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Items: 1 to 50 of 190

1.

Novel tacrine-benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer's Disease.

Fancellu G, Chand K, Tomás D, Orlandini E, Piemontese L, Silva DF, Cardoso SM, Chaves S, Santos MA.

J Enzyme Inhib Med Chem. 2020 Dec;35(1):211-226. doi: 10.1080/14756366.2019.1689237.

PMID:
31760822
2.

Synthesis and investigation of polyhydroxylated pyrrolidine derivatives as novel chemotypes showing dual activity as glucosidase and aldose reductase inhibitors.

Guazzelli L, D'Andrea F, Sartini S, Giorgelli F, Confini G, Quattrini L, Piano I, Nencetti S, Orlandini E, Gargini C, La Motta C.

Bioorg Chem. 2019 Nov;92:103298. doi: 10.1016/j.bioorg.2019.103298. Epub 2019 Sep 19.

PMID:
31557624
3.

Plectoneme dynamics and statistics in braided polymers.

Forte G, Caraglio M, Marenduzzo D, Orlandini E.

Phys Rev E. 2019 May;99(5-1):052503. doi: 10.1103/PhysRevE.99.052503.

PMID:
31212427
4.

Sequence and structural patterns detected in entangled proteins reveal the importance of co-translational folding.

Baiesi M, Orlandini E, Seno F, Trovato A.

Sci Rep. 2019 Jun 10;9(1):8426. doi: 10.1038/s41598-019-44928-3.

5.

Synergy of topoisomerase and structural-maintenance-of-chromosomes proteins creates a universal pathway to simplify genome topology.

Orlandini E, Marenduzzo D, Michieletto D.

Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8149-8154. doi: 10.1073/pnas.1815394116. Epub 2019 Apr 8.

6.

Increasing imported malaria in children and adults in Tuscany, Italy, (2000 to 2017): A retrospective analysis.

Panin F, Orlandini E, Galli L, De Martino M, Chiappini E.

Travel Med Infect Dis. 2019 May - Jun;29:34-39. doi: 10.1016/j.tmaid.2019.03.011. Epub 2019 Apr 2.

PMID:
30951904
7.

Lamellar ordering, droplet formation and phase inversion in exotic active emulsions.

Bonelli F, Carenza LN, Gonnella G, Marenduzzo D, Orlandini E, Tiribocchi A.

Sci Rep. 2019 Feb 26;9(1):2801. doi: 10.1038/s41598-019-39190-6.

8.

Physical principles of retroviral integration in the human genome.

Michieletto D, Lusic M, Marenduzzo D, Orlandini E.

Nat Commun. 2019 Feb 4;10(1):575. doi: 10.1038/s41467-019-08333-8.

9.

Age-related Macular Degeneration: Current Knowledge of Zinc Metalloproteinases Involvement.

Liva F, Cuffaro D, Nuti E, Nencetti S, Orlandini E, Vozzi G, Rossello A.

Curr Drug Targets. 2019;20(9):903-918. doi: 10.2174/1389450120666190122114857.

PMID:
30666909
10.

Design, synthesis and biological evaluation of bifunctional inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP).

Cuffaro D, Nuti E, Gifford V, Ito N, Camodeca C, Tuccinardi T, Nencetti S, Orlandini E, Itoh Y, Rossello A.

Bioorg Med Chem. 2019 Jan 1;27(1):196-207. doi: 10.1016/j.bmc.2018.11.041. Epub 2018 Nov 29.

PMID:
30522899
11.

Matrix metalloproteinase-12 inhibitors: synthesis, structure-activity relationships and intestinal absorption of novel sugar-based biphenylsulfonamide carboxylates.

Cuffaro D, Camodeca C, D'Andrea F, Piragine E, Testai L, Calderone V, Orlandini E, Nuti E, Rossello A.

Bioorg Med Chem. 2018 Dec 1;26(22):5804-5815. doi: 10.1016/j.bmc.2018.10.024. Epub 2018 Oct 26.

PMID:
30429099
12.

Copper mediated amyloid-β binding to Transthyretin.

Ciccone L, Fruchart-Gaillard C, Mourier G, Savko M, Nencetti S, Orlandini E, Servent D, Stura EA, Shepard W.

