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Items: 1 to 50 of 376

1.

The Fostering Resilience through Art in Medical Education (FRAME) workshop: a partnership with the Philadelphia Museum of Art.

Orr AR, Moghbeli N, Swain A, Bassett B, Niepold S, Rizzo A, DeLisser HM.

Adv Med Educ Pract. 2019 May 27;10:361-369. doi: 10.2147/AMEP.S194575. eCollection 2019.

2.

A Novel Role for the AnxA1-Fpr2/ALX Signaling Axis as a Key Regulator of Platelet Function to Promote Resolution of Inflammation.

Senchenkova EY, Ansari J, Becker F, Vital SA, Al-Yafeai Z, Sparkenbaugh EM, Pawlinski R, Stokes KY, Carroll JL, Dragoi AM, Qin CX, Ritchie RH, Sun H, Cuellar-Saenz HH, Rubinstein MR, Han YW, Orr AW, Perretti M, Granger DN, Gavins FNE.

Circulation. 2019 Jun 3. doi: 10.1161/CIRCULATIONAHA.118.039345. [Epub ahead of print]

PMID:
31154815
3.

Characterizing drip patterns in bloodstain pattern analysis: An investigation of the influence of droplet impact velocity and number of droplets on static pattern features.

Boos K, Orr A, Illes M, Stotesbury T.

Forensic Sci Int. 2019 Aug;301:55-66. doi: 10.1016/j.forsciint.2019.05.002. Epub 2019 May 9.

PMID:
31128409
4.

Prescribing in chronic severe hepatic impairment.

Wilcock A, Charlesworth S, Prentice W, Selby P, McKenna M, Cripps S, Considine A, Orr A, Wright M, Mihalyo M, Oxberry S.

J Pain Symptom Manage. 2019 May 9. pii: S0885-3924(19)30239-8. doi: 10.1016/j.jpainsymman.2019.04.034. [Epub ahead of print]

PMID:
31077785
5.

Pharmacologic Inhibition of Epidermal Growth Factor Receptor Suppresses Nonalcoholic Fatty Liver Disease in a Murine Fast-Food Diet Model.

Bhushan B, Banerjee S, Paranjpe S, Koral K, Mars WM, Stoops JW, Orr A, Bowen WC, Locker J, Michalopoulos GK.

Hepatology. 2019 May 7. doi: 10.1002/hep.30696. [Epub ahead of print]

PMID:
31063640
6.

A Noncanonical Role for Plasminogen Activator Inhibitor Type 1 in Obesity-Induced Diabetes.

Coudriet GM, Stoops J, Orr AV, Bhushan B, Koral K, Lee S, Previte DM, Dong HH, Michalopoulos GK, Mars WM, Piganelli JD.

Am J Pathol. 2019 Jul;189(7):1413-1422. doi: 10.1016/j.ajpath.2019.04.004. Epub 2019 May 2.

PMID:
31054988
7.

NFATc1-E2F1-LMCD1-Mediated IL-33 Expression by Thrombin Is Required for Injury-Induced Neointima Formation.

Govatati S, Pichavaram P, Janjanam J, Zhang B, Singh NK, Mani AM, Traylor JG Jr, Orr AW, Rao GN.

Arterioscler Thromb Vasc Biol. 2019 Jun;39(6):1212-1226. doi: 10.1161/ATVBAHA.119.312729.

PMID:
31043075
8.

The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection.

McFarlane S, Orr A, Roberts APE, Conn KL, Iliev V, Loney C, da Silva Filipe A, Smollett K, Gu Q, Robertson N, Adams PD, Rai TS, Boutell C.

PLoS Pathog. 2019 Mar 22;15(3):e1007667. doi: 10.1371/journal.ppat.1007667. eCollection 2019 Mar.

9.

Neuronal Apolipoprotein E4 Expression Results in Proteome-Wide Alterations and Compromises Bioenergetic Capacity by Disrupting Mitochondrial Function.

Orr AL, Kim C, Jimenez-Morales D, Newton BW, Johnson JR, Krogan NJ, Swaney DL, Mahley RW.

