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Items: 1 to 50 of 62

1.

Decreased CSF Levels of ß-Amyloid in Patients With Cortical Superficial Siderosis.

Catak C, Zedde M, Malik R, Janowitz D, Soric V, Seegerer A, Krebs A, Düring M, Opherk C, Linn J, Wollenweber FA.

Front Neurol. 2019 Apr 26;10:439. doi: 10.3389/fneur.2019.00439. eCollection 2019.

2.

Prognostic relevance of cortical superficial siderosis in cerebral amyloid angiopathy.

Wollenweber FA, Opherk C, Zedde M, Catak C, Malik R, Duering M, Konieczny MJ, Pascarella R, Samões R, Correia M, Martí-Fàbregas J, Linn J, Dichgans M.

Neurology. 2019 Feb 19;92(8):e792-e801. doi: 10.1212/WNL.0000000000006956. Epub 2019 Jan 23.

PMID:
30674596
3.

Correction: The effect of NOTCH3 pathogenic variant position on CADASIL disease severity: NOTCH3 EGFr 1-6 pathogenic variant are associated with a more severe phenotype and lower survival compared with EGFr 7-34 pathogenic variant.

Rutten JW, Van Eijsden BJ, Duering M, Jouvent E, Opherk C, Pantoni L, Federico A, Dichgans M, Markus HS, Chabriat H, Oberstein SAJL.

Genet Med. 2018 Sep 20. doi: 10.1038/s41436-018-0306-z. [Epub ahead of print]

4.

The effect of NOTCH3 pathogenic variant position on CADASIL disease severity: NOTCH3 EGFr 1-6 pathogenic variant are associated with a more severe phenotype and lower survival compared with EGFr 7-34 pathogenic variant.

Rutten JW, Van Eijsden BJ, Duering M, Jouvent E, Opherk C, Pantoni L, Federico A, Dichgans M, Markus HS, Chabriat H, Lesnik Oberstein SAJ.

Genet Med. 2019 Mar;21(3):676-682. doi: 10.1038/s41436-018-0088-3. Epub 2018 Jul 22. Erratum in: Genet Med. 2018 Sep 20;:.

PMID:
30032161
5.

Cortical Superficial Siderosis in Different Types of Cerebral Small Vessel Disease.

Wollenweber FA, Baykara E, Zedde M, Gesierich B, Achmüller M, Jouvent E, Viswanathan A, Ropele S, Chabriat H, Schmidt R, Opherk C, Dichgans M, Linn J, Duering M.

Stroke. 2017 May;48(5):1404-1407. doi: 10.1161/STROKEAHA.117.016833. Epub 2017 Mar 31.

PMID:
28364025
6.

Prevalence and characteristics of migraine in CADASIL.

Guey S, Mawet J, Hervé D, Duering M, Godin O, Jouvent E, Opherk C, Alili N, Dichgans M, Chabriat H.

Cephalalgia. 2016 Oct;36(11):1038-1047. doi: 10.1177/0333102415620909. Epub 2016 Jul 11.

PMID:
26646784
7.

Predictors of Clinical Worsening in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy: Prospective Cohort Study.

Chabriat H, Hervé D, Duering M, Godin O, Jouvent E, Opherk C, Alili N, Reyes S, Jabouley A, Zieren N, Guichard JP, Pachai C, Vicaut E, Dichgans M.

Stroke. 2016 Jan;47(1):4-11. doi: 10.1161/STROKEAHA.115.010696. Epub 2015 Nov 17.

PMID:
26578659
8.

Cortical superficial siderosis: detection and clinical significance in cerebral amyloid angiopathy and related conditions.

Charidimou A, Linn J, Vernooij MW, Opherk C, Akoudad S, Baron JC, Greenberg SM, Jäger HR, Werring DJ.

Brain. 2015 Aug;138(Pt 8):2126-39. doi: 10.1093/brain/awv162. Epub 2015 Jun 26. Review.

PMID:
26115675
9.

APOE ɛ2 is associated with white matter hyperintensity volume in CADASIL.

