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A pilot study of vicarious trauma in sexual health clinicians.

Scrivener J, Orme J, Richardson D.

Int J STD AIDS. 2019 Oct;30(12):1216-1217. doi: 10.1177/0956462419860292. No abstract available.


Impact of Critical Illness on Resource Utilization: A Comparison of Use in the Year Before and After ICU Admission.

Hirshberg EL, Wilson EL, Stanfield V, Kuttler KG, Majercik S, Beesley SJ, Orme J, Hopkins RO, Brown SM.

Crit Care Med. 2019 Nov;47(11):1497-1504. doi: 10.1097/CCM.0000000000003970.


Pneumatic Compression in Venous Thromboprophylaxis.

Elliott CG, Orme J Jr, Weaver LK.

N Engl J Med. 2019 Jul 4;381(1):94. doi: 10.1056/NEJMc1905933. No abstract available.


Percentage of Time in Range 70 to 139 mg/dL Is Associated With Reduced Mortality Among Critically Ill Patients Receiving IV Insulin Infusion.

Lanspa MJ, Krinsley JS, Hersh AM, Wilson EL, Holmen JR, Orme JF, Morris AH, Hirshberg EL.

Chest. 2019 Nov;156(5):878-886. doi: 10.1016/j.chest.2019.05.016. Epub 2019 Jun 12.


Moving Health Upstream in Urban Development: Reflections on the Operationalization of a Transdisciplinary Case Study.

Black D, Scally G, Orme J, Hunt A, Pilkington P, Lawrence R, Ebi K.

Glob Chall. 2018 Aug 7;3(4):1700103. doi: 10.1002/gch2.201700103. eCollection 2019 Apr.


Positioning High-Throughput CETSA in Early Drug Discovery through Screening against B-Raf and PARP1.

Shaw J, Dale I, Hemsley P, Leach L, Dekki N, Orme JP, Talbot V, Narvaez AJ, Bista M, Martinez Molina D, Dabrowski M, Main MJ, Gianni D.

SLAS Discov. 2019 Feb;24(2):121-132. doi: 10.1177/2472555218813332. Epub 2018 Dec 13.


Randomized Feasibility Trial of a Low Tidal Volume-Airway Pressure Release Ventilation Protocol Compared With Traditional Airway Pressure Release Ventilation and Volume Control Ventilation Protocols.

Hirshberg EL, Lanspa MJ, Peterson J, Carpenter L, Wilson EL, Brown SM, Dean NC, Orme J, Grissom CK.

Crit Care Med. 2018 Dec;46(12):1943-1952. doi: 10.1097/CCM.0000000000003437.


Preliminary Validation of the Montreal Cognitive Assessment Tool among Sepsis Survivors: A Prospective Pilot Study.

Brown SM, Collingridge DS, Wilson EL, Beesley S, Bose S, Orme J, Jackson J, Hopkins RO.

Ann Am Thorac Soc. 2018 Sep;15(9):1108-1110. doi: 10.1513/AnnalsATS.201804-233OC. No abstract available.


The relationship between buildings and health: a systematic review.

Ige J, Pilkington P, Orme J, Williams B, Prestwood E, Black D, Carmichael L, Scally G.

J Public Health (Oxf). 2019 Jun 1;41(2):e121-e132. doi: 10.1093/pubmed/fdy138.


59-Year-Old Man With Fatigue, Weight Loss, and Hepatomegaly.

Orme JJ, Sidana S, Gonsalves WI.

Mayo Clin Proc. 2018 Oct;93(10):1525-1529. doi: 10.1016/j.mayocp.2017.12.028. Epub 2018 Aug 10. No abstract available.


The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models.

Durant ST, Zheng L, Wang Y, Chen K, Zhang L, Zhang T, Yang Z, Riches L, Trinidad AG, Fok JHL, Hunt T, Pike KG, Wilson J, Smith A, Colclough N, Reddy VP, Sykes A, Janefeldt A, Johnström P, Varnäs K, Takano A, Ling S, Orme J, Stott J, Roberts C, Barrett I, Jones G, Roudier M, Pierce A, Allen J, Kahn J, Sule A, Karlin J, Cronin A, Chapman M, Valerie K, Illingworth R, Pass M.

Sci Adv. 2018 Jun 20;4(6):eaat1719. doi: 10.1126/sciadv.aat1719. eCollection 2018 Jun.


The authors reply.

Beesley SJ, Hopkins RO, Holt-Lunstad J, Wilson EL, Butler J, Kuttler KG, Orme J, Brown SM, Hirshberg EL.

Crit Care Med. 2018 Jun;46(6):e625. doi: 10.1097/CCM.0000000000003098. No abstract available.


