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Items: 1 to 50 of 52

1.

The Genomic Medicine Integrative Research Framework: A Conceptual Framework for Conducting Genomic Medicine Research.

Horowitz CR, Orlando LA, Slavotinek AM, Peterson J, Angelo F, Biesecker B, Bonham VL, Cameron LD, Fullerton SM, Gelb BD, Goddard KAB, Hailu B, Hart R, Hindorff LA, Jarvik GP, Kaufman D, Kenny EE, Knight SJ, Koenig BA, Korf BR, Madden E, McGuire AL, Ou J, Wasserstein MP, Robinson M, Leventhal H, Sanderson SC.

Am J Hum Genet. 2019 Jun 6;104(6):1088-1096. doi: 10.1016/j.ajhg.2019.04.006. Epub 2019 May 16.

PMID:
31104772
2.

Use of clinical algorithms and rapid influenza testing to manage influenza-like illness: a cost-effectiveness analysis in Sri Lanka.

Tillekeratne LG, Bodinayake C, Nagahawatte A, Kurukulasooriya R, Orlando LA, Simmons RA, Park LP, Woods CW, Reed SD.

BMJ Glob Health. 2019 Mar 30;4(2):e001291. doi: 10.1136/bmjgh-2018-001291. eCollection 2019.

3.

IGNITE network: Response of patients to genomic medicine interventions.

Orlando LA, Voils C, Horowitz CR, Myers RA, Arwood MJ, Cicali EJ, McDonough CW, Pollin TI, Guan Y, Levy KD, Ramirez A, Quittner A, Madden EB.

Mol Genet Genomic Med. 2019 May;7(5):e636. doi: 10.1002/mgg3.636. Epub 2019 Mar 20.

4.

Effect of Sociodemographic Factors on Uptake of a Patient-Facing Information Technology Family Health History Risk Assessment Platform.

Wu RR, Myers RA, Buchanan AH, Dimmock D, Fulda KG, Haller IV, Haga SB, Harry ML, McCarty C, Neuner J, Rakhra-Burris T, Sperber N, Voils CI, Ginsburg GS, Orlando LA.

Appl Clin Inform. 2019 Mar;10(2):180-188. doi: 10.1055/s-0039-1679926. Epub 2019 Mar 13.

PMID:
30866001
5.

Efficacy of a Preference-Based Decision Tool on Treatment Decisions for a First-Time Anterior Shoulder Dislocation: A Randomized Controlled Trial of At-Risk Patients.

Hutyra CA, Smiley S, Taylor DC, Orlando LA, Mather RC 3rd.

Med Decis Making. 2019 Apr;39(3):253-263. doi: 10.1177/0272989X19832915. Epub 2019 Mar 5.

PMID:
30834817
6.

Assessing the Effectiveness of Evidence-Based Medicine in Practice: A Case Study of First-Time Anterior Shoulder Dislocations.

Hutyra CA, Streufert B, Politzer CS, Agaba P, Rubin E, Orlando LA, Taylor DC, Mather RC 3rd.

J Bone Joint Surg Am. 2019 Jan 16;101(2):e6. doi: 10.2106/JBJS.17.01588.

PMID:
30653051
7.

Qualitative study of system-level factors related to genomic implementation.

Zebrowski AM, Ellis DE, Barg FK, Sperber NR, Bernhardt BA, Denny JC, Dexter PR, Ginsburg GS, Horowitz CR, Johnson JA, Levy MA, Orlando LA, Pollin TI, Skaar TC, Kimmel SE.

Genet Med. 2019 Jul;21(7):1534-1540. doi: 10.1038/s41436-018-0378-9. Epub 2018 Nov 23.

8.

Implementation, adoption, and utility of family health history risk assessment in diverse care settings: evaluating implementation processes and impact with an implementation framework.

Wu RR, Myers RA, Sperber N, Voils CI, Neuner J, McCarty CA, Haller IV, Harry M, Fulda KG, Cross D, Dimmock D, Rakhra-Burris T, Buchanan AH, Ginsburg GS, Orlando LA.

