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Items: 1 to 50 of 87

1.

Quantifying compartment-associated variations of protein abundance in proteomics data.

Parca L, Beck M, Bork P, Ori A.

Mol Syst Biol. 2018 Jul 2;14(7):e8131. doi: 10.15252/msb.20178131.

2.

Cellular and epigenetic drivers of stem cell ageing.

Ermolaeva M, Neri F, Ori A, Rudolph KL.

Nat Rev Mol Cell Biol. 2018 Jun 1. doi: 10.1038/s41580-018-0020-3. [Epub ahead of print] Review.

PMID:
29858605
3.

Transcriptome analysis in whole blood reveals increased microbial diversity in schizophrenia.

Olde Loohuis LM, Mangul S, Ori APS, Jospin G, Koslicki D, Yang HT, Wu T, Boks MP, Lomen-Hoerth C, Wiedau-Pazos M, Cantor RM, de Vos WM, Kahn RS, Eskin E, Ophoff RA.

Transl Psychiatry. 2018 May 10;8(1):96. doi: 10.1038/s41398-018-0107-9.

4.

NUFIP1 is a ribosome receptor for starvation-induced ribophagy.

Wyant GA, Abu-Remaileh M, Frenkel EM, Laqtom NN, Dharamdasani V, Lewis CA, Chan SH, Heinze I, Ori A, Sabatini DM.

Science. 2018 May 18;360(6390):751-758. doi: 10.1126/science.aar2663. Epub 2018 Apr 26.

PMID:
29700228
5.

Spatial Tissue Proteomics Quantifies Inter- and Intratumor Heterogeneity in Hepatocellular Carcinoma (HCC).

Buczak K, Ori A, Kirkpatrick JM, Holzer K, Dauch D, Roessler S, Endris V, Lasitschka F, Parca L, Schmidt A, Zender L, Schirmacher P, Krijgsveld J, Singer S, Beck M.

Mol Cell Proteomics. 2018 Apr;17(4):810-825. doi: 10.1074/mcp.RA117.000189. Epub 2018 Jan 23.

6.

Landscape of nuclear transport receptor cargo specificity.

Mackmull MT, Klaus B, Heinze I, Chokkalingam M, Beyer A, Russell RB, Ori A, Beck M.

Mol Syst Biol. 2017 Dec 18;13(12):962. doi: 10.15252/msb.20177608.

7.

What have we learned on aging from omics studies?

Cellerino A, Ori A.

Semin Cell Dev Biol. 2017 Oct;70:177-189. doi: 10.1016/j.semcdb.2017.06.012. Epub 2017 Jun 16. Review.

PMID:
28630026
8.

Renormalized Stress-Energy Tensor of an Evaporating Spinning Black Hole.

Levi A, Eilon E, Ori A, van de Meent M.

Phys Rev Lett. 2017 Apr 7;118(14):141102. doi: 10.1103/PhysRevLett.118.141102. Epub 2017 Apr 7.

PMID:
28430496
9.

Summaries of plenary and selected symposia sessions at the XXIV World Congress of Psychiatric Genetics; Jerusalem, Israel; 30 October 2016-3 November 2016.

Ciobanu LG, Ori AP, Pagliaroli L, Polimanti R, Spindola LM, Vincent JB, Cormack FK.

Psychiatr Genet. 2017 Apr;27(2):41-53. doi: 10.1097/YPG.0000000000000167.

PMID:
28212207
10.

Versatile Method for Renormalized Stress-Energy Computation in Black-Hole Spacetimes.

Levi A, Ori A.

Phys Rev Lett. 2016 Dec 2;117(23):231101. Epub 2016 Nov 30.

PMID:
27982648
11.

Architecture of the yeast Elongator complex.

Dauden MI, Kosinski J, Kolaj-Robin O, Desfosses A, Ori A, Faux C, Hoffmann NA, Onuma OF, Breunig KD, Beck M, Sachse C, Séraphin B, Glatt S, Müller CW.

EMBO Rep. 2017 Feb;18(2):264-279. doi: 10.15252/embr.201643353. Epub 2016 Dec 14.