Employability and career experiences of international graduates of MSc Public Health: a mixed methods study.

Buunaaisie C, Manyara AM, Annett H, Bird EL, Bray I, Ige J, Jones M, Orme J, Pilkington P, Evans D.

Public Health. 2018 Jul;160:62-69. doi: 10.1016/j.puhe.2018.03.032. Epub 2018 May 16.


Lower Glucose Target Is Associated With Improved 30-Day Mortality in Cardiac and Cardiothoracic Patients.

Hersh AM, Hirshberg EL, Wilson EL, Orme JF, Morris AH, Lanspa MJ.

Chest. 2018 Nov;154(5):1044-1051. doi: 10.1016/j.chest.2018.04.025. Epub 2018 Apr 26.


We must look further upstream to enable planetary health-literate urban development.

Black D, Scally G, Hunt A, Orme J.

Lancet Planet Health. 2018 Apr;2(4):e145-e146. doi: 10.1016/S2542-5196(18)30045-7. Epub 2018 Apr 4. No abstract available.


Exploring the multidisciplinary extent of public health career structures in 12 countries: an exploratory mapping.

Manyara AM, Buunaaisie C, Annett H, Bird E, Bray I, Ige J, Jones M, Orme J, Pilkington P, Evans D.

J Public Health (Oxf). 2018 Dec 1;40(4):e538-e544. doi: 10.1093/pubmed/fdy057.


Antitumor Activity of Osimertinib, an Irreversible Mutant-Selective EGFR Tyrosine Kinase Inhibitor, in NSCLC Harboring EGFR Exon 20 Insertions.

Floc'h N, Martin MJ, Riess JW, Orme JP, Staniszewska AD, Ménard L, Cuomo ME, O'Neill DJ, Ward RA, Finlay MRV, McKerrecher D, Cheng M, Vang DP, Burich RA, Keck JG, Gandara DR, Mack PC, Cross DAE.

Mol Cancer Ther. 2018 May;17(5):885-896. doi: 10.1158/1535-7163.MCT-17-0758. Epub 2018 Feb 26.


Association of hospice utilization and publicly reported outcomes following hospitalization for pneumonia or heart failure: a retrospective cohort study.

Lah S, Wilson EL, Beesley S, Sagy I, Orme J, Novack V, Brown SM.

BMC Health Serv Res. 2018 Jan 9;18(1):12. doi: 10.1186/s12913-017-2801-3.


Acute Physiologic Stress and Subsequent Anxiety Among Family Members of ICU Patients.

Beesley SJ, Hopkins RO, Holt-Lunstad J, Wilson EL, Butler J, Kuttler KG, Orme J, Brown SM, Hirshberg EL.

Crit Care Med. 2018 Feb;46(2):229-235. doi: 10.1097/CCM.0000000000002835.


Food for Life: evaluation of the impact of the Hospital Food Programme in England using a case study approach.

Gray S, Orme J, Pitt H, Jones M.

JRSM Open. 2017 Oct 4;8(10):2054270417712703. doi: 10.1177/2054270417712703. eCollection 2017 Oct.


Axillary Mass and Hypercalcemia: The Value of a Physical Examination.

Orme J, Purushotham D.

Am J Med. 2017 Dec;130(12):e541-e542. doi: 10.1016/j.amjmed.2017.06.023. Epub 2017 Jul 17. No abstract available.


Association between Food for Life, a Whole Setting Healthy and Sustainable Food Programme, and Primary School Children's Consumption of Fruit and Vegetables: A Cross-Sectional Study in England.

Jones M, Pitt H, Oxford L, Bray I, Kimberlee R, Orme J.

Int J Environ Res Public Health. 2017 Jun 14;14(6). pii: E639. doi: 10.3390/ijerph14060639.


The Application of Salutogenesis in Universities.

Dooris M, Doherty S, Orme J.

In: Mittelmark MB, Sagy S, Eriksson M, Bauer GF, Pelikan JM, Lindström B, Espnes GA, editors. The Handbook of Salutogenesis [Internet]. Cham (CH): Springer; 2017. Chapter 23.
2016 Sep 3.


Examining the inter-correlated effects of low income, life stress, and race on birth outcomes: A representative state study.

Lefmann T, Combs-Orme T, Orme JG.

Soc Work Health Care. 2017 Jul;56(6):450-469. doi: 10.1080/00981389.2017.1316811. Epub 2017 May 9.


Patient and Family Experience: A Comparison of Intensive Care and Overall Hospitalization.

Lah S, Wilson EL, Rozenblum R, Hirshberg EL, Hopkins RO, Orme J, Brown SM.