J Alzheimers Dis. 2019;68(3):991-1011. doi: 10.3233/JAD-181184.

10.

Activation of COUP-TFI by a Novel Diindolylmethane Derivative.

Yoon K, Chen CC, Orr AA, Barreto PN, Tamamis P, Safe S.

Cells. 2019 Mar 7;8(3). pii: E220. doi: 10.3390/cells8030220.

11.

Doxorubicin-induced cardiomyopathy associated with inhibition of autophagic degradation process and defects in mitochondrial respiration.

Abdullah CS, Alam S, Aishwarya R, Miriyala S, Bhuiyan MAN, Panchatcharam M, Pattillo CB, Orr AW, Sadoshima J, Hill JA, Bhuiyan MS.

Sci Rep. 2019 Feb 14;9(1):2002. doi: 10.1038/s41598-018-37862-3.

12.

Genetic Markers of Benzimidazole Resistance among Human Hookworms (Necator americanus) in Kintampo North Municipality, Ghana.

Orr AR, Quagraine JE, Suwondo P, George S, Harrison LM, Dornas FP, Evans B, Caccone A, Humphries D, Wilson MD, Cappello M.

Am J Trop Med Hyg. 2019 Feb;100(2):351-356. doi: 10.4269/ajtmh.18-0727.

PMID:
30734697
13.

Cardiovascular disease is obNOXious: New insights into NoxA1 in smooth muscle phenotype.

Orr AW, Woolard MD.

Redox Biol. 2019 Apr;22:101081. doi: 10.1016/j.redox.2018.101081. Epub 2018 Dec 19. No abstract available.

14.

Developmental expression patterns of protein kinase A catalytic subunits in zebrafish.

Emerson SE, Grebber BK, McNellis ME, Orr AR, Deming PB, Ebert AM.

Gene Expr Patterns. 2019 Jan;31:1-6. doi: 10.1016/j.gep.2018.11.001. Epub 2018 Nov 20.

PMID:
30468770
15.

Elucidating the multi-targeted anti-amyloid activity and enhanced islet amyloid polypeptide binding of β-wrapins.

Orr AA, Shaykhalishahi H, Mirecka EA, Jonnalagadda SVR, Hoyer W, Tamamis P.

Comput Chem Eng. 2018 Aug 4;116:322-332. doi: 10.1016/j.compchemeng.2018.02.013. Epub 2018 Feb 21.

16.

Cardiac Dysfunction in the Sigma 1 Receptor Knockout Mouse Associated With Impaired Mitochondrial Dynamics and Bioenergetics.

Abdullah CS, Alam S, Aishwarya R, Miriyala S, Panchatcharam M, Bhuiyan MAN, Peretik JM, Orr AW, James J, Osinska H, Robbins J, Lorenz JN, Bhuiyan MS.

J Am Heart Assoc. 2018 Oct 16;7(20):e009775. doi: 10.1161/JAHA.118.009775.

17.

Endothelial FN (Fibronectin) Deposition by α5β1 Integrins Drives Atherogenic Inflammation.

Al-Yafeai Z, Yurdagul A Jr, Peretik JM, Alfaidi M, Murphy PA, Orr AW.

Arterioscler Thromb Vasc Biol. 2018 Nov;38(11):2601-2614. doi: 10.1161/ATVBAHA.118.311705.

PMID:
30354234
18.

Guidance Molecules in Vascular Smooth Muscle.

Finney AC, Orr AW.

Front Physiol. 2018 Sep 19;9:1311. doi: 10.3389/fphys.2018.01311. eCollection 2018. Review.

19.

Virtual Screening of Chemical Compounds for Discovery of Complement C3 Ligands.

Mohan RR, Wilson M, Gorham RD Jr, Harrison RES, Morikis VA, Kieslich CA, Orr AA, Coley AV, Tamamis P, Morikis D.

ACS Omega. 2018 Jun 30;3(6):6427-6438. doi: 10.1021/acsomega.8b00606. Epub 2018 Jun 15.

20.

Lymphocyte-Specific Protein-1 Controls Sorafenib Sensitivity and Hepatocellular Proliferation through Extracellular Signal-Regulated Kinase 1/2 Activation.

