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Items: 30


Improving the Timeliness of Chemotherapy Administration in the Bone Marrow Transplant Unit.

Bhandari R, Orgel E, Rushing T, Malicse K, Evangelista V, Jodele S, Dandoy CE.

Biol Blood Marrow Transplant. 2019 Sep 25. pii: S1083-8791(19)30637-8. doi: 10.1016/j.bbmt.2019.09.026. [Epub ahead of print]


Mechanisms by Which Obesity Impacts Survival from Acute Lymphoblastic Leukemia.

Orgel E, Sea JL, Mittelman SD.

J Natl Cancer Inst Monogr. 2019 Sep 1;2019(54):152-156. doi: 10.1093/jncimonographs/lgz020.


Levocarnitine does not impair chemotherapy cytotoxicity against acute lymphoblastic leukemia.

Sea JL, Orgel E, Chen T, Paszkiewicz RL, Krall AS, Oberley MJ, Stiles L, Mittelman SD.

Leuk Lymphoma. 2019 Sep 16:1-9. doi: 10.1080/10428194.2019.1666379. [Epub ahead of print]


Myosteatosis in adolescents and young adults treated for acute lymphoblastic leukemia.

Mueske NM, Mittelman SD, Wren TAL, Gilsanz V, Orgel E.

Leuk Lymphoma. 2019 Jul 2:1-8. doi: 10.1080/10428194.2019.1623889. [Epub ahead of print]


Recommendations for ototoxicity surveillance for childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCare Consortium.

Clemens E, van den Heuvel-Eibrink MM, Mulder RL, Kremer LCM, Hudson MM, Skinner R, Constine LS, Bass JK, Kuehni CE, Langer T, van Dalen EC, Bardi E, Bonne NX, Brock PR, Brooks B, Carleton B, Caron E, Chang KW, Johnston K, Knight K, Nathan PC, Orgel E, Prasad PK, Rottenberg J, Scheinemann K, de Vries ACH, Walwyn T, Weiss A, Am Zehnhoff-Dinnesen A, Cohn RJ, Landier W; International Guideline Harmonization Group ototoxicity group.

Lancet Oncol. 2019 Jan;20(1):e29-e41. doi: 10.1016/S1470-2045(18)30858-1. Review.


The genetic basis and cell of origin of mixed phenotype acute leukaemia.

Alexander TB, Gu Z, Iacobucci I, Dickerson K, Choi JK, Xu B, Payne-Turner D, Yoshihara H, Loh ML, Horan J, Buldini B, Basso G, Elitzur S, de Haas V, Zwaan CM, Yeoh A, Reinhardt D, Tomizawa D, Kiyokawa N, Lammens T, De Moerloose B, Catchpoole D, Hori H, Moorman A, Moore AS, Hrusak O, Meshinchi S, Orgel E, Devidas M, Borowitz M, Wood B, Heerema NA, Carrol A, Yang YL, Smith MA, Davidsen TM, Hermida LC, Gesuwan P, Marra MA, Ma Y, Mungall AJ, Moore RA, Jones SJM, Valentine M, Janke LJ, Rubnitz JE, Pui CH, Ding L, Liu Y, Zhang J, Nichols KE, Downing JR, Cao X, Shi L, Pounds S, Newman S, Pei D, Guidry Auvil JM, Gerhard DS, Hunger SP, Inaba H, Mullighan CG.

Nature. 2018 Oct;562(7727):373-379. doi: 10.1038/s41586-018-0436-0. Epub 2018 Sep 12.


Adipocyte metabolism of the chemotherapy daunorubicin.

Mittelman SD, Orgel E.

Oncoscience. 2018 Jun 25;5(5-6):146-147. doi: 10.18632/oncoscience.428. eCollection 2018 May. No abstract available.


Obesity and risk for venous thromboembolism from contemporary therapy for pediatric acute lymphoblastic leukemia.

Prasca S, Carmona R, Ji L, Ko RH, Bhojwani D, Rawlins YA, Mittelman SD, Young G, Orgel E.