Sci Rep. 2018 Sep 13;8(1):13744. doi: 10.1038/s41598-018-31808-5.

13.

Hospitalization rates and outcome of invasive bacterial vaccine-preventable diseases in Tuscany: a historical cohort study of the 2000-2016 period.

Chiappini E, Inturrisi F, Orlandini E, de Martino M, de Waure C.

BMC Infect Dis. 2018 Aug 13;18(1):396. doi: 10.1186/s12879-018-3316-1.

14.

Discovering privileged topologies of molecular knots with self-assembling models.

Marenda M, Orlandini E, Micheletti C.

Nat Commun. 2018 Aug 3;9(1):3051. doi: 10.1038/s41467-018-05413-z.

15.

KymoKnot: A web server and software package to identify and locate knots in trajectories of linear or circular polymers.

Tubiana L, Polles G, Orlandini E, Micheletti C.

Eur Phys J E Soft Matter. 2018 Jun 7;41(6):72. doi: 10.1140/epje/i2018-11681-0.

PMID:
29884956
16.

Development of Thioaryl-Based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR, and Crystallographic Studies.

Nuti E, Cuffaro D, Bernardini E, Camodeca C, Panelli L, Chaves S, Ciccone L, Tepshi L, Vera L, Orlandini E, Nencetti S, Stura EA, Santos MA, Dive V, Rossello A.

J Med Chem. 2018 May 24;61(10):4421-4435. doi: 10.1021/acs.jmedchem.8b00096. Epub 2018 May 16.

PMID:
29727184
17.

Wall accumulation of bacteria with different motility patterns.

Sartori P, Chiarello E, Jayaswal G, Pierno M, Mistura G, Brun P, Tiribocchi A, Orlandini E.

Phys Rev E. 2018 Feb;97(2-1):022610. doi: 10.1103/PhysRevE.97.022610.

PMID:
29548231
18.

The value of endocervical curettage during loop electrosurgical excision procedures in predicting persistent/recurrent preinvasive cervical disease.

Cuello MA, Espinosa ME, Orlandini EJ, Hwang DY.

Int J Gynaecol Obstet. 2018 Jun;141(3):337-343. doi: 10.1002/ijgo.12480. Epub 2018 Mar 22.

PMID:
29509961
19.

Shaping epigenetic memory via genomic bookmarking.

Michieletto D, Chiang M, Colì D, Papantonis A, Orlandini E, Cook PR, Marenduzzo D.

Nucleic Acids Res. 2018 Jan 9;46(1):83-93. doi: 10.1093/nar/gkx1200.

20.

Epigenetic Transitions and Knotted Solitons in Stretched Chromatin.

Michieletto D, Orlandini E, Marenduzzo D.

Sci Rep. 2017 Nov 7;7(1):14642. doi: 10.1038/s41598-017-13916-w.

21.

Switching dynamics in cholesteric liquid crystal emulsions.

Fadda F, Gonnella G, Marenduzzo D, Orlandini E, Tiribocchi A.

J Chem Phys. 2017 Aug 14;147(6):064903. doi: 10.1063/1.4997637.

PMID:
28810771
22.

Ring Polymers: Threadings, Knot Electrophoresis and Topological Glasses.

Michieletto D, Marenduzzo D, Orlandini E, Turner MS.

Polymers (Basel). 2017 Aug 8;9(8). pii: E349. doi: 10.3390/polym9080349. Review.

23.

Entropic elasticity and dynamics of the bacterial chromosome: A simulation study.

Pereira MCF, Brackley CA, Lintuvuori JS, Marenduzzo D, Orlandini E.

J Chem Phys. 2017 Jul 28;147(4):044908. doi: 10.1063/1.4995992.

PMID:
28764377
24.

Mechanical Pulling of Linked Ring Polymers: Elastic Response and Link Localisation.

Caraglio M, Micheletti C, Orlandini E.

Polymers (Basel). 2017 Aug 1;9(8). pii: E327. doi: 10.3390/polym9080327.

25.

Synthesis and antiangiogenic activity study of new hop chalcone Xanthohumol analogues.

Nuti E, Bassani B, Camodeca C, Rosalia L, Cantelmo A, Gallo C, Baci D, Bruno A, Orlandini E, Nencetti S, Noonan DM, Albini A, Rossello A.

