FM, Haynes CL, Pedersen JA.

Environ Sci Technol. 2015 Sep 1;49(17):10642-50. doi: 10.1021/acs.est.5b01841. Epub 2015 Aug 12.

26.

Shifts in oxidation states of cerium oxide nanoparticles detected inside intact hydrated cells and organelles.

Szymanski CJ, Munusamy P, Mihai C, Xie Y, Hu D, Gilles MK, Tyliszczak T, Thevuthasan S, Baer DR, Orr G.

Biomaterials. 2015 Sep;62:147-54. doi: 10.1016/j.biomaterials.2015.05.042. Epub 2015 May 28.

27.

Comprehensive Metabolomic, Lipidomic and Microscopic Profiling of Yarrowia lipolytica during Lipid Accumulation Identifies Targets for Increased Lipogenesis.

Pomraning KR, Wei S, Karagiosis SA, Kim YM, Dohnalkova AC, Arey BW, Bredeweg EL, Orr G, Metz TO, Baker SE.

PLoS One. 2015 Apr 23;10(4):e0123188. doi: 10.1371/journal.pone.0123188. eCollection 2015.

28.

Effects of charge and surface ligand properties of nanoparticles on oxidative stress and gene expression within the gut of Daphnia magna.

Dominguez GA, Lohse SE, Torelli MD, Murphy CJ, Hamers RJ, Orr G, Klaper RD.

Aquat Toxicol. 2015 May;162:1-9. doi: 10.1016/j.aquatox.2015.02.015. Epub 2015 Feb 28.

PMID:
25734859
29.

Alexa fluor-labeled fluorescent cellulose nanocrystals for bioimaging solid cellulose in spatially structured microenvironments.

Grate JW, Mo KF, Shin Y, Vasdekis A, Warner MG, Kelly RT, Orr G, Hu D, Dehoff KJ, Brockman FJ, Wilkins MJ.

Bioconjug Chem. 2015 Mar 18;26(3):593-601. doi: 10.1021/acs.bioconjchem.5b00048. Epub 2015 Mar 2.

PMID:
25730280
30.

Electroporation of functional bacterial effectors into mammalian cells.

Sontag RL, Mihai C, Orr G, Savchenko A, Skarina T, Cui H, Cort JR, Adkins JN, Brown RN.

J Vis Exp. 2015 Jan 19;(95):52296. doi: 10.3791/52296.

31.

Transcriptomic and proteomic dynamics in the metabolism of a diazotrophic cyanobacterium, Cyanothece sp. PCC 7822 during a diurnal light-dark cycle.

Welkie D, Zhang X, Markillie ML, Taylor R, Orr G, Jacobs J, Bhide K, Thimmapuram J, Gritsenko M, Mitchell H, Smith RD, Sherman LA.

BMC Genomics. 2014 Dec 29;15:1185. doi: 10.1186/1471-2164-15-1185.

32.

Distinct strains of Toxoplasma gondii feature divergent transcriptomes regardless of developmental stage.

Croken MM, Ma Y, Markillie LM, Taylor RC, Orr G, Weiss LM, Kim K.

PLoS One. 2014 Nov 13;9(11):e111297. doi: 10.1371/journal.pone.0111297. eCollection 2014.

33.

Facile method to stain the bacterial cell surface for super-resolution fluorescence microscopy.

Gunsolus IL, Hu D, Mihai C, Lohse SE, Lee CS, Torelli MD, Hamers RJ, Murhpy CJ, Orr G, Haynes CL.

Analyst. 2014 Jun 21;139(12):3174-8. doi: 10.1039/c4an00574k. Epub 2014 May 9.

34.

High CD49f expression is associated with osteosarcoma tumor progression: a study using patient-derived primary cell cultures.

Penfornis P, Cai DZ, Harris MR, Walker R, Licini D, Fernandes JD, Orr G, Koganti T, Hicks C, Induru S, Meyer MS, Khokha R, Barr J, Pochampally RR.

Cancer Med. 2014 Aug;3(4):796-811. doi: 10.1002/cam4.249. Epub 2014 May 7.

35.

The highly conserved MraZ protein is a transcriptional regulator in Escherichia coli.

Eraso JM, Markillie LM, Mitchell HD, Taylor RC, Orr G, Margolin W.

J Bacteriol. 2014 Jun;196(11):2053-66. doi: 10.1128/JB.01370-13. Epub 2014 Mar 21.

36.

Enzyme-directed assembly of nanoparticles in tumors monitored by in vivo whole animal imaging and ex vivo super-resolution fluorescence imaging.

Chien MP, Carlini AS, Hu D, Barback CV, Rush AM, Hall DJ, Orr G, Gianneschi NC.

J Am Chem Soc. 2013 Dec 18;135(50):18710-3. doi: 10.1021/ja408182p. Epub 2013 Dec 5.

37.

Intracellular accumulation dynamics and fate of zinc ions in alveolar epithelial cells exposed to airborne ZnO nanoparticles at the air-liquid interface.

Mihai C, Chrisler WB, Xie Y, Hu D, Szymanski CJ, Tolic A, Klein JA, Smith JN, Tarasevich BJ, Orr G.

Nanotoxicology. 2015 Feb;9(1):9-22. doi: 10.3109/17435390.2013.859319. Epub 2013 Dec 2.

