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Items: 1 to 50 of 200

1.

Comparative genomics of Leishmania (Mundinia).

Butenko A, Kostygov AY, Sádlová J, Kleschenko Y, Bečvář T, Podešvová L, Macedo DH, Žihala D, Lukeš J, Bates PA, Volf P, Opperdoes FR, Yurchenko V.

BMC Genomics. 2019 Oct 11;20(1):726. doi: 10.1186/s12864-019-6126-y.

2.

Lipids Are the Preferred Substrate of the Protist Naegleria gruberi, Relative of a Human Brain Pathogen.

Bexkens ML, Zimorski V, Sarink MJ, Wienk H, Brouwers JF, De Jonckheere JF, Martin WF, Opperdoes FR, van Hellemond JJ, Tielens AGM.

Cell Rep. 2018 Oct 16;25(3):537-543.e3. doi: 10.1016/j.celrep.2018.09.055.

3.

Recent advances in trypanosomatid research: genome organization, expression, metabolism, taxonomy and evolution.

Maslov DA, Opperdoes FR, Kostygov AY, Hashimi H, Lukeš J, Yurchenko V.

Parasitology. 2019 Jan;146(1):1-27. doi: 10.1017/S0031182018000951. Epub 2018 Jun 14.

4.

Leptomonas pyrrhocoris: Genomic insight into Parasite's Physiology.

Butenko A, Vieira TDS, Frolov AO, Opperdoes FR, Soares RP, Kostygov AY, Lukeš J, Yurchenko V.

Curr Genomics. 2018 Feb;19(2):150-156. doi: 10.2174/1389202918666170815143331. Review.

5.

Changes in the phosphoproteome of brown adipose tissue during hibernation in the ground squirrel, Ictidomys tridecemlineatus.

Herinckx G, Hussain N, Opperdoes FR, Storey KB, Rider MH, Vertommen D.

Physiol Genomics. 2017 Sep 1;49(9):462-472. doi: 10.1152/physiolgenomics.00038.2017. Epub 2017 Jul 10.

6.

Nonstructural Protein L* Species Specificity Supports a Mouse Origin for Vilyuisk Human Encephalitis Virus.

Drappier M, Opperdoes FR, Michiels T.

J Virol. 2017 Jun 26;91(14). pii: e00573-17. doi: 10.1128/JVI.00573-17. Print 2017 Jul 15.

7.

Molecular mechanisms of thermal resistance of the insect trypanosomatid Crithidia thermophila.

Ishemgulova A, Butenko A, Kortišová L, Boucinha C, Grybchuk-Ieremenko A, Morelli KA, Tesařová M, Kraeva N, Grybchuk D, Pánek T, Flegontov P, Lukeš J, Votýpka J, Pavan MG, Opperdoes FR, Spodareva V, d'Avila-Levy CM, Kostygov AY, Yurchenko V.

PLoS One. 2017 Mar 22;12(3):e0174165. doi: 10.1371/journal.pone.0174165. eCollection 2017.

8.

Genome of Leptomonas pyrrhocoris: a high-quality reference for monoxenous trypanosomatids and new insights into evolution of Leishmania.

Flegontov P, Butenko A, Firsov S, Kraeva N, Eliáš M, Field MC, Filatov D, Flegontova O, Gerasimov ES, Hlaváčová J, Ishemgulova A, Jackson AP, Kelly S, Kostygov AY, Logacheva MD, Maslov DA, Opperdoes FR, O'Reilly A, Sádlová J, Ševčíková T, Venkatesh D, Vlček Č, Volf P, Votýpka J, Záhonová K, Yurchenko V, Lukeš J.

Sci Rep. 2016 Mar 29;6:23704. doi: 10.1038/srep23704.

9.

Comparative Metabolism of Free-living Bodo saltans and Parasitic Trypanosomatids.

Opperdoes FR, Butenko A, Flegontov P, Yurchenko V, Lukeš J.

J Eukaryot Microbiol. 2016 Sep;63(5):657-78. doi: 10.1111/jeu.12315. Epub 2016 Apr 20. Review.

