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Epidemiology and initial management of pulmonary arterial hypertension: real-world data from the Hellenic pulmOnary hyPertension rEgistry (HOPE).

Arvanitaki A, Boutsikou M, Anthi A, Apostolopoulou S, Avgeropoulou A, Demerouti E, Farmakis D, Feloukidis C, Giannakoulas G, Karvounis H, Karyofyllis P, Mitrouska I, Mouratoglou S, Naka KK, Orfanos SE, Panagiotidou E, Pitsiou G, Rammos S, Stagaki E, Stanopoulos I, Thomaidi A, Triantafyllidi H, Tsangaris I, Tsiapras D, Voudris V, Manginas A; Hellenic Society for the Study of Pulmonary Hypertension (HSSPH).

Pulm Circ. 2019 Oct 14;9(3):2045894019877157. doi: 10.1177/2045894019877157. eCollection 2019 Jul-Sep.


Pulmonary capillary surface area in supine exercising humans: demonstration of vascular recruitment.

Langleben D, Orfanos SE, Giovinazzo M, Schlesinger RD, Naeije R, Fox BD, Abualsaud AO, Blenkhorn F, Rudski LG, Catravas JD.

Am J Physiol Lung Cell Mol Physiol. 2019 Sep 1;317(3):L361-L368. doi: 10.1152/ajplung.00098.2019. Epub 2019 Jun 26.


Decreased glucocorticoid receptor expression during critical illness.

Vassiliou AG, Floros G, Jahaj E, Stamogiannos G, Gennimata S, Vassiliadi DA, Tsagarakis S, Tzanela M, Ilias I, Orfanos SE, Kotanidou A, Dimopoulou I.

Eur J Clin Invest. 2019 Apr;49(4):e13073. doi: 10.1111/eci.13073. Epub 2019 Feb 18.


Why do psychiatric patients attend or not attend treatment groups in the community: A qualitative study.

Dilgul M, McNamee P, Orfanos S, Carr CE, Priebe S.

PLoS One. 2018 Dec 13;13(12):e0208448. doi: 10.1371/journal.pone.0208448. eCollection 2018.


A case of disseminated tuberculosis mimicking metastatic cancer.

Chamberlin K, Orfanos S, Mukherjee A, Moy E, Koganti M, Khan W.

Respir Med Case Rep. 2018 Oct 2;25:239-241. doi: 10.1016/j.rmcr.2018.10.001. eCollection 2018.


Obesity increases airway smooth muscle responses to contractile agonists.

Orfanos S, Jude J, Deeney BT, Cao G, Rastogi D, van Zee M, Pushkarsky I, Munoz HE, Damoiseaux R, Di Carlo D, Panettieri RA Jr.

Am J Physiol Lung Cell Mol Physiol. 2018 Nov 1;315(5):L673-L681. doi: 10.1152/ajplung.00459.2017. Epub 2018 Aug 30.


Impact of gram negative bacteria airway recolonization on the occurrence of chronic lung allograft dysfunction after lung transplantation in a population of cystic fibrosis patients.

Orfanos S, Gomez C, Baron S, Akkisetty R, Dufeu N, Coltey B, Thomas PA, Rolain JM, Reynaud-Gaubert M.

BMC Microbiol. 2018 Aug 20;18(1):88. doi: 10.1186/s12866-018-1231-7.


Platelet and coagulation disorders in newly diagnosed patients with pulmonary arterial hypertension.

Vrigkou E, Tsangaris I, Bonovas S, Kopterides P, Kyriakou E, Konstantonis D, Pappas A, Anthi A, Gialeraki A, Orfanos SE, Armaganidis A, Tsantes A.

Platelets. 2019;30(5):646-651. doi: 10.1080/09537104.2018.1499890. Epub 2018 Jul 26.


Treating nosocomial pneumonia: what's new.

Frantzeskaki F, Orfanos SE.

ERJ Open Res. 2018 Jun 26;4(2). pii: 00058-2018. doi: 10.1183/23120541.00058-2018. eCollection 2018 Apr.


