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Items: 1 to 50 of 70

1.

Efficacy of venetoclax monotherapy in patients with relapsed chronic lymphocytic leukaemia in the post-BCR inhibitor setting: a UK wide analysis.

Eyre TA, Kirkwood AA, Gohill S, Follows G, Walewska R, Walter H, Cross M, Forconi F, Shah N, Chasty R, Hart A, Broom A, Marr H, Patten PEM, Dann A, Arumainathan A, Munir T, Shankara P, Bloor A, Johnston R, Orchard K, Schuh AH, Fox CP; the UK CLL Forum.

Br J Haematol. 2019 May;185(4):656-669. doi: 10.1111/bjh.15802. Epub 2019 Feb 15.

PMID:
30768675
2.

ZnSe Nanorods as Visible-Light Absorbers for Photocatalytic and Photoelectrochemical H2 Evolution in Water.

Kuehnel MF, Creissen CE, Sahm CD, Wielend D, Schlosser A, Orchard KL, Reisner E.

Angew Chem Int Ed Engl. 2019 Apr 1;58(15):5059-5063. doi: 10.1002/anie.201814265. Epub 2019 Mar 6.

3.

Antigenic Targets for the Immunotherapy of Acute Myeloid Leukaemia.

Khan GN, Orchard K, Guinn BA.

J Clin Med. 2019 Jan 23;8(2). pii: E134. doi: 10.3390/jcm8020134. Review.

4.

Mesenchymal stromal cells for acute graft-versus-host disease: response at 1 week predicts probability of survival.

Galleu A, Milojkovic D, Deplano S, Szydlo R, Loaiza S, Wynn R, Marks DI, Richardson D, Orchard K, Kanfer E, Tholouli E, Saif M, Sivaprakasam P, Lawson S, Bloor A, Pagliuca A, Potter V, Mehra V, Snowden JA, Vora A, Kishore B, Hunter H, Apperley JF, Dazzi F.

Br J Haematol. 2019 Apr;185(1):89-92. doi: 10.1111/bjh.15749. Epub 2019 Jan 13.

5.

Use of coping strategies in multiple sclerosis: Association with demographic and disease-related characteristics.

Holland DP, Schlüter DK, Young CA, Mills RJ, Rog DJ, Ford HL, Orchard K; TONiC study group.

Mult Scler Relat Disord. 2019 Jan;27:214-222. doi: 10.1016/j.msard.2018.10.016. Epub 2018 Oct 22.

PMID:
30412819
6.

Aerobic Conditions Enhance the Photocatalytic Stability of CdS/CdOx Quantum Dots.

Wakerley DW, Ly KH, Kornienko N, Orchard KL, Kuehnel MF, Reisner E.

Chemistry. 2018 Dec 10;24(69):18385-18388. doi: 10.1002/chem.201802353. Epub 2018 Jun 27.

7.

ZnSe quantum dots modified with a Ni(cyclam) catalyst for efficient visible-light driven CO2 reduction in water.

Kuehnel MF, Sahm CD, Neri G, Lee JR, Orchard KL, Cowan AJ, Reisner E.

Chem Sci. 2018 Jan 24;9(9):2501-2509. doi: 10.1039/c7sc04429a. eCollection 2018 Mar 7.

8.

Layered zinc hydroxide monolayers by hydrolysis of organozincs.

Leung AHM, Pike SD, Clancy AJ, Yau HC, Lee WJ, Orchard KL, Shaffer MSP, Williams CK.

Chem Sci. 2018 Jan 25;9(8):2135-2146. doi: 10.1039/c7sc04256f. eCollection 2018 Feb 28.

9.

Cyclophosphamide versus etoposide in combination with total body irradiation as conditioning regimen for adult patients with Ph-negative acute lymphoblastic leukemia undergoing allogeneic stem cell transplant: On behalf of the ALWP of the European Society for Blood and Marrow Transplantation.

