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Dual inhibition of angiopoietin-TIE2 and MET alters the tumor microenvironment and prolongs survival in a metastatic model of renal cell carcinoma.

Elbanna M, Orillion AR, Damayanti NP, Adelaiye-Ogala R, Shen L, Miles KM, Chintala S, Ciamporcero E, Ramakrishnan S, Ku SY, Rex K, Caenepeel S, Coxon A, Pili R.

Mol Cancer Ther. 2019 Oct 3. pii: molcanther.1202.2018. doi: 10.1158/1535-7163.MCT-18-1202. [Epub ahead of print]


Therapeutic Targeting of Sunitinib-Induced AR Phosphorylation in Renal Cell Carcinoma.

Adelaiye-Ogala R, Damayanti NP, Orillion AR, Arisa S, Chintala S, Titus MA, Kao C, Pili R.

Cancer Res. 2018 Jun 1;78(11):2886-2896. doi: 10.1158/0008-5472.CAN-17-3386. Epub 2018 Mar 23.


PTPN14 forms a complex with Kibra and LATS1 proteins and negatively regulates the YAP oncogenic function.

Wilson KE, Li YW, Yang N, Shen H, Orillion AR, Zhang J.

J Biol Chem. 2014 Aug 22;289(34):23693-700. doi: 10.1074/jbc.M113.534701. Epub 2014 Jul 14.

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