Early increase of VEGF-A is associated with resolution of ventilator-associated pneumonia: Clinical and experimental evidence.

Strouvalis I, Routsi C, Adamopoulou M, Raftogiannis M, Renieris G, Orfanos SE, Kotanidou A, Sabracos L, Giamarellos-Bourboulis EJ.

Respirology. 2018 Oct;23(10):942-949. doi: 10.1111/resp.13320. Epub 2018 May 9.


Activated Protein C has No Effect on Pulmonary Capillary Endothelial Function in Septic Patients with Acute Respiratory Distress Syndrome: Association of Endothelial Dysfunction with Mortality.

Kaziani K, Vassiliou AG, Kotanidou A, Athanasiou C, Korovesi I, Glynos K, Orfanos SE.

Infect Dis Ther. 2018 Mar;7(Suppl 1):15-25. doi: 10.1007/s40121-018-0192-3. Epub 2018 Mar 16.


Yeast Biofilm as a Bridge Between Medical and Environmental Microbiology Across Different Detection Techniques.

Roscini L, Vassiliou A, Corte L, Casagrande Pierantoni D, Robert V, Tascini C, Mattana S, Alunni Cardinali M, Orfanos SE, Fioretto D, Cardinali G.

Infect Dis Ther. 2018 Mar;7(Suppl 1):27-34. doi: 10.1007/s40121-018-0191-4. Epub 2018 Mar 16.


The H3 Haplotype of the EPCR Gene Determines High sEPCR Levels in Critically Ill Septic Patients.

Vassiliou AG, Kotanidou A, Mastora Z, Tascini C, Cardinali G, Orfanos SE.

Infect Dis Ther. 2018 Mar;7(Suppl 1):3-14. doi: 10.1007/s40121-018-0193-2. Epub 2018 Mar 16.


Pulmonary capillary recruitment in exercise and pulmonary hypertension.

Langleben D, Orfanos SE.

Eur Respir J. 2018 Mar 15;51(3). pii: 1702559. doi: 10.1183/13993003.02559-2017. Print 2018 Mar. No abstract available.


Serum Admission 25-Hydroxyvitamin D Levels and Outcomes in Initially Non-Septic Critically Ill Patients.

Vassiliou AG, Jahaj E, Mastora Z, Stagaki E, Orfanos SE, Kotanidou A.

Shock. 2018 Nov;50(5):511-518. doi: 10.1097/SHK.0000000000001105.


Highly Selective Endothelin-1 Receptor A Inhibition Prevents Bleomycin-Induced Pulmonary Inflammation and Fibrosis in Mice.

Manitsopoulos N, Nikitopoulou I, Maniatis NA, Magkou C, Kotanidou A, Orfanos SE.

Respiration. 2018;95(2):122-136. doi: 10.1159/000481201. Epub 2017 Nov 9.


Investigating the impact of overnight fasting on intrinsic functional connectivity: a double-blind fMRI study.

Orfanos S, Toygar T, Berthold-Losleben M, Chechko N, Durst A, Laoutidis ZG, Vocke S, Weidenfeld C, Schneider F, Karges W, Beckmann CF, Habel U, Kohn N.

Brain Imaging Behav. 2018 Aug;12(4):1150-1159. doi: 10.1007/s11682-017-9777-9.


Angiopoietin-2 Levels as Predictors of Outcome in Mechanically Ventilated Patients with Acute Respiratory Distress Syndrome.

Tsangaris I, Tsantes A, Vrigkou E, Kopterides P, Pelekanou A, Zerva K, Antonakos G, Konstantonis D, Mavrou I, Tsaknis G, Kyriazopoulou E, Mouktaroudi M, Kokori S, Orfanos SE, Giamarellos-Bourboulis EJ, Armaganidis A.

Dis Markers. 2017;2017:6758721. doi: 10.1155/2017/6758721. Epub 2017 Aug 29.


Pulmonary Hypertension due to Lung Diseases and/or Hypoxia: What Do We Actually Know?

