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Items: 1 to 50 of 180


J-Waves in Epicardial Electrograms Can Guide Ablation of Arrhythmogenic Substrates.

Boukens BJ, Opthof T, Coronel R.

Circ Res. 2019 Jan 18;124(2):205-207. doi: 10.1161/CIRCRESAHA.118.314414. No abstract available.


The electrocardiogram of vertebrates: Evolutionary changes from ectothermy to endothermy.

Boukens BJD, Kristensen DL, Filogonio R, Carreira LBT, Sartori MR, Abe AS, Currie S, Joyce W, Conner J, Opthof T, Crossley DA 2nd, Wang T, Jensen B.

Prog Biophys Mol Biol. 2018 Sep 19. pii: S0079-6107(18)30022-1. doi: 10.1016/j.pbiomolbio.2018.08.005. [Epub ahead of print] Review.


Quantification of sympathetic hyperinnervation and denervation after myocardial infarction by three-dimensional assessment of the cardiac sympathetic network in cleared transparent murine hearts.

Yokoyama T, Lee JK, Miwa K, Opthof T, Tomoyama S, Nakanishi H, Yoshida A, Yasui H, Iida T, Miyagawa S, Okabe S, Sawa Y, Sakata Y, Komuro I.

PLoS One. 2017 Jul 28;12(7):e0182072. doi: 10.1371/journal.pone.0182072. eCollection 2017.


Local transmural action potential gradients are absent in the isolated, intact dog heart but present in the corresponding coronary-perfused wedge.

Boukens BJ, Meijborg VMF, Belterman CN, Opthof T, Janse MJ, Schuessler RB, Coronel R, Efimov IR.

Physiol Rep. 2017 May;5(10). pii: e13251. doi: 10.14814/phy2.13251.


Cardiac activation-repolarization patterns and ion channel expression mapping in intact isolated normal human hearts.

Opthof T, Remme CA, Jorge E, Noriega F, Wiegerinck RF, Tasiam A, Beekman L, Alvarez-Garcia J, Munoz-Guijosa C, Coronel R, Cinca J.

Heart Rhythm. 2017 Feb;14(2):265-272. doi: 10.1016/j.hrthm.2016.10.010. Epub 2016 Oct 11.


Increased Late Sodium Current Contributes to the Electrophysiological Effects of Chronic, but Not Acute, Dofetilide Administration.

Qiu XS, Chauveau S, Anyukhovsky EP, Rahim T, Jiang YP, Harleton E, Feinmark SJ, Lin RZ, Coronel R, Janse MJ, Opthof T, Rosen TS, Cohen IS, Rosen MR.

Circ Arrhythm Electrophysiol. 2016 Apr;9(4):e003655. doi: 10.1161/CIRCEP.115.003655.


A New In Vitro Co-Culture Model Using Magnetic Force-Based Nanotechnology.

Takanari H, Miwa K, Fu X, Nakai J, Ito A, Ino K, Honda H, Tonomura W, Konishi S, Opthof T, van der Heyden MA, Kodama I, Lee JK.

J Cell Physiol. 2016 Oct;231(10):2249-56. doi: 10.1002/jcp.25342. Epub 2016 Mar 16.


Dispersion in ventricular repolarization in the human, canine and porcine heart.

Opthof T, Janse MJ, Meijborg VM, Cinca J, Rosen MR, Coronel R.

Prog Biophys Mol Biol. 2016 Jan;120(1-3):222-35. doi: 10.1016/j.pbiomolbio.2016.01.007. Epub 2016 Jan 11. Review.


Synchronization of repolarization by mechano-electrical coupling in the porcine heart.

Opthof T, Meijborg VM, Belterman CN, Coronel R.

Cardiovasc Res. 2015 Oct 1;108(1):181-7. doi: 10.1093/cvr/cvv140. Epub 2015 May 1.


An activation-repolarization time metric to predict localized regions of high susceptibility to reentry.

Child N, Bishop MJ, Hanson B, Coronel R, Opthof T, Boukens BJ, Walton RD, Efimov IR, Bostock J, Hill Y, Rinaldi CA, Razavi R, Gill J, Taggart P.

Heart Rhythm. 2015 Jul;12(7):1644-53. doi: 10.1016/j.hrthm.2015.04.013. Epub 2015 Apr 9.


Interventricular dispersion in repolarization causes bifid T waves in dogs with dofetilide-induced long QT syndrome.

