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Items: 1 to 50 of 216

1.

Analysis of the dynamic aberrant landscape of DNA methylation and gene expression during arsenic-induced cell transformation.

Barajas-Olmos FM, Ortiz-Sánchez E, Imaz-Rosshandler I, Córdova-Alarcón EJ, Martínez-Tovar A, Villanueva-Toledo J, Morales-Marín ME, Cruz-Colín JL, Rangel C, Orozco L, Centeno F.

Gene. 2019 Jun 23;711:143941. doi: 10.1016/j.gene.2019.143941. [Epub ahead of print]

PMID:
31242453
2.

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.

Flannick J, Mercader JM, Fuchsberger C, Udler MS, Mahajan A, Wessel J, Teslovich TM, Caulkins L, Koesterer R, Barajas-Olmos F, Blackwell TW, Boerwinkle E, Brody JA, Centeno-Cruz F, Chen L, Chen S, Contreras-Cubas C, Córdova E, Correa A, Cortes M, DeFronzo RA, Dolan L, Drews KL, Elliott A, Floyd JS, Gabriel S, Garay-Sevilla ME, García-Ortiz H, Gross M, Han S, Heard-Costa NL, Jackson AU, Jørgensen ME, Kang HM, Kelsey M, Kim BJ, Koistinen HA, Kuusisto J, Leader JB, Linneberg A, Liu CT, Liu J, Lyssenko V, Manning AK, Marcketta A, Malacara-Hernandez JM, Martínez-Hernández A, Matsuo K, Mayer-Davis E, Mendoza-Caamal E, Mohlke KL, Morrison AC, Ndungu A, Ng MCY, O'Dushlaine C, Payne AJ, Pihoker C; Broad Genomics Platform, Post WS, Preuss M, Psaty BM, Vasan RS, Rayner NW, Reiner AP, Revilla-Monsalve C, Robertson NR, Santoro N, Schurmann C, So WY, Soberón X, Stringham HM, Strom TM, Tam CHT, Thameem F, Tomlinson B, Torres JM, Tracy RP, van Dam RM, Vujkovic M, Wang S, Welch RP, Witte DR, Wong TY, Atzmon G, Barzilai N, Blangero J, Bonnycastle LL, Bowden DW, Chambers JC, Chan E, Cheng CY, Cho YS, Collins FS, de Vries PS, Duggirala R, Glaser B, Gonzalez C, Gonzalez ME, Groop L, Kooner JS, Kwak SH, Laakso M, Lehman DM, Nilsson P, Spector TD, Tai ES, Tuomi T, Tuomilehto J, Wilson JG, Aguilar-Salinas CA, Bottinger E, Burke B, Carey DJ, Chan JCN, Dupuis J, Frossard P, Heckbert SR, Hwang MY, Kim YJ, Kirchner HL, Lee JY, Lee J, Loos RJF, Ma RCW, Morris AD, O'Donnell CJ, Palmer CNA, Pankow J, Park KS, Rasheed A, Saleheen D, Sim X, Small KS, Teo YY, Haiman C, Hanis CL, Henderson BE, Orozco L, Tusié-Luna T, Dewey FE, Baras A, Gieger C, Meitinger T, Strauch K, Lange L, Grarup N, Hansen T, Pedersen O, Zeitler P, Dabelea D, Abecasis G, Bell GI, Cox NJ, Seielstad M, Sladek R, Meigs JB, Rich SS, Rotter JI; DiscovEHR Collaboration; CHARGE; LuCamp; ProDiGY; GoT2D; ESP; SIGMA-T2D; T2D-GENES; AMP-T2D-GENES, Altshuler D, Burtt NP, Scott LJ, Morris AP, Florez JC, McCarthy MI, Boehnke M.

Nature. 2019 Jun;570(7759):71-76. doi: 10.1038/s41586-019-1231-2. Epub 2019 May 22.

3.

Next-generation sequencing for identifying a novel/de novo pathogenic variant in a Mexican patient with cystic fibrosis: a case report.

Martínez-Hernández A, Larrosa J, Barajas-Olmos F, García-Ortíz H, Mendoza-Caamal EC, Contreras-Cubas C, Mirzaeicheshmeh E, Lezana JL, Orozco L.

