Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 97

1.

Single Nucleotide Polymorphisms at a Distance from Aryl Hydrocarbon Receptor (AHR) Binding Sites Influence AHR Ligand-Dependent Gene Expression.

Neavin DR, Lee JH, Liu D, Ye Z, Li H, Wang L, Ordog T, Weinshilboum RM.

Drug Metab Dispos. 2019 Sep;47(9):983-994. doi: 10.1124/dmd.119.087312. Epub 2019 Jul 10.

PMID:
31292129
2.

Recurrent MSC E116K mutations in ALK-negative anaplastic large cell lymphoma.

Luchtel RA, Zimmermann MT, Hu G, Dasari S, Jiang M, Oishi N, Jacobs HK, Zeng Y, Hundal T, Rech KL, Ketterling RP, Lee JH, Eckloff BW, Yan H, Gaonkar KS, Tian S, Ye Z, Kadin ME, Sidhu J, Jiang L, Voss J, Link BK, Syrbu SI, Facchetti F, Bennani NN, Slager SL, Ordog T, Kocher JP, Cerhan JR, Ansell SM, Feldman AL.

Blood. 2019 Jun 27;133(26):2776-2789. doi: 10.1182/blood.2019000626. Epub 2019 May 17.

PMID:
31101622
3.

Enhanced and controlled chromatin extraction from FFPE tissues and the application to ChIP-seq.

Zhong J, Ye Z, Clark CR, Lenz SW, Nguyen JH, Yan H, Robertson KD, Farrugia G, Zhang Z, Ordog T, Lee JH.

BMC Genomics. 2019 Mar 29;20(1):249. doi: 10.1186/s12864-019-5639-8.

4.

Genomic aberrations in cell cycle genes predict progression of KIT-mutant gastrointestinal stromal tumors (GISTs).

Heinrich MC, Patterson J, Beadling C, Wang Y, Debiec-Rychter M, Dewaele B, Corless CL, Duensing A, Raut CP, Rubin B, Ordog T, van de Rijn M, Call J, Mühlenberg T, Fletcher JA, Bauer S.

Clin Sarcoma Res. 2019 Mar 5;9:3. doi: 10.1186/s13569-019-0112-7. eCollection 2019.

5.

Direct repression of anoctamin 1 (ANO1) gene transcription by Gli proteins.

Mazzone A, Gibbons SJ, Eisenman ST, Strege PR, Zheng T, D'Amato M, Ordog T, Fernandez-Zapico ME, Farrugia G.

FASEB J. 2019 May;33(5):6632-6642. doi: 10.1096/fj.201802373R. Epub 2019 Feb 25.

PMID:
30802137
6.

Muscularis Propria Macrophages Alter the Proportion of Nitrergic but Not Cholinergic Gastric Myenteric Neurons.

Cipriani G, Terhaar ML, Eisenman ST, Ji S, Linden DR, Wright AM, Sha L, Ordog T, Szurszewski JH, Gibbons SJ, Farrugia G.

Cell Mol Gastroenterol Hepatol. 2019;7(3):689-691.e4. doi: 10.1016/j.jcmgh.2019.01.005. Epub 2019 Jan 31. No abstract available.

7.

HDAC3 restrains CD8-lineage genes to maintain a bi-potential state in CD4+CD8+ thymocytes for CD4-lineage commitment.

Philips RL, Lee JH, Gaonkar K, Chanana P, Chung JY, Romero Arocha SR, Schwab A, Ordog T, Shapiro VS.

Elife. 2019 Jan 18;8. pii: e43821. doi: 10.7554/eLife.43821.

8.

Association Between Renal Cell Carcinoma and Myelodysplastic Syndromes: Epigenetic Underpinning?

Shenoy N, Mudireddy M, Vallapureddy R, Leung N, Pagliaro L, Witzig T, Ou FS, Ordog T, Cheville J, Patnaik M, Thompson RH, Tefferi A, Begna K.

Clin Genitourin Cancer. 2018 Dec;16(6):e1117-e1122. doi: 10.1016/j.clgc.2018.06.008. Epub 2018 Jun 28.

