Sort by
Items per page

Send to

Choose Destination

Search results

Items: 41


Modulation of Mast Cell Reactivity by Lipids: The Neglected Side of Allergic Diseases.

Hagemann PM, Nsiah-Dosu S, Hundt JE, Hartmann K, Orinska Z.

Front Immunol. 2019 May 29;10:1174. doi: 10.3389/fimmu.2019.01174. eCollection 2019. Review.


Lipid Mediators From Timothy Grass Pollen Contribute to the Effector Phase of Allergy and Prime Dendritic Cells for Glycolipid Presentation.

González Roldán N, Engel R, Düpow S, Jakob K, Koops F, Orinska Z, Vigor C, Oger C, Galano JM, Durand T, Jappe U, Duda KA.

Front Immunol. 2019 May 7;10:974. doi: 10.3389/fimmu.2019.00974. eCollection 2019.


Mast cells as protectors of health.

Dudeck A, Köberle M, Goldmann O, Meyer N, Dudeck J, Lemmens S, Rohde M, Roldán NG, Dietze-Schwonberg K, Orinska Z, Medina E, Hendrix S, Metz M, Zenclussen AC, von Stebut E, Biedermann T.

J Allergy Clin Immunol. 2019 Oct;144(4S):S4-S18. doi: 10.1016/j.jaci.2018.10.054. Epub 2018 Nov 20.


C5a receptor 1-/- mice are protected from the development of IgE-mediated experimental food allergy.

Kordowski A, Reinicke AT, Wu D, Orinska Z, Hagemann P, Huber-Lang M, Lee JB, Wang YH, Hogan SP, Köhl J.

Allergy. 2019 Apr;74(4):767-779. doi: 10.1111/all.13637. Epub 2018 Nov 12.


Interleukin-9 promotes early mast cell-mediated expulsion of Strongyloides ratti but is dispensable for generation of protective memory.

Reitz M, Hartmann W, Rüdiger N, Orinska Z, Brunn ML, Breloer M.

Sci Rep. 2018 Jun 5;8(1):8636. doi: 10.1038/s41598-018-26907-2.


Nuclear Localization of Suppressor of Cytokine Signaling-1 Regulates Local Immunity in the Lung.

Zimmer J, Weitnauer M, Boutin S, Küblbeck G, Thiele S, Walker P, Lasitschka F, Lunding L, Orinska Z, Vock C, Arnold B, Wegmann M, Dalpke A.

Front Immunol. 2016 Nov 18;7:514. eCollection 2016.


High dose CD11c-driven IL15 is sufficient to drive NK cell maturation and anti-tumor activity in a trans-presentation independent manner.

Polansky JK, Bahri R, Divivier M, Duitman EH, Vock C, Goyeneche-Patino DA, Orinska Z, Bulfone-Paus S.

Sci Rep. 2016 Jan 29;6:19699. doi: 10.1038/srep19699.


CD252 regulates mast cell mediated, CD1d-restricted NKT-cell activation in mice.

Gonzalez Roldan N, Orinska Z, Ewers H, Bulfone-Paus S.

Eur J Immunol. 2016 Feb;46(2):432-9. doi: 10.1002/eji.201545879. Epub 2015 Dec 9.


miRNA-155 controls mast cell activation by regulating the PI3Kγ pathway and anaphylaxis in a mouse model.

Biethahn K, Orinska Z, Vigorito E, Goyeneche-Patino DA, Mirghomizadeh F, Föger N, Bulfone-Paus S.

Allergy. 2014 Jun;69(6):752-62. doi: 10.1111/all.12407. Epub 2014 Apr 15.


IL-33 causes selective mast cell tolerance to bacterial cell wall products by inducing IRAK1 degradation.

Sandig H, Jobbings CE, Roldan NG, Whittingham-Dowd JK, Orinska Z, Takeuchi O, Akira S, Bulfone-Paus S.

Eur J Immunol. 2013 Apr;43(4):979-88. doi: 10.1002/eji.201242786. Epub 2013 Mar 6.