Kosanovic D, Herrera EA, Sydykov A, Orfanos SE, El Agha E.

Can Respir J. 2017;2017:9598089. doi: 10.1155/2017/9598089. Epub 2017 Aug 28. No abstract available.


Macrophage activation-like syndrome: an immunological entity associated with rapid progression to death in sepsis.

Kyriazopoulou E, Leventogiannis K, Norrby-Teglund A, Dimopoulos G, Pantazi A, Orfanos SE, Rovina N, Tsangaris I, Gkavogianni T, Botsa E, Chassiou E, Kotanidou A, Kontouli C, Chaloulis P, Velissaris D, Savva A, Cullberg JS, Akinosoglou K, Gogos C, Armaganidis A, Giamarellos-Bourboulis EJ; Hellenic Sepsis Study Group.

BMC Med. 2017 Sep 18;15(1):172. doi: 10.1186/s12916-017-0930-5.


Differential Expression of Aquaporins in Experimental Models of Acute Lung Injury.

Vassiliou AG, Manitsopoulos N, Kardara M, Maniatis NA, Orfanos SE, Kotanidou A.

In Vivo. 2017 Sep-Oct;31(5):885-894.


Vasodilator responsiveness in idiopathic pulmonary arterial hypertension: identifying a distinct phenotype with distinct physiology and distinct prognosis.

Langleben D, Orfanos S.

Pulm Circ. 2017 Jul-Sep;7(3):588-597. doi: 10.1177/2045893217714231. Epub 2017 Jun 20.


Incidence and Risk Factors for Organ/Space Infection after Radiofrequency-Assisted Hepatectomy or Ablation of Liver Tumors in a Single Center: More than Meets the Eye.

Karavokyros I, Orfanos S, Angelou A, Meropouli A, Schizas D, Griniatsos J, Pikoulis E.

Front Surg. 2017 Apr 7;4:17. doi: 10.3389/fsurg.2017.00017. eCollection 2017.


Switch of noninvasive ventilation (NIV) to continuous positive airway pressure (CPAP) in patients with obesity hypoventilation syndrome: a pilot study.

Orfanos S, Jaffuel D, Perrin C, Molinari N, Chanez P, Palot A.

BMC Pulm Med. 2017 Mar 14;17(1):50. doi: 10.1186/s12890-017-0391-9.


Using video-annotation software to identify interactions in group therapies for schizophrenia: assessing reliability and associations with outcomes.

Orfanos S, Akther SF, Abdul-Basit M, McCabe R, Priebe S.

BMC Psychiatry. 2017 Feb 10;17(1):65. doi: 10.1186/s12888-017-1217-2.


Immunothrombosis in Acute Respiratory Distress Syndrome: Cross Talks between Inflammation and Coagulation.

Frantzeskaki F, Armaganidis A, Orfanos SE.

Respiration. 2017;93(3):212-225. doi: 10.1159/000453002. Epub 2016 Dec 21. Review.


The impact of gender on treatment effectiveness of body psychotherapy for negative symptoms of schizophrenia: A secondary analysis of the NESS trial data.

Savill M, Orfanos S, Bentall R, Reininghaus U, Wykes T, Priebe S.

Psychiatry Res. 2017 Jan;247:73-78. doi: 10.1016/j.psychres.2016.11.020. Epub 2016 Nov 14.


[Health care providers' knowledge and abilities to use inhalation devices and spacers].

Orfanos S, Carsin A, Baravalle M, Dubus JC.

Rev Mal Respir. 2017 May;34(5):561-570. doi: 10.1016/j.rmr.2016.08.005. Epub 2016 Nov 15. French.


Validation of the new Sepsis-3 definitions: proposal for improvement in early risk identification.