Meijborg VM, Chauveau S, Janse MJ, Anyukhovsky EP, Danilo PR Jr, Rosen MR, Opthof T, Coronel R.

Heart Rhythm. 2015 Jun;12(6):1343-51. doi: 10.1016/j.hrthm.2015.02.026. Epub 2015 Feb 24.


Electrocardiographic T wave and its relation with ventricular repolarization along major anatomical axes.

Meijborg VM, Conrath CE, Opthof T, Belterman CN, de Bakker JM, Coronel R.

Circ Arrhythm Electrophysiol. 2014 Jun;7(3):524-31. doi: 10.1161/CIRCEP.113.001622. Epub 2014 May 16.


Impact factor 2013 of the Netherlands Heart Journal surpasses 2.0.

Opthof T.

Neth Heart J. 2014 Apr;22(4):137-8. doi: 10.1007/s12471-014-0538-8.


Axon guidance of sympathetic neurons to cardiomyocytes by glial cell line-derived neurotrophic factor (GDNF).

Miwa K, Lee JK, Takagishi Y, Opthof T, Fu X, Hirabayashi M, Watabe K, Jimbo Y, Kodama I, Komuro I.

PLoS One. 2013 Jul 3;8(7):e65202. doi: 10.1371/journal.pone.0065202. Print 2013.


The impact factor of the Netherlands Heart Journal in 2013.

Opthof T.

Neth Heart J. 2013 Jul;21(7-8):319-21. doi: 10.1007/s12471-013-0443-6. No abstract available.


Inflation of impact factors by journal self-citation in cardiovascular science.

Opthof T.

Neth Heart J. 2013 Apr;21(4):163-5. doi: 10.1007/s12471-013-0384-0. No abstract available.


Early repolarization in mice causes overestimation of ventricular activation time by the QRS duration.

Boukens BJ, Hoogendijk MG, Verkerk AO, Linnenbank A, van Dam P, Remme CA, Fiolet JW, Opthof T, Christoffels VM, Coronel R.

Cardiovasc Res. 2013 Jan 1;97(1):182-91. doi: 10.1093/cvr/cvs299. Epub 2012 Sep 20.


The works of Dirk Durrer (1918-1984).

Opthof T, Janse MJ, Kléber AG, Wellens HJ, Wilde AA, Coronel R.

Neth Heart J. 2012 Oct;20(10):430-3. doi: 10.1007/s12471-012-0313-7. No abstract available.


The Association of Abnormal Ventricular Wall Motion and Increased Dispersion of Repolarization in Humans is Independent of the Presence of Myocardial Infarction.

Opthof T, Sutton P, Coronel R, Wright S, Kallis P, Taggart P.

Front Physiol. 2012 Jul 3;3:235. doi: 10.3389/fphys.2012.00235. eCollection 2012.


Inhibition of intercellular coupling stabilizes spiral-wave reentry, whereas enhancement of the coupling destabilizes the reentry in favor of early termination.

Takemoto Y, Takanari H, Honjo H, Ueda N, Harada M, Kato S, Yamazaki M, Sakuma I, Opthof T, Kodama I, Kamiya K.

Am J Physiol Heart Circ Physiol. 2012 Sep 1;303(5):H578-86. doi: 10.1152/ajpheart.00355.2012. Epub 2012 Jun 15.


Pharmacological blockade of IKs destabilizes spiral-wave reentry under β-adrenergic stimulation in favor of its early termination.

Kato S, Honjo H, Takemoto Y, Takanari H, Suzuki T, Okuno Y, Opthof T, Sakuma I, Inada S, Nakazawa K, Ashihara T, Kodama I, Kamiya K.

J Pharmacol Sci. 2012;119(1):52-63. Epub 2012 Apr 28.


Repolarization gradients in the intact heart: transmural or apico-basal?

Janse MJ, Coronel R, Opthof T, Sosunov EA, Anyukhovsky EP, Rosen MR.

Prog Biophys Mol Biol. 2012 May;109(1-2):6-15. doi: 10.1016/j.pbiomolbio.2012.03.001. Epub 2012 Mar 15. Review.


Postrepolarization refractoriness in acute ischemia and after antiarrhythmic drug administration: action potential duration is not always an index of the refractory period.

Coronel R, Janse MJ, Opthof T, Wilde AA, Taggart P.

Heart Rhythm. 2012 Jun;9(6):977-82. doi: 10.1016/j.hrthm.2012.01.021. Epub 2012 Jan 28. Review.