Czyz A, Labopin M, Giebel S, Socié G, Apperley J, Volin L, Reményi P, Yakoub-Agha I, Orchard K, Michallet M, Stuhler G, Chaganti S, Murray M, Aljurf M, Bloor A, Passweg J, Finke J, Mohty M, Nagler A.

Am J Hematol. 2018 Jun;93(6):778-785. doi: 10.1002/ajh.25091. Epub 2018 Mar 30.

10.

Identification of survivin as a promising target for the immunotherapy of adult B-cell acute lymphoblastic leukemia.

Boullosa LF, Savaliya P, Bonney S, Orchard L, Wickenden H, Lee C, Smits E, Banham AH, Mills KI, Orchard K, Guinn BA.

Oncotarget. 2017 Dec 17;9(3):3853-3866. doi: 10.18632/oncotarget.23380. eCollection 2018 Jan 9.

11.

Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation.

Galleu A, Riffo-Vasquez Y, Trento C, Lomas C, Dolcetti L, Cheung TS, von Bonin M, Barbieri L, Halai K, Ward S, Weng L, Chakraverty R, Lombardi G, Watt FM, Orchard K, Marks DI, Apperley J, Bornhauser M, Walczak H, Bennett C, Dazzi F.

Sci Transl Med. 2017 Nov 15;9(416). pii: eaam7828. doi: 10.1126/scitranslmed.aam7828.

12.

Catechol-TiO2 hybrids for photocatalytic H2 production and photocathode assembly.

Orchard KL, Hojo D, Sokol KP, Chan MJ, Asao N, Adschiri T, Reisner E.

Chem Commun (Camb). 2017 Nov 23;53(94):12638-12641. doi: 10.1039/c7cc05094a.

PMID:
29119188
13.

Exploring Step-by-Step Assembly of Nanoparticle:Cytochrome Biohybrid Photoanodes.

Hwang ET, Orchard KL, Hojo D, Beton J, Lockwood CWJ, Adschiri T, Butt JN, Reisner E, Jeuken LJC.

ChemElectroChem. 2017 Aug;4(8):1959-1968. doi: 10.1002/celc.201700030. Epub 2017 May 15.

14.

Radioimmunotherapy-augmented BEAM chemotherapy vs BEAM alone as the high-dose regimen for autologous stem cell transplantation (ASCT) in relapsed follicular lymphoma (FL): a retrospective study of the EBMT Lymphoma Working Party.

Bento L, Boumendil A, Finel H, Le Gouill S, Amorim S, Monjanel H, Bouabdallah R, Bay JO, Nicolas-Virelizier E, McQuaker G, Rossi G, Johnson R, Huynh A, Ceballos P, Rambaldi A, Bachy E, Malladi R, Orchard K, Pohlreich D, Tilly H, Bonifazi F, Poiré X, Guilhot F, Haenel A, Crawley C, Metzner B, Gribben J, Russell NH, Damaj G, Thomson K, Dreger P, Montoto S.

Bone Marrow Transplant. 2017 Aug;52(8):1120-1125. doi: 10.1038/bmt.2017.88. Epub 2017 May 22.

PMID:
28530668
15.

Selective Photocatalytic CO2 Reduction in Water through Anchoring of a Molecular Ni Catalyst on CdS Nanocrystals.

Kuehnel MF, Orchard KL, Dalle KE, Reisner E.

J Am Chem Soc. 2017 May 31;139(21):7217-7223. doi: 10.1021/jacs.7b00369. Epub 2017 May 18.

PMID:
28467076
16.

JACIE accreditation for blood and marrow transplantation: past, present and future directions of an international model for healthcare quality improvement.

Snowden JA, McGrath E, Duarte RF, Saccardi R, Orchard K, Worel N, Kuball J, Chabannon C, Mohty M.

Bone Marrow Transplant. 2017 Oct;52(10):1367-1371. doi: 10.1038/bmt.2017.54. Epub 2017 Mar 27.

17.