Giamarellos-Bourboulis EJ, Tsaganos T, Tsangaris I, Lada M, Routsi C, Sinapidis D, Koupetori M, Bristianou M, Adamis G, Mandragos K, Dalekos GN, Kritselis I, Giannikopoulos G, Koutelidakis I, Pavlaki M, Antoniadou E, Vlachogiannis G, Koulouras V, Prekates A, Dimopoulos G, Koutsoukou A, Pnevmatikos I, Ioakeimidou A, Kotanidou A, Orfanos SE, Armaganidis A, Gogos C; Hellenic Sepsis Study Group.

Clin Microbiol Infect. 2017 Feb;23(2):104-109. doi: 10.1016/j.cmi.2016.11.003. Epub 2016 Nov 14.


Never underestimate a dermal lesion: reflections on a rare tumor.

Vailas MG, Moris D, Orfanos S, Vergadis C, Pikoulis E.

Minerva Chir. 2016 Oct;71(5):349-51. No abstract available.


The time difference between clinical improvement and exercise tolerance increase following pulmonary thromboendarterectomy.

Triantafyllidi H, Katogiannis K, Mayer E, Anthi A, Orfanos S, Lekakis J.

Int J Cardiol. 2016 Nov 1;222:267-269. doi: 10.1016/j.ijcard.2016.07.244. Epub 2016 Jul 30. No abstract available.


The relationship between experiential deficits of negative symptoms and subjective quality of life in schizophrenia.

Savill M, Orfanos S, Reininghaus U, Wykes T, Bentall R, Priebe S.

Schizophr Res. 2016 Oct;176(2-3):387-391. doi: 10.1016/j.schres.2016.06.017. Epub 2016 Jun 18.


Vascular endothelial-cadherin downregulation as a feature of endothelial transdifferentiation in monocrotaline-induced pulmonary hypertension.

Nikitopoulou I, Orfanos SE, Kotanidou A, Maltabe V, Manitsopoulos N, Karras P, Kouklis P, Armaganidis A, Maniatis NA.

Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L352-63. doi: 10.1152/ajplung.00156.2014. Epub 2016 May 27.


Exhaled nitric oxide and carbon monoxide in mechanically ventilated brain-injured patients.

Korovesi I, Kotanidou A, Papadomichelakis E, Livaditi O, Sotiropoulou C, Koutsoukou A, Marczin N, Orfanos SE.

J Breath Res. 2016 Mar 2;10(1):017107. doi: 10.1088/1752-7155/10/1/017107.


Respiratory mechanics in brain injury: A review.

Koutsoukou A, Katsiari M, Orfanos SE, Kotanidou A, Daganou M, Kyriakopoulou M, Koulouris NG, Rovina N.

World J Crit Care Med. 2016 Feb 4;5(1):65-73. doi: 10.5492/wjccm.v5.i1.65. eCollection 2016 Feb 4. Review.


Single-Incision Laparoscopic Right Hemi-Colectomy: a Systematic Review.

Apostolou KG, Orfanos SV, Papalois AE, Felekouras ES, Zografos GC, Liakakos T.

Indian J Surg. 2015 Aug;77(4):301-12. doi: 10.1007/s12262-015-1282-z. Epub 2015 Jun 10. Review.


Biomarkers in infection and sepsis: Can they really indicate final outcome?

Tziolos N, Kotanidou A, Orfanos SE.

Int J Antimicrob Agents. 2015 Dec;46 Suppl 1:S29-32. doi: 10.1016/j.ijantimicag.2015.10.010. Epub 2015 Oct 31. Review.


Cardiovascular risk in pulmonary alveolar proteinosis.

Manali ED, Papadaki G, Konstantonis D, Tsangaris I, Papaioannou AI, Kolilekas L, Schams A, Kagouridis K, Karakatsani A, Orfanos S, Griese M, Papiris SA.

Expert Rev Respir Med. 2016 Feb;10(2):235-40. doi: 10.1586/17476348.2016.1116389. Epub 2015 Nov 27.


Seatbelt sign in a case of blunt abdominal trauma; what lies beneath it?

Vailas MG, Moris D, Orfanos S, Vergadis C, Papalampros A.

BMC Surg. 2015 Oct 30;15:121. doi: 10.1186/s12893-015-0108-z.


