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Items: 1 to 50 of 92

1.

Longitudinal evaluation of glucocorticoid receptor alpha/beta expression and signalling, adrenocortical function and cytokines in critically ill steroid-free patients.

Vassiliou AG, Stamogiannos G, Jahaj E, Botoula E, Floros G, Vassiliadi DA, Ilias I, Tsagarakis S, Tzanela M, Orfanos SE, Kotanidou A, Dimopoulou I.

Mol Cell Endocrinol. 2019 Nov 19;501:110656. doi: 10.1016/j.mce.2019.110656. [Epub ahead of print]

PMID:
31756425
2.

Systemic endothelial glycocalyx and aortic stiffness are preserved in pulmonary arterial hypertension.

Triantafyllidi H, Apostolopoulou O, Benas D, Ikonomidis I, Varoudi M, Tsagkaris I, Anthi A, Rallidis L, Kostantonis D, Frantzeskaki F, Pavlidis G, Palaiodimos L, Schoinas A, Armaganidis A, Lekakis J, Orfanos SE.

Hellenic J Cardiol. 2019 Nov 15. pii: S1109-9666(19)30280-5. doi: 10.1016/j.hjc.2019.10.006. [Epub ahead of print] No abstract available.

3.

Epidemiology and initial management of pulmonary arterial hypertension: real-world data from the Hellenic pulmOnary hyPertension rEgistry (HOPE).

Arvanitaki A, Boutsikou M, Anthi A, Apostolopoulou S, Avgeropoulou A, Demerouti E, Farmakis D, Feloukidis C, Giannakoulas G, Karvounis H, Karyofyllis P, Mitrouska I, Mouratoglou S, Naka KK, Orfanos SE, Panagiotidou E, Pitsiou G, Rammos S, Stagaki E, Stanopoulos I, Thomaidi A, Triantafyllidi H, Tsangaris I, Tsiapras D, Voudris V, Manginas A; Hellenic Society for the Study of Pulmonary Hypertension (HSSPH).

Pulm Circ. 2019 Oct 14;9(3):2045894019877157. doi: 10.1177/2045894019877157. eCollection 2019 Jul-Sep.

4.

Pulmonary capillary surface area in supine exercising humans: demonstration of vascular recruitment.

Langleben D, Orfanos SE, Giovinazzo M, Schlesinger RD, Naeije R, Fox BD, Abualsaud AO, Blenkhorn F, Rudski LG, Catravas JD.

Am J Physiol Lung Cell Mol Physiol. 2019 Sep 1;317(3):L361-L368. doi: 10.1152/ajplung.00098.2019. Epub 2019 Jun 26.

PMID:
31242024
5.

Decreased glucocorticoid receptor expression during critical illness.

Vassiliou AG, Floros G, Jahaj E, Stamogiannos G, Gennimata S, Vassiliadi DA, Tsagarakis S, Tzanela M, Ilias I, Orfanos SE, Kotanidou A, Dimopoulou I.

Eur J Clin Invest. 2019 Apr;49(4):e13073. doi: 10.1111/eci.13073. Epub 2019 Feb 18.

PMID:
30703253
6.

Platelet and coagulation disorders in newly diagnosed patients with pulmonary arterial hypertension.

Vrigkou E, Tsangaris I, Bonovas S, Kopterides P, Kyriakou E, Konstantonis D, Pappas A, Anthi A, Gialeraki A, Orfanos SE, Armaganidis A, Tsantes A.

Platelets. 2019;30(5):646-651. doi: 10.1080/09537104.2018.1499890. Epub 2018 Jul 26.

PMID:
30047809
7.

Treating nosocomial pneumonia: what's new.

Frantzeskaki F, Orfanos SE.

ERJ Open Res. 2018 Jun 26;4(2). pii: 00058-2018. doi: 10.1183/23120541.00058-2018. eCollection 2018 Apr.

8.

Early increase of VEGF-A is associated with resolution of ventilator-associated pneumonia: Clinical and experimental evidence.

Strouvalis I, Routsi C, Adamopoulou M, Raftogiannis M, Renieris G, Orfanos SE, Kotanidou A, Sabracos L, Giamarellos-Bourboulis EJ.

Respirology. 2018 Oct;23(10):942-949. doi: 10.1111/resp.13320. Epub 2018 May 9.

PMID:
29741298
9.

Activated Protein C has No Effect on Pulmonary Capillary Endothelial Function in Septic Patients with Acute Respiratory Distress Syndrome: Association of Endothelial Dysfunction with Mortality.

Kaziani K, Vassiliou AG, Kotanidou A, Athanasiou C, Korovesi I, Glynos K, Orfanos SE.