PMID:
27009761
10.

Leptomonas seymouri: Adaptations to the Dixenous Life Cycle Analyzed by Genome Sequencing, Transcriptome Profiling and Co-infection with Leishmania donovani.

Kraeva N, Butenko A, Hlaváčová J, Kostygov A, Myškova J, Grybchuk D, Leštinová T, Votýpka J, Volf P, Opperdoes F, Flegontov P, Lukeš J, Yurchenko V.

PLoS Pathog. 2015 Aug 28;11(8):e1005127. doi: 10.1371/journal.ppat.1005127. eCollection 2015 Aug.

11.

Understanding the functional difference between growth arrest-specific protein 6 and protein S: an evolutionary approach.

Studer RA, Opperdoes FR, Nicolaes GA, Mulder AB, Mulder R.

Open Biol. 2014 Oct;4(10). pii: 140121. doi: 10.1098/rsob.140121.

12.

TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei.

Shameer S, Logan-Klumpler FJ, Vinson F, Cottret L, Merlet B, Achcar F, Boshart M, Berriman M, Breitling R, Bringaud F, Bütikofer P, Cattanach AM, Bannerman-Chukualim B, Creek DJ, Crouch K, de Koning HP, Denise H, Ebikeme C, Fairlamb AH, Ferguson MA, Ginger ML, Hertz-Fowler C, Kerkhoven EJ, Mäser P, Michels PA, Nayak A, Nes DW, Nolan DP, Olsen C, Silva-Franco F, Smith TK, Taylor MC, Tielens AG, Urbaniak MD, van Hellemond JJ, Vincent IM, Wilkinson SR, Wyllie S, Opperdoes FR, Barrett MP, Jourdan F.

Nucleic Acids Res. 2015 Jan;43(Database issue):D637-44. doi: 10.1093/nar/gku944. Epub 2014 Oct 9.

13.

The streamlined genome of Phytomonas spp. relative to human pathogenic kinetoplastids reveals a parasite tailored for plants.

Porcel BM, Denoeud F, Opperdoes F, Noel B, Madoui MA, Hammarton TC, Field MC, Da Silva C, Couloux A, Poulain J, Katinka M, Jabbari K, Aury JM, Campbell DA, Cintron R, Dickens NJ, Docampo R, Sturm NR, Koumandou VL, Fabre S, Flegontov P, Lukeš J, Michaeli S, Mottram JC, Szöőr B, Zilberstein D, Bringaud F, Wincker P, Dollet M.

PLoS Genet. 2014 Feb 6;10(2):e1004007. doi: 10.1371/journal.pgen.1004007. eCollection 2014 Feb.

14.

Metabolic adaptations of Leishmania donovani in relation to differentiation, drug resistance, and drug pressure.

Berg M, Vanaerschot M, Jankevics A, Cuypers B, Maes I, Mukherjee S, Khanal B, Rijal S, Roy S, Opperdoes F, Breitling R, Dujardin JC.

Mol Microbiol. 2013 Oct;90(2):428-42. doi: 10.1111/mmi.12374. Epub 2013 Sep 11.

15.

Naegleria gruberi metabolism.

Opperdoes FR, De Jonckheere JF, Tielens AG.

Int J Parasitol. 2011 Aug 1;41(9):915-24. doi: 10.1016/j.ijpara.2011.04.004. Epub 2011 Jun 16. Review.

PMID:
21722646
16.

Comparative studies on the biochemical properties of the malic enzymes from Trypanosoma cruzi and Trypanosoma brucei.

Leroux AE, Maugeri DA, Opperdoes FR, Cazzulo JJ, Nowicki C.

FEMS Microbiol Lett. 2011 Jan;314(1):25-33. doi: 10.1111/j.1574-6968.2010.02142.x. Epub 2010 Nov 24.

17.

Oramoeba fumarolia gen. nov., sp. nov., a new marine heterolobosean amoeboflagellate growing at 54 °C.