38.

Analysis of carbohydrate storage granules in the diazotrophic cyanobacterium Cyanothece sp. PCC 7822.

Welkie DG, Sherman DM, Chrisler WB, Orr G, Sherman LA.

Photosynth Res. 2013 Nov;118(1-2):25-36. doi: 10.1007/s11120-013-9941-z. Epub 2013 Oct 19.

PMID:
24142038
39.

Understanding super-resolution nanoscopy and its biological applications in cell imaging.

Hu D, Zhao B, Xie Y, Orr G, Li AD.

Phys Chem Chem Phys. 2013 Sep 28;15(36):14856-61. doi: 10.1039/c3cp51629f.

PMID:
23739871
40.

Three human cell types respond to multi-walled carbon nanotubes and titanium dioxide nanobelts with cell-specific transcriptomic and proteomic expression patterns.

Tilton SC, Karin NJ, Tolic A, Xie Y, Lai X, Hamilton RF Jr, Waters KM, Holian A, Witzmann FA, Orr G.

Nanotoxicology. 2014 Aug;8(5):533-48. doi: 10.3109/17435390.2013.803624. Epub 2013 Jun 7.

41.

Interlaboratory evaluation of in vitro cytotoxicity and inflammatory responses to engineered nanomaterials: the NIEHS Nano GO Consortium.

Xia T, Hamilton RF, Bonner JC, Crandall ED, Elder A, Fazlollahi F, Girtsman TA, Kim K, Mitra S, Ntim SA, Orr G, Tagmount M, Taylor AJ, Telesca D, Tolic A, Vulpe CD, Walker AJ, Wang X, Witzmann FA, Wu N, Xie Y, Zink JI, Nel A, Holian A.

Environ Health Perspect. 2013 Jun;121(6):683-90. doi: 10.1289/ehp.1306561. Epub 2013 May 6.

42.

Multi-omic data integration links deleted in breast cancer 1 (DBC1) degradation to chromatin remodeling in inflammatory response.

Nakayasu ES, Brown RN, Ansong C, Sydor MA, Imtiaz S, Mihai C, Sontag R, Hixson KK, Monroe ME, Sobreira TJ, Orr G, Petyuk VA, Yang F, Smith RD, Adkins JN.

Mol Cell Proteomics. 2013 Aug;12(8):2136-47. doi: 10.1074/mcp.M112.026138. Epub 2013 May 2.

43.

Preparation and Characterization Challenges to Understanding Environmental and Biological Impacts of Nanoparticles.

Karakoti AS, Munusamy P, Hostetler K, Kodali V, Kuchibhatla S, Orr G, Pounds JG, Teeguarden JG, Thrall BD, Baer DR.

Surf Interface Anal. 2012 Aug;44(5):882-889. Epub 2012 Apr 17.

44.

A pilot study assessing the impact of a fortified supplementary food on the health and well-being of crèche children and adult TB patients in South Africa.

Rudolph M, Kroll F, Beery M, Marinda E, Sobiecki JF, Douglas G, Orr G.

PLoS One. 2013;8(1):e55544. doi: 10.1371/journal.pone.0055544. Epub 2013 Jan 30.

45.

Safe and consistent method of spot-welding platinum thermocouple wires and foils for high temperature measurements.

Orr G, Roth M.

Rev Sci Instrum. 2012 Aug;83(8):084901. doi: 10.1063/1.4746383.

PMID:
22938323
46.

The need for evidence-based, non-drug medicine.

Ventegodt S, Orr G, Merrick J.

Int J Adolesc Med Health. 2011 Nov 4;24(2):113-9. doi: 10.1515/ijamh.2012.017. Review.

PMID:
22909920
47.

Aerosolized ZnO nanoparticles induce toxicity in alveolar type II epithelial cells at the air-liquid interface.

Xie Y, Williams NG, Tolic A, Chrisler WB, Teeguarden JG, Maddux BL, Pounds JG, Laskin A, Orr G.

Toxicol Sci. 2012 Feb;125(2):450-61. doi: 10.1093/toxsci/kfr251. Epub 2011 Sep 28.

48.

Testing in EHS: What is the Current Status of Experimentation?

Baer DR, Karakoti AS, Munusamy P, Thrall BD, Pounds JG, Teeguarden JG, Amonette JE, Orr G, Tratnyek PG, Nurmi JT.

Proc IEEE Conf Nanotechnol. 2011:18-19.

49.

ISDD: A computational model of particle sedimentation, diffusion and target cell dosimetry for in vitro toxicity studies.

Hinderliter PM, Minard KR, Orr G, Chrisler WB, Thrall BD, Pounds JG, Teeguarden JG.

Part Fibre Toxicol. 2010 Nov 30;7(1):36. doi: 10.1186/1743-8977-7-36.

50.

Functionalized nanoporous silica for the removal of heavy metals from biological systems: adsorption and application.

Yantasee W, Rutledge RD, Chouyyok W, Sukwarotwat V, Orr G, Warner CL, Warner MG, Fryxell GE, Wiacek RJ, Timchalk C, Addleman RS.

ACS Appl Mater Interfaces. 2010 Oct;2(10):2749-58. doi: 10.1021/am100616b.

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