Infect Dis Ther. 2018 Mar;7(Suppl 1):15-25. doi: 10.1007/s40121-018-0192-3. Epub 2018 Mar 16.

10.

Yeast Biofilm as a Bridge Between Medical and Environmental Microbiology Across Different Detection Techniques.

Roscini L, Vassiliou A, Corte L, Casagrande Pierantoni D, Robert V, Tascini C, Mattana S, Alunni Cardinali M, Orfanos SE, Fioretto D, Cardinali G.

Infect Dis Ther. 2018 Mar;7(Suppl 1):27-34. doi: 10.1007/s40121-018-0191-4. Epub 2018 Mar 16.

11.

The H3 Haplotype of the EPCR Gene Determines High sEPCR Levels in Critically Ill Septic Patients.

Vassiliou AG, Kotanidou A, Mastora Z, Tascini C, Cardinali G, Orfanos SE.

Infect Dis Ther. 2018 Mar;7(Suppl 1):3-14. doi: 10.1007/s40121-018-0193-2. Epub 2018 Mar 16.

12.

Pulmonary capillary recruitment in exercise and pulmonary hypertension.

Langleben D, Orfanos SE.

Eur Respir J. 2018 Mar 15;51(3). pii: 1702559. doi: 10.1183/13993003.02559-2017. Print 2018 Mar. No abstract available.

13.

Serum Admission 25-Hydroxyvitamin D Levels and Outcomes in Initially Non-Septic Critically Ill Patients.

Vassiliou AG, Jahaj E, Mastora Z, Stagaki E, Orfanos SE, Kotanidou A.

Shock. 2018 Nov;50(5):511-518. doi: 10.1097/SHK.0000000000001105.

PMID:
29337839
14.

Highly Selective Endothelin-1 Receptor A Inhibition Prevents Bleomycin-Induced Pulmonary Inflammation and Fibrosis in Mice.

Manitsopoulos N, Nikitopoulou I, Maniatis NA, Magkou C, Kotanidou A, Orfanos SE.

Respiration. 2018;95(2):122-136. doi: 10.1159/000481201. Epub 2017 Nov 9.

15.

Angiopoietin-2 Levels as Predictors of Outcome in Mechanically Ventilated Patients with Acute Respiratory Distress Syndrome.

Tsangaris I, Tsantes A, Vrigkou E, Kopterides P, Pelekanou A, Zerva K, Antonakos G, Konstantonis D, Mavrou I, Tsaknis G, Kyriazopoulou E, Mouktaroudi M, Kokori S, Orfanos SE, Giamarellos-Bourboulis EJ, Armaganidis A.

Dis Markers. 2017;2017:6758721. doi: 10.1155/2017/6758721. Epub 2017 Aug 29.

16.

Pulmonary Hypertension due to Lung Diseases and/or Hypoxia: What Do We Actually Know?

Kosanovic D, Herrera EA, Sydykov A, Orfanos SE, El Agha E.

Can Respir J. 2017;2017:9598089. doi: 10.1155/2017/9598089. Epub 2017 Aug 28. No abstract available.

17.

Macrophage activation-like syndrome: an immunological entity associated with rapid progression to death in sepsis.

Kyriazopoulou E, Leventogiannis K, Norrby-Teglund A, Dimopoulos G, Pantazi A, Orfanos SE, Rovina N, Tsangaris I, Gkavogianni T, Botsa E, Chassiou E, Kotanidou A, Kontouli C, Chaloulis P, Velissaris D, Savva A, Cullberg JS, Akinosoglou K, Gogos C, Armaganidis A, Giamarellos-Bourboulis EJ; Hellenic Sepsis Study Group.

BMC Med. 2017 Sep 18;15(1):172. doi: 10.1186/s12916-017-0930-5.

18.

Differential Expression of Aquaporins in Experimental Models of Acute Lung Injury.

Vassiliou AG, Manitsopoulos N, Kardara M, Maniatis NA, Orfanos SE, Kotanidou A.

In Vivo. 2017 Sep-Oct;31(5):885-894.

19.

Immunothrombosis in Acute Respiratory Distress Syndrome: Cross Talks between Inflammation and Coagulation.

Frantzeskaki F, Armaganidis A, Orfanos SE.

Respiration. 2017;93(3):212-225. doi: 10.1159/000453002. Epub 2016 Dec 21. Review.

20.

Validation of the new Sepsis-3 definitions: proposal for improvement in early risk identification.