Photoelectrochemical hydrogen production in water using a layer-by-layer assembly of a Ru dye and Ni catalyst on NiO.

Gross MA, Creissen CE, Orchard KL, Reisner E.

Chem Sci. 2016 Aug 1;7(8):5537-5546. doi: 10.1039/c6sc00715e. Epub 2016 May 9.

18.

Dye-sensitised semiconductors modified with molecular catalysts for light-driven H2 production.

Willkomm J, Orchard KL, Reynal A, Pastor E, Durrant JR, Reisner E.

Chem Soc Rev. 2016 Jan 7;45(1):9-23. doi: 10.1039/c5cs00733j.

19.

Application of the pMHC Array to Characterise Tumour Antigen Specific T Cell Populations in Leukaemia Patients at Disease Diagnosis.

Brooks SE, Bonney SA, Lee C, Publicover A, Khan G, Smits EL, Sigurdardottir D, Arno M, Li D, Mills KI, Pulford K, Banham AH, van Tendeloo V, Mufti GJ, Rammensee HG, Elliott TJ, Orchard KH, Guinn BA.

PLoS One. 2015 Oct 22;10(10):e0140483. doi: 10.1371/journal.pone.0140483. eCollection 2015.

20.

Allogeneic haematopoietic stem cell transplantation for mitochondrial neurogastrointestinal encephalomyopathy.

Halter JP, Michael W, Schüpbach M, Mandel H, Casali C, Orchard K, Collin M, Valcarcel D, Rovelli A, Filosto M, Dotti MT, Marotta G, Pintos G, Barba P, Accarino A, Ferra C, Illa I, Beguin Y, Bakker JA, Boelens JJ, de Coo IF, Fay K, Sue CM, Nachbaur D, Zoller H, Sobreira C, Pinto Simoes B, Hammans SR, Savage D, Martí R, Chinnery PF, Elhasid R, Gratwohl A, Hirano M.

Brain. 2015 Oct;138(Pt 10):2847-58. doi: 10.1093/brain/awv226. Epub 2015 Aug 10.

21.

Photocatalytic Formic Acid Conversion on CdS Nanocrystals with Controllable Selectivity for H2 or CO.

Kuehnel MF, Wakerley DW, Orchard KL, Reisner E.

Angew Chem Int Ed Engl. 2015 Aug 10;54(33):9627-31. doi: 10.1002/anie.201502773. Epub 2015 Jul 16.

22.

A Decaheme Cytochrome as a Molecular Electron Conduit in Dye-Sensitized Photoanodes.

Hwang ET, Sheikh K, Orchard KL, Hojo D, Radu V, Lee CY, Ainsworth E, Lockwood C, Gross MA, Adschiri T, Reisner E, Butt JN, Jeuken LJ.

Adv Funct Mater. 2015 Apr;25(15):2308-2315. Epub 2015 Mar 11.

23.

Idiotypic DNA vaccination for the treatment of multiple myeloma: safety and immunogenicity in a phase I clinical study.

McCann KJ, Godeseth R, Chudley L, Mander A, Di Genova G, Lloyd-Evans P, Kerr JP, Malykh VB, Jenner MW, Orchard KH, Stevenson FK, Ottensmeier CH.

Cancer Immunol Immunother. 2015 Aug;64(8):1021-32. doi: 10.1007/s00262-015-1703-7. Epub 2015 May 16.

24.

Patient-reported outcomes in routine cancer clinical practice: a scoping review of use, impact on health outcomes, and implementation factors.

Howell D, Molloy S, Wilkinson K, Green E, Orchard K, Wang K, Liberty J.

Ann Oncol. 2015 Sep;26(9):1846-58. doi: 10.1093/annonc/mdv181. Epub 2015 Apr 17. Review.

PMID:
25888610
25.

Development of an ELISA for the Pharmacokinetic Evaluation of a Murine Anti CD66 Monoclonal Antibody in Human Serum.

Langford J, Chowdhury F, Orchard K.