Genet Med. 2019 Feb;21(2):331-338. doi: 10.1038/s41436-018-0049-x. Epub 2018 Jun 6.

9.

Developing a common framework for evaluating the implementation of genomic medicine interventions in clinical care: the IGNITE Network's Common Measures Working Group.

Orlando LA, Sperber NR, Voils C, Nichols M, Myers RA, Wu RR, Rakhra-Burris T, Levy KD, Levy M, Pollin TI, Guan Y, Horowitz CR, Ramos M, Kimmel SE, McDonough CW, Madden EB, Damschroder LJ.

Genet Med. 2018 Jun;20(6):655-663. doi: 10.1038/gim.2017.144. Epub 2017 Sep 14.

10.

Challenges and strategies for implementing genomic services in diverse settings: experiences from the Implementing GeNomics In pracTicE (IGNITE) network.

Sperber NR, Carpenter JS, Cavallari LH, J Damschroder L, Cooper-DeHoff RM, Denny JC, Ginsburg GS, Guan Y, Horowitz CR, Levy KD, Levy MA, Madden EB, Matheny ME, Pollin TI, Pratt VM, Rosenman M, Voils CI, W Weitzel K, Wilke RA, Ryanne Wu R, Orlando LA.

BMC Med Genomics. 2017 May 22;10(1):35. doi: 10.1186/s12920-017-0273-2.

11.

Making genomic medicine evidence-based and patient-centered: a structured review and landscape analysis of comparative effectiveness research.

Phillips KA, Deverka PA, Sox HC, Khoury MJ, Sandy LG, Ginsburg GS, Tunis SR, Orlando LA, Douglas MP.

Genet Med. 2017 Oct;19(10):1081-1091. doi: 10.1038/gim.2017.21. Epub 2017 Apr 13. Review.

12.

Understanding Preferences for Treatment After Hypothetical First-Time Anterior Shoulder Dislocation: Surveying an Online Panel Utilizing a Novel Shared Decision-Making Tool.

Streufert B, Reed SD, Orlando LA, Taylor DC, Huber JC, Mather RC 3rd.

Orthop J Sports Med. 2017 Mar 20;5(3):2325967117695788. doi: 10.1177/2325967117695788. eCollection 2017 Mar.

13.

Family health history: an essential starting point for personalized risk assessment and disease prevention.

Henrich VC, Orlando LA.

Per Med. 2016 Sep;13(5):499-510. doi: 10.2217/pme-2016-0007. Epub 2016 Aug 3.

PMID:
29767594
14.

Impact of Genetic Testing and Family Health History Based Risk Counseling on Behavior Change and Cognitive Precursors for Type 2 Diabetes.

Wu RR, Myers RA, Hauser ER, Vorderstrasse A, Cho A, Ginsburg GS, Orlando LA.

J Genet Couns. 2017 Feb;26(1):133-140. doi: 10.1007/s10897-016-9988-z. Epub 2016 Jun 14.

PMID:
27296809
15.

Clinical utility of a Web-enabled risk-assessment and clinical decision support program.

Orlando LA, Wu RR, Myers RA, Buchanan AH, Henrich VC, Hauser ER, Ginsburg GS.

Genet Med. 2016 Oct;18(10):1020-8. doi: 10.1038/gim.2015.210. Epub 2016 Mar 3.

PMID:
26938783
16.

The IGNITE network: a model for genomic medicine implementation and research.

Weitzel KW, Alexander M, Bernhardt BA, Calman N, Carey DJ, Cavallari LH, Field JR, Hauser D, Junkins HA, Levin PA, Levy K, Madden EB, Manolio TA, Odgis J, Orlando LA, Pyeritz R, Wu RR, Shuldiner AR, Bottinger EP, Denny JC, Dexter PR, Flockhart DA, Horowitz CR, Johnson JA, Kimmel SE, Levy MA, Pollin TI, Ginsburg GS; IGNITE Network.

BMC Med Genomics. 2016 Jan 5;9:1. doi: 10.1186/s12920-015-0162-5.

17.

Protocol for the "Implementation, adoption, and utility of family history in diverse care settings" study.