A rejoinder on energy versus impact indicators.

Leydesdorff L, Opthof T.

Scientometrics. 2012 Feb;90(2):745-748. Epub 2011 Sep 20.


Letter by Opthof et al regarding article, "Prolonged Tpeak to tend interval on the resting electrocardiogram is associated with increased risk of sudden cardiac death".

Opthof T, Janse MJ, Coronel R.

Circ Arrhythm Electrophysiol. 2011 Dec;4(6):e87; author reply e88. doi: 10.1161/CIRCEP.111.965566. No abstract available.


A comment to the paper by Waltman et al., Scientometrics, 87, 467-481, 2011.

Opthof T, Leydesdorff L.

Scientometrics. 2011 Sep;88(3):1011-1016. Epub 2011 Jun 17.


Impact factor of the Chinese Journal of Physiology in 2009: meet the readers.

van der Heyden MA, Opthof T.

Chin J Physiol. 2010 Aug 31;53(4):268-9. No abstract available.


One more time: bibliometric analysis of scientific output remains complicated.

Opthof T, Wilde AA.

Neth Heart J. 2011 Aug;19(7-8):359-60. doi: 10.1007/s12471-011-0180-7. No abstract available.


A single intracoronary injection of midkine reduces ischemia/reperfusion injury in Swine hearts: a novel therapeutic approach for acute coronary syndrome.

Ishiguro H, Horiba M, Takenaka H, Sumida A, Opthof T, Ishiguro YS, Kadomatsu K, Murohara T, Kodama I.

Front Physiol. 2011 Jun 23;2:27. doi: 10.3389/fphys.2011.00027. eCollection 2011.


Rebuttal to M cells are present in the ventricular myocardium. Counterpoint.

Janse MJ, Coronel R, Opthof T.

Heart Rhythm. 2011 Jul;8(7):1100. doi: 10.1016/j.hrthm.2011.04.028. No abstract available.


Reconstituted high-density lipoprotein shortens cardiac repolarization.

Den Ruijter HM, Franssen R, Verkerk AO, van Wijk DF, Vaessen SF, Holleboom AG, Levels JH, Opthof T, Sungnoon R, Stroes ES, Kuivenhoven JA, Coronel R.

J Am Coll Cardiol. 2011 Jun 28;58(1):40-4. doi: 10.1016/j.jacc.2010.11.072.


Differences in citation frequency of clinical and basic science papers in cardiovascular research.

Opthof T.

Med Biol Eng Comput. 2011 Jun;49(6):613-21. doi: 10.1007/s11517-011-0783-6. Epub 2011 May 13.


Bibliometric data in clinical cardiology revisited. The case of 37 Dutch professors.

Opthof T, Wilde AA.

Neth Heart J. 2011 May;19(5):246-55. doi: 10.1007/s12471-011-0128-y.


Counterpoint: M cells do not have a functional role in the ventricular myocardium of the intact heart.

Janse MJ, Coronel R, Opthof T.

Heart Rhythm. 2011 Jun;8(6):934-7. doi: 10.1016/j.hrthm.2010.10.048. Epub 2011 Jan 15. Review. No abstract available.


Bepridil facilitates early termination of spiral-wave reentry in two-dimensional cardiac muscle through an increase of intercellular electrical coupling.

Takanari H, Honjo H, Takemoto Y, Suzuki T, Kato S, Harada M, Okuno Y, Ashihara T, Opthof T, Sakuma I, Kamiya K, Kodama I.

J Pharmacol Sci. 2011;115(1):15-26. Epub 2010 Dec 9.


The Brugada ECG pattern: a marker of channelopathy, structural heart disease, or neither? Toward a unifying mechanism of the Brugada syndrome.

Hoogendijk MG, Opthof T, Postema PG, Wilde AA, de Bakker JM, Coronel R.

Circ Arrhythm Electrophysiol. 2010 Jun;3(3):283-90. doi: 10.1161/CIRCEP.110.937029. Review. No abstract available.


Cardiac expression of skeletal muscle sodium channels increases longitudinal conduction velocity in the canine 1-week myocardial infarction.

Coronel R, Lau DH, Sosunov EA, Janse MJ, Danilo P Jr, Anyukhovsky EP, Wilms-Schopman FJ, Opthof T, Shlapakova IN, Ozgen N, Prestia K, Kryukova Y, Cohen IS, Robinson RB, Rosen MR.