J Immunoassay Immunochem. 2015;36(6):579-96. doi: 10.1080/15321819.2015.1017107.

PMID:
25715051
26.

A retrospective multi-centre study of the effects of allogeneic haematopoietic SCT on pulmonary function.

Dharmagunawardena R, Pearce RM, Thomas G, Kirkland K, Perry J, Apperley JF, Medd P, Wilson KM, Orchard K, Jackson G, Snowden JA, Cook G, Brown JS.

Bone Marrow Transplant. 2014 Nov;49(11):1442-3. doi: 10.1038/bmt.2014.154. Epub 2014 Jul 21. No abstract available.

PMID:
25046217
27.

Biosimilar G-CSF based mobilization of peripheral blood hematopoietic stem cells for autologous and allogeneic stem cell transplantation.

Schmitt M, Publicover A, Orchard KH, Görlach M, Wang L, Schmitt A, Mani J, Tsirigotis P, Kuriakose R, Nagler A.

Theranostics. 2014 Jan 23;4(3):280-9. doi: 10.7150/thno.7752. eCollection 2014. Review.

28.

Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2.

Nangalia J, Massie CE, Baxter EJ, Nice FL, Gundem G, Wedge DC, Avezov E, Li J, Kollmann K, Kent DG, Aziz A, Godfrey AL, Hinton J, Martincorena I, Van Loo P, Jones AV, Guglielmelli P, Tarpey P, Harding HP, Fitzpatrick JD, Goudie CT, Ortmann CA, Loughran SJ, Raine K, Jones DR, Butler AP, Teague JW, O'Meara S, McLaren S, Bianchi M, Silber Y, Dimitropoulou D, Bloxham D, Mudie L, Maddison M, Robinson B, Keohane C, Maclean C, Hill K, Orchard K, Tauro S, Du MQ, Greaves M, Bowen D, Huntly BJP, Harrison CN, Cross NCP, Ron D, Vannucchi AM, Papaemmanuil E, Campbell PJ, Green AR.

N Engl J Med. 2013 Dec 19;369(25):2391-2405. doi: 10.1056/NEJMoa1312542. Epub 2013 Dec 10.

29.

EBV-associated post-transplant lymphoproliferative disorder following in vivo T-cell-depleted allogeneic transplantation: clinical features, viral load correlates and prognostic factors in the rituximab era.

Fox CP, Burns D, Parker AN, Peggs KS, Harvey CM, Natarajan S, Marks DI, Jackson B, Chakupurakal G, Dennis M, Lim Z, Cook G, Carpenter B, Pettitt AR, Mathew S, Connelly-Smith L, Yin JA, Viskaduraki M, Chakraverty R, Orchard K, Shaw BE, Byrne JL, Brookes C, Craddock CF, Chaganti S.

Bone Marrow Transplant. 2014 Feb;49(2):280-6. doi: 10.1038/bmt.2013.170. Epub 2013 Nov 11.

PMID:
24212561
30.

Distinctive emotional responses of clinicians to suicide-attempting patients--a comparative study.

Yaseen ZS, Briggs J, Kopeykina I, Orchard KM, Silberlicht J, Bhingradia H, Galynker II.

BMC Psychiatry. 2013 Sep 22;13:230. doi: 10.1186/1471-244X-13-230.

31.

Use of a biosimilar granulocyte colony-stimulating factor for peripheral blood stem cell mobilization: an analysis of mobilization and engraftment.

Publicover A, Richardson DS, Davies A, Hill KS, Hurlock C, Hutchins D, Jenner MW, Johnson PW, Lamb J, Launders H, McKeag N, Newman J, Orchard KH.

Br J Haematol. 2013 Jul;162(1):107-11. doi: 10.1111/bjh.12345. Epub 2013 Apr 25.

PMID:
23614650
32.

Mumps virus encephalomyelitis in a 19-year old male patient with an undefined severe combined immunodeficiency post-haematopoietic bone marrow transplantation: a rare fatal complication.