Gesierich B, Opherk C, Rosand J, Gonik M, Malik R, Jouvent E, Hervé D, Adib-Samii P, Bevan S, Pianese L, Silvestri S, Dotti MT, De Stefano N, van der Grond J, Boon EM, Pescini F, Rost N, Pantoni L, Oberstein SA, Federico A, Ragno M, Markus HS, Tournier-Lasserve E, Chabriat H, Dichgans M, Duering M, Ewers M.

J Cereb Blood Flow Metab. 2016 Jan;36(1):199-203.

10.

Clinical spectrum, underlying etiologies and radiological characteristics of cortical superficial siderosis.

Lummel N, Wollenweber FA, Demaerel P, Bochmann K, Malik R, Opherk C, Linn J.

J Neurol. 2015 Jun;262(6):1455-62. doi: 10.1007/s00415-015-7736-1. Epub 2015 Apr 11.

PMID:
25860345
11.

Cysteine-sparing CADASIL mutations in NOTCH3 show proaggregatory properties in vitro.

Wollenweber FA, Hanecker P, Bayer-Karpinska A, Malik R, Bäzner H, Moreton F, Muir KW, Müller S, Giese A, Opherk C, Dichgans M, Haffner C, Duering M.

Stroke. 2015 Mar;46(3):786-92. doi: 10.1161/STROKEAHA.114.007472. Epub 2015 Jan 20.

PMID:
25604251
12.

Sequestration of latent TGF-β binding protein 1 into CADASIL-related Notch3-ECD deposits.

Kast J, Hanecker P, Beaufort N, Giese A, Joutel A, Dichgans M, Opherk C, Haffner C.

Acta Neuropathol Commun. 2014 Aug 13;2:96. doi: 10.1186/s40478-014-0096-8.

13.

Penumbra pattern assessment in acute stroke patients: comparison of quantitative and non-quantitative methods in whole brain CT perfusion.

Thierfelder KM, von Baumgarten L, Baumann AB, Meinel FG, Helck AD, Opherk C, Straube A, Reiser MF, Sommer WH.

PLoS One. 2014 Aug 21;9(8):e105413. doi: 10.1371/journal.pone.0105413. eCollection 2014.

14.

Vertebral artery hypoplasia: frequency and effect on cerebellar blood flow characteristics.

Thierfelder KM, Baumann AB, Sommer WH, Armbruster M, Opherk C, Janssen H, Reiser MF, Straube A, von Baumgarten L.

Stroke. 2014 May;45(5):1363-8. doi: 10.1161/STROKEAHA.113.004188. Epub 2014 Apr 3.

PMID:
24699051
15.

Genome-wide genotyping demonstrates a polygenic risk score associated with white matter hyperintensity volume in CADASIL.

Opherk C, Gonik M, Duering M, Malik R, Jouvent E, Hervé D, Adib-Samii P, Bevan S, Pianese L, Silvestri S, Dotti MT, De Stefano N, Liem M, Boon EM, Pescini F, Pachai C, Bracoud L, Müller-Myhsok B, Meitinger T, Rost N, Pantoni L, Lesnik Oberstein S, Federico A, Ragno M, Markus HS, Tournier-Lasserve E, Rosand J, Chabriat H, Dichgans M.

Stroke. 2014 Apr;45(4):968-72. doi: 10.1161/STROKEAHA.113.004461. Epub 2014 Feb 27.

PMID:
24578207
16.

Diagnostic accuracy of whole-brain computed tomographic perfusion imaging in small-volume infarctions.

Thierfelder KM, von Baumgarten L, Löchelt AC, Meinel FG, Armbruster M, Beyer SE, Patzig M, Opherk C, Reiser MF, Sommer WH.

Invest Radiol. 2014 Apr;49(4):236-42. doi: 10.1097/RLI.0000000000000023.

PMID:
24500091
17.

The carotid plaque imaging in acute stroke (CAPIAS) study: protocol and initial baseline data.

Bayer-Karpinska A, Schwarz F, Wollenweber FA, Poppert H, Boeckh-Behrens T, Becker A, Clevert DA, Nikolaou K, Opherk C, Dichgans M, Saam T.