Am J Crit Care. 2017 May;26(3):194-202. doi: 10.4037/ajcc2017143.


Inter-sectoral Transfer of the Food for Life Settings Framework in England.

Gray S, Jones M, Means R, Orme J, Pitt H, Salmon D.

Health Promot Int. 2018 Oct 1;33(5):781-790. doi: 10.1093/heapro/dax017.


Preliminary Identification of Coping Profiles Relevant to Surrogate Decision Making in the ICU.

Butler JM, Hirshberg EL, Hopkins RO, Wilson EL, Orme JF, Beesley SJ, Kuttler K, Brown SM.

PLoS One. 2016 Nov 11;11(11):e0166542. doi: 10.1371/journal.pone.0166542. eCollection 2016.


Leukocyte Beta-Catenin Expression Is Disturbed in Systemic Lupus Erythematosus.

Orme JJ, Du Y, Vanarsa K, Wu T, Satterthwaite AB, Mohan C.

PLoS One. 2016 Aug 22;11(8):e0161682. doi: 10.1371/journal.pone.0161682. eCollection 2016.


Heightened cleavage of Axl receptor tyrosine kinase by ADAM metalloproteases may contribute to disease pathogenesis in SLE.

Orme JJ, Du Y, Vanarsa K, Mayeux J, Li L, Mutwally A, Arriens C, Min S, Hutcheson J, Davis LS, Chong BF, Satterthwaite AB, Wu T, Mohan C.

Clin Immunol. 2016 Aug;169:58-68. doi: 10.1016/j.clim.2016.05.011. Epub 2016 May 27.


Utilization of Structure-Based Design to Identify Novel, Irreversible Inhibitors of EGFR Harboring the T790M Mutation.

Hennessy EJ, Chuaqui C, Ashton S, Colclough N, Cross DA, Debreczeni JÉ, Eberlein C, Gingipalli L, Klinowska TC, Orme JP, Sha L, Wu X.

ACS Med Chem Lett. 2016 Mar 21;7(5):514-9. doi: 10.1021/acsmedchemlett.6b00058. eCollection 2016 May 12.


Self-Rated Health Across Race, Ethnicity, and Immigration Status for US Adolescents and Young Adults.

Allen CD, McNeely CA, Orme JG.

J Adolesc Health. 2016 Jan;58(1):47-56. doi: 10.1016/j.jadohealth.2015.09.006. Epub 2015 Nov 7.


Sex Trafficking: Policies, Programs, and Services.

Orme J, Ross-Sheriff F.

Soc Work. 2015 Oct;60(4):287-94. Review.


Whole blood gene expression profiling of neonates with confirmed bacterial sepsis.

Dickinson P, Smith CL, Forster T, Craigon M, Ross AJ, Khondoker MR, Ivens A, Lynn DJ, Orme J, Jackson A, Lacaze P, Flanagan KL, Stenson BJ, Ghazal P.

Genom Data. 2014 Nov 15;3:41-8. doi: 10.1016/j.gdata.2014.11.003. eCollection 2015 Mar.


Examining Ligand-Based Stabilization of Proteins in Cells with MEK1 Kinase Inhibitors.

Auld DS, Davis CA, Jimenez M, Knight S, Orme JP.

Assay Drug Dev Technol. 2015 Jun;13(5):266-76. doi: 10.1089/adt.2014.614. Epub 2015 Jun 24.


Validation of the Intermountain patient perception of quality (PPQ) survey among survivors of an intensive care unit admission: a retrospective validation study.

Brown SM, McBride G, Collingridge DS, Butler JM, Kuttler KG, Hirshberg EL, Jones JP, Hopkins RO, Talmor D, Orme J; Center for Humanizing Critical Care.

BMC Health Serv Res. 2015 Apr 14;15:155. doi: 10.1186/s12913-015-0828-x.


Regional pericarditis status post cardiac ablation: a case report.

Orme J, Eddin M, Loli A.

N Am J Med Sci. 2015 Jan;7(1):33-5. No abstract available.


Native Valve Endocarditis due to Ralstonia pickettii: A Case Report and Literature Review.

Orme J, Rivera-Bonilla T, Loli A, Blattman NN.

Case Rep Infect Dis. 2015;2015:324675. doi: 10.1155/2015/324675. Epub 2015 Jan 11.


Regional pericarditis status post cardiac ablation: a case report.

Orme J, Eddin M, Loli A.

N Am J Med Sci. 2014 Sep;6(9):481-3. doi: 10.4103/1947-2714.141653.


Discovery of a potent and selective EGFR inhibitor (AZD9291) of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor.

