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Items: 13


A polyomavirus peptide binds to the capsid VP1 pore and has potent antiviral activity against BK and JC polyomaviruses.

Kane JR, Fong S, Shaul J, Frommlet A, Frank AO, Knapp M, Bussiere DE, Kim P, Ornelas E, Cuellar C, Hyrina A, Abend JR, Wartchow CA.

Elife. 2020 Jan 21;9. pii: e50722. doi: 10.7554/eLife.50722.


Drug reaction with eosinophilia and systemic symptoms syndrome in a patient taking lamotrigine.

Lameiras C, Ornelas É, Mendes Lopes M, Dória MDC.

BMJ Case Rep. 2019 Oct 25;12(10). pii: e229180. doi: 10.1136/bcr-2019-229180.


Effects of Physical Training on the Myocardium of Oxariectomized LDLr Knockout Mice: MMP 2/9, Collagen I/III, Inflammation and Oxidative Stress.

Brianezi L, Ornelas E, Gehrke FS, Fonseca FLA, Alves BDCA, Sousa LVA, Souza J, Maifrino LBM.

Arq Bras Cardiol. 2019 Oct 21. pii: S0066-782X2019005002002. doi: 10.5935/abc.20190223. [Epub ahead of print] English, Portuguese.


Harnessing the anti-cancer natural product nimbolide for targeted protein degradation.

Spradlin JN, Hu X, Ward CC, Brittain SM, Jones MD, Ou L, To M, Proudfoot A, Ornelas E, Woldegiorgis M, Olzmann JA, Bussiere DE, Thomas JR, Tallarico JA, McKenna JM, Schirle M, Maimone TJ, Nomura DK.

Nat Chem Biol. 2019 Jul;15(7):747-755. doi: 10.1038/s41589-019-0304-8. Epub 2019 Jun 17.


Derivation and external validation of the SHIeLD score for predicting outcome in normotensive pulmonary embolism.

Freitas P, Santos AR, Ferreira AM, Oliveira A, Gonçalves M, Corte-Real A, Lameiras C, Maurício J, Ornelas É, Matos C, Faria D, Augusto J, Simões J, Ferreira I, Pedroso A, Santos AC, Gago M, Oliveira JD, Antunes RM, Correia D, Lynce A, Brito J, Aguiar C, Ferreira J, Morais C, Campos L, Raposo L, Mendes M.

Int J Cardiol. 2019 Apr 15;281:119-124. doi: 10.1016/j.ijcard.2018.12.062. Epub 2018 Dec 28.


Massive coronary air embolism after CT-guided lung needle biopsy.

Ornelas E, Fernandez-Vilches S, Gallardo X, Mesquida J.

Intensive Care Med. 2018 Oct;44(10):1748-1749. doi: 10.1007/s00134-018-5165-1. Epub 2018 May 10. No abstract available.


Rationally Designed PI3Kα Mutants to Mimic ATR and Their Use to Understand Binding Specificity of ATR Inhibitors.

Lu Y, Knapp M, Crawford K, Warne R, Elling R, Yan K, Doyle M, Pardee G, Zhang L, Ma S, Mamo M, Ornelas E, Pan Y, Bussiere D, Jansen J, Zaror I, Lai A, Barsanti P, Sim J.

J Mol Biol. 2017 Jun 2;429(11):1684-1704. doi: 10.1016/j.jmb.2017.04.006. Epub 2017 Apr 20.


Morphological and Biochemical Effects on the Skeletal Muscle of Ovariectomized Old Female Rats Submitted to the Intake of Diets with Vegetable or Animal Protein and Resistance Training.

Figueiredo Braggion G, Ornelas E, Carmona Sattin Cury J, Edviges Alves Lima N, Aquino RC, Affonso Fonseca FL, Maifrino LB.

Oxid Med Cell Longev. 2016;2016:9251064. doi: 10.1155/2016/9251064. Epub 2016 Jan 14.


Effect of different exercise intensities on the pancreas of animals with metabolic syndrome.

Amaral F, Lima NE, Ornelas E, Simardi L, Fonseca FL, Maifrino LB.

Diabetes Metab Syndr Obes. 2015 Feb 13;8:115-20. doi: 10.2147/DMSO.S74436. eCollection 2015.


Novel potent and selective inhibitors of p90 ribosomal S6 kinase reveal the heterogeneity of RSK function in MAPK-driven cancers.

Aronchik I, Appleton BA, Basham SE, Crawford K, Del Rosario M, Doyle LV, Estacio WF, Lan J, Lindvall MK, Luu CA, Ornelas E, Venetsanakos E, Shafer CM, Jefferson AB.

Mol Cancer Res. 2014 May;12(5):803-12. doi: 10.1158/1541-7786.MCR-13-0595. Epub 2014 Feb 19.


2-Amino-7-substituted benzoxazole analogs as potent RSK2 inhibitors.

Costales A, Mathur M, Ramurthy S, Lan J, Subramanian S, Jain R, Atallah G, Setti L, Lindvall M, Appleton BA, Ornelas E, Feucht P, Warne B, Doyle L, Basham SE, Aronchik I, Jefferson AB, Shafer CM.

Bioorg Med Chem Lett. 2014 Mar 15;24(6):1592-6. doi: 10.1016/j.bmcl.2014.01.058. Epub 2014 Jan 30.


Identification and structure-activity relationship of 2-morpholino 6-(3-hydroxyphenyl) pyrimidines, a class of potent and selective PI3 kinase inhibitors.

Pecchi S, Renhowe PA, Taylor C, Kaufman S, Merritt H, Wiesmann M, Shoemaker KR, Knapp MS, Ornelas E, Hendrickson TF, Fantl W, Voliva CF.

Bioorg Med Chem Lett. 2010 Dec 1;20(23):6895-8. doi: 10.1016/j.bmcl.2010.10.021. Epub 2010 Oct 13.


Failure to induce allergic response in guinea pigs with scorpion venom.


J Allergy. 1957 Nov;28(6):540-1. No abstract available.


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