BMC Med Genomics. 2019 May 22;12(1):68. doi: 10.1186/s12920-019-0528-1.

4.

Curcumin induces p53-independent inactivation of Nrf2 during oxidative stress-induced apoptosis.

Méndez-García LA, Martínez-Castillo M, Villegas-Sepúlveda N, Orozco L, Córdova EJ.

Hum Exp Toxicol. 2019 Apr 24:960327119845035. doi: 10.1177/0960327119845035. [Epub ahead of print]

PMID:
31018701
5.

Comparing signals of natural selection between three Indigenous North American populations.

Reynolds AW, Mata-Míguez J, Miró-Herrans A, Briggs-Cloud M, Sylestine A, Barajas-Olmos F, Garcia-Ortiz H, Rzhetskaya M, Orozco L, Raff JA, Hayes MG, Bolnick DA.

Proc Natl Acad Sci U S A. 2019 May 7;116(19):9312-9317. doi: 10.1073/pnas.1819467116. Epub 2019 Apr 15.

PMID:
30988184
6.

Influence of obesity, parental history of diabetes, and genes in type 2 diabetes: A case-control study.

Berumen J, Orozco L, Betancourt-Cravioto M, Gallardo H, Zulueta M, Mendizabal L, Simon L, Benuto RE, Ramírez-Campos E, Marin M, Juárez E, García-Ortiz H, Martínez-Hernández A, Venegas-Vega C, Peralta-Romero J, Cruz M, Tapia-Conyer R.

Sci Rep. 2019 Feb 26;9(1):2748. doi: 10.1038/s41598-019-39145-x.

7.

Tuberculosis and impaired IL-23-dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variant.

Boisson-Dupuis S, Ramirez-Alejo N, Li Z, Patin E, Rao G, Kerner G, Lim CK, Krementsov DN, Hernandez N, Ma CS, Zhang Q, Markle J, Martinez-Barricarte R, Payne K, Fisch R, Deswarte C, Halpern J, Bouaziz M, Mulwa J, Sivanesan D, Lazarov T, Naves R, Garcia P, Itan Y, Boisson B, Checchi A, Jabot-Hanin F, Cobat A, Guennoun A, Jackson CC, Pekcan S, Caliskaner Z, Inostroza J, Costa-Carvalho BT, de Albuquerque JAT, Garcia-Ortiz H, Orozco L, Ozcelik T, Abid A, Rhorfi IA, Souhi H, Amrani HN, Zegmout A, Geissmann F, Michnick SW, Muller-Fleckenstein I, Fleckenstein B, Puel A, Ciancanelli MJ, Marr N, Abolhassani H, Balcells ME, Condino-Neto A, Strickler A, Abarca K, Teuscher C, Ochs HD, Reisli I, Sayar EH, El-Baghdadi J, Bustamante J, Hammarström L, Tangye SG, Pellegrini S, Quintana-Murci L, Abel L, Casanova JL.

Sci Immunol. 2018 Dec 21;3(30). pii: eaau8714. doi: 10.1126/sciimmunol.aau8714.

8.

[Programa de detección del alelo APOE-E4 en adultos mayores mexicanos con deterioro cognitivo].

Genis-Mendoza AD, Martínez-Magaña JJ, Bojórquez C, Téllez-Martínez JA, Jiménez-Genchi J, Roche A, Bojorge A, Chávez M, Castañeda C, Guzmán R, Zapata L, Aguilar-Méndez D, Lanzagorta N, Rebolledo I, Castro-Chavira S, Fernández T, Orozco L, Nicolini H, Martínez-Hernández AG.

Gac Med Mex. 2018;154(5):555-560. doi: 10.24875/GMM.18003784. Spanish.

9.

Deep Multi-OMICs and Multi-Tissue Characterization in a Pre- and Postprandial State in Human Volunteers: The GEMM Family Study Research Design.