PMID:
30077464
9.

Epigenetics of gastrointestinal diseases: notes from a workshop.

Marks DL, Olson RL, Urrutia R, Billadeau DD, Roy N, Calin GA, Fabbri M, Koutsioumpa M, Iliopoulos D, Ordog T, Huebert R, Sarmento O, Bamidele AO, Faubion W, Lomberk GL, Siveke J, Ahuja N, Iovanna J, Hlady RA, Robertson K, Kisiel J, Pin CL, Fernandez-Zapico ME.

Epigenetics. 2018;13(4):449-457. doi: 10.1080/15592294.2018.1464351. Epub 2018 Jul 30.

10.

A droplet microfluidic platform for efficient enzymatic chromatin digestion enables robust determination of nucleosome positioning.

Xu Y, Lee JH, Li Z, Wang L, Ordog T, Bailey RC.

Lab Chip. 2018 Aug 21;18(17):2583-2592. doi: 10.1039/c8lc00599k.

PMID:
30046796
11.

Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes.

Lomberk G, Blum Y, Nicolle R, Nair A, Gaonkar KS, Marisa L, Mathison A, Sun Z, Yan H, Elarouci N, Armenoult L, Ayadi M, Ordog T, Lee JH, Oliver G, Klee E, Moutardier V, Gayet O, Bian B, Duconseil P, Gilabert M, Bigonnet M, Garcia S, Turrini O, Delpero JR, Giovannini M, Grandval P, Gasmi M, Secq V, De Reyniès A, Dusetti N, Iovanna J, Urrutia R.

Nat Commun. 2018 May 17;9(1):1978. doi: 10.1038/s41467-018-04383-6.

12.

High temporal resolution gastric emptying breath tests in mice.

Miller KE, Bajzer Ž, Hein SS, Phillips JE, Syed S, Wright AM, Cipriani G, Gibbons SJ, Szurszewski JH, Farrugia G, Ordog T, Linden DR.

Neurogastroenterol Motil. 2018 Mar 25:e13333. doi: 10.1111/nmo.13333. [Epub ahead of print]

PMID:
29575442
13.

Change in Populations of Macrophages Promotes Development of Delayed Gastric Emptying in Mice.

Cipriani G, Gibbons SJ, Miller KE, Yang DS, Terhaar ML, Eisenman ST, Ördög T, Linden DR, Gajdos GB, Szurszewski JH, Farrugia G.

Gastroenterology. 2018 Jun;154(8):2122-2136.e12. doi: 10.1053/j.gastro.2018.02.027. Epub 2018 Mar 6.

14.

CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity.

Karakashev S, Zhu H, Wu S, Yokoyama Y, Bitler BG, Park PH, Lee JH, Kossenkov AV, Gaonkar KS, Yan H, Drapkin R, Conejo-Garcia JR, Speicher DW, Ordog T, Zhang R.

Nat Commun. 2018 Feb 12;9(1):631. doi: 10.1038/s41467-018-03031-3.

15.

Purification of nanogram-range immunoprecipitated DNA in ChIP-seq application.

Zhong J, Ye Z, Lenz SW, Clark CR, Bharucha A, Farrugia G, Robertson KD, Zhang Z, Ordog T, Lee JH.

BMC Genomics. 2017 Dec 21;18(1):985. doi: 10.1186/s12864-017-4371-5.

16.

Conserved DNA methylation combined with differential frontal cortex and cerebellar expression distinguishes C9orf72-associated and sporadic ALS, and implicates SERPINA1 in disease.

Ebbert MTW, Ross CA, Pregent LJ, Lank RJ, Zhang C, Katzman RB, Jansen-West K, Song Y, da Rocha EL, Palmucci C, Desaro P, Robertson AE, Caputo AM, Dickson DW, Boylan KB, Rademakers R, Ordog T, Li H, Belzil VV.

Acta Neuropathol. 2017 Nov;134(5):715-728. doi: 10.1007/s00401-017-1760-4. Epub 2017 Aug 14.