De Jonckheere JF, Baumgartner M, Eberhardt S, Opperdoes FR, Stetter KO.

Eur J Protistol. 2011 Jan;47(1):16-23. doi: 10.1016/j.ejop.2010.09.002. Epub 2010 Oct 8.

PMID:
20932726
18.

Molecular identification of N-acetylaspartylglutamate synthase and beta-citrylglutamate synthase.

Collard F, Stroobant V, Lamosa P, Kapanda CN, Lambert DM, Muccioli GG, Poupaert JH, Opperdoes F, Van Schaftingen E.

J Biol Chem. 2010 Sep 24;285(39):29826-33. doi: 10.1074/jbc.M110.152629. Epub 2010 Jul 24.

19.

Molecular identification of NAT8 as the enzyme that acetylates cysteine S-conjugates to mercapturic acids.

Veiga-da-Cunha M, Tyteca D, Stroobant V, Courtoy PJ, Opperdoes FR, Van Schaftingen E.

J Biol Chem. 2010 Jun 11;285(24):18888-98. doi: 10.1074/jbc.M110.110924. Epub 2010 Apr 13.

20.

Evolution of vertebrate glucokinase regulatory protein from a bacterial N-acetylmuramate 6-phosphate etherase.

Veiga-da-Cunha M, Sokolova T, Opperdoes F, Van Schaftingen E.

Biochem J. 2009 Oct 12;423(3):323-32. doi: 10.1042/BJ20090986.

PMID:
19671048
21.

Marinamoeba thermophila, a new marine heterolobosean amoeba growing at 50 degrees C.

De Jonckheere JF, Baumgartner M, Opperdoes FR, Stetter KO.

Eur J Protistol. 2009 Aug;45(3):231-6. doi: 10.1016/j.ejop.2009.01.001. Epub 2009 Mar 31.

PMID:
19339165
22.

Biochemical characterization of stage-specific isoforms of aspartate aminotransferases from Trypanosoma cruzi and Trypanosoma brucei.

Marciano D, Llorente C, Maugeri DA, de la Fuente C, Opperdoes F, Cazzulo JJ, Nowicki C.

Mol Biochem Parasitol. 2008 Sep;161(1):12-20. doi: 10.1016/j.molbiopara.2008.05.005. Epub 2008 May 28.

PMID:
18602174
23.

Complex I of Trypanosomatidae: does it exist?

Opperdoes FR, Michels PA.

Trends Parasitol. 2008 Jul;24(7):310-7. doi: 10.1016/j.pt.2008.03.013. Epub 2008 Jun 3. Review.

PMID:
18534909
24.

Differential expression of glycosomal and mitochondrial proteins in the two major life-cycle stages of Trypanosoma brucei.

Vertommen D, Van Roy J, Szikora JP, Rider MH, Michels PA, Opperdoes FR.

Mol Biochem Parasitol. 2008 Apr;158(2):189-201. doi: 10.1016/j.molbiopara.2007.12.008. Epub 2007 Dec 23.

PMID:
18242729
25.

Retooling Leishmania metabolism: from sand fly gut to human macrophage.

Rosenzweig D, Smith D, Opperdoes F, Stern S, Olafson RW, Zilberstein D.

FASEB J. 2008 Feb;22(2):590-602. Epub 2007 Sep 20.

PMID:
17884972
26.

Horizontal gene transfer in trypanosomatids.

Opperdoes FR, Michels PA.

Trends Parasitol. 2007 Oct;23(10):470-6. Epub 2007 Sep 7.

PMID:
17826337
27.

Antitrypanosomal activity of triterpenoids and sterols from the leaves of Strychnos spinosa and related compounds.

Hoet S, Pieters L, Muccioli GG, Habib-Jiwan JL, Opperdoes FR, Quetin-Leclercq J.

J Nat Prod. 2007 Aug;70(8):1360-3. Epub 2007 Jul 19.

PMID:
17637068
28.

Metabolism of Leishmania: proven and predicted.

Opperdoes FR, Coombs GH.