Bastarrachea RA, Laviada-Molina HA, Nava-Gonzalez EJ, Leal-Berumen I, Escudero-Lourdes C, Escalante-Araiza F, Peschard VG, Veloz-Garza RA, Haack K, Martínez-Hernández A, Barajas-Olmos FM, Molina-Segui F, Buenfil-Rello FA, Gonzalez-Ramirez L, Janssen-Aguilar R, Lopez-Muñoz R, Perez-Cetina F, Gaytan-Saucedo JF, Vaquera Z, Cornejo-Barrera J, Castillo-Pineda JC, Murillo-Ramirez A, Diaz-Tena SP, Figueroa-Nuñez B, González-López L, Salinas-Osornio RA, Valencia-Rendón ME, Ángeles-Chimal J, Santa-Olalla Tapia J, Remes-Troche JM, Valdovinos-Chavez SB, Huerta-Avila EE, Han X, Orozco L, Rodriguez-Ayala E, Weintraub S, Gallegos-Cabrales EC, Cole SA, Kent JW Jr.

Genes (Basel). 2018 Nov 2;9(11). pii: E532. doi: 10.3390/genes9110532.

10.

Genotoxicity and cytotoxicity of three microcystin-LR containing cyanobacterial samples from Antioquia, Colombia.

Herrera N, Herrera C, Ortíz I, Orozco L, Robledo S, Agudelo D, Echeverri F.

Toxicon. 2018 Nov;154:50-59. doi: 10.1016/j.toxicon.2018.09.011. Epub 2018 Sep 28.

11.

Gene variants in AKT1, GCKR and SOCS3 are differentially associated with metabolic traits in Mexican Amerindians and Mestizos.

Cid-Soto MA, Martínez-Hernández A, García-Ortíz H, Córdova EJ, Barajas-Olmos F, Centeno-Cruz F, Contreras-Cubas C, Mendoza-Caamal EC, Ciceron-Arellano I, Morales-Rivera MI, Jimenez-Ruiz JL, Salas-Martínez G, Saldaña-Álvarez Y, Revilla-Monsalve C, Islas-Andrade S, Orozco L.

Gene. 2018 Dec 30;679:160-171. doi: 10.1016/j.gene.2018.08.076. Epub 2018 Aug 31.

PMID:
30176313
12.

Association between Vitamin D Deficiency and Single Nucleotide Polymorphisms in the Vitamin D Receptor and GC Genes and Analysis of Their Distribution in Mexican Postmenopausal Women.

Rivera-Paredez B, Macías N, Martínez-Aguilar MM, Hidalgo-Bravo A, Flores M, Quezada-Sánchez AD, Denova-Gutiérrez E, Cid M, Martínez-Hernández A, Orozco L, Quiterio M, Flores YN, Salmerón J, Velázquez-Cruz R.

Nutrients. 2018 Aug 27;10(9). pii: E1175. doi: 10.3390/nu10091175.

13.

A homozygous CEP57 c.915_925dupCAATGTTCAGC mutation in a patient with mosaic variegated aneuploidy syndrome with rhizomelic shortening in the upper and lower limbs and a narrow thorax.

De la Torre-García O, Mar-Aldama R, Salgado-Sangri R, Diaz-Gomez N, Bonilla-Arcaute L, Diaz-Ponce-Medrano J, Guevara-Yañez R, Córdova EJ, Monge-Cazares T, Orozco L, Martínez-Hernández A.

Eur J Med Genet. 2019 Mar;62(3):195-197. doi: 10.1016/j.ejmg.2018.07.013. Epub 2018 Jul 17.

PMID:
30010053
14.

Cocoa ingestion protects plasma lipids in healthy males against ex vivo oxidative conditions: A randomized clinical trial.

Barrios M, Orozco LC, Stashenko EE.

Clin Nutr ESPEN. 2018 Aug;26:1-7. doi: 10.1016/j.clnesp.2018.05.001. Epub 2018 May 30.

PMID:
29908675
15.

Epigenome-wide association in adipose tissue from the METSIM cohort.

Orozco LD, Farrell C, Hale C, Rubbi L, Rinaldi A, Civelek M, Pan C, Lam L, Montoya D, Edillor C, Seldin M, Boehnke M, Mohlke KL, Jacobsen S, Kuusisto J, Laakso M, Lusis AJ, Pellegrini M.

Hum Mol Genet. 2018 Jul 15;27(14):2586. doi: 10.1093/hmg/ddy205. No abstract available.

16.

Drivers of flea (Siphonaptera) community structure in sympatric wild carnivores in northwestern Mexico.

López-Pérez AM, Gage K, Rubio AV, Montenieri J, Orozco L, Suzan G.