Giamarellos-Bourboulis EJ, Tsaganos T, Tsangaris I, Lada M, Routsi C, Sinapidis D, Koupetori M, Bristianou M, Adamis G, Mandragos K, Dalekos GN, Kritselis I, Giannikopoulos G, Koutelidakis I, Pavlaki M, Antoniadou E, Vlachogiannis G, Koulouras V, Prekates A, Dimopoulos G, Koutsoukou A, Pnevmatikos I, Ioakeimidou A, Kotanidou A, Orfanos SE, Armaganidis A, Gogos C; Hellenic Sepsis Study Group.

Clin Microbiol Infect. 2017 Feb;23(2):104-109. doi: 10.1016/j.cmi.2016.11.003. Epub 2016 Nov 14.

21.

Vascular endothelial-cadherin downregulation as a feature of endothelial transdifferentiation in monocrotaline-induced pulmonary hypertension.

Nikitopoulou I, Orfanos SE, Kotanidou A, Maltabe V, Manitsopoulos N, Karras P, Kouklis P, Armaganidis A, Maniatis NA.

Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L352-63. doi: 10.1152/ajplung.00156.2014. Epub 2016 May 27.

22.

Exhaled nitric oxide and carbon monoxide in mechanically ventilated brain-injured patients.

Korovesi I, Kotanidou A, Papadomichelakis E, Livaditi O, Sotiropoulou C, Koutsoukou A, Marczin N, Orfanos SE.

J Breath Res. 2016 Mar 2;10(1):017107. doi: 10.1088/1752-7155/10/1/017107.

PMID:
26934167
23.

Respiratory mechanics in brain injury: A review.

Koutsoukou A, Katsiari M, Orfanos SE, Kotanidou A, Daganou M, Kyriakopoulou M, Koulouris NG, Rovina N.

World J Crit Care Med. 2016 Feb 4;5(1):65-73. doi: 10.5492/wjccm.v5.i1.65. eCollection 2016 Feb 4. Review.

24.

Biomarkers in infection and sepsis: Can they really indicate final outcome?

Tziolos N, Kotanidou A, Orfanos SE.

Int J Antimicrob Agents. 2015 Dec;46 Suppl 1:S29-32. doi: 10.1016/j.ijantimicag.2015.10.010. Epub 2015 Oct 31. Review.

PMID:
26607340
25.

Translational research in ARDS patients: new biological phenotypes.

Patry C, Orfanos SE, Rafat N.

Intensive Care Med. 2015 Nov;41(11):1986-9. doi: 10.1007/s00134-015-4005-9. Epub 2015 Jul 30. No abstract available.

PMID:
26224249
26.

Inhibition of HMGCoA reductase by simvastatin protects mice from injurious mechanical ventilation.

Manitsopoulos N, Orfanos SE, Kotanidou A, Nikitopoulou I, Siempos I, Magkou C, Dimopoulou I, Zakynthinos SG, Armaganidis A, Maniatis NA.

Respir Res. 2015 Feb 14;16:24. doi: 10.1186/s12931-015-0173-y.

27.

Does serum lactate combined with soluble endothelial selectins at ICU admission predict sepsis development?

Vassiliou AG, Mastora Z, Jahaj E, Koutsoukou A, Orfanos SE, Kotanidou A.

In Vivo. 2015 Mar-Apr;29(2):305-8.

PMID:
25792662
28.

Angiopoietin-2 associations with the underlying infection and sepsis severity.

Lymperopoulou K, Velissaris D, Kotsaki A, Antypa E, Georgiadou S, Tsaganos T, Koulenti D, Paggalou E, Damoraki G, Karagiannidis N, Orfanos SE.

Cytokine. 2015 May;73(1):163-8. doi: 10.1016/j.cyto.2015.01.022. Epub 2015 Mar 6.

PMID:
25748839
29.

Acute vasodilator responsiveness and microvascular recruitment in idiopathic pulmonary arterial hypertension.

Langleben D, Orfanos SE, Giovinazzo M, Schlesinger RD, Hirsch AM, Blenkhorn F, Lesenko L, Armaganidis A, Catravas JD.

Ann Intern Med. 2015 Jan 20;162(2):154-6. doi: 10.7326/M14-1402. No abstract available.

PMID:
25599356
30.

'Every breath you take I'll be watching you': measuring exercise kinetics during 6-min walking test in COPD.

Papaioannou AI, Orfanos SE.

Respiration. 2014;88(6):449-50. doi: 10.1159/000368372. Epub 2014 Oct 25. No abstract available.

31.

Elevated soluble endothelial protein C receptor levels at ICU admission are associated with sepsis development.

Vassiliou AG, Kotanidou A, Mastora Z, Maniatis NA, Albani P, Jahaj E, Koutsoukou A, Armaganidis A, Orfanos SE.