Trends Parasitol. 2007 Apr;23(4):149-58. Epub 2007 Feb 22. Review.

PMID:
17320480
29.

In silico prediction of the glycosomal enzymes of Leishmania major and trypanosomes.

Opperdoes FR, Szikora JP.

Mol Biochem Parasitol. 2006 Jun;147(2):193-206. Epub 2006 Mar 9.

PMID:
16546274
30.

The presence of four iron-containing superoxide dismutase isozymes in trypanosomatidae: characterization, subcellular localization, and phylogenetic origin in Trypanosoma brucei.

Dufernez F, Yernaux C, Gerbod D, Noël C, Chauvenet M, Wintjens R, Edgcomb VP, Capron M, Opperdoes FR, Viscogliosi E.

Free Radic Biol Med. 2006 Jan 15;40(2):210-25. Epub 2005 Aug 11.

PMID:
16413404
31.

The malate dehydrogenase isoforms from Trypanosoma brucei: subcellular localization and differential expression in bloodstream and procyclic forms.

Aranda A, Maugeri D, Uttaro AD, Opperdoes F, Cazzulo JJ, Nowicki C.

Int J Parasitol. 2006 Mar;36(3):295-307. Epub 2005 Oct 21.

PMID:
16321390
32.

The extraordinary mitochondrion and unusual citric acid cycle in Trypanosoma brucei.

van Hellemond JJ, Opperdoes FR, Tielens AG.

Biochem Soc Trans. 2005 Nov;33(Pt 5):967-71. Review.

PMID:
16246022
33.

The Trypanosoma cruzi proteome.

Atwood JA 3rd, Weatherly DB, Minning TA, Bundy B, Cavola C, Opperdoes FR, Orlando R, Tarleton RL.

Science. 2005 Jul 15;309(5733):473-6.

34.

The genome of the African trypanosome Trypanosoma brucei.

Berriman M, Ghedin E, Hertz-Fowler C, Blandin G, Renauld H, Bartholomeu DC, Lennard NJ, Caler E, Hamlin NE, Haas B, Böhme U, Hannick L, Aslett MA, Shallom J, Marcello L, Hou L, Wickstead B, Alsmark UC, Arrowsmith C, Atkin RJ, Barron AJ, Bringaud F, Brooks K, Carrington M, Cherevach I, Chillingworth TJ, Churcher C, Clark LN, Corton CH, Cronin A, Davies RM, Doggett J, Djikeng A, Feldblyum T, Field MC, Fraser A, Goodhead I, Hance Z, Harper D, Harris BR, Hauser H, Hostetler J, Ivens A, Jagels K, Johnson D, Johnson J, Jones K, Kerhornou AX, Koo H, Larke N, Landfear S, Larkin C, Leech V, Line A, Lord A, Macleod A, Mooney PJ, Moule S, Martin DM, Morgan GW, Mungall K, Norbertczak H, Ormond D, Pai G, Peacock CS, Peterson J, Quail MA, Rabbinowitsch E, Rajandream MA, Reitter C, Salzberg SL, Sanders M, Schobel S, Sharp S, Simmonds M, Simpson AJ, Tallon L, Turner CM, Tait A, Tivey AR, Van Aken S, Walker D, Wanless D, Wang S, White B, White O, Whitehead S, Woodward J, Wortman J, Adams MD, Embley TM, Gull K, Ullu E, Barry JD, Fairlamb AH, Opperdoes F, Barrell BG, Donelson JE, Hall N, Fraser CM, Melville SE, El-Sayed NM.

Science. 2005 Jul 15;309(5733):416-22.

35.
36.

Experimental and in silico analyses of glycolytic flux control in bloodstream form Trypanosoma brucei.

Albert MA, Haanstra JR, Hannaert V, Van Roy J, Opperdoes FR, Bakker BM, Michels PA.

J Biol Chem. 2005 Aug 5;280(31):28306-15. Epub 2005 Jun 14.

37.