12.

Proteomic Analysis Reveals GMP Synthetase as p53 Repression Target in Liver Cancer.

Holzer K, Drucker E, Roessler S, Dauch D, Heinzmann F, Waldburger N, Eiteneuer EM, Herpel E, Breuhahn K, Zender L, Schirmacher P, Ori A, Singer S.

Am J Pathol. 2017 Feb;187(2):228-235. doi: 10.1016/j.ajpath.2016.09.022. Epub 2016 Dec 7.

PMID:
27939741
13.

The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.

Scharaw S, Iskar M, Ori A, Boncompain G, Laketa V, Poser I, Lundberg E, Perez F, Beck M, Bork P, Pepperkok R.

J Cell Biol. 2016 Nov 21;215(4):543-558. Epub 2016 Nov 8.

14.

Structure of the ribosome post-recycling complex probed by chemical cross-linking and mass spectrometry.

Kiosze-Becker K, Ori A, Gerovac M, Heuer A, Nürenberg-Goloub E, Rashid UJ, Becker T, Beckmann R, Beck M, Tampé R.

Nat Commun. 2016 Nov 8;7:13248. doi: 10.1038/ncomms13248.

15.

Gender differences in the adverse events' profile registered in seven observational studies of a wide gender-medicine (MetaGeM) project: the MetaGeM safety analysis.

Colombo D, Zagni E, Nica M, Rizzoli S, Ori A, Bellia G.

Drug Des Devel Ther. 2016 Sep 13;10:2917-2927. eCollection 2016.

16.

Structure-Function Correlation of Aminated Poly(α)glutamate as siRNA Nanocarriers.

Krivitsky A, Polyak D, Scomparin A, Eliyahu S, Ori A, Avkin-Nachum S, Krivitsky V, Satchi-Fainaro R.

Biomacromolecules. 2016 Sep 12;17(9):2787-800. doi: 10.1021/acs.biomac.6b00555. Epub 2016 Aug 2.

PMID:
27377188
17.

Integrated Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration in Old Rats.

Ori A, Toyama BH, Harris MS, Bock T, Iskar M, Bork P, Ingolia NT, Hetzer MW, Beck M.

Cell Syst. 2015 Sep 23;1(3):224-37. doi: 10.1016/j.cels.2015.08.012. Epub 2015 Sep 17.

18.

Automated structure modeling of large protein assemblies using crosslinks as distance restraints.

Ferber M, Kosinski J, Ori A, Rashid UJ, Moreno-Morcillo M, Simon B, Bouvier G, Batista PR, Müller CW, Beck M, Nilges M.

Nat Methods. 2016 Jun;13(6):515-20. doi: 10.1038/nmeth.3838. Epub 2016 Apr 25.

PMID:
27111507
19.

Cellular apoptosis susceptibility (CAS) is linked to integrin β1 and required for tumor cell migration and invasion in hepatocellular carcinoma (HCC).

Winkler J, Roessler S, Sticht C, DiGuilio AL, Drucker E, Holzer K, Eiteneuer E, Herpel E, Breuhahn K, Gretz N, Schirmacher P, Ori A, Singer S.

Oncotarget. 2016 Apr 19;7(16):22883-92. doi: 10.18632/oncotarget.8256.

20.

Spatiotemporal variation of mammalian protein complex stoichiometries.

Ori A, Iskar M, Buczak K, Kastritis P, Parca L, Andrés-Pons A, Singer S, Bork P, Beck M.

Genome Biol. 2016 Mar 14;17:47. doi: 10.1186/s13059-016-0912-5.

21.

Efficacy of cyclosporine A as monotherapy in patients with psoriatic arthritis: a subgroup analysis of the SYNERGY Study.

Colombo D, Chimenti S, Grossi PA, Marchesoni A, Foti R, Calzavara-Pinton P, Zagni E, Ori A, Bellia G; SYNERGY Study Group.

G Ital Dermatol Venereol. 2017 Jun;152(3):297-301. doi: 10.23736/S0392-0488.16.05301-3. Epub 2016 Feb 2.