Minerva Anestesiol. 2015 Feb;81(2):125-34. Epub 2014 Sep 15.

32.

Longitudinal assessment of adrenal function in the early and prolonged phases of critical illness in septic patients: relations to cytokine levels and outcome.

Vassiliadi DA, Dimopoulou I, Tzanela M, Douka E, Livaditi O, Orfanos SE, Kotanidou A, Tsagarakis S.

J Clin Endocrinol Metab. 2014 Dec;99(12):4471-80. doi: 10.1210/jc.2014-2619.

PMID:
25148237
33.

Elevated biomarkers of endothelial dysfunction/activation at ICU admission are associated with sepsis development.

Vassiliou AG, Mastora Z, Orfanos SE, Jahaj E, Maniatis NA, Koutsoukou A, Armaganidis A, Kotanidou A.

Cytokine. 2014 Oct;69(2):240-7. doi: 10.1016/j.cyto.2014.06.010. Epub 2014 Jul 12.

PMID:
25016133
34.

Association of autophagy-related 16-like 1 (ATG16L1) gene polymorphism with sepsis severity in patients with sepsis and ventilator-associated pneumonia.

Savva A, Plantinga TS, Kotanidou A, Farcas M, Baziaka F, Raftogiannis M, Orfanos SE, Dimopoulos G, Netea MG, Giamarellos-Bourboulis EJ.

Eur J Clin Microbiol Infect Dis. 2014 Sep;33(9):1609-14. doi: 10.1007/s10096-014-2118-7. Epub 2014 May 3.

PMID:
24791954
35.

Pulmonary hypertension in β thalassaemia.

Anthi A, Orfanos SE, Armaganidis A.

Lancet Respir Med. 2013 Aug;1(6):488-96. doi: 10.1016/S2213-2600(13)70078-X. Epub 2013 Jun 12. Review.

PMID:
24429247
36.

Induced expression and functional effects of aquaporin-1 in human leukocytes in sepsis.

Vassiliou AG, Maniatis NA, Orfanos SE, Mastora Z, Jahaj E, Paparountas T, Armaganidis A, Roussos C, Aidinis V, Kotanidou A.

Crit Care. 2013 Sep 12;17(5):R199. doi: 10.1186/cc12893.

37.

Preclinical pulmonary capillary endothelial dysfunction is present in brain dead subjects.

Glynos C, Athanasiou C, Kotanidou A, Korovesi I, Kaziani K, Livaditi O, Dimopoulou I, Maniatis NA, Tsangaris I, Roussos C, Armaganidis A, Orfanos SE.

Pulm Circ. 2013 Apr;3(2):419-25. doi: 10.4103/2045-8932.113189.

38.

Endothelial protein C receptor polymorphisms and risk of severe sepsis in critically ill patients.

Vassiliou AG, Maniatis NA, Kotanidou A, Kallergi M, Karystinaki FS, Letsiou E, Glynos C, Kopterides P, Vassiliadi D, Nikitas N, Dimopoulou I, Armaganidis A, Orfanos SE.

Intensive Care Med. 2013 Oct;39(10):1752-9. doi: 10.1007/s00134-013-3018-5. Epub 2013 Jul 24.

PMID:
23881209
39.

Caveolar uptake and endothelial-protective effects of nanostructured lipid carriers in acid aspiration murine acute lung injury.

Kardara M, Hatziantoniou S, Sfika A, Vassiliou AG, Mourelatou E, Muagkou C, Armaganidis A, Roussos C, Orfanos SE, Kotanidou A, Maniatis NA.

Pharm Res. 2013 Jul;30(7):1836-47. doi: 10.1007/s11095-013-1027-2. Epub 2013 Apr 3.

PMID:
23549752
40.

Compartmentalization of lipid peroxidation in sepsis by multidrug-resistant gram-negative bacteria: experimental and clinical evidence.

Toufekoula C, Papadakis V, Tsaganos T, Routsi C, Orfanos SE, Kotanidou A, Carrer DP, Raftogiannis M, Baziaka F, Giamarellos-Bourboulis EJ.

Crit Care. 2013 Jan 16;17(1):R6. doi: 10.1186/cc11930.

41.

Pulmonary hypertension in parenchymal lung disease.

Tsangaris I, Tsaknis G, Anthi A, Orfanos SE.

Pulm Med. 2012;2012:684781. doi: 10.1155/2012/684781. Epub 2012 Oct 10.

42.

Interstitial cortisol obtained by microdialysis in mechanically ventilated septic patients: correlations with total and free serum cortisol.