J Vector Ecol. 2018 Jun;43(1):15-25. doi: 10.1111/jvec.12278.

17.

Influence of SNPs in Genes that Modulate Lung Disease Severity in a Group of Mexican Patients with Cystic Fibrosis.

Yokoyama E, Chávez-Saldaña M, Orozco L, Cuevas F, Lezana JL, Vigueras-Villaseñor RM, Rojas-Castañeda JC, Landero DA.

Arch Med Res. 2018 Jan;49(1):18-26. doi: 10.1016/j.arcmed.2018.04.010. Epub 2018 Apr 24.

PMID:
29703608
18.

Curcumin differentially affects cell cycle and cell death in acute and chronic myeloid leukemia cells.

Martínez-Castillo M, Villegas-Sepúlveda N, Meraz-Rios MA, Hernández-Zavala A, Berumen J, Coleman MA, Orozco L, Cordova EJ.

Oncol Lett. 2018 May;15(5):6777-6783. doi: 10.3892/ol.2018.8112. Epub 2018 Feb 23.

19.

Spin-optomechanical coupling between light and a nanofiber torsional mode.

Fenton EF, Khan A, Solano P, Orozco LA, Fatemi FK.

Opt Lett. 2018 Apr 1;43(7):1534-1537. doi: 10.1364/OL.43.001534.

PMID:
29601023
20.

Epigenome-wide association in adipose tissue from the METSIM cohort.

Orozco LD, Farrell C, Hale C, Rubbi L, Rinaldi A, Civelek M, Pan C, Lam L, Montoya D, Edillor C, Seldin M, Boehnke M, Mohlke KL, Jacobsen S, Kuusisto J, Laakso M, Lusis AJ, Pellegrini M.

Hum Mol Genet. 2018 May 15;27(10):1830-1846. doi: 10.1093/hmg/ddy093. Erratum in: Hum Mol Genet. 2018 Jul 15;27(14):2586.

21.

Altered DNA methylation in liver and adipose tissues derived from individuals with obesity and type 2 diabetes.

Barajas-Olmos F, Centeno-Cruz F, Zerrweck C, Imaz-Rosshandler I, Martínez-Hernández A, Cordova EJ, Rangel-Escareño C, Gálvez F, Castillo A, Maydón H, Campos F, Maldonado-Pintado DG, Orozco L.

BMC Med Genet. 2018 Feb 21;19(1):28. doi: 10.1186/s12881-018-0542-8.

22.

Trypanosoma cruzi Detection in Colombian Patients with a Diagnosis of Esophageal Achalasia.

Panesso-Gómez S, Pavia P, Rodríguez-Mantilla IE, Lasso P, Orozco LA, Cuellar A, Puerta CJ, Mendoza de Molano B, González JM.

Am J Trop Med Hyg. 2018 Mar;98(3):717-723. doi: 10.4269/ajtmh.17-0417. Epub 2018 Feb 1.

23.

Super-radiance reveals infinite-range dipole interactions through a nanofiber.

Solano P, Barberis-Blostein P, Fatemi FK, Orozco LA, Rolston SL.

Nat Commun. 2017 Nov 30;8(1):1857. doi: 10.1038/s41467-017-01994-3.

24.

GSTT1 and GSTM1 null variants in Mestizo and Amerindian populations from northwestern Mexico and a literature review.

Palma-Cano LE, Córdova EJ, Orozco L, Martínez-Hernández A, Cid M, Leal-Berumen I, Licón-Trillo A, Lechuga-Valles R, González-Ponce M, González-Rodríguez E, Moreno-Brito V.

Genet Mol Biol. 2017 Oct-Dec;40(4):727-735. doi: 10.1590/1678-4685-GMB-2016-0142. Epub 2017 Nov 6.

25.

Origin of the myotonic dystrophy type 1 mutation in Mexican population and influence of Amerindian ancestry on CTG repeat allelic distribution.

Murillo-Melo NM, Márquez-Quiróz LC, Gómez R, Orozco L, Mendoza-Caamal E, Tapia-Guerrero YS, Camacho-Mejorado R, Cortés H, López-Reyes A, Santana C, Noris G, Hernández-Hernández O, Cisneros B, Magaña JJ.