Translational research in ARDS patients: new biological phenotypes.

Patry C, Orfanos SE, Rafat N.

Intensive Care Med. 2015 Nov;41(11):1986-9. doi: 10.1007/s00134-015-4005-9. Epub 2015 Jul 30. No abstract available.


Are Group Psychotherapeutic Treatments Effective for Patients with Schizophrenia? A Systematic Review and Meta-Analysis.

Orfanos S, Banks C, Priebe S.

Psychother Psychosom. 2015;84(4):241-9. doi: 10.1159/000377705. Epub 2015 May 23. Review.


Inhibition of HMGCoA reductase by simvastatin protects mice from injurious mechanical ventilation.

Manitsopoulos N, Orfanos SE, Kotanidou A, Nikitopoulou I, Siempos I, Magkou C, Dimopoulou I, Zakynthinos SG, Armaganidis A, Maniatis NA.

Respir Res. 2015 Feb 14;16:24. doi: 10.1186/s12931-015-0173-y.


In a sweet mood? Effects of experimental modulation of blood glucose levels on mood-induction during fMRI.

Kohn N, Toygar T, Weidenfeld C, Berthold-Losleben M, Chechko N, Orfanos S, Vocke S, Durst A, Laoutidis ZG, Karges W, Schneider F, Habel U.

Neuroimage. 2015 Jun;113:246-56. doi: 10.1016/j.neuroimage.2015.03.024. Epub 2015 Mar 18.


Does serum lactate combined with soluble endothelial selectins at ICU admission predict sepsis development?

Vassiliou AG, Mastora Z, Jahaj E, Koutsoukou A, Orfanos SE, Kotanidou A.

In Vivo. 2015 Mar-Apr;29(2):305-8.


Angiopoietin-2 associations with the underlying infection and sepsis severity.

Lymperopoulou K, Velissaris D, Kotsaki A, Antypa E, Georgiadou S, Tsaganos T, Koulenti D, Paggalou E, Damoraki G, Karagiannidis N, Orfanos SE.

Cytokine. 2015 May;73(1):163-8. doi: 10.1016/j.cyto.2015.01.022. Epub 2015 Mar 6.


Primary retroperitoneal mucinous cystadenoma. A rare case with two cysts and review of the literature.

Paraskevakou H, Orfanos S, Diamantis T, Konstantinidou A, Patsouris E.

Hippokratia. 2014 Jul-Sep;18(3):278-81.


Acute vasodilator responsiveness and microvascular recruitment in idiopathic pulmonary arterial hypertension.

Langleben D, Orfanos SE, Giovinazzo M, Schlesinger RD, Hirsch AM, Blenkhorn F, Lesenko L, Armaganidis A, Catravas JD.

Ann Intern Med. 2015 Jan 20;162(2):154-6. doi: 10.7326/M14-1402. No abstract available.


Effects of overnight fasting on working memory-related brain network: an fMRI study.

Chechko N, Vocke S, Habel U, Toygar T, Kuckartz L, Berthold-Losleben M, Laoutidis ZG, Orfanos S, Wassenberg A, Karges W, Schneider F, Kohn N.

Hum Brain Mapp. 2015 Mar;36(3):839-51. doi: 10.1002/hbm.22668. Epub 2014 Nov 12.


'Every breath you take I'll be watching you': measuring exercise kinetics during 6-min walking test in COPD.

Papaioannou AI, Orfanos SE.

Respiration. 2014;88(6):449-50. doi: 10.1159/000368372. Epub 2014 Oct 25. No abstract available.


Impact of 3 Common ABCA1 Gene Polymorphisms on Optimal vs Non-Optimal Lipid Profile in Greek Young Nurses.

Marvaki A, Kolovou V, Katsiki N, Boutsikou M, Kotanidou A, Orfanos S, Filippatos G, Marvaki K, Koumoulidis A, Mavrogeni S, Kolovou G.

Open Cardiovasc Med J. 2014 Sep 25;8:83-7. doi: 10.2174/1874192401408010083. eCollection 2014.

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