Wu RR, Myers RA, McCarty CA, Dimmock D, Farrell M, Cross D, Chinevere TD, Ginsburg GS, Orlando LA; Family Health History Network.

Implement Sci. 2015 Nov 24;10:163. doi: 10.1186/s13012-015-0352-8.

18.

Implementation of health risk assessments with family health history: barriers and benefits.

Wu RR, Orlando LA.

Postgrad Med J. 2015 Sep;91(1079):508-13. doi: 10.1136/postgradmedj-2014-133195. Epub 2015 Aug 12. Review.

PMID:
26268266
19.

Compendia for Coverage of Off-label Uses of Drugs and Biologics in an Anticancer Chemotherapeutic Regimen [Internet].

Abernethy AP, Hammond JM, Hubbard ML, Patwardhan MB, Orlando LA, McCrory DC, Balk E, Raman G, Chew P, Kupelnick B, Lau J.

Rockville (MD): Agency for Healthcare Research and Quality (US); 2007 May 7.

20.

Patient beliefs and behaviors about genomic risk for type 2 diabetes: implications for prevention.

Gallagher P, King HA, Haga SB, Orlando LA, Joy SV, Trujillo GM, Scott WM, Bembe M, Creighton DL, Cho AH, Ginsburg GS, Vorderstrasse A.

J Health Commun. 2015;20(6):728-35. doi: 10.1080/10810730.2015.1018563. Epub 2015 Apr 6.

PMID:
25844569
21.

Genetically guided statin therapy on statin perceptions, adherence, and cholesterol lowering: a pilot implementation study in primary care patients.

Li JH, Joy SV, Haga SB, Orlando LA, Kraus WE, Ginsburg GS, Voora D.

J Pers Med. 2014 Mar 27;4(2):147-62. doi: 10.3390/jpm4020147.

22.

Non-Invasive Imaging for Coronary Artery Disease [Internet].

Matchar DB, Mark DB, Patel MR, Hurwitz LM, Orlando LA, McCrory DC, Sanders GD.

Rockville (MD): Agency for Healthcare Research and Quality (US); 2006 Oct 3.

23.

Cost-effectiveness analysis of the diagnosis of meniscus tears.

Mather RC 3rd, Garrett WE, Cole BJ, Hussey K, Bolognesi MP, Lassiter T, Orlando LA.

Am J Sports Med. 2015 Jan;43(1):128-37. doi: 10.1177/0363546514557937. Epub 2014 Dec 1.

PMID:
25451791
24.

Use of a patient-entered family health history tool with decision support in primary care: impact of identification of increased risk patients on genetic counseling attendance.

Buchanan AH, Christianson CA, Himmel T, Powell KP, Agbaje A, Ginsburg GS, Henrich VC, Orlando LA.

J Genet Couns. 2015 Feb;24(1):179-88. doi: 10.1007/s10897-014-9753-0. Epub 2014 Aug 15.

PMID:
25120038
25.

The future of genomic testing in primary care: the changing face of personalized medicine.

Bartlett G, Rahimzadeh V, Longo C, Orlando LA, Dawes M, Lachaine J, Bochud M, Paccaud F, Bergman H, Crimi L, Issa AM.

Per Med. 2014 Jul;11(5):477-486. doi: 10.2217/pme.14.36.

PMID:
29758776
26.

Implementing family health history risk stratification in primary care: impact of guideline criteria on populations and resource demand.

Orlando LA, Wu RR, Beadles C, Himmel T, Buchanan AH, Powell KP, Hauser ER, Henrich VC, Ginsburg GS.

Am J Med Genet C Semin Med Genet. 2014 Mar;166C(1):24-33. doi: 10.1002/ajmg.c.31388. Epub 2014 Mar 10.

PMID:
24616329
27.

Quality of family history collection with use of a patient facing family history assessment tool.

Wu RR, Himmel TL, Buchanan AH, Powell KP, Hauser ER, Ginsburg GS, Henrich VC, Orlando LA.

BMC Fam Pract. 2014 Feb 13;15:31. doi: 10.1186/1471-2296-15-31.