17.

Hyperglycemia Increases Interstitial Cells of Cajal via MAPK1 and MAPK3 Signaling to ETV1 and KIT, Leading to Rapid Gastric Emptying.

Hayashi Y, Toyomasu Y, Saravanaperumal SA, Bardsley MR, Smestad JA, Lorincz A, Eisenman ST, Cipriani G, Nelson Holte MH, Al Khazal FJ, Syed SA, Gajdos GB, Choi KM, Stoltz GJ, Miller KE, Kendrick ML, Rubin BP, Gibbons SJ, Bharucha AE, Linden DR, Maher LJ 3rd, Farrugia G, Ordog T.

Gastroenterology. 2017 Aug;153(2):521-535.e20. doi: 10.1053/j.gastro.2017.04.020. Epub 2017 Apr 21.

18.

Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix.

Heim JB, Squirewell EJ, Neu A, Zocher G, Sominidi-Damodaran S, Wyles SP, Nikolova E, Behrendt N, Saunte DM, Lock-Andersen J, Gaonkar KS, Yan H, Sarkaria JN, Krendel M, van Deursen J, Sprangers R, Stehle T, Böttcher RT, Lee JH, Ordog T, Meves A.

Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3933-3938. doi: 10.1073/pnas.1614894114. Epub 2017 Mar 27.

19.

RPA Interacts with HIRA and Regulates H3.3 Deposition at Gene Regulatory Elements in Mammalian Cells.

Zhang H, Gan H, Wang Z, Lee JH, Zhou H, Ordog T, Wold MS, Ljungman M, Zhang Z.

Mol Cell. 2017 Jan 19;65(2):272-284. doi: 10.1016/j.molcel.2016.11.030.

20.

Conditional genetic deletion of Ano1 in interstitial cells of Cajal impairs Ca2+ transients and slow waves in adult mouse small intestine.

Malysz J, Gibbons SJ, Saravanaperumal SA, Du P, Eisenman ST, Cao C, Oh U, Saur D, Klein S, Ordog T, Farrugia G.

Am J Physiol Gastrointest Liver Physiol. 2017 Mar 1;312(3):G228-G245. doi: 10.1152/ajpgi.00363.2016. Epub 2016 Dec 15.

21.

BET Inhibitors Suppress ALDH Activity by Targeting ALDH1A1 Super-Enhancer in Ovarian Cancer.

Yokoyama Y, Zhu H, Lee JH, Kossenkov AV, Wu SY, Wickramasinghe JM, Yin X, Palozola KC, Gardini A, Showe LC, Zaret KS, Liu Q, Speicher D, Conejo-Garcia JR, Bradner JE, Zhang Z, Sood AK, Ordog T, Bitler BG, Zhang R.

Cancer Res. 2016 Nov 1;76(21):6320-6330.

22.

Interleukin 10 Restores Gastric Emptying, Electrical Activity, and Interstitial Cells of Cajal Networks in Diabetic Mice.

Choi KM, Gibbons SJ, Sha L, Beyder A, Verhulst PJ, Cipriani G, Phillips JE, Bauer AJ, Ordog T, Camp JJ, Ge X, Bharucha AE, Linden DR, Szurszewski JH, Kashyap PC, Farrugia G.

Cell Mol Gastroenterol Hepatol. 2016 Apr 23;2(4):454-467. eCollection 2016 Jul.

23.

Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression.

Tang CM, Lee TE, Syed SA, Burgoyne AM, Leonard SY, Gao F, Chan JC, Shi E, Chmielecki J, Morosini D, Wang K, Ross JS, Kendrick ML, Bardsley MR, Siena M, Mao J, Harismendy O, Ordog T, Sicklick JK.

Oncotarget. 2016 Nov 29;7(48):78226-78241. doi: 10.18632/oncotarget.12909.

24.

Altered gut microbiota in female mice with persistent low body weights following removal of post-weaning chronic dietary restriction.

Chen J, Toyomasu Y, Hayashi Y, Linden DR, Szurszewski JH, Nelson H, Farrugia G, Kashyap PC, Chia N, Ordog T.