BMC Neurol. 2013 Dec 13;13:201. doi: 10.1186/1471-2377-13-201.

18.

Prevalence of cortical superficial siderosis in patients with cognitive impairment.

Wollenweber FA, Buerger K, Mueller C, Ertl-Wagner B, Malik R, Dichgans M, Linn J, Opherk C.

J Neurol. 2014 Feb;261(2):277-82. doi: 10.1007/s00415-013-7181-y. Epub 2013 Nov 13.

PMID:
24221645
19.

Doppelte Plättchenhemmung als Sekundärprävention nach lakunärer zerebraler Ischämie – nicht effektiver als ASS alleine.

Opherk C.

Fortschr Neurol Psychiatr. 2013 Jun;81(6):306. German. No abstract available.

PMID:
23936923
20.

Hyperattenuated intracerebral lesions after mechanical recanalization in acute stroke.

Lummel N, Schulte-Altedorneburg G, Bernau C, Pfefferkorn T, Patzig M, Janssen H, Opherk C, Brückmann H, Linn J.

AJNR Am J Neuroradiol. 2014 Feb;35(2):345-51. doi: 10.3174/ajnr.A3656. Epub 2013 Aug 1.

21.

The Determinants of Dementia After Stroke (DEDEMAS) Study: protocol and pilot data.

Wollenweber FA, Zietemann V, Rominger A, Opherk C, Bayer-Karpinska A, Gschwendtner A, Coloma Andrews L, Bürger K, Duering M, Dichgans M.

Int J Stroke. 2014 Apr;9(3):387-92. doi: 10.1111/ijs.12092. Epub 2013 Jul 9.

PMID:
23834337
22.

Serial carotid MRI identifies rupture of a vulnerable plaque resulting in amaurosis fugax.

Schwarz F, Bayer-Karpinska A, Poppert H, Buchholz M, Cyran C, Grimm J, Helck A, Nikolaou K, Opherk C, Dichgans M, Saam T.

Neurology. 2013 Mar 19;80(12):1171-2. doi: 10.1212/WNL.0b013e31828869ad. No abstract available.

PMID:
23509049
23.

Subclinical hyperthyroidism is a risk factor for poor functional outcome after ischemic stroke.

Wollenweber FA, Zietemann V, Gschwendtner A, Opherk C, Dichgans M.

Stroke. 2013 May;44(5):1446-8. doi: 10.1161/STROKEAHA.113.000833. Epub 2013 Mar 12.

PMID:
23482604
24.

Reversible cerebral vasoconstriction syndrome with concurrent bilateral carotid artery dissection.

Bayer-Karpinska A, Patzig M, Adamczyk C, Dimitriadis K, Wollenweber FA, Dichgans M, Jahn K, Opherk C.

Cephalalgia. 2013 May;33(7):491-5. doi: 10.1177/0333102413479836. Epub 2013 Mar 8.

PMID:
23475293
25.

Extensive white matter hyperintensities may increase brain volume in cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy.

Yao M, Jouvent E, During M, Godin O, Hervé D, Guichard JP, Zhu YC, Gschwendtner A, Opherk C, Dichgans M, Chabriat H.

Stroke. 2012 Dec;43(12):3252-7. doi: 10.1161/STROKEAHA.112.664854.

PMID:
23185048
26.

Identification of a strategic brain network underlying processing speed deficits in vascular cognitive impairment.

Duering M, Gonik M, Malik R, Zieren N, Reyes S, Jouvent E, Hervé D, Gschwendtner A, Opherk C, Chabriat H, Dichgans M.

Neuroimage. 2013 Feb 1;66:177-83. doi: 10.1016/j.neuroimage.2012.10.084. Epub 2012 Nov 13.

PMID:
23153965
27.

A young man with symptomatic epilepsy and right hemianopia: family affair.

von Baumgarten L, Pfeifenbring S, Terpolilli N, Schüller U, Jahn K, Opherk C, Freilinger T.

Neurology. 2012 Nov 6;79(19):2008-9. doi: 10.1212/WNL.0b013e3182735c68. No abstract available.