Koral K, Haynes M, Bowen WC, Orr A, Mars W, Michalopoulos GK.

Am J Pathol. 2018 Sep;188(9):2074-2086. doi: 10.1016/j.ajpath.2018.06.005. Epub 2018 Jul 3.

PMID:
30126548
21.

Gene Transfer Induced Hypercholesterolemia in Amyloid Mice.

Grames MS, Dayton RD, Lu X, Schilke RM, Alexander JS, Orr AW, Barmada SJ, Woolard MD, Klein RL.

J Alzheimers Dis. 2018;65(4):1079-1086. doi: 10.3233/JAD-180494.

PMID:
30124449
23.

Decreases in GSH:GSSG activate vascular endothelial growth factor receptor 2 (VEGFR2) in human aortic endothelial cells.

Prasai PK, Shrestha B, Orr AW, Pattillo CB.

Redox Biol. 2018 Oct;19:22-27. doi: 10.1016/j.redox.2018.07.015. Epub 2018 Jul 25.

24.

Combined Systemic Disruption of MET and Epidermal Growth Factor Receptor Signaling Causes Liver Failure in Normal Mice.

Tsagianni A, Mars WM, Bhushan B, Bowen WC, Orr A, Stoops J, Paranjpe S, Tseng GC, Liu S, Michalopoulos GK.

Am J Pathol. 2018 Oct;188(10):2223-2235. doi: 10.1016/j.ajpath.2018.06.009. Epub 2018 Jul 20.

PMID:
30031724
25.

Cystathionine γ-Lyase Modulates Flow-Dependent Vascular Remodeling.

Yuan S, Yurdagul A Jr, Peretik JM, Alfaidi M, Al Yafeai Z, Pardue S, Kevil CG, Orr AW.

Arterioscler Thromb Vasc Biol. 2018 Sep;38(9):2126-2136. doi: 10.1161/ATVBAHA.118.311402. Erratum in: Arterioscler Thromb Vasc Biol. 2019 Feb;39(2):e82.

PMID:
30002061
26.

De novo designed transmembrane peptides activating the α5β1 integrin.

Mravic M, Hu H, Lu Z, Bennett JS, Sanders CR, Orr AW, DeGrado WF.

Protein Eng Des Sel. 2018 May 1;31(5):181-190. doi: 10.1093/protein/gzy014.

27.

Aberrant Mitochondrial Fission Is Maladaptive in Desmin Mutation-Induced Cardiac Proteotoxicity.

Alam S, Abdullah CS, Aishwarya R, Miriyala S, Panchatcharam M, Peretik JM, Orr AW, James J, Robbins J, Bhuiyan MS.

J Am Heart Assoc. 2018 Jul 9;7(14). pii: e009289. doi: 10.1161/JAHA.118.009289.

28.

Computational Design of Functional Amyloid Materials with Cesium Binding, Deposition, and Capture Properties.

Jonnalagadda SVR, Kokotidou C, Orr AA, Fotopoulou E, Henderson KJ, Choi CH, Lim WT, Choi SJ, Jeong HK, Mitraki A, Tamamis P.

J Phys Chem B. 2018 Aug 2;122(30):7555-7568. doi: 10.1021/acs.jpcb.8b04103. Epub 2018 Jul 20.

PMID:
29975835
29.

Differential arterial and venous endothelial redox responses to oxidative stress.

Shrestha B, Prasai PK, Kaskas AM, Khanna A, Letchuman V, Letchuman S, Alexander JS, Orr AW, Woolard MD, Pattillo CB.

Microcirculation. 2018 Oct;25(7):e12486. doi: 10.1111/micc.12486. Epub 2018 Jul 23.

PMID:
29923664
30.

TCPOBOP-Induced Hepatomegaly and Hepatocyte Proliferation are Attenuated by Combined Disruption of MET and EGFR Signaling.

Bhushan B, Stoops JW, Mars WM, Orr A, Bowen WC, Paranjpe S, Michalopoulos GK.

Hepatology. 2019 Apr;69(4):1702-1718. doi: 10.1002/hep.30109. Epub 2018 Dec 31.

