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Items: 13

1.

Epigenetic silencing of SOCS5 potentiates JAK-STAT signaling and progression of T-cell acute lymphoblastic leukemia.

Sharma ND, Nickl CK, Kang H, Ornatowski W, Brown R, Ness SA, Loh ML, Mullighan CG, Winter SS, Hunger SP, Cannon JL, Matlawska-Wasowska K.

Cancer Sci. 2019 Jun;110(6):1931-1946. doi: 10.1111/cas.14021. Epub 2019 May 3.

2.

Biomechanical Forces and Oxidative Stress: Implications for Pulmonary Vascular Disease.

Zemskov EA, Lu Q, Ornatowski W, Klinger CN, Desai AA, Maltepe E, Yuan JX, Wang T, Fineman JR, Black SM.

Antioxid Redox Signal. 2019 Oct 20;31(12):819-842. doi: 10.1089/ars.2018.7720. Epub 2019 Mar 19.

PMID:
30623676
3.

TBK-1 promotes autophagy-mediated antimicrobial defense by controlling autophagosome maturation.

Pilli M, Arko-Mensah J, Ponpuak M, Roberts E, Master S, Mandell MA, Dupont N, Ornatowski W, Jiang S, Bradfute SB, Bruun JA, Hansen TE, Johansen T, Deretic V.

Immunity. 2012 Aug 24;37(2):223-34. doi: 10.1016/j.immuni.2012.04.015.

4.

Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β.

Dupont N, Jiang S, Pilli M, Ornatowski W, Bhattacharya D, Deretic V.

EMBO J. 2011 Nov 8;30(23):4701-11. doi: 10.1038/emboj.2011.398.

5.

Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria.

Singh SB, Ornatowski W, Vergne I, Naylor J, Delgado M, Roberts E, Ponpuak M, Master S, Pilli M, White E, Komatsu M, Deretic V.

Nat Cell Biol. 2010 Dec;12(12):1154-65. doi: 10.1038/ncb2119. Epub 2010 Nov 21.

6.

Autophagy and pattern recognition receptors in innate immunity.

Delgado M, Singh S, De Haro S, Master S, Ponpuak M, Dinkins C, Ornatowski W, Vergne I, Deretic V.

Immunol Rev. 2009 Jan;227(1):189-202. doi: 10.1111/j.1600-065X.2008.00725.x. Review.

7.

Elevated furin levels in human cystic fibrosis cells result in hypersusceptibility to exotoxin A-induced cytotoxicity.

Ornatowski W, Poschet JF, Perkett E, Taylor-Cousar JL, Deretic V.

J Clin Invest. 2007 Nov;117(11):3489-97.

8.

Pharmacological modulation of cGMP levels by phosphodiesterase 5 inhibitors as a therapeutic strategy for treatment of respiratory pathology in cystic fibrosis.

Poschet JF, Timmins GS, Taylor-Cousar JL, Ornatowski W, Fazio J, Perkett E, Wilson KR, Yu HD, de Jonge HR, Deretic V.

Am J Physiol Lung Cell Mol Physiol. 2007 Sep;293(3):L712-9. Epub 2007 Jun 22.

9.

Nitrosative stress inhibits production of the virulence factor alginate in mucoid Pseudomonas aeruginosa.

Wood SR, Firoved AM, Ornatowski W, Mai T, Deretic V, Timmins GS.

Free Radic Res. 2007 Feb;41(2):208-15.

PMID:
17364947
10.

Chloroquine normalizes aberrant transforming growth factor beta activity in cystic fibrosis bronchial epithelial cells.

Perkett EA, Ornatowski W, Poschet JF, Deretic V.

Pediatr Pulmonol. 2006 Aug;41(8):771-8.

PMID:
16779853
11.

Endosomal hyperacidification in cystic fibrosis is due to defective nitric oxide-cylic GMP signalling cascade.

Poschet JF, Fazio JA, Timmins GS, Ornatowski W, Perkett E, Delgado M, Deretic V.

EMBO Rep. 2006 May;7(5):553-9. Epub 2006 Apr 13.

13.

Microarray analysis and functional characterization of the nitrosative stress response in nonmucoid and mucoid Pseudomonas aeruginosa.

Firoved AM, Wood SR, Ornatowski W, Deretic V, Timmins GS.

J Bacteriol. 2004 Jun;186(12):4046-50.

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