New functions for parts of the Krebs cycle in procyclic Trypanosoma brucei, a cycle not operating as a cycle.

van Weelden SW, van Hellemond JJ, Opperdoes FR, Tielens AG.

J Biol Chem. 2005 Apr 1;280(13):12451-60. Epub 2005 Jan 12.

38.

Tissue distribution and evolution of fructosamine 3-kinase and fructosamine 3-kinase-related protein.

Delplanque J, Delpierre G, Opperdoes FR, Van Schaftingen E.

J Biol Chem. 2004 Nov 5;279(45):46606-13. Epub 2004 Aug 25.

39.

Natural products active against African trypanosomes: a step towards new drugs.

Hoet S, Opperdoes F, Brun R, Quetin-Leclercq J.

Nat Prod Rep. 2004 Jun;21(3):353-64. Epub 2004 May 5. Review.

PMID:
15162223
40.

Alkaloids from Cassytha filiformis and related aporphines: antitrypanosomal activity, cytotoxicity, and interaction with DNA and topoisomerases.

Hoet S, Stévigny C, Block S, Opperdoes F, Colson P, Baldeyrou B, Lansiaux A, Bailly C, Quetin-Leclercq J.

Planta Med. 2004 May;70(5):407-13.

PMID:
15124084
42.

Interaction of substituted hexose analogues with the Trypanosoma brucei hexose transporter.

Azema L, Claustre S, Alric I, Blonski C, Willson M, Perié J, Baltz T, Tetaud E, Bringaud F, Cottem D, Opperdoes FR, Barrett MP.

Biochem Pharmacol. 2004 Feb 1;67(3):459-67.

PMID:
15037198
43.

In vitro antitrypanosomal activity of ethnopharmacologically selected Beninese plants.

Hoet S, Opperdoes F, Brun R, Adjakidjé V, Quetin-Leclercq J.

J Ethnopharmacol. 2004 Mar;91(1):37-42.

PMID:
15036465
44.

Evolution of energy metabolism and its compartmentation in Kinetoplastida.

Hannaert V, Bringaud F, Opperdoes FR, Michels PA.

Kinetoplastid Biol Dis. 2003 Oct 28;2(1):11.

45.

Kinetic characterization, structure modelling studies and crystallization of Trypanosoma brucei enolase.

Hannaert V, Albert MA, Rigden DJ, da Silva Giotto MT, Thiemann O, Garratt RC, Van Roy J, Opperdoes FR, Michels PA.

Eur J Biochem. 2003 Aug;270(15):3205-13.

46.

The multifunctional isopropyl alcohol dehydrogenase of Phytomonas sp. could be the result of a horizontal gene transfer from a bacterium to the trypanosomatid lineage.

Molinas SM, Altabe SG, Opperdoes FR, Rider MH, Michels PA, Uttaro AD.

J Biol Chem. 2003 Sep 19;278(38):36169-75. Epub 2003 Jul 9.

47.

Plant-like traits associated with metabolism of Trypanosoma parasites.

Hannaert V, Saavedra E, Duffieux F, Szikora JP, Rigden DJ, Michels PA, Opperdoes FR.

Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1067-71. Epub 2003 Jan 27.

48.

Characterization of the ysa pathogenicity locus in the chromosome of Yersinia enterocolitica and phylogeny analysis of type III secretion systems.

Foultier B, Troisfontaines P, Müller S, Opperdoes FR, Cornelis GR.

J Mol Evol. 2002 Jul;55(1):37-51.

PMID:
12165841
49.

Sequencing, modeling, and selective inhibition of Trypanosoma brucei hexokinase.

Willson M, Sanejouand YH, Perie J, Hannaert V, Opperdoes F.

Chem Biol. 2002 Jul;9(7):839-47.

50.

The putative effector-binding site of Leishmania mexicana pyruvate kinase studied by site-directed mutagenesis.

Hannaert V, Yernaux C, Rigden DJ, Fothergill-Gilmore LA, Opperdoes FR, Michels PA.

FEBS Lett. 2002 Mar 13;514(2-3):255-9.

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