PMID:
29888801
31.

Plate-Based Measurement of Superoxide and Hydrogen Peroxide Production by Isolated Mitochondria.

Wong HS, Monternier PA, Orr AL, Brand MD.

Methods Mol Biol. 2018;1782:287-299. doi: 10.1007/978-1-4939-7831-1_16.

PMID:
29851006
32.

Extranodal Rosai-Dorfman Disease Presenting as a Mediastinal Mass with Pulmonary Artery Invasion.

Orr AR, Lefler D, Deshpande C, Kumar P.

Case Rep Hematol. 2018 Apr 12;2018:3915319. doi: 10.1155/2018/3915319. eCollection 2018.

33.

EphA2 stimulates VCAM-1 expression through calcium-dependent NFAT1 activity.

Funk SD, Finney AC, Yurdagul A Jr, Pattillo CB, Orr AW.

Cell Signal. 2018 Sep;49:30-38. doi: 10.1016/j.cellsig.2018.05.008. Epub 2018 May 21.

PMID:
29793020
34.

A novel amyloid designable scaffold and potential inhibitor inspired by GAIIG of amyloid beta and the HIV-1 V3 loop.

Kokotidou C, Jonnalagadda SVR, Orr AA, Seoane-Blanco M, Apostolidou CP, van Raaij MJ, Kotzabasaki M, Chatzoudis A, Jakubowski JM, Mossou E, Forsyth VT, Mitchell EP, Bowler MW, Llamas-Saiz AL, Tamamis P, Mitraki A.

FEBS Lett. 2018 Jun;592(11):1777-1788. doi: 10.1002/1873-3468.13096. Epub 2018 Jun 6.

35.

Structure-Dependent Modulation of Aryl Hydrocarbon Receptor-Mediated Activities by Flavonoids.

Jin UH, Park H, Li X, Davidson LA, Allred C, Patil B, Jayaprakasha G, Orr AA, Mao L, Chapkin RS, Jayaraman A, Tamamis P, Safe S.

Toxicol Sci. 2018 Jul 1;164(1):205-217. doi: 10.1093/toxsci/kfy075.

36.

Müller glia-derived PRSS56 is required to sustain ocular axial growth and prevent refractive error.

Paylakhi S, Labelle-Dumais C, Tolman NG, Sellarole MA, Seymens Y, Saunders J, Lakosha H, deVries WN, Orr AC, Topilko P, John SW, Nair KS.

PLoS Genet. 2018 Mar 12;14(3):e1007244. doi: 10.1371/journal.pgen.1007244. eCollection 2018 Mar.

37.

Correction: Distinct temporal roles for the promyelocytic leukaemia (PML) protein in the sequential regulation of intracellular host immunity to HSV-1 infection.

Alandijany T, Roberts APE, Conn KL, Loney C, McFarlane S, Orr A, Boutell C.

PLoS Pathog. 2018 Feb 22;14(2):e1006927. doi: 10.1371/journal.ppat.1006927. eCollection 2018 Feb.

38.

What Factors Lead to the Success of a Continuity Clinic Immersion Experience for Residents?

Kearns MD, Orr AR, Wang FY.

J Grad Med Educ. 2018 Feb;10(1):107. doi: 10.4300/JGME-D-17-00629.1. No abstract available.

39.

Absence of Nicotinamide Nucleotide Transhydrogenase in C57BL/6J Mice Exacerbates Experimental Atherosclerosis.

Vozenilek AE, Vetkoetter M, Green JM, Shen X, Traylor JG, Klein RL, Orr AW, Woolard MD, Krzywanski DM.

J Vasc Res. 2018;55(2):98-110. doi: 10.1159/000486337. Epub 2018 Feb 16.

40.

A critical role for both CD40 and VLA5 in angiotensin II-mediated thrombosis and inflammation.

Senchenkova EY, Russell J, Vital SA, Yildirim A, Orr AW, Granger DN, Gavins FNE.

FASEB J. 2018 Jun;32(6):3448-3456. doi: 10.1096/fj.201701068R. Epub 2018 Feb 8.

PMID:
29452567
41.

Molecular Modeling of Chemoreceptor:Ligand Interactions.