PMID:
26837484
22.

Characterization and quantification of proteins secreted by single human embryos prior to implantation.

Poli M, Ori A, Child T, Jaroudi S, Spath K, Beck M, Wells D.

EMBO Mol Med. 2015 Nov;7(11):1465-79. doi: 10.15252/emmm.201505344.

23.

In situ structural analysis of the human nuclear pore complex.

von Appen A, Kosinski J, Sparks L, Ori A, DiGuilio AL, Vollmer B, Mackmull MT, Banterle N, Parca L, Kastritis P, Buczak K, Mosalaganti S, Hagen W, Andres-Pons A, Lemke EA, Bork P, Antonin W, Glavy JS, Bui KH, Beck M.

Nature. 2015 Oct 1;526(7571):140-143. doi: 10.1038/nature15381. Epub 2015 Sep 23.

24.

Adherence to AIOM (Italian Association of Medical Oncology) lung cancer guidelines in Italian clinical practice: Results from the RIGHT-3 (research for the identification of the most effective and highly accepted clinical guidelines for cancer treatment) study.

Barni S, Maiello E, Di Maio M, Ardizzoni A, Cappuzzo F, Maranzano E, Novello S, Bennati C, Ori A, Rizzoli S, Crinò L; RIGHT-3 study group.

Lung Cancer. 2015 Nov;90(2):234-42. doi: 10.1016/j.lungcan.2015.08.005. Epub 2015 Aug 19.

25.

Genome-wide burden of deleterious coding variants increased in schizophrenia.

Loohuis LM, Vorstman JA, Ori AP, Staats KA, Wang T, Richards AL, Leonenko G, Walters JT, DeYoung J; GROUP Consortium, Cantor RM, Ophoff RA.

Nat Commun. 2015 Jul 9;6:7501. doi: 10.1038/ncomms8501.

26.

Prevalence and associated features of self-reported freezing of gait in Parkinson disease: The DEEP FOG study.

Amboni M, Stocchi F, Abbruzzese G, Morgante L, Onofrj M, Ruggieri S, Tinazzi M, Zappia M, Attar M, Colombo D, Simoni L, Ori A, Barone P, Antonini A; DEEP Study Group.

Parkinsonism Relat Disord. 2015 Jun;21(6):644-9. doi: 10.1016/j.parkreldis.2015.03.028. Epub 2015 Apr 13.

PMID:
25899545
27.

Symportin 1 chaperones 5S RNP assembly during ribosome biogenesis by occupying an essential rRNA-binding site.

Calviño FR, Kharde S, Ori A, Hendricks A, Wild K, Kressler D, Bange G, Hurt E, Beck M, Sinning I.

Nat Commun. 2015 Apr 7;6:6510. doi: 10.1038/ncomms7510.

28.

Histone Deacetylase Inhibitors (HDACi) Cause the Selective Depletion of Bromodomain Containing Proteins (BCPs).

Mackmull MT, Iskar M, Parca L, Singer S, Bork P, Ori A, Beck M.

Mol Cell Proteomics. 2015 May;14(5):1350-60. doi: 10.1074/mcp.M114.042499. Epub 2015 Mar 9.

29.

Genome-wide association study of NMDA receptor coagonists in human cerebrospinal fluid and plasma.

Luykx JJ, Bakker SC, Visser WF, Verhoeven-Duif N, Buizer-Voskamp JE, den Heijer JM, Boks MP, Sul JH, Eskin E, Ori AP, Cantor RM, Vorstman J, Strengman E, DeYoung J, Kappen TH, Pariama E, van Dongen EP, Borgdorff P, Bruins P, de Koning TJ, Kahn RS, Ophoff RA.

Mol Psychiatry. 2015 Dec;20(12):1557-64. doi: 10.1038/mp.2014.190. Epub 2015 Feb 10.

PMID:
25666758
30.

Xlink Analyzer: software for analysis and visualization of cross-linking data in the context of three-dimensional structures.

Kosinski J, von Appen A, Ori A, Karius K, Müller CW, Beck M.