Eyre TA, Pelosi E, McQuaid S, Richardson D, Newman J, Hill K, Veys P, Davies G, Orchard KH.

J Clin Virol. 2013 Jun;57(2):165-8. doi: 10.1016/j.jcv.2013.02.003. Epub 2013 Feb 26.

PMID:
23485346
33.

Expression of CD66 in non-Hodgkin lymphomas and multiple myeloma.

Guinn BA, Bosslet K, Lee C, Richardson D, Orchard K.

Eur J Haematol. 2011 Dec;87(6):554-5. doi: 10.1111/j.1600-0609.2011.01698.x. Epub 2011 Oct 2. No abstract available.

PMID:
21883478
34.

Development and validation of the 57Co assay for determining the ligand to antibody ratio in bifunctional chelate/antibody conjugates for use in radioimmunotherapy.

Langford JH, Cooper MS, Orchard KH.

Nucl Med Biol. 2011 Nov;38(8):1103-10. doi: 10.1016/j.nucmedbio.2011.05.002. Epub 2011 Jul 7.

PMID:
21741259
35.

Clinical evaluation of cellular immunotherapy in acute myeloid leukaemia.

Smits EL, Lee C, Hardwick N, Brooks S, Van Tendeloo VF, Orchard K, Guinn BA.

Cancer Immunol Immunother. 2011 Jun;60(6):757-69. doi: 10.1007/s00262-011-1022-6. Epub 2011 Apr 26. Review.

PMID:
21519825
36.

Allogeneic hematopoietic SCT as treatment option for patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): a consensus conference proposal for a standardized approach.

Halter J, Schüpbach W, Casali C, Elhasid R, Fay K, Hammans S, Illa I, Kappeler L, Krähenbühl S, Lehmann T, Mandel H, Marti R, Mattle H, Orchard K, Savage D, Sue CM, Valcarcel D, Gratwohl A, Hirano M.

Bone Marrow Transplant. 2011 Mar;46(3):330-337. doi: 10.1038/bmt.2010.100. Epub 2010 May 3.

37.

Outcome following Reduced-Intensity Allogeneic Stem Cell Transplantation (RIC AlloSCT) for relapsed and refractory mantle cell lymphoma (MCL): a study of the British Society for Blood and Marrow Transplantation.

Cook G, Smith GM, Kirkland K, Lee J, Pearce R, Thomson K, Morris E, Orchard K, Rule S, Russell N, Craddock C, Marks DI; Clinical Trials Committee (CTC) of the British Society for Blood and Marrow Transplantation (BSBMT).

Biol Blood Marrow Transplant. 2010 Oct;16(10):1419-27. doi: 10.1016/j.bbmt.2010.04.006. Epub 2010 Apr 24.

38.

CD66a (CEACAM1) is the only CD66 variant expressed on the surface of plasma cells in multiple myeloma: a refined target for radiotherapy trials?

Lee C, Guinn BA, Brooks SE, Richardson D, Orchard K.

Br J Haematol. 2010 Jun;149(5):795-6. doi: 10.1111/j.1365-2141.2010.08100.x. Epub 2010 Mar 21. No abstract available.

PMID:
20230402
39.

Timing of acquisition of deletion 13 in plasma cell dyscrasias is dependent on genetic context.

Chiecchio L, Dagrada GP, Ibrahim AH, Dachs Cabanas E, Protheroe RK, Stockley DM, Orchard KH, Cross NC, Harrison CJ, Ross FM; UK Myeloma Forum.

Haematologica. 2009 Dec;94(12):1708-13. doi: 10.3324/haematol.2009.011064.

40.

One-pot, in situ synthesis of ZnO-carbon nanotube-epoxy resin hybrid nanocomposites.

González-Campo A, Orchard KL, Sato N, Shaffer MS, Williams CK.

Chem Commun (Camb). 2009 Jul 21;(27):4034-6. doi: 10.1039/b905353k. Epub 2009 Jun 9.