Finlay MR, Anderton M, Ashton S, Ballard P, Bethel PA, Box MR, Bradbury RH, Brown SJ, Butterworth S, Campbell A, Chorley C, Colclough N, Cross DA, Currie GS, Grist M, Hassall L, Hill GB, James D, James M, Kemmitt P, Klinowska T, Lamont G, Lamont SG, Martin N, McFarland HL, Mellor MJ, Orme JP, Perkins D, Perkins P, Richmond G, Smith P, Ward RA, Waring MJ, Whittaker D, Wells S, Wrigley GL.

J Med Chem. 2014 Oct 23;57(20):8249-67. doi: 10.1021/jm500973a. Epub 2014 Oct 1.


Identification of a human neonatal immune-metabolic network associated with bacterial infection.

Smith CL, Dickinson P, Forster T, Craigon M, Ross A, Khondoker MR, France R, Ivens A, Lynn DJ, Orme J, Jackson A, Lacaze P, Flanagan KL, Stenson BJ, Ghazal P.

Nat Commun. 2014 Aug 14;5:4649. doi: 10.1038/ncomms5649.


Stridor in asphyxiated neonates undergoing therapeutic hypothermia.

Orme J, Kissack C, Becher JC.

Pediatrics. 2014 Jul;134(1):e261-5. doi: 10.1542/peds.2013-2053. Epub 2014 Jun 9.


AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer.

Cross DA, Ashton SE, Ghiorghiu S, Eberlein C, Nebhan CA, Spitzler PJ, Orme JP, Finlay MR, Ward RA, Mellor MJ, Hughes G, Rahi A, Jacobs VN, Red Brewer M, Ichihara E, Sun J, Jin H, Ballard P, Al-Kadhimi K, Rowlinson R, Klinowska T, Richmond GH, Cantarini M, Kim DW, Ranson MR, Pao W.

Cancer Discov. 2014 Sep;4(9):1046-61. doi: 10.1158/2159-8290.CD-14-0337. Epub 2014 Jun 3.


Coefficient of glucose variation is independently associated with mortality in critically ill patients receiving intravenous insulin.

Lanspa MJ, Dickerson J, Morris AH, Orme JF, Holmen J, Hirshberg EL.

Crit Care. 2014 Apr 30;18(2):R86. doi: 10.1186/cc13851.


Breastfeeding Knowledge, Attitudes, and Intention in a Sample of Undergraduate Students in Mainland China.

Lou Z, Zeng G, Orme JG, Huang L, Liu F, Pang X, Kavanagh KF.

J Hum Lact. 2014 Aug;30(3):331-339. Epub 2014 Mar 13.


The experiences of patients undergoing blood transfusion in a day hospice.

Orme J, Still D, Day R, Evans J, Perkins P.

Int J Palliat Nurs. 2013 Apr;19(4):171-6.


Structure- and reactivity-based development of covalent inhibitors of the activating and gatekeeper mutant forms of the epidermal growth factor receptor (EGFR).

Ward RA, Anderton MJ, Ashton S, Bethel PA, Box M, Butterworth S, Colclough N, Chorley CG, Chuaqui C, Cross DA, Dakin LA, Debreczeni JÉ, Eberlein C, Finlay MR, Hill GB, Grist M, Klinowska TC, Lane C, Martin S, Orme JP, Smith P, Wang F, Waring MJ.

J Med Chem. 2013 Sep 12;56(17):7025-48. doi: 10.1021/jm400822z. Epub 2013 Aug 30.


Biventricular takotsubo cardiomyopathy: case study and review of literature.

Daoko J, Rajachandran M, Savarese R, Orme J.

Tex Heart Inst J. 2013;40(3):305-11. Review.


A genopedia of lupus genes - lessons from gene knockouts.

Guo Y, Orme J, Mohan C.

Curr Rheumatol Rev. 2013;9(2):90-9.


Engaging a wider public health workforce for the future: a public health practitioner in residence approach.

Pilkington P, Marco E, Grant M, Orme J.

Public Health. 2013 May;127(5):427-34. doi: 10.1016/j.puhe.2012.12.026. Epub 2013 May 13.


Intra-articular nuclear factor-κB blockade ameliorates collagen-induced arthritis in mice by eliciting regulatory T cells and macrophages.

Min SY, Yan M, Du Y, Wu T, Khobahy E, Kwon SR, Taneja V, Bashmakov A, Nukala S, Ye Y, Orme J, Sajitharan D, Kim HY, Mohan C.

Clin Exp Immunol. 2013 May;172(2):217-27. doi: 10.1111/cei.12054.

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