Eur J Med Chem. 2017 Sep 29;138:890-899. doi: 10.1016/j.ejmech.2017.07.024. Epub 2017 Jul 17.

PMID:
28750311
26.

Non-monotonic knotting probability and knot length of semiflexible rings: the competing roles of entropy and bending energy.

Coronel L, Orlandini E, Micheletti C.

Soft Matter. 2017 Jun 14;13(23):4260-4267. doi: 10.1039/c7sm00643h.

PMID:
28573303
27.

Physical Links: defining and detecting inter-chain entanglement.

Caraglio M, Micheletti C, Orlandini E.

Sci Rep. 2017 Apr 25;7(1):1156. doi: 10.1038/s41598-017-01200-w.

28.

N-(Aroyl)-N-(arylmethyloxy)-α-alanines: Selective inhibitors of aldose reductase.

Nencetti S, La Motta C, Rossello A, Sartini S, Nuti E, Ciccone L, Orlandini E.

Bioorg Med Chem. 2017 Jun 15;25(12):3068-3076. doi: 10.1016/j.bmc.2017.03.056. Epub 2017 Mar 28.

PMID:
28392277
29.

Bifunctional Inhibitors as a New Tool To Reduce Cancer Cell Invasion by Impairing MMP-9 Homodimerization.

Nuti E, Rosalia L, Cuffaro D, Camodeca C, Giacomelli C, Da Pozzo E, Tuccinardi T, Costa B, Antoni C, Vera L, Ciccone L, Orlandini E, Nencetti S, Dive V, Martini C, Stura EA, Rossello A.

ACS Med Chem Lett. 2017 Feb 7;8(3):293-298. doi: 10.1021/acsmedchemlett.6b00446. eCollection 2017 Mar 9.

30.

Spatial confinement induces hairpins in nicked circular DNA.

Japaridze A, Orlandini E, Smith KB, Gmür L, Valle F, Micheletti C, Dietler G.

Nucleic Acids Res. 2017 May 5;45(8):4905-4914. doi: 10.1093/nar/gkx098.

31.

Sorting ring polymers by knot type with modulated nanochannels.

Marenda M, Orlandini E, Micheletti C.

Soft Matter. 2017 Jan 25;13(4):795-802. doi: 10.1039/c6sm02551j.

PMID:
28058437
32.

Comparison of helical scan and standard rotation methods in single-crystal X-ray data collection strategies.

Polsinelli I, Savko M, Rouanet-Mehouas C, Ciccone L, Nencetti S, Orlandini E, Stura EA, Shepard W.

J Synchrotron Radiat. 2017 Jan 1;24(Pt 1):42-52. doi: 10.1107/S1600577516018488. Epub 2017 Jan 1.

PMID:
28009545
33.

Shear dynamics of an inverted nematic emulsion.

Tiribocchi A, Da Re M, Marenduzzo D, Orlandini E.

Soft Matter. 2016 Oct 4;12(39):8195-8213.

PMID:
27714315
34.

Linking in domain-swapped protein dimers.

Baiesi M, Orlandini E, Trovato A, Seno F.

Sci Rep. 2016 Sep 23;6:33872. doi: 10.1038/srep33872.

35.

Single-File Escape of Colloidal Particles from Microfluidic Channels.

Locatelli E, Pierno M, Baldovin F, Orlandini E, Tan Y, Pagliara S.

Phys Rev Lett. 2016 Jul 15;117(3):038001. doi: 10.1103/PhysRevLett.117.038001. Epub 2016 Jul 12.

PMID:
27472142
36.

Dramatic Pertussis Resurgence in Tuscan Infants in 2014.

Chiappini E, Berti E, Sollai S, Orlandini E, Galli L, de Martino M.

Pediatr Infect Dis J. 2016 Aug;35(8):930-1. doi: 10.1097/INF.0000000000001198. No abstract available.

PMID:
27416012
37.

Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors.

Nuti E, Cuffaro D, D'Andrea F, Rosalia L, Tepshi L, Fabbi M, Carbotti G, Ferrini S, Santamaria S, Camodeca C, Ciccone L, Orlandini E, Nencetti S, Stura EA, Dive V, Rossello A.

ChemMedChem. 2016 Aug 5;11(15):1626-37. doi: 10.1002/cmdc.201600235. Epub 2016 Jun 30.