PMID:
23128442
28.

Black blood MRI in suspected large artery primary angiitis of the central nervous system.

Pfefferkorn T, Linn J, Habs M, Opherk C, Cyran C, Ottomeyer C, Straube A, Dichgans M, Nikolaou K, Saam T.

J Neuroimaging. 2013 Jul;23(3):379-83. doi: 10.1111/j.1552-6569.2012.00743.x. Epub 2012 Aug 28.

PMID:
22928809
29.

Superficial siderosis is a warning sign for future intracranial hemorrhage.

Linn J, Wollenweber FA, Lummel N, Bochmann K, Pfefferkorn T, Gschwendtner A, Bruckmann H, Dichgans M, Opherk C.

J Neurol. 2013 Jan;260(1):176-81. doi: 10.1007/s00415-012-6610-7. Epub 2012 Jul 22.

PMID:
22820723
30.

Education modifies the relation of vascular pathology to cognitive function: cognitive reserve in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.

Zieren N, Duering M, Peters N, Reyes S, Jouvent E, Hervé D, Gschwendtner A, Mewald Y, Opherk C, Chabriat H, Dichgans M.

Neurobiol Aging. 2013 Feb;34(2):400-7. doi: 10.1016/j.neurobiolaging.2012.04.019. Epub 2012 May 23.

PMID:
22626524
31.

Multimodal recanalization therapy in acute basilar artery occlusion: long-term functional outcome and quality of life.

Ottomeyer C, Zeller J, Fesl G, Holtmannspötter M, Opherk C, Bender A, Dichgans M, Brückmann H, Pfefferkorn T.

Stroke. 2012 Aug;43(8):2130-5. doi: 10.1161/STROKEAHA.112.651281. Epub 2012 May 8.

PMID:
22569932
32.

Endovascular mechanical recanalisation after intravenous thrombolysis in acute anterior circulation stroke: the impact of a new temporary stent.

Fesl G, Patzig M, Holtmannspoetter M, Mayer TE, Pfefferkorn T, Opherk C, Brueckmann H, Wiesmann M.

Cardiovasc Intervent Radiol. 2012 Dec;35(6):1326-31. doi: 10.1007/s00270-011-0317-5. Epub 2011 Dec 9.

PMID:
22160095
33.

Age determination of vessel wall hematoma in spontaneous cervical artery dissection: a multi-sequence 3T cardiovascular magnetic resonance study.

Habs M, Pfefferkorn T, Cyran CC, Grimm J, Rominger A, Hacker M, Opherk C, Reiser MF, Nikolaou K, Saam T.

J Cardiovasc Magn Reson. 2011 Nov 28;13:76. doi: 10.1186/1532-429X-13-76.

34.

Effects of gender on the phenotype of CADASIL.

Gunda B, Hervé D, Godin O, Bruno M, Reyes S, Alili N, Opherk C, Jouvent E, Düring M, Bousser MG, Dichgans M, Chabriat H.

Stroke. 2012 Jan;43(1):137-41. doi: 10.1161/STROKEAHA.111.631028. Epub 2011 Oct 27.

PMID:
22033996
35.

Preceding intravenous thrombolysis facilitates endovascular mechanical recanalization in large intracranial artery occlusion.

Pfefferkorn T, Holtmannspötter M, Patzig M, Brückmann H, Ottomeyer C, Opherk C, Dichgans M, Fesl G.

Int J Stroke. 2012 Jan;7(1):14-8. doi: 10.1111/j.1747-4949.2011.00639.x. Epub 2011 Oct 20.

PMID:
22010996
36.

Strategic role of frontal white matter tracts in vascular cognitive impairment: a voxel-based lesion-symptom mapping study in CADASIL.

Duering M, Zieren N, Hervé D, Jouvent E, Reyes S, Peters N, Pachai C, Opherk C, Chabriat H, Dichgans M.

Brain. 2011 Aug;134(Pt 8):2366-75. doi: 10.1093/brain/awr169. Epub 2011 Jul 14.

PMID:
21764819
37.

Co-aggregate formation of CADASIL-mutant NOTCH3: a single-particle analysis.