Syntaxin 11 is required for NK and CD8⁺ T-cell cytotoxicity and neutrophil degranulation.

D'Orlando O, Zhao F, Kasper B, Orinska Z, Müller J, Hermans-Borgmeyer I, Griffiths GM, Zur Stadt U, Bulfone-Paus S.

Eur J Immunol. 2013 Jan;43(1):194-208. doi: 10.1002/eji.201142343. Epub 2012 Dec 12.


Ectonucleotidase CD38 demarcates regulatory, memory-like CD8+ T cells with IFN-γ-mediated suppressor activities.

Bahri R, Bollinger A, Bollinger T, Orinska Z, Bulfone-Paus S.

PLoS One. 2012;7(9):e45234. doi: 10.1371/journal.pone.0045234. Epub 2012 Sep 17.


Long-term bortezomib treatment reduces allergen-specific IgE but fails to ameliorate chronic asthma in mice.

Wegmann M, Lunding L, Orinska Z, Wong DM, Manz RA, Fehrenbach H.

Int Arch Allergy Immunol. 2012;158(1):43-53. doi: 10.1159/000330103. Epub 2011 Dec 29.


Differential regulation of mast cell degranulation versus cytokine secretion by the actin regulatory proteins Coronin1a and Coronin1b.

Föger N, Jenckel A, Orinska Z, Lee KH, Chan AC, Bulfone-Paus S.

J Exp Med. 2011 Aug 29;208(9):1777-87. doi: 10.1084/jem.20101757. Epub 2011 Aug 15.


Mechanisms of cytokine secretion: a portfolio of distinct pathways allows flexibility in cytokine activity.

Duitman EH, Orinska Z, Bulfone-Paus S.

Eur J Cell Biol. 2011 Jun-Jul;90(6-7):476-83. doi: 10.1016/j.ejcb.2011.01.010. Epub 2011 Mar 24. Review.


Retraction: Extracellular ATP induces cytokine expression and apoptosis through P2X7 receptor in murine mast cells.

Orinska Z, Hein M, Petersen F, Bulfone-Paus S, Thon L, Adam D.

J Immunol. 2011 Feb 15;186(4):2683. doi: 10.4049/jimmunol.1090144. No abstract available.


Retraction: Mast cells express novel functional IL-15 receptor α isoforms.

Krause H, Paus R, Orinska Z, Bulfone-Paus S.

J Immunol. 2011 Feb 15;186(4):2682. doi: 10.4049/jimmunol.1090143. No abstract available.


I787 provides signals for c-Kit receptor internalization and functionality that control mast cell survival and development.

Orinska Z, Föger N, Huber M, Marschall J, Mirghomizadeh F, Du X, Scheller M, Rosenstiel P, Goldmann T, Bollinger A, Beutler BA, Bulfone-Paus S.

Blood. 2010 Oct 14;116(15):2665-75. doi: 10.1182/blood-2009-06-228460. Epub 2010 Jul 1. Erratum in: Blood. 2011 Jun 30;117(26):7186.


Mast cell-mediated antigen presentation regulates CD8+ T cell effector functions.

Stelekati E, Bahri R, D'Orlando O, Orinska Z, Mittrücker HW, Langenhaun R, Glatzel M, Bollinger A, Paus R, Bulfone-Paus S.

Immunity. 2009 Oct 16;31(4):665-76. doi: 10.1016/j.immuni.2009.08.022. Epub 2009 Oct 8.


Transcriptional regulation of mouse mast cell protease-2 by interleukin-15.

Mirghomizadeh F, Bullwinkel J, Orinska Z, Janssen O, Petersen A, Singh PB, Bulfone-Paus S.

J Biol Chem. 2009 Nov 20;284(47):32635-41. doi: 10.1074/jbc.M109.015446. Epub 2009 Oct 1.


Survival and migration of human dendritic cells are regulated by an IFN-alpha-inducible Axl/Gas6 pathway.