J Struct Biol. 2015 Mar;189(3):177-83. doi: 10.1016/j.jsb.2015.01.014. Epub 2015 Feb 7.

31.

Structural basis for assembly and function of the Nup82 complex in the nuclear pore scaffold.

Gaik M, Flemming D, von Appen A, Kastritis P, Mücke N, Fischer J, Stelter P, Ori A, Bui KH, Baßler J, Barbar E, Beck M, Hurt E.

J Cell Biol. 2015 Feb 2;208(3):283-97. doi: 10.1083/jcb.201411003.

32.

Clinical variables associated with treatment changes in Parkinson's disease: results from the longitudinal phase of the REASON study.

Abbruzzese G, Barone P, Ceravolo R, Fabbrini G, Lessi P, Ori A, Simoni L, Tinazzi M, Antonini A.

Neurol Sci. 2015 Jun;36(6):935-43. doi: 10.1007/s10072-014-2060-6. Epub 2015 Jan 7.

PMID:
25564417
33.

An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum.

Bock T, Chen WH, Ori A, Malik N, Silva-Martin N, Huerta-Cepas J, Powell ST, Kastritis PL, Smyshlyaev G, Vonkova I, Kirkpatrick J, Doerks T, Nesme L, Baßler J, Kos M, Hurt E, Carlomagno T, Gavin AC, Barabas O, Müller CW, van Noort V, Beck M, Bork P.

Nucleic Acids Res. 2014 Dec 16;42(22):13525-33. doi: 10.1093/nar/gku1147. Epub 2014 Nov 14.

34.

An Italian Oncology Research to Evaluate Adherence to Clinical Guidelines for Cancer Treatment: The Right Program.

Sgarbi S, Simoni L, Ori A, Fiori GG, Maiello E, Barni S.

Value Health. 2014 Nov;17(7):A653. doi: 10.1016/j.jval.2014.08.2378. Epub 2014 Oct 26. No abstract available.

35.

Cost and Duration Of Regulatory Process in an Observational Study in Europe and USA.

Ori A, Fiori GG, Fernandez S, Longo D, Simoni L.

Value Health. 2014 Nov;17(7):A453. doi: 10.1016/j.jval.2014.08.1229. Epub 2014 Oct 26. No abstract available.

36.

Proliferation and migration activities of fibroblast growth factor-2 in endothelial cells are modulated by its direct interaction with heparin affin regulatory peptide.

Dos Santos C, Blanc C, Elahouel R, Prescott M, Carpentier G, Ori A, Courty J, Hamma-Kourbali Y, Fernig DG, Delbé J.

Biochimie. 2014 Dec;107 Pt B:350-7. doi: 10.1016/j.biochi.2014.10.002. Epub 2014 Oct 12.

PMID:
25315978
37.

Characterisation of the interaction of neuropilin-1 with heparin and a heparan sulfate mimetic library of heparin-derived sugars.

Uniewicz KA, Ori A, Ahmed YA, Yates EA, Fernig DG.

PeerJ. 2014 Jun 26;2:e461. doi: 10.7717/peerj.461. eCollection 2014.

38.

The use of targeted proteomics to determine the stoichiometry of large macromolecular assemblies.

Ori A, Andrés-Pons A, Beck M.

Methods Cell Biol. 2014;122:117-46. doi: 10.1016/B978-0-12-417160-2.00006-0.

PMID:
24857728
39.

Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits.

Piazza I, Rutkowska A, Ori A, Walczak M, Metz J, Pelechano V, Beck M, Haering CH.

Nat Struct Mol Biol. 2014 Jun;21(6):560-8. doi: 10.1038/nsmb.2831. Epub 2014 May 18.

PMID:
24837193
40.

Prosurvival function of the cellular apoptosis susceptibility/importin-α1 transport cycle is repressed by p53 in liver cancer.

Winkler J, Ori A, Holzer K, Sticht C, Dauch D, Eiteneuer EM, Pinna F, Geffers R, Ehemann V, Andres-Pons A, Breuhahn K, Longerich T, Bermejo JL, Gretz N, Zender L, Schirmacher P, Beck M, Singer S.