Vassiliadi DA, Ilias I, Tzanela M, Nikitas N, Theodorakopoulou M, Kopterides P, Maniatis N, Diamantakis A, Orfanos SE, Perogamvros I, Armaganidis A, Keevil BG, Tsagarakis S, Dimopoulou I.

J Crit Care. 2013 Apr;28(2):158-65. doi: 10.1016/j.jcrc.2012.07.008. Epub 2012 Sep 13.

PMID:
22981531
43.

Treatment with bosentan in a patient with thalassemia intermedia and pulmonary arterial hypertension.

Anthi A, Tsangaris I, Hamodraka ES, Lekakis J, Armaganidis A, Orfanos SE.

Blood. 2012 Aug 16;120(7):1531-2. doi: 10.1182/blood-2012-04-422568. No abstract available.

PMID:
22899478
44.

Acid-induced acute lung injury in mice is associated with P44/42 and c-Jun N-terminal kinase activation and requires the function of tumor necrosis factor α receptor I.

Maniatis NA, Sfika A, Nikitopoulou I, Vassiliou AG, Magkou C, Armaganidis A, Roussos C, Kollias G, Orfanos SE, Kotanidou A.

Shock. 2012 Oct;38(4):381-6.

PMID:
22814289
45.

Red blood cell transfusion affects microdialysis-assessed interstitial lactate/pyruvate ratio in critically ill patients with late sepsis.

Kopterides P, Theodorakopoulou M, Nikitas N, Ilias I, Vassiliadi DA, Orfanos SE, Tsangaris I, Maniatis NA, Tsantes AE, Travlou A, Dimitriadis G, Armaganidis A, Ungerstedt U, Dimopoulou I.

Intensive Care Med. 2012 Nov;38(11):1843-50. doi: 10.1007/s00134-012-2635-8. Epub 2012 Jul 10.

PMID:
22777518
46.

Serial changes in adiponectin and resistin in critically ill patients with sepsis: associations with sepsis phase, severity, and circulating cytokine levels.

Vassiliadi DA, Tzanela M, Kotanidou A, Orfanos SE, Nikitas N, Armaganidis A, Koutsilieris M, Roussos C, Tsagarakis S, Dimopoulou I.

J Crit Care. 2012 Aug;27(4):400-9. doi: 10.1016/j.jcrc.2012.04.007. Epub 2012 Jun 12.

PMID:
22699030
47.

Genetic polymorphisms within tumor necrosis factor gene promoter region: a role for susceptibility to ventilator-associated pneumonia.

Kotsaki A, Raftogiannis M, Routsi C, Baziaka F, Kotanidou A, Antonopoulou A, Orfanos SE, Katsenos C, Koutoukas P, Plachouras D, Mandragos K, Giamarellos-Bourboulis EJ.

Cytokine. 2012 Aug;59(2):358-63. doi: 10.1016/j.cyto.2012.04.040. Epub 2012 May 18.

PMID:
22609212
48.

Effect of clarithromycin in inflammatory markers of patients with ventilator-associated pneumonia and sepsis caused by Gram-negative bacteria: results from a randomized clinical study.

Spyridaki A, Raftogiannis M, Antonopoulou A, Tsaganos T, Routsi C, Baziaka F, Karagianni V, Mouktaroudi M, Koutoukas P, Pelekanou A, Kotanidou A, Orfanos SE, van der Meer JW, Netea MG, Giamarellos-Bourboulis EJ.

Antimicrob Agents Chemother. 2012 Jul;56(7):3819-25. doi: 10.1128/AAC.05798-11. Epub 2012 May 7.

49.

Intercomparison of three recruitment maneuvers in acute respiratory distress syndrome: the role of Body Mass Index.

Katsiari M, Koulouris NG, Orfanos SE, Maguina N, Sotiropoulou C, Koutsoukou A.

Minerva Anestesiol. 2012 Jun;78(6):675-83. Epub 2012 Mar 8.

50.

TREM-1 expression on neutrophils and monocytes of septic patients: relation to the underlying infection and the implicated pathogen.

Poukoulidou T, Spyridaki A, Mihailidou I, Kopterides P, Pistiki A, Alexiou Z, Chrisofos M, Dimopoulou I, Drimoussis P, Giamarellos-Bourboulis EJ, Koutelidakis I, Marioli A, Mega A, Orfanos SE, Theodorakopoulou M, Tsironis C, Maggina N, Polychronopoulos V, Tsangaris I; Hellenic Sepsis Study Group.

BMC Infect Dis. 2011 Nov 4;11:309. doi: 10.1186/1471-2334-11-309.

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