Genome Med. 2016 Oct 3;8(1):103.

25.

The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas.

Fang D, Gan H, Lee JH, Han J, Wang Z, Riester SM, Jin L, Chen J, Zhou H, Wang J, Zhang H, Yang N, Bradley EW, Ho TH, Rubin BP, Bridge JA, Thibodeau SN, Ordog T, Chen Y, van Wijnen AJ, Oliveira AM, Xu RM, Westendorf JJ, Zhang Z.

Science. 2016 Jun 10;352(6291):1344-8. doi: 10.1126/science.aae0065. Epub 2016 May 26.

26.

Gene expression, methylation and neuropathology correlations at progressive supranuclear palsy risk loci.

Allen M, Burgess JD, Ballard T, Serie D, Wang X, Younkin CS, Sun Z, Kouri N, Baheti S, Wang C, Carrasquillo MM, Nguyen T, Lincoln S, Malphrus K, Murray M, Golde TE, Price ND, Younkin SG, Schellenberg GD, Asmann Y, Ordog T, Crook J, Dickson D, Ertekin-Taner N.

Acta Neuropathol. 2016 Aug;132(2):197-211. doi: 10.1007/s00401-016-1576-7. Epub 2016 Apr 26.

27.

USP51 deubiquitylates H2AK13,15ub and regulates DNA damage response.

Wang Z, Zhang H, Liu J, Cheruiyot A, Lee JH, Ordog T, Lou Z, You Z, Zhang Z.

Genes Dev. 2016 Apr 15;30(8):946-59. doi: 10.1101/gad.271841.115.

28.

Diabetic Csf1op/op mice lacking macrophages are protected against the development of delayed gastric emptying.

Cipriani G, Gibbons SJ, Verhulst PJ, Choi KM, Eisenman ST, Hein SS, Ordog T, Linden DR, Szurszewski JH, Farrugia G.

Cell Mol Gastroenterol Hepatol. 2016 Jan 1;2(1):40-47.

29.

Genome-Wide Epigenetic Studies in Human Disease: A Primer on -Omic Technologies.

Yan H, Tian S, Slager SL, Sun Z, Ordog T.

Am J Epidemiol. 2016 Jan 15;183(2):96-109. doi: 10.1093/aje/kwv187. Epub 2015 Dec 30.

30.

The common point for forensic and anthropologic genetics and individualized medicine.

Kayser M, Ordog T.

Croat Med J. 2015 Jun;56(3):177-8. No abstract available.

31.

Targeting Disease Persistence in Gastrointestinal Stromal Tumors.

Ordog T, Zörnig M, Hayashi Y.

Stem Cells Transl Med. 2015 Jul;4(7):702-7. doi: 10.5966/sctm.2014-0298. Epub 2015 May 1.

32.

Platelet-Derived Growth Factor Receptor-α Regulates Proliferation of Gastrointestinal Stromal Tumor Cells With Mutations in KIT by Stabilizing ETV1.

Hayashi Y, Bardsley MR, Toyomasu Y, Milosavljevic S, Gajdos GB, Choi KM, Reid-Lombardo KM, Kendrick ML, Bingener-Casey J, Tang CM, Sicklick JK, Gibbons SJ, Farrugia G, Taguchi T, Gupta A, Rubin BP, Fletcher JA, Ramachandran A, Ordog T.

Gastroenterology. 2015 Aug;149(2):420-32.e16. doi: 10.1053/j.gastro.2015.04.006. Epub 2015 Apr 9.

33.

FAM96A is a novel pro-apoptotic tumor suppressor in gastrointestinal stromal tumors.

Schwamb B, Pick R, Fernández SB, Völp K, Heering J, Dötsch V, Bösser S, Jung J, Beinoraviciute-Kellner R, Wesely J, Zörnig I, Hammerschmidt M, Nowak M, Penzel R, Zatloukal K, Joos S, Rieker RJ, Agaimy A, Söder S, Reid-Lombardo KM, Kendrick ML, Bardsley MR, Hayashi Y, Asuzu DT, Syed SA, Ordog T, Zörnig M.