Heart Rhythm. 2010 Aug;7(8):1104-10. doi: 10.1016/j.hrthm.2010.04.009. Epub 2010 Apr 10.


The anti-protozoal drug pentamidine blocks KIR2.x-mediated inward rectifier current by entering the cytoplasmic pore region of the channel.

de Boer TP, Nalos L, Stary A, Kok B, Houtman MJ, Antoons G, van Veen TA, Beekman JD, de Groot BL, Opthof T, Rook MB, Vos MA, van der Heyden MA.

Br J Pharmacol. 2010 Apr;159(7):1532-41. doi: 10.1111/j.1476-5381.2010.00658.x. Epub 2010 Feb 24.


Comparative study of nifekalant versus amiodarone for shock-resistant ventricular fibrillation in out-of-hospital cardiopulmonary arrest patients.

Amino M, Yoshioka K, Opthof T, Morita S, Uemura S, Tamura K, Fukushima T, Higami S, Otsuka H, Akieda K, Shima M, Fujibayashi D, Hashida T, Inokuchi S, Kodama I, Tanabe T.

J Cardiovasc Pharmacol. 2010 Apr;55(4):391-8. doi: 10.1097/FJC.0b013e3181d3dcc7.


Midkine gene transfer after myocardial infarction in rats prevents remodelling and ameliorates cardiac dysfunction.

Sumida A, Horiba M, Ishiguro H, Takenaka H, Ueda N, Ooboshi H, Opthof T, Kadomatsu K, Kodama I.

Cardiovasc Res. 2010 Apr 1;86(1):113-21. doi: 10.1093/cvr/cvp386. Epub 2009 Dec 7.


Left atrial pressure reduction for mitral stenosis reverses left atrial direction-dependent conduction abnormalities.

Coronel R, Langerveld J, Boersma LV, Wever EF, Bon L, van Dessel PF, Linnenbank AC, van Gilst WH, Ernst SM, Opthof T, van Hemel NM.

Cardiovasc Res. 2010 Mar 1;85(4):711-8. doi: 10.1093/cvr/cvp374. Epub 2009 Nov 25.


Is there a significant transmural gradient in repolarization time in the intact heart?: Repolarization Gradients in the Intact Heart.

Opthof T, Coronel R, Janse MJ.

Circ Arrhythm Electrophysiol. 2009 Feb;2(1):89-96. doi: 10.1161/CIRCEP.108.825356. No abstract available.


There is no transmural heterogeneity in an index of action potential duration in the canine left ventricle.

Voss F, Opthof T, Marker J, Bauer A, Katus HA, Becker R.

Heart Rhythm. 2009 Jul;6(7):1028-34. doi: 10.1016/j.hrthm.2009.03.028. Epub 2009 Mar 20.


Validation of a simple model for the morphology of the T wave in unipolar electrograms.

Potse M, Vinet A, Opthof T, Coronel R.

Am J Physiol Heart Circ Physiol. 2009 Aug;297(2):H792-801. doi: 10.1152/ajpheart.00064.2009. Epub 2009 May 22.


Dispersion of repolarization and arrhythmogenesis.

Coronel R, Wilms-Schopman FJ, Opthof T, Janse MJ.

Heart Rhythm. 2009 Apr;6(4):537-43. doi: 10.1016/j.hrthm.2009.01.013. Epub 2009 Jan 18.


Early termination of spiral wave reentry by combined blockade of Na+ and L-type Ca2+ currents in a perfused two-dimensional epicardial layer of rabbit ventricular myocardium.

Ishiguro YS, Honjo H, Opthof T, Okuno Y, Nakagawa H, Yamazaki M, Harada M, Takanari H, Suzuki T, Morishima M, Sakuma I, Kamiya K, Kodama I.

Heart Rhythm. 2009 May;6(5):684-92. doi: 10.1016/j.hrthm.2009.01.022. Epub 2009 Jan 21.


IK1 modulates the U-wave: insights in a 100-year-old enigma.

Postema PG, Ritsema van Eck HJ, Opthof T, van Herpen G, van Dessel PF, Priori SG, Wolpert C, Borggrefe M, Kors JA, Wilde AA.

Heart Rhythm. 2009 Mar;6(3):393-400. doi: 10.1016/j.hrthm.2008.11.024. Epub 2008 Nov 27. No abstract available.


Fraud and misconduct in science: the stem cell seduction: Implications for the peer-review process.

van der Heyden MA, van de Ven T, Opthof T.

Neth Heart J. 2009 Jan;17(1):25-9.

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