Neuromuscul Disord. 2017 Dec;27(12):1106-1114. doi: 10.1016/j.nmd.2017.09.004. Epub 2017 Sep 21.

PMID:
29054426
26.

Demographic history and biologically relevant genetic variation of Native Mexicans inferred from whole-genome sequencing.

Romero-Hidalgo S, Ochoa-Leyva A, Garcíarrubio A, Acuña-Alonzo V, Antúnez-Argüelles E, Balcazar-Quintero M, Barquera-Lozano R, Carnevale A, Cornejo-Granados F, Fernández-López JC, García-Herrera R, García-Ortíz H, Granados-Silvestre Á, Granados J, Guerrero-Romero F, Hernández-Lemus E, León-Mimila P, Macín-Pérez G, Martínez-Hernández A, Menjivar M, Morett E, Orozco L, Ortíz-López G, Pérez-Villatoro F, Rivera-Morales J, Riveros-McKay F, Villalobos-Comparán M, Villamil-Ramírez H, Villarreal-Molina T, Canizales-Quinteros S, Soberón X.

Nat Commun. 2017 Oct 18;8(1):1005. doi: 10.1038/s41467-017-01194-z.

27.

[Mutagenicity, genotoxicity and gene expression of Rad51C, Xiap, P53 and Nrf2 induced by antimalarial extracts of plants collected from the middle Vaupés region, Colombia].

Barbosa CV, Muskus CE, Orozco LY, Pabón A.

Biomedica. 2017 Sep 1;37(3):378-389. doi: 10.7705/biomedica.v37i3.3239. Spanish.

28.

A homozygous mutation in the PSMB8 gene in a case with proteasome-associated autoinflammatory syndrome.

Contreras-Cubas C, Cárdenas-Conejo A, Rodríguez-Velasco A, García-Ortiz H, Orozco L, Baca V.

Scand J Rheumatol. 2018 May;47(3):251-254. doi: 10.1080/03009742.2017.1342273. Epub 2017 Sep 12. No abstract available.

PMID:
28895430
29.

A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes.

Mercader JM, Liao RG, Bell AD, Dymek Z, Estrada K, Tukiainen T, Huerta-Chagoya A, Moreno-Macías H, Jablonski KA, Hanson RL, Walford GA, Moran I, Chen L, Agarwala V, Ordoñez-Sánchez ML, Rodríguez-Guillen R, Rodríguez-Torres M, Segura-Kato Y, García-Ortiz H, Centeno-Cruz F, Barajas-Olmos F, Caulkins L, Puppala S, Fontanillas P, Williams AL, Bonàs-Guarch S, Hartl C, Ripke S; Diabetes Prevention Program Research Group, Tooley K, Lane J, Zerrweck C, Martínez-Hernández A, Córdova EJ, Mendoza-Caamal E, Contreras-Cubas C, González-Villalpando ME, Cruz-Bautista I, Muñoz-Hernández L, Gómez-Velasco D, Alvirde U, Henderson BE, Wilkens LR, Le Marchand L, Arellano-Campos O, Riba L, Harden M; Broad Genomics Platform, Gabriel S; T2D-GENES Consortium, Abboud HE, Cortes ML, Revilla-Monsalve C, Islas-Andrade S, Soberon X, Curran JE, Jenkinson CP, DeFronzo RA, Lehman DM, Hanis CL, Bell GI, Boehnke M, Blangero J, Duggirala R, Saxena R, MacArthur D, Ferrer J, McCarroll SA, Torrents D, Knowler WC, Baier LJ, Burtt N, González-Villalpando C, Haiman CA, Aguilar-Salinas CA, Tusié-Luna T, Flannick J, Jacobs SBR, Orozco L, Altshuler D, Florez JC; SIGMA T2D Genetics Consortium.

Diabetes. 2017 Nov;66(11):2903-2914. doi: 10.2337/db17-0187. Epub 2017 Aug 24.

30.

Transancestral mapping and genetic load in systemic lupus erythematosus.