28.

Providing patient education: impact on quantity and quality of family health history collection.

Beadles CA, Ryanne Wu R, Himmel T, Buchanan AH, Powell KP, Hauser E, Henrich VC, Ginsburg GS, Orlando LA.

Fam Cancer. 2014 Jun;13(2):325-32. doi: 10.1007/s10689-014-9701-z.

PMID:
24515581
29.

Economic evaluation of access to musculoskeletal care: the case of waiting for total knee arthroplasty.

Mather RC 3rd, Hug KT, Orlando LA, Watters TS, Koenig L, Nunley RM, Bolognesi MP.

BMC Musculoskelet Disord. 2014 Jan 18;15:22. doi: 10.1186/1471-2474-15-22.

30.

Bacterial natural transformation by highly fragmented and damaged DNA.

Overballe-Petersen S, Harms K, Orlando LA, Mayar JV, Rasmussen S, Dahl TW, Rosing MT, Poole AM, Sicheritz-Ponten T, Brunak S, Inselmann S, de Vries J, Wackernagel W, Pybus OG, Nielsen R, Johnsen PJ, Nielsen KM, Willerslev E.

Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19860-5. doi: 10.1073/pnas.1315278110. Epub 2013 Nov 18.

31.

Development and validation of a primary care-based family health history and decision support program (MeTree).

Orlando LA, Buchanan AH, Hahn SE, Christianson CA, Powell KP, Skinner CS, Chesnut B, Blach C, Due B, Ginsburg GS, Henrich VC.

N C Med J. 2013 Jul-Aug;74(4):287-96.

32.

Collection of family health history for assessment of chronic disease risk in primary care.

Powell KP, Christianson CA, Hahn SE, Dave G, Evans LR, Blanton SH, Hauser E, Agbaje A, Orlando LA, Ginsburg GS, Henrich VC.

N C Med J. 2013 Jul-Aug;74(4):279-86.

PMID:
24044144
33.

Patient and primary care provider experience using a family health history collection, risk stratification, and clinical decision support tool: a type 2 hybrid controlled implementation-effectiveness trial.

Wu RR, Orlando LA, Himmel TL, Buchanan AH, Powell KP, Hauser ER, Agbaje AB, Henrich VC, Ginsburg GS.

BMC Fam Pract. 2013 Aug 6;14:111. doi: 10.1186/1471-2296-14-111.

34.

Clinical utility of genetic risk testing in primary care: the example of Type 2 diabetes.

Vorderstrasse AA, Cho A, Voils CI, Orlando LA, Ginsburg GS.

Per Med. 2013 Aug;10(6):549-563. doi: 10.2217/pme.13.47.

PMID:
29776196
35.

The genomic medicine model: an integrated approach to implementation of family health history in primary care.

Orlando LA, Henrich VC, Hauser ER, Wilson C, Ginsburg GS; Genomedical Connection.

Per Med. 2013 May;10(3):295-306. doi: 10.2217/pme.13.20.

PMID:
29768748
36.

Cost-effectiveness analysis of free vascularized fibular grafting for osteonecrosis of the femoral head.

Watters TS, Browne JA, Orlando LA, Wellman SS, Urbaniak JR, Bolognesi MP.

J Surg Orthop Adv. 2011 Fall;20(3):158-67.

PMID:
22214140
37.

Protocol for implementation of family health history collection and decision support into primary care using a computerized family health history system.

Orlando LA, Hauser ER, Christianson C, Powell KP, Buchanan AH, Chesnut B, Agbaje AB, Henrich VC, Ginsburg G.

BMC Health Serv Res. 2011 Oct 11;11:264. doi: 10.1186/1472-6963-11-264.

38.

The chronic kidney disease model: a general purpose model of disease progression and treatment.

Orlando LA, Belasco EJ, Patel UD, Matchar DB.

BMC Med Inform Decis Mak. 2011 Jun 16;11:41. doi: 10.1186/1472-6947-11-41.

39.

Comparative Effectiveness of Angiotensin-Converting Enzyme Inhibitors (ACEIs) and Angiotensin II Receptor Antagonists (ARBs) for Treating Essential Hypertension [Internet].