Int J Cancer. 2015 Sep 15;137(6):1318-29. doi: 10.1002/ijc.29498. Epub 2015 Mar 12.

34.

Stem cells for murine interstitial cells of cajal suppress cellular immunity and colitis via prostaglandin E2 secretion.

Dave M, Hayashi Y, Gajdos GB, Smyrk TC, Svingen PA, Kvasha SM, Lorincz A, Dong H, Faubion WA Jr, Ordog T.

Gastroenterology. 2015 May;148(5):978-90. doi: 10.1053/j.gastro.2015.01.036. Epub 2015 Jan 28.

35.

Acute depletion redefines the division of labor among DNA methyltransferases in methylating the human genome.

Tiedemann RL, Putiri EL, Lee JH, Hlady RA, Kashiwagi K, Ordog T, Zhang Z, Liu C, Choi JH, Robertson KD.

Cell Rep. 2014 Nov 20;9(4):1554-66. doi: 10.1016/j.celrep.2014.10.013. Epub 2014 Nov 6.

36.

Strand-specific analysis shows protein binding at replication forks and PCNA unloading from lagging strands when forks stall.

Yu C, Gan H, Han J, Zhou ZX, Jia S, Chabes A, Farrugia G, Ordog T, Zhang Z.

Mol Cell. 2014 Nov 20;56(4):551-63. doi: 10.1016/j.molcel.2014.09.017. Epub 2014 Oct 23. Erratum in: Mol Cell. 2014 Nov 20;56(4):609.

37.

Identification and characterization of a novel promoter for the human ANO1 gene regulated by the transcription factor signal transducer and activator of transcription 6 (STAT6).

Mazzone A, Gibbons SJ, Bernard CE, Nowsheen S, Middha S, Almada LL, Ordog T, Kendrick ML, Reid Lombardo KM, Shen KR, Galietta LJ, Fernandez-Zapico ME, Farrugia G.

FASEB J. 2015 Jan;29(1):152-63. doi: 10.1096/fj.14-258541. Epub 2014 Oct 28.

38.

Ano1, a Ca2+-activated Cl- channel, coordinates contractility in mouse intestine by Ca2+ transient coordination between interstitial cells of Cajal.

Singh RD, Gibbons SJ, Saravanaperumal SA, Du P, Hennig GW, Eisenman ST, Mazzone A, Hayashi Y, Cao C, Stoltz GJ, Ordog T, Rock JR, Harfe BD, Szurszewski JH, Farrugia G.

J Physiol. 2014 Sep 15;592(18):4051-68. doi: 10.1113/jphysiol.2014.277152. Epub 2014 Jul 25.

39.

Aberrant signature methylome by DNMT1 hot spot mutation in hereditary sensory and autonomic neuropathy 1E.

Sun Z, Wu Y, Ordog T, Baheti S, Nie J, Duan X, Hojo K, Kocher JP, Dyck PJ, Klein CJ.

Epigenetics. 2014 Aug;9(8):1184-93. doi: 10.4161/epi.29676. Epub 2014 Jul 7.

40.

Dystrophin is a tumor suppressor in human cancers with myogenic programs.

Wang Y, Marino-Enriquez A, Bennett RR, Zhu M, Shen Y, Eilers G, Lee JC, Henze J, Fletcher BS, Gu Z, Fox EA, Antonescu CR, Fletcher CD, Guo X, Raut CP, Demetri GD, van de Rijn M, Ordog T, Kunkel LM, Fletcher JA.

Nat Genet. 2014 Jun;46(6):601-6. doi: 10.1038/ng.2974. Epub 2014 May 4.

41.

Vascular endothelial growth factor promotes fibrosis resolution and repair in mice.

Yang L, Kwon J, Popov Y, Gajdos GB, Ordog T, Brekken RA, Mukhopadhyay D, Schuppan D, Bi Y, Simonetto D, Shah VH.

Gastroenterology. 2014 May;146(5):1339-50.e1. doi: 10.1053/j.gastro.2014.01.061. Epub 2014 Feb 4.