Langefeld CD, Ainsworth HC, Cunninghame Graham DS, Kelly JA, Comeau ME, Marion MC, Howard TD, Ramos PS, Croker JA, Morris DL, Sandling JK, Almlöf JC, Acevedo-Vásquez EM, Alarcón GS, Babini AM, Baca V, Bengtsson AA, Berbotto GA, Bijl M, Brown EE, Brunner HI, Cardiel MH, Catoggio L, Cervera R, Cucho-Venegas JM, Dahlqvist SR, D'Alfonso S, Da Silva BM, de la Rúa Figueroa I, Doria A, Edberg JC, Endreffy E, Esquivel-Valerio JA, Fortin PR, Freedman BI, Frostegård J, García MA, de la Torre IG, Gilkeson GS, Gladman DD, Gunnarsson I, Guthridge JM, Huggins JL, James JA, Kallenberg CGM, Kamen DL, Karp DR, Kaufman KM, Kottyan LC, Kovács L, Laustrup H, Lauwerys BR, Li QZ, Maradiaga-Ceceña MA, Martín J, McCune JM, McWilliams DR, Merrill JT, Miranda P, Moctezuma JF, Nath SK, Niewold TB, Orozco L, Ortego-Centeno N, Petri M, Pineau CA, Pons-Estel BA, Pope J, Raj P, Ramsey-Goldman R, Reveille JD, Russell LP, Sabio JM, Aguilar-Salinas CA, Scherbarth HR, Scorza R, Seldin MF, Sjöwall C, Svenungsson E, Thompson SD, Toloza SMA, Truedsson L, Tusié-Luna T, Vasconcelos C, Vilá LM, Wallace DJ, Weisman MH, Wither JE, Bhangale T, Oksenberg JR, Rioux JD, Gregersen PK, Syvänen AC, Rönnblom L, Criswell LA, Jacob CO, Sivils KL, Tsao BP, Schanberg LE, Behrens TW, Silverman ED, Alarcón-Riquelme ME, Kimberly RP, Harley JB, Wakeland EK, Graham RR, Gaffney PM, Vyse TJ.

Nat Commun. 2017 Jul 17;8:16021. doi: 10.1038/ncomms16021.

31.

Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms.

Rusu V, Hoch E, Mercader JM, Tenen DE, Gymrek M, Hartigan CR, DeRan M, von Grotthuss M, Fontanillas P, Spooner A, Guzman G, Deik AA, Pierce KA, Dennis C, Clish CB, Carr SA, Wagner BK, Schenone M, Ng MCY, Chen BH; MEDIA Consortium; SIGMA T2D Consortium, Centeno-Cruz F, Zerrweck C, Orozco L, Altshuler DM, Schreiber SL, Florez JC, Jacobs SBR, Lander ES.

Cell. 2017 Jun 29;170(1):199-212.e20. doi: 10.1016/j.cell.2017.06.011.

32.

Dynamics of trapped atoms around an optical nanofiber probed through polarimetry.

Solano P, Fatemi FK, Orozco LA, Rolston SL.

Opt Lett. 2017 Jun 15;42(12):2283-2286. doi: 10.1364/OL.42.002283.

PMID:
28614332
33.

Cost-Utility Analysis of Reconstruction Compared With Primary Amputation for Patients With Severe Lower Limb Trauma in Colombia.

Ceballos M, Valderrama CO, Orozco LE, Sánchez L, Valderrama JP, Lugo LH.

J Orthop Trauma. 2017 Sep;31(9):e288-e294. doi: 10.1097/BOT.0000000000000883.

PMID:
28538287
34.

Correction: ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans.

Lyons JJ, Liu Y, Ma CA, Yu X, O'Connell MP, Lawrence MG, Zhang Y, Karpe K, Zhao M, Siegel AM, Stone KD, Nelson C, Jones N, DiMaggio T, Darnell DN, Mendoza-Caamal E, Orozco L, Hughes JD, McElwee J, Hohman RJ, Frischmeyer-Guerrerio PA, Rothenberg ME, Freeman AF, Holland SM, Milner JD.

J Exp Med. 2017 Apr 3;214(4):1201. doi: 10.1084/jem.2016143503082017c. Epub 2017 Mar 13. No abstract available.

35.

Altered methylation of specific DNA loci in the liver of Bhmt-null mice results in repression of Iqgap2 and F2rl2 and is associated with development of preneoplastic foci.

Lupu DS, Orozco LD, Wang Y, Cullen JM, Pellegrini M, Zeisel SH.