Matchar DB, McCrory DC, Orlando LA, Patel MR, Patel UD, Patwardhan MB, Powers B, Samsa GP, Gray RN.

Rockville (MD): Agency for Healthcare Research and Quality (US); 2007 Nov.

40.

Genomic risk profiling: attitudes and use in personal and clinical care of primary care physicians who offer risk profiling.

Haga SB, Carrig MM, O'Daniel JM, Orlando LA, Killeya-Jones LA, Ginsburg GS, Cho A.

J Gen Intern Med. 2011 Aug;26(8):834-40. doi: 10.1007/s11606-011-1651-7. Epub 2011 Feb 11.

41.

A predictive model of shoulder instability after a first-time anterior shoulder dislocation.

Mather RC 3rd, Orlando LA, Henderson RA, Lawrence JT, Taylor DC.

J Shoulder Elbow Surg. 2011 Mar;20(2):259-66. doi: 10.1016/j.jse.2010.10.037.

PMID:
21276928
42.

Cost effectiveness analysis of hemiarthroplasty and total shoulder arthroplasty.

Mather RC 3rd, Watters TS, Orlando LA, Bolognesi MP, Moorman CT 3rd.

J Shoulder Elbow Surg. 2010 Apr;19(3):325-34. doi: 10.1016/j.jse.2009.11.057.

PMID:
20303459
43.

Dilated intercellular spaces as a marker of GERD.

Orlando LA, Orlando RC.

Curr Gastroenterol Rep. 2009 Jun;11(3):190-4. Review.

PMID:
19463218
44.

Systematic review: reliability of compendia methods for off-label oncology indications.

Abernethy AP, Raman G, Balk EM, Hammond JM, Orlando LA, Wheeler JL, Lau J, McCrory DC.

Ann Intern Med. 2009 Mar 3;150(5):336-43. Epub 2009 Feb 16. Review. Erratum in: Ann Intern Med. 2009 Apr 21;150(8):571.

PMID:
19221366
45.

Evaluation of the PharmGKB knowledge base as a resource for efficiently assessing the clinical validity and utility of pharmacogenetic assays.

Kawamoto K, Orlando LA, Voora D, Lobach DF, Joy S, Cho A, Ginsburg GS.

AMIA Annu Symp Proc. 2009 Nov 14;2009:307-11.

46.

Review of evidence for genetic testing for CYP450 polymorphisms in management of patients with nonpsychotic depression with selective serotonin reuptake inhibitors.

Thakur M, Grossman I, McCrory DC, Orlando LA, Steffens DC, Cline KE, Gray RN, Farmer J, DeJesus G, O'Brien C, Samsa G, Goldstein DB, Matchar DB.

Genet Med. 2007 Dec;9(12):826-35. Review.

PMID:
18091432
47.

Systematic review: comparative effectiveness of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers for treating essential hypertension.

Matchar DB, McCrory DC, Orlando LA, Patel MR, Patel UD, Patwardhan MB, Powers B, Samsa GP, Gray RN.

Ann Intern Med. 2008 Jan 1;148(1):16-29. Epub 2007 Nov 5. Review.

PMID:
17984484
48.

Testing for cytochrome P450 polymorphisms in adults with non-psychotic depression treated with selective serotonin reuptake inhibitors (SSRIs).

Matchar DB, Thakur ME, Grossman I, McCrory DC, Orlando LA, Steffens DC, Goldstein DB, Cline KE, Gray RN.

Evid Rep Technol Assess (Full Rep). 2007 Jan;(146):1-77. Review.

49.

Relationship between nephrologist care and progression of chronic kidney disease.

Orlando LA, Owen WF, Matchar DB.

N C Med J. 2007 Jan-Feb;68(1):9-16.

PMID:
17500426
50.

Chronic hypergastrinemia: causes and consequences.

Orlando LA, Lenard L, Orlando RC.

Dig Dis Sci. 2007 Oct;52(10):2482-9. Epub 2007 Apr 6. Review.

PMID:
17415644

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