42.

Membrane-to-nucleus signaling links insulin-like growth factor-1- and stem cell factor-activated pathways.

Hayashi Y, Asuzu DT, Gibbons SJ, Aarsvold KH, Bardsley MR, Lomberk GA, Mathison AJ, Kendrick ML, Shen KR, Taguchi T, Gupta A, Rubin BP, Fletcher JA, Farrugia G, Urrutia RA, Ordog T.

PLoS One. 2013 Oct 7;8(10):e76822. doi: 10.1371/journal.pone.0076822. eCollection 2013.

43.

Epigenetics and chromatin dynamics: a review and a paradigm for functional disorders.

Ordog T, Syed SA, Hayashi Y, Asuzu DT.

Neurogastroenterol Motil. 2012 Dec;24(12):1054-68. doi: 10.1111/nmo.12031. Epub 2012 Oct 24. Review.

44.

Inhibition of cell proliferation by a selective inhibitor of the Ca(2+)-activated Cl(-) channel, Ano1.

Mazzone A, Eisenman ST, Strege PR, Yao Z, Ordog T, Gibbons SJ, Farrugia G.

Biochem Biophys Res Commun. 2012 Oct 19;427(2):248-53. doi: 10.1016/j.bbrc.2012.09.022. Epub 2012 Sep 17.

45.

Platelet-derived growth factor receptor α (PDGFRα)-expressing "fibroblast-like cells" in diabetic and idiopathic gastroparesis of humans.

Grover M, Bernard CE, Pasricha PJ, Parkman HP, Abell TL, Nguyen LA, Snape W, Shen KR, Sarr M, Swain J, Kendrick M, Gibbons S, Ordog T, Farrugia G.

Neurogastroenterol Motil. 2012 Sep;24(9):844-52. doi: 10.1111/j.1365-2982.2012.01944.x. Epub 2012 Jun 1.

46.

Ano1 as a regulator of proliferation.

Stanich JE, Gibbons SJ, Eisenman ST, Bardsley MR, Rock JR, Harfe BD, Ordog T, Farrugia G.

Am J Physiol Gastrointest Liver Physiol. 2011 Dec;301(6):G1044-51. doi: 10.1152/ajpgi.00196.2011. Epub 2011 Sep 22.

47.

Generalized neuromuscular hypoplasia, reduced smooth muscle myosin and altered gut motility in the klotho model of premature aging.

Asuzu DT, Hayashi Y, Izbeki F, Popko LN, Young DL, Bardsley MR, Lorincz A, Kuro-O M, Linden DR, Farrugia G, Ordog T.

Neurogastroenterol Motil. 2011 Jul;23(7):e309-23. doi: 10.1111/j.1365-2982.2011.01730.x. Epub 2011 May 24.

48.

Immunoreactivity for Ano1 detects depletion of Kit-positive interstitial cells of Cajal in patients with slow transit constipation.

Kashyap P, Gomez-Pinilla PJ, Pozo MJ, Cima RR, Dozois EJ, Larson DW, Ordog T, Gibbons SJ, Farrugia G.

Neurogastroenterol Motil. 2011 Aug;23(8):760-5. doi: 10.1111/j.1365-2982.2011.01729.x. Epub 2011 May 17.

49.

Altered expression of Ano1 variants in human diabetic gastroparesis.

Mazzone A, Bernard CE, Strege PR, Beyder A, Galietta LJ, Pasricha PJ, Rae JL, Parkman HP, Linden DR, Szurszewski JH, Ördög T, Gibbons SJ, Farrugia G.

J Biol Chem. 2011 Apr 15;286(15):13393-403. doi: 10.1074/jbc.M110.196089. Epub 2011 Feb 24.

50.

Polycomb and the emerging epigenetics of pancreatic cancer.

Grzenda A, Ordog T, Urrutia R.

J Gastrointest Cancer. 2011 Jun;42(2):100-11. doi: 10.1007/s12029-011-9262-4. Review.

Supplemental Content

Support Center