PMID:
27356908
38.

Analysis of measles-related hospitalizations in Tuscany from 2000 to 2014.

Berti E, Sollai S, Orlandini E, Galli L, DE Martino M, Chiappini E.

Epidemiol Infect. 2016 Sep;144(12):2605-12. doi: 10.1017/S0950268816001023. Epub 2016 May 31.

PMID:
27240964
39.

Targeting Different Transthyretin Binding Sites with Unusual Natural Compounds.

Ortore G, Orlandini E, Braca A, Ciccone L, Rossello A, Martinelli A, Nencetti S.

ChemMedChem. 2016 Aug 19;11(16):1865-74. doi: 10.1002/cmdc.201600092. Epub 2016 May 9.

PMID:
27159149
40.

Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR).

Ciccone L, Nencetti S, Rossello A, Stura EA, Orlandini E.

J Enzyme Inhib Med Chem. 2016;31(sup1):40-51. Epub 2016 Apr 11.

PMID:
27067161
41.

Correction: Curvature-driven positioning of Turing patterns in phase-separating curved membranes.

Vandin G, Marenduzzo D, Goryachev AB, Orlandini E.

Soft Matter. 2016 Apr 20;12(16):3828. doi: 10.1039/c6sm90059c.

PMID:
27052157
42.

Curvature-driven positioning of Turing patterns in phase-separating curved membranes.

Vandin G, Marenduzzo D, Goryachev AB, Orlandini E.

Soft Matter. 2016 May 7;12(17):3888-96. doi: 10.1039/c6sm00340k. Epub 2016 Mar 24. Erratum in: Soft Matter. 2016 Apr 20;12(16):3828.

PMID:
27010222
43.

A new crystal form of human transthyretin obtained with a curcumin derived ligand.

Polsinelli I, Nencetti S, Shepard W, Ciccone L, Orlandini E, Stura EA.

J Struct Biol. 2016 Apr;194(1):8-17. doi: 10.1016/j.jsb.2016.01.007. Epub 2016 Jan 18.

PMID:
26796656
44.

Stretching Response of Knotted and Unknotted Polymer Chains.

Caraglio M, Micheletti C, Orlandini E.

Phys Rev Lett. 2015 Oct 30;115(18):188301. doi: 10.1103/PhysRevLett.115.188301. Epub 2015 Oct 27.

PMID:
26565504
45.

Topological patterns in two-dimensional gel electrophoresis of DNA knots.

Michieletto D, Marenduzzo D, Orlandini E.

Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):E5471-7. doi: 10.1073/pnas.1506907112. Epub 2015 Sep 8.

46.

Knotting dynamics of DNA chains of different length confined in nanochannels.

Suma A, Orlandini E, Micheletti C.

J Phys Condens Matter. 2015 Sep 9;27(35):354102. doi: 10.1088/0953-8984/27/35/354102. Epub 2015 Aug 20.

PMID:
26291786
47.

N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity.

Nuti E, Cantelmo AR, Gallo C, Bruno A, Bassani B, Camodeca C, Tuccinardi T, Vera L, Orlandini E, Nencetti S, Stura EA, Martinelli A, Dive V, Albini A, Rossello A.

J Med Chem. 2015 Sep 24;58(18):7224-40. doi: 10.1021/acs.jmedchem.5b00367. Epub 2015 Aug 28.

PMID:
26263024
48.

X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors.

Ciccone L, Nencetti S, Rossello A, Tepshi L, Stura EA, Orlandini E.

J Enzyme Inhib Med Chem. 2016 Oct;31(5):824-33. doi: 10.3109/14756366.2015.1070265. Epub 2015 Aug 3.

PMID:
26235916
49.

Electric field controlled columnar and planar patterning of cholesteric colloids.

D'Adamo G, Marenduzzo D, Micheletti C, Orlandini E.

Phys Rev Lett. 2015 May 1;114(17):177801. Epub 2015 Apr 30.

PMID:
25978263
50.

Is the kinetoplast DNA a percolating network of linked rings at its critical point?

Michieletto D, Marenduzzo D, Orlandini E.

Phys Biol. 2015 May 13;12(3):036001. doi: 10.1088/1478-3975/12/3/036001.

PMID:
25970016

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