Orr AA, Jayaraman A, Tamamis P.

Methods Mol Biol. 2018;1729:353-372. doi: 10.1007/978-1-4939-7577-8_28.

PMID:
29429104
42.

A high-throughput and rapid computational method for screening of RNA post-transcriptional modifications that can be recognized by target proteins.

Orr AA, Gonzalez-Rivera JC, Wilson M, Bhikha PR, Wang D, Contreras LM, Tamamis P.

Methods. 2018 Jul 1;143:34-47. doi: 10.1016/j.ymeth.2018.01.015. Epub 2018 Feb 1.

PMID:
29408626
43.

LIM and cysteine-rich domains 1 is required for thrombin-induced smooth muscle cell proliferation and promotes atherogenesis.

Janjanam J, Zhang B, Mani AM, Singh NK, Traylor JG Jr, Orr AW, Rao GN.

J Biol Chem. 2018 Mar 2;293(9):3088-3103. doi: 10.1074/jbc.RA117.000866. Epub 2018 Jan 11.

44.

Distinct temporal roles for the promyelocytic leukaemia (PML) protein in the sequential regulation of intracellular host immunity to HSV-1 infection.

Alandijany T, Roberts APE, Conn KL, Loney C, McFarlane S, Orr A, Boutell C.

PLoS Pathog. 2018 Jan 8;14(1):e1006769. doi: 10.1371/journal.ppat.1006769. eCollection 2018 Jan. Erratum in: PLoS Pathog. 2018 Feb 22;14 (2):e1006927.

45.

<i>Oligoaeschna</i> <i>sirindhornae</i> sp. nov., a new dragonfly species from Thailand (Odonata: Anisoptera: Aeshnidae).

Ngiam RWJ, Orr AG.

Zootaxa. 2017 Nov 22;4353(1):195-200. doi: 10.11646/zootaxa.4353.1.13.

PMID:
29245533
46.

Macrophage-Associated Lipin-1 Enzymatic Activity Contributes to Modified Low-Density Lipoprotein-Induced Proinflammatory Signaling and Atherosclerosis.

Vozenilek AE, Navratil AR, Green JM, Coleman DT, Blackburn CMR, Finney AC, Pearson BH, Chrast R, Finck BN, Klein RL, Orr AW, Woolard MD.

Arterioscler Thromb Vasc Biol. 2018 Feb;38(2):324-334. doi: 10.1161/ATVBAHA.117.310455. Epub 2017 Dec 7. Erratum in: Arterioscler Thromb Vasc Biol. 2018 May;38(5):e89.

47.

A review of the occurrence and diversity of the sphragis in butterflies (Lepidoptera, Papilionoidea).

Carvalho APS, Orr AG, Kawahara AY.

Zookeys. 2017 Aug 29;(694):41-70. doi: 10.3897/zookeys.694.13097. eCollection 2017. Review.

48.

Istradefylline reduces memory deficits in aging mice with amyloid pathology.

Orr AG, Lo I, Schumacher H, Ho K, Gill M, Guo W, Kim DH, Knox A, Saito T, Saido TC, Simms J, Toddes C, Wang X, Yu GQ, Mucke L.

Neurobiol Dis. 2018 Feb;110:29-36. doi: 10.1016/j.nbd.2017.10.014. Epub 2017 Oct 31.

49.

Chronic BMY7378 treatment alters behavioral circadian rhythms.

Vijaya Shankara J, Orr A, Mychasiuk R, Antle MC.

Eur J Neurosci. 2017 Dec;46(11):2782-2790. doi: 10.1111/ejn.13744. Epub 2017 Nov 6.

PMID:
29044737
50.

Cardiac-specific inactivation of LPP3 in mice leads to myocardial dysfunction and heart failure.

Chandra M, Escalante-Alcalde D, Bhuiyan MS, Orr AW, Kevil C, Morris AJ, Nam H, Dominic P, McCarthy KJ, Miriyala S, Panchatcharam M.

Redox Biol. 2018 Apr;14:261-271. doi: 10.1016/j.redox.2017.09.015. Epub 2017 Sep 28.

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