Thromb Res. 2018 May;165:44-50. doi: 10.1016/j.thromres.2018.02.150. Epub 2018 Mar 2.


Therapy for children and adults with mixed phenotype acute leukemia: a systematic review and meta-analysis.

Maruffi M, Sposto R, Oberley MJ, Kysh L, Orgel E.

Leukemia. 2018 Jul;32(7):1515-1528. doi: 10.1038/s41375-018-0058-4. Epub 2018 Feb 27.


Predictors of hepatotoxicity and pancreatitis in children and adolescents with acute lymphoblastic leukemia treated according to contemporary regimens.

Denton CC, Rawlins YA, Oberley MJ, Bhojwani D, Orgel E.

Pediatr Blood Cancer. 2018 Mar;65(3). doi: 10.1002/pbc.26891. Epub 2017 Dec 8.


TACL'ing supportive care needs in pediatric early phase clinical trials for acute leukemia: A report from the therapeutic advances in childhood leukemia & lymphoma (TACL) consortium supportive care committee.

Orgel E, Auletta JJ.

Pediatr Hematol Oncol. 2017 Sep - Oct;34(6-7):409-417. doi: 10.1080/08880018.2017.1395936. Epub 2017 Nov 30. Review.


Adipocytes Sequester and Metabolize the Chemotherapeutic Daunorubicin.

Sheng X, Parmentier JH, Tucci J, Pei H, Cortez-Toledo O, Dieli-Conwright CM, Oberley MJ, Neely M, Orgel E, Louie SG, Mittelman SD.

Mol Cancer Res. 2017 Dec;15(12):1704-1713. doi: 10.1158/1541-7786.MCR-17-0338. Epub 2017 Nov 8.


Association of clinical trial enrollment and survival using contemporary therapy for pediatric acute lymphoblastic leukemia.

Moke DJ, Oberley MJ, Bhojwani D, Parekh C, Orgel E.

Pediatr Blood Cancer. 2018 Feb;65(2). doi: 10.1002/pbc.26788. Epub 2017 Sep 6.


Clinical Significance of Isolated Myeloperoxidase Expression in Pediatric B-Lymphoblastic Leukemia.

Oberley MJ, Li S, Orgel E, Phei Wee C, Hagiya A, O'Gorman MRG.

Am J Clin Pathol. 2017 Apr 1;147(4):374-381. doi: 10.1093/ajcp/aqx021. Erratum in: Am J Clin Pathol. 2017 Sep 1;148(3):280.


A randomized controlled trial testing an adherence-optimized Vitamin D regimen to mitigate bone change in adolescents being treated for acute lymphoblastic leukemia.

Orgel E, Mueske NM, Sposto R, Gilsanz V, Wren TAL, Freyer DR, Butturini AM, Mittelman SD.

Leuk Lymphoma. 2017 Oct;58(10):2370-2378. doi: 10.1080/10428194.2017.1289526. Epub 2017 Feb 20.


Treatment-related adverse events associated with a modified UK ALLR3 induction chemotherapy backbone for childhood relapsed/refractory acute lymphoblastic leukemia.

Sun W, Orgel E, Malvar J, Sposto R, Wilkes JJ, Gardner R, Tolbert VP, Smith A, Hur M, Hoffman J, Rheingold SR, Burke MJ, Wayne AS.

Pediatr Blood Cancer. 2016 Nov;63(11):1943-8. doi: 10.1002/pbc.26129. Epub 2016 Jul 20.


Association of body mass index and survival in pediatric leukemia: a meta-analysis.

Orgel E, Genkinger JM, Aggarwal D, Sung L, Nieder M, Ladas EJ.

Am J Clin Nutr. 2016 Mar;103(3):808-17. doi: 10.3945/ajcn.115.124586. Epub 2016 Feb 10.


Early injury to cortical and cancellous bone from induction chemotherapy for adolescents and young adults treated for acute lymphoblastic leukemia.

Orgel E, Mueske NM, Wren TA, Gilsanz V, Butturini AM, Freyer DR, Mittelman SD.