Hepatology. 2014 Sep;60(3):884-95. doi: 10.1002/hep.27207. Epub 2014 Jul 17.

PMID:
24799195
41.

Integrated structural analysis of the human nuclear pore complex scaffold.

Bui KH, von Appen A, DiGuilio AL, Ori A, Sparks L, Mackmull MT, Bock T, Hagen W, Andrés-Pons A, Glavy JS, Beck M.

Cell. 2013 Dec 5;155(6):1233-43. doi: 10.1016/j.cell.2013.10.055.

42.

Low levels of low-density lipoprotein cholesterol: a negative predictor of survival in elderly patients with advanced heart failure.

Charach G, Rabinovich A, Ori A, Weksler D, Sheps D, Charach L, Weintraub M, George J.

Cardiology. 2014;127(1):45-50. doi: 10.1159/000355164. Epub 2013 Nov 5.

43.

Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines.

Ori A, Banterle N, Iskar M, Andrés-Pons A, Escher C, Khanh Bui H, Sparks L, Solis-Mezarino V, Rinner O, Bork P, Lemke EA, Beck M.

Mol Syst Biol. 2013;9:648. doi: 10.1038/msb.2013.4.

44.

Diversification of the structural determinants of fibroblast growth factor-heparin interactions: implications for binding specificity.

Xu R, Ori A, Rudd TR, Uniewicz KA, Ahmed YA, Guimond SE, Skidmore MA, Siligardi G, Yates EA, Fernig DG.

J Biol Chem. 2012 Nov 16;287(47):40061-73. doi: 10.1074/jbc.M112.398826. Epub 2012 Sep 27.

45.

A gene co-expression network in whole blood of schizophrenia patients is independent of antipsychotic-use and enriched for brain-expressed genes.

de Jong S, Boks MP, Fuller TF, Strengman E, Janson E, de Kovel CG, Ori AP, Vi N, Mulder F, Blom JD, Glenthøj B, Schubart CD, Cahn W, Kahn RS, Horvath S, Ophoff RA.

PLoS One. 2012;7(6):e39498. doi: 10.1371/journal.pone.0039498. Epub 2012 Jun 27.

46.

Following protein-glycosaminoglycan polysaccharide interactions with differential scanning fluorimetry.

Uniewicz KA, Ori A, Rudd TR, Guerrini M, Wilkinson MC, Fernig DG, Yates EA.

Methods Mol Biol. 2012;836:171-82. doi: 10.1007/978-1-61779-498-8_12.

PMID:
22252635
47.

The quantitative proteome of a human cell line.

Beck M, Schmidt A, Malmstroem J, Claassen M, Ori A, Szymborska A, Herzog F, Rinner O, Ellenberg J, Aebersold R.

Mol Syst Biol. 2011 Nov 8;7:549. doi: 10.1038/msb.2011.82.

48.

A systems biology approach for the investigation of the heparin/heparan sulfate interactome.

Ori A, Wilkinson MC, Fernig DG.

J Biol Chem. 2011 Jun 3;286(22):19892-904. doi: 10.1074/jbc.M111.228114. Epub 2011 Mar 30.

49.

Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships.

Rudd TR, Uniewicz KA, Ori A, Guimond SE, Skidmore MA, Gaudesi D, Xu R, Turnbull JE, Guerrini M, Torri G, Siligardi G, Wilkinson MC, Fernig DG, Yates EA.

Org Biomol Chem. 2010 Dec 7;8(23):5390-7. doi: 10.1039/c0ob00246a. Epub 2010 Sep 3.

PMID:
20865198
50.

Intravital two-photon microscopy assessment of renal protection efficacy of siRNA for p53 in experimental rat kidney transplantation models.

Imamura R, Isaka Y, Sandoval RM, Ori A, Adamsky S, Feinstein E, Molitoris BA, Takahara S.

Cell Transplant. 2010;19(12):1659-70. doi: 10.3727/096368910X516619. Epub 2010 Aug 17.

PMID:
20719069

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