41.

Loss of 1p and rearrangement of MYC are associated with progression of smouldering myeloma to myeloma: sequential analysis of a single case.

Chiecchio L, Dagrada GP, Protheroe RK, Stockley DM, Smith AG, Orchard KH, Cross NC, Harrison CJ, Ross FM; UK Myeloma Forum.

Haematologica. 2009 Jul;94(7):1024-8. doi: 10.3324/haematol.2008.004440. Epub 2009 May 19.

42.

Frequent upregulation of MYC in plasma cell leukemia.

Chiecchio L, Dagrada GP, White HE, Towsend MR, Protheroe RK, Cheung KL, Stockley DM, Orchard KH, Cross NC, Harrison CJ, Ross FM; UK Myeloma Forum.

Genes Chromosomes Cancer. 2009 Jul;48(7):624-36. doi: 10.1002/gcc.20670.

PMID:
19396865
43.

Alemtuzumab markedly reduces chronic GVHD without affecting overall survival in reduced-intensity conditioning sibling allo-SCT for adults with AML.

Malladi RK, Peniket AJ, Littlewood TJ, Towlson KE, Pearce R, Yin J, Cavenagh JD, Craddock C, Orchard KH, Olavarria E, McQuaker G, Collin M, Marks DI; British Society of Blood and Marrow Transplantation.

Bone Marrow Transplant. 2009 May;43(9):709-15. doi: 10.1038/bmt.2008.375. Epub 2008 Nov 24.

PMID:
19029965
44.

Long-term outcomes of myeloablation and autologous transplantation of relapsed acute myeloid leukemia in second remission: a British Society of Blood and Marrow Transplantation registry study.

Chantry AD, Snowden JA, Craddock C, Peggs K, Roddie C, Craig JI, Orchard K, Towlson KE, Pearce RM, Marks DI; BSBMT Clinical Trials Committee.

Biol Blood Marrow Transplant. 2006 Dec;12(12):1310-7.

45.

Deletion of chromosome 13 detected by conventional cytogenetics is a critical prognostic factor in myeloma.

Chiecchio L, Protheroe RK, Ibrahim AH, Cheung KL, Rudduck C, Dagrada GP, Cabanas ED, Parker T, Nightingale M, Wechalekar A, Orchard KH, Harrison CJ, Cross NC, Morgan GJ, Ross FM.

Leukemia. 2006 Sep;20(9):1610-7. Epub 2006 Jul 6.

PMID:
16826223
46.

Selective apoptotic killing of malignant hemopoietic cells by antibody-targeted delivery of an amphipathic peptide.

Marks AJ, Cooper MS, Anderson RJ, Orchard KH, Hale G, North JM, Ganeshaguru K, Steele AJ, Mehta AB, Lowdell MW, Wickremasinghe RG.

Cancer Res. 2005 Mar 15;65(6):2373-7.

47.

Targeting the bone marrow: applications in stem cell transplantation.

Orchard K, Cooper M.

Q J Nucl Med Mol Imaging. 2004 Dec;48(4):267-78. Review.

48.

Autologous/syngeneic stem cell transplantation to treat refractory GvHD.

Passweg JR, Orchard K, Buergi A, Gratwohl A, Powles R, Goldman J, Apperley J, Mehta J.

Bone Marrow Transplant. 2004 Dec;34(11):995-8.

PMID:
15489881
49.

The development of an accredited bowel-management course.

Chivers M, Broadbridge J, Jarvis C, Orchard K.

Nurs Times. 2004 Jan 13-19;100(2):58-60.

PMID:
14768157
50.

Cytogenetics of multiple myeloma: interpretation of fluorescence in situ hybridization results.

Harrison CJ, Mazzullo H, Cheung KL, Gerrard G, Jalali GR, Mehta A, Osier DG, Orchard KH.

Br J Haematol. 2003 Mar;120(6):944-52.

PMID:
12648063

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