Scutera S, Fraone T, Musso T, Cappello P, Rossi S, Pierobon D, Orinska Z, Paus R, Bulfone-Paus S, Giovarelli M.

J Immunol. 2009 Sep 1;183(5):3004-13. doi: 10.4049/jimmunol.0804384. Epub 2009 Aug 5.


Intracellular IL-15 controls mast cell survival.

Mirghomizadeh F, Winoto-Morbach S, Orinska Z, Lee KH, Schütze S, Bulfone-Paus S.

Exp Cell Res. 2009 Oct 15;315(17):3064-75. doi: 10.1016/j.yexcr.2009.07.019. Epub 2009 Jul 23.


ATP induces P2X7 receptor-independent cytokine and chemokine expression through P2X1 and P2X3 receptors in murine mast cells.

Bulanova E, Budagian V, Orinska Z, Koch-Nolte F, Haag F, Bulfone-Paus S.

J Leukoc Biol. 2009 Apr;85(4):692-702. doi: 10.1189/jlb.0808470. Epub 2009 Jan 21. Retraction in: J Leukoc Biol. 2011 Mar;89(3):489.


Deficiency of the tetraspanin CD63 associated with kidney pathology but normal lysosomal function.

Schröder J, Lüllmann-Rauch R, Himmerkus N, Pleines I, Nieswandt B, Orinska Z, Koch-Nolte F, Schröder B, Bleich M, Saftig P.

Mol Cell Biol. 2009 Feb;29(4):1083-94. doi: 10.1128/MCB.01163-08. Epub 2008 Dec 15.


How a cytokine is chaperoned through the secretory pathway by complexing with its own receptor: lessons from interleukin-15 (IL-15)/IL-15 receptor alpha.

Duitman EH, Orinska Z, Bulanova E, Paus R, Bulfone-Paus S.

Mol Cell Biol. 2008 Aug;28(15):4851-61. doi: 10.1128/MCB.02178-07. Epub 2008 May 27. Erratum in: Mol Cell Biol. 2010 May;30(10):2578.


IL-2 induces in vivo suppression by CD4(+)CD25(+)Foxp3(+) regulatory T cells.

Brandenburg S, Takahashi T, de la Rosa M, Janke M, Karsten G, Muzzulini T, Orinska Z, Bulfone-Paus S, Scheffold A.

Eur J Immunol. 2008 Jun;38(6):1643-53. doi: 10.1002/eji.200737791.


IL-15 constrains mast cell-dependent antibacterial defenses by suppressing chymase activities.

Orinska Z, Maurer M, Mirghomizadeh F, Bulanova E, Metz M, Nashkevich N, Schiemann F, Schulmistrat J, Budagian V, Giron-Michel J, Brandt E, Paus R, Bulfone-Paus S.

Nat Med. 2007 Aug;13(8):927-34. Epub 2007 Jul 22.


Mast cells in allergy: innate instructors of adaptive responses.

Stelekati E, Orinska Z, Bulfone-Paus S.

Immunobiology. 2007;212(6):505-19. Epub 2007 May 7. Review.


Soluble Interleukin IL-15Ralpha is generated by alternative splicing or proteolytic cleavage and forms functional complexes with IL-15.

Bulanova E, Budagian V, Duitman E, Orinska Z, Krause H, Rückert R, Reiling N, Bulfone-Paus S.

J Biol Chem. 2007 May 4;282(18):13167-79. Epub 2007 Feb 27. Retraction in: J Biol Chem. 2011 Feb 18;286(7):5934.


A promiscuous liaison between IL-15 receptor and Axl receptor tyrosine kinase in cell death control.

Budagian V, Bulanova E, Orinska Z, Thon L, Mamat U, Bellosta P, Basilico C, Adam D, Paus R, Bulfone-Paus S.

EMBO J. 2005 Dec 21;24(24):4260-70. Epub 2005 Nov 24. Retraction in: EMBO J. 2011 Feb 2;30(3):627.