FASEB J. 2017 May;31(5):2090-2103. doi: 10.1096/fj.201601169R. Epub 2017 Feb 8.

36.

ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans.

Lyons JJ, Liu Y, Ma CA, Yu X, O'Connell MP, Lawrence MG, Zhang Y, Karpe K, Zhao M, Siegel AM, Stone KD, Nelson C, Jones N, DiMaggio T, Darnell DN, Mendoza-Caamal E, Orozco L, Hughes JD, McElwee J, Hohman RJ, Frischmeyer-Guerrerio PA, Rothenberg ME, Freeman AF, Holland SM, Milner JD.

J Exp Med. 2017 Mar 6;214(3):669-680. doi: 10.1084/jem.20161435. Epub 2017 Jan 26. Erratum in: J Exp Med. 2017 Apr 3;214(4):1201.

37.

Cost-Effectiveness Analysis of the Use of a Prophylactic Antibiotic for Patients Undergoing Lower Limb Amputation due to Diabetes or Vascular Illness in Colombia.

Ceballos M, Orozco LE, Valderrama CO, Londoño DI, Lugo LH.

Ann Vasc Surg. 2017 Apr;40:327-334. doi: 10.1016/j.avsg.2016.07.090. Epub 2016 Nov 27. Review.

PMID:
27903479
38.

A transcriptome-based model of central memory CD4 T cell death in HIV infection.

Olvera-García G, Aguilar-García T, Gutiérrez-Jasso F, Imaz-Rosshandler I, Rangel-Escareño C, Orozco L, Aguilar-Delfín I, Vázquez-Pérez JA, Zúñiga J, Pérez-Patrigeon S, Espinosa E.

BMC Genomics. 2016 Nov 22;17(1):956.

39.

A Subpopulation of the K562 Cells Are Killed by Curcumin Treatment after G2/M Arrest and Mitotic Catastrophe.

Martinez-Castillo M, Bonilla-Moreno R, Aleman-Lazarini L, Meraz-Rios MA, Orozco L, Cedillo-Barron L, Cordova EJ, Villegas-Sepulveda N.

PLoS One. 2016 Nov 10;11(11):e0165971. doi: 10.1371/journal.pone.0165971. eCollection 2016.

40.

Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems.

Shu L, Zhao Y, Kurt Z, Byars SG, Tukiainen T, Kettunen J, Orozco LD, Pellegrini M, Lusis AJ, Ripatti S, Zhang B, Inouye M, Mäkinen VP, Yang X.

BMC Genomics. 2016 Nov 4;17(1):874.

41.

Pro-adhesive phenotype of normal endothelial cells responding to metastatic breast cancer cell conditioned medium is linked to NFκB-mediated transcriptomic regulation.

Mejía-Rangel J, Córdova E, Orozco L, Ventura-Gallegos JL, Mitre-Aguilar I, Escalona-Guzmán A, Vadillo F, Vázquez-Prado J, Gariglio P, Zentella-Dehesa A.

Int J Oncol. 2016 Nov;49(5):2173-2185. doi: 10.3892/ijo.2016.3705. Epub 2016 Sep 26.

PMID:
27666521
42.

Heterogenous Distribution of MTHFR Gene Variants among Mestizos and Diverse Amerindian Groups from Mexico.

Contreras-Cubas C, Sánchez-Hernández BE, García-Ortiz H, Martínez-Hernández A, Barajas-Olmos F, Cid M, Mendoza-Caamal EC, Centeno-Cruz F, Ortiz-Cruz G, Jiménez-López JC, Córdova EJ, Salas-Bautista EG, Saldaña-Alvarez Y, Fernández-López JC, Mutchinick OM, Orozco L.

PLoS One. 2016 Sep 20;11(9):e0163248. doi: 10.1371/journal.pone.0163248. eCollection 2016.

43.

Carbon-Carbon Bond Formation and Hydrogen Production in the Ketonization of Aldehydes.

Orozco LM, Renz M, Corma A.

ChemSusChem. 2016 Sep 8;9(17):2430-42. doi: 10.1002/cssc.201600654. Epub 2016 Aug 19.

PMID:
27539722
44.

Analysis of protein-coding genetic variation in 60,706 humans.