Bone. 2016 Apr;85:131-7. doi: 10.1016/j.bone.2016.01.027. Epub 2016 Feb 3.


Limitations of body mass index to assess body composition due to sarcopenic obesity during leukemia therapy.

Orgel E, Mueske NM, Sposto R, Gilsanz V, Freyer DR, Mittelman SD.

Leuk Lymphoma. 2018 Jan;59(1):138-145. doi: 10.3109/10428194.2015.1136741. Epub 2016 Jan 27.


Effect of Sensorineural Hearing Loss on Neurocognitive Functioning in Pediatric Brain Tumor Survivors.

Orgel E, O'Neil SH, Kayser K, Smith B, Softley TL, Sherman-Bien S, Counts PA, Murphy D, Dhall G, Freyer DR.

Pediatr Blood Cancer. 2016 Mar;63(3):527-34. doi: 10.1002/pbc.25804. Epub 2015 Nov 3.


Clinical and microbiologic outcomes of quinolone prophylaxis in children with acute myeloid leukemia.

Felsenstein S, Orgel E, Rushing T, Fu C, Hoffman JA.

Pediatr Infect Dis J. 2015 Apr;34(4):e78-84. doi: 10.1097/INF.0000000000000591.


Obesity is associated with residual leukemia following induction therapy for childhood B-precursor acute lymphoblastic leukemia.

Orgel E, Tucci J, Alhushki W, Malvar J, Sposto R, Fu CH, Freyer DR, Abdel-Azim H, Mittelman SD.

Blood. 2014 Dec 18;124(26):3932-8. doi: 10.1182/blood-2014-08-595389. Epub 2014 Oct 27.


Impact on survival and toxicity by duration of weight extremes during treatment for pediatric acute lymphoblastic leukemia: A report from the Children's Oncology Group.

Orgel E, Sposto R, Malvar J, Seibel NL, Ladas E, Gaynon PS, Freyer DR.

J Clin Oncol. 2014 May 1;32(13):1331-7. doi: 10.1200/JCO.2013.52.6962. Epub 2014 Mar 31.


Infectious morbidity by catheter type in neutropenic children with cancer.

Orgel E, Ji L, Pastor W, Schore RJ.

Pediatr Infect Dis J. 2014 Mar;33(3):263-6. doi: 10.1097/INF.0000000000000060.


Why Healthcare Providers Should Focus on the Fertility of AYA Cancer Survivors: It's Not Too Late!

Murphy D, Orgel E, Termuhlen A, Shannon S, Warren K, Quinn GP.

Front Oncol. 2013 Oct 7;3:248. doi: 10.3389/fonc.2013.00248. Review.


Efficacy and tolerability of intravenous pentamidine isethionate for Pneumocystis jiroveci prophylaxis in a pediatric oncology population.

Orgel E, Rushing T.

Pediatr Infect Dis J. 2014 Mar;33(3):319-21. doi: 10.1097/INF.0000000000000044.


Early cardiac outcomes following contemporary treatment for childhood acute myeloid leukemia: a North American perspective.

Orgel E, Zung L, Ji L, Finklestein J, Feusner J, Freyer DR.

Pediatr Blood Cancer. 2013 Sep;60(9):1528-33. doi: 10.1002/pbc.24498. Epub 2013 Feb 25.


The links between insulin resistance, diabetes, and cancer.

Orgel E, Mittelman SD.

Curr Diab Rep. 2013 Apr;13(2):213-22. doi: 10.1007/s11892-012-0356-6. Review.


Hearing loss among survivors of childhood brain tumors treated with an irradiation-sparing approach.

Orgel E, Jain S, Ji L, Pollick L, Si S, Finlay J, Freyer DR.

Pediatr Blood Cancer. 2012 Jun;58(6):953-8. doi: 10.1002/pbc.23275. Epub 2011 Jul 27.


A failing medical educational model: a self-assessment by physicians at all levels of training of ability and comfort to deliver bad news.

Orgel E, McCarter R, Jacobs S.

J Palliat Med. 2010 Jun;13(6):677-83. doi: 10.1089/jpm.2009.0338.


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