Soluble Axl is generated by ADAM10-dependent cleavage and associates with Gas6 in mouse serum.

Budagian V, Bulanova E, Orinska Z, Duitman E, Brandt K, Ludwig A, Hartmann D, Lemke G, Saftig P, Bulfone-Paus S.

Mol Cell Biol. 2005 Nov;25(21):9324-39. Retraction in: Mol Cell Biol. 2011 Mar;31(6):1330.


TLR3-induced activation of mast cells modulates CD8+ T-cell recruitment.

Orinska Z, Bulanova E, Budagian V, Metz M, Maurer M, Bulfone-Paus S.

Blood. 2005 Aug 1;106(3):978-87. Epub 2005 Apr 19.


Extracellular ATP induces cytokine expression and apoptosis through P2X7 receptor in murine mast cells.

Bulanova E, Budagian V, Orinska Z, Hein M, Petersen F, Thon L, Adam D, Bulfone-Paus S.

J Immunol. 2005 Apr 1;174(7):3880-90. Retraction in: Orinska Z, Hein M, Petersen F, Bulfone-Paus S, Thon L, Adam D. J Immunol. 2011 Feb 15;186(4):2683.


Reverse signaling through membrane-bound interleukin-15.

Budagian V, Bulanova E, Orinska Z, Pohl T, Borden EC, Silverman R, Bulfone-Paus S.

J Biol Chem. 2004 Oct 1;279(40):42192-201. Epub 2004 Jul 28. Retraction in: J Biol Chem. 2011 Mar 11;286(10):8708.


Natural soluble interleukin-15Ralpha is generated by cleavage that involves the tumor necrosis factor-alpha-converting enzyme (TACE/ADAM17).

Budagian V, Bulanova E, Orinska Z, Ludwig A, Rose-John S, Saftig P, Borden EC, Bulfone-Paus S.

J Biol Chem. 2004 Sep 24;279(39):40368-75. Epub 2004 Jun 23. Retraction in: J Biol Chem. 2011 Mar 18;286(11):9894.


A regulatory role for CD37 in T cell proliferation.

van Spriel AB, Puls KL, Sofi M, Pouniotis D, Hochrein H, Orinska Z, Knobeloch KP, Plebanski M, Wright MD.

J Immunol. 2004 Mar 1;172(5):2953-61.


Mast cells express novel functional IL-15 receptor alpha isoforms.

Bulanova E, Budagian V, Orinska Z, Krause H, Paus R, Bulfone-Paus S.

J Immunol. 2003 May 15;170(10):5045-55. Retraction in: Krause H, Paus R, Orinska Z, Bulfone-Paus S. J Immunol. 2011 Feb 15;186(4):2682.


Novel B cell population producing functional IgG in the absence of membrane IgM expression.

Orinska Z, Osiak A, Löhler J, Bulanova E, Budagian V, Horak I, Bulfone-Paus S.

Eur J Immunol. 2002 Dec;32(12):3472-80.


Signaling through P2X7 receptor in human T cells involves p56lck, MAP kinases, and transcription factors AP-1 and NF-kappa B.

Budagian V, Bulanova E, Brovko L, Orinska Z, Fayad R, Paus R, Bulfone-Paus S.

J Biol Chem. 2003 Jan 17;278(3):1549-60. Epub 2002 Nov 6. Retraction in: J Biol Chem. 2011 Mar 18;286(11):9894.


Targeted inactivation of the tetraspanin CD37 impairs T-cell-dependent B-cell response under suboptimal costimulatory conditions.

Knobeloch KP, Wright MD, Ochsenbein AF, Liesenfeld O, Löhler J, Zinkernagel RM, Horak I, Orinska Z.

Mol Cell Biol. 2000 Aug;20(15):5363-9.


Binding of nerve growth factor to different forms of alpha 2-macroglobulin.

Keck K, Orinska Z, Waldschütz M.

Ann N Y Acad Sci. 1994 Sep 10;737:456-9. No abstract available.


Supplemental Content

Loading ...
Support Center