Lek M, Karczewski KJ, Minikel EV, Samocha KE, Banks E, Fennell T, O'Donnell-Luria AH, Ware JS, Hill AJ, Cummings BB, Tukiainen T, Birnbaum DP, Kosmicki JA, Duncan LE, Estrada K, Zhao F, Zou J, Pierce-Hoffman E, Berghout J, Cooper DN, Deflaux N, DePristo M, Do R, Flannick J, Fromer M, Gauthier L, Goldstein J, Gupta N, Howrigan D, Kiezun A, Kurki MI, Moonshine AL, Natarajan P, Orozco L, Peloso GM, Poplin R, Rivas MA, Ruano-Rubio V, Rose SA, Ruderfer DM, Shakir K, Stenson PD, Stevens C, Thomas BP, Tiao G, Tusie-Luna MT, Weisburd B, Won HH, Yu D, Altshuler DM, Ardissino D, Boehnke M, Danesh J, Donnelly S, Elosua R, Florez JC, Gabriel SB, Getz G, Glatt SJ, Hultman CM, Kathiresan S, Laakso M, McCarroll S, McCarthy MI, McGovern D, McPherson R, Neale BM, Palotie A, Purcell SM, Saleheen D, Scharf JM, Sklar P, Sullivan PF, Tuomilehto J, Tsuang MT, Watkins HC, Wilson JG, Daly MJ, MacArthur DG; Exome Aggregation Consortium.

Nature. 2016 Aug 18;536(7616):285-91. doi: 10.1038/nature19057.

45.

Systems Nutrigenomics Reveals Brain Gene Networks Linking Metabolic and Brain Disorders.

Meng Q, Ying Z, Noble E, Zhao Y, Agrawal R, Mikhail A, Zhuang Y, Tyagi E, Zhang Q, Lee JH, Morselli M, Orozco L, Guo W, Kilts TM, Zhu J, Zhang B, Pellegrini M, Xiao X, Young MF, Gomez-Pinilla F, Yang X.

EBioMedicine. 2016 May;7:157-66. doi: 10.1016/j.ebiom.2016.04.008. Epub 2016 Apr 13.

46.

The rs61764370 Functional Variant in the KRAS Oncogene is Associated with Chronic Myeloid Leukemia Risk in Women.

Gutiérrez-Malacatt H, Ayala-Sanchez M, Aquino-Ortega X, Dominguez-Rodriguez J, Martinez-Tovar A, Olarte-Carrillo I, Martinez-Hernandez A, C CC, Orozco L, Cordova EJ.

Asian Pac J Cancer Prev. 2016;17(4):2265-70.

47.

Transcriptome landmarks of the functional maturity of rat beta-cells, from lactation to adulthood.

Larqué C, Velasco M, Barajas-Olmos F, García-Delgado N, Chávez-Maldonado JP, García-Morales J, Orozco L, Hiriart M.

J Mol Endocrinol. 2016 Jul;57(1):45-59. doi: 10.1530/JME-16-0052. Epub 2016 May 24.

PMID:
27220619
48.

Correction: Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains.

Bennett BJ, Davis RC, Civelek M, Orozco L, Wu J, Qi H, Pan C, Sevag Packard RR, Eskin E, Yan M, Kirchgessner T, Wang Z, Li X, Gregory JC, Hazen SL, Gargalovic PS, Lusis AJ.

PLoS Genet. 2016 Mar 2;12(3):e1005913. doi: 10.1371/journal.pgen.1005913. eCollection 2016 Mar. No abstract available.

49.

DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States.

Chen H, Orozco LD, Wang J, Rau CD, Rubbi L, Ren S, Wang Y, Pellegrini M, Lusis AJ, Vondriska TM.

Circ Res. 2016 Mar 4;118(5):786-97. doi: 10.1161/CIRCRESAHA.115.305298. Epub 2016 Jan 11.

50.

Application of the micronucleus test and comet assay in Trachemys callirostris erythrocytes as a model for in situ genotoxic monitoring.

Zapata LM, Bock BC, Orozco LY, Palacio JA.

Ecotoxicol Environ Saf. 2016 May;127:108-16. doi: 10.1016/j.ecoenv.2016.01.016. Epub 2016 Jan 22.

PMID:
26809080

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