Duering M, Karpinska A, Rosner S, Hopfner F, Zechmeister M, Peters N, Kremmer E, Haffner C, Giese A, Dichgans M, Opherk C.

Hum Mol Genet. 2011 Aug 15;20(16):3256-65. doi: 10.1093/hmg/ddr237. Epub 2011 May 30.

PMID:
21628316
38.

Verbal memory impairment in subcortical ischemic vascular disease: a descriptive analysis in CADASIL.

Epelbaum S, Benisty S, Reyes S, O'Sullivan M, Jouvent E, Düring M, Hervé D, Opherk C, Hernandez K, Kurtz A, Viswanathan A, Bousser MG, Dichgans M, Chabriat H.

Neurobiol Aging. 2011 Dec;32(12):2172-82. doi: 10.1016/j.neurobiolaging.2009.12.018. Epub 2010 Feb 9.

PMID:
20149485
39.

[Vasculitis and hereditary small vessel diseases].

Opherk C, Peters N, Dichgans M.

Internist (Berl). 2009 Nov;50(11):1200-9. doi: 10.1007/s00108-009-2469-9. German.

PMID:
19838657
40.

CADASIL mutations enhance spontaneous multimerization of NOTCH3.

Opherk C, Duering M, Peters N, Karpinska A, Rosner S, Schneider E, Bader B, Giese A, Dichgans M.

Hum Mol Genet. 2009 Aug 1;18(15):2761-7. doi: 10.1093/hmg/ddp211. Epub 2009 May 5.

PMID:
19417009
41.

Malignant hemispheric infarction in Takayasu arteritis.

Pfefferkorn T, Bitterling H, Hüfner K, Opherk C, Schewe S, Pfister HW, Straube A, Dichgans M.

J Neurol. 2008 Sep;255(9):1425-6. doi: 10.1007/s00415-008-0932-5. Epub 2008 Jun 27. No abstract available.

PMID:
18574616
42.

Enhanced L-arginine-induced vasoreactivity suggests endothelial dysfunction in CADASIL.

Peters N, Freilinger T, Opherk C, Pfefferkorn T, Dichgans M.

J Neurol. 2008 Aug;255(8):1203-8. doi: 10.1007/s00415-008-0876-9. Epub 2008 Jun 13.

PMID:
18537053
43.

Staged escalation therapy in acute basilar artery occlusion: intravenous thrombolysis and on-demand consecutive endovascular mechanical thrombectomy: preliminary experience in 16 patients.

Pfefferkorn T, Mayer TE, Opherk C, Peters N, Straube A, Pfister HW, Holtmannspötter M, Müller-Schunk S, Wiesmann M, Dichgans M.

Stroke. 2008 May;39(5):1496-500. doi: 10.1161/STROKEAHA.107.505123. Epub 2008 Mar 6.

PMID:
18323481
44.

Effects of short term atorvastatin treatment on cerebral hemodynamics in CADASIL.

Peters N, Freilinger T, Opherk C, Pfefferkorn T, Dichgans M.

J Neurol Sci. 2007 Sep 15;260(1-2):100-5. Epub 2007 May 24.

PMID:
17531269
45.

Heritability of MRI lesion volume in CADASIL: evidence for genetic modifiers.

Opherk C, Peters N, Holtmannspötter M, Gschwendtner A, Müller-Myhsok B, Dichgans M.

Stroke. 2006 Nov;37(11):2684-9. Epub 2006 Sep 28.

PMID:
17008614
46.

Brain volume changes in CADASIL: a serial MRI study in pure subcortical ischemic vascular disease.

Peters N, Holtmannspötter M, Opherk C, Gschwendtner A, Herzog J, Sämann P, Dichgans M.

Neurology. 2006 May 23;66(10):1517-22.

PMID:
16717211
47.

Successful bilateral pallidal stimulation for Meige syndrome and spasmodic torticollis.

Opherk C, Gruber C, Steude U, Dichgans M, Bötzel K.

Neurology. 2006 Feb 28;66(4):E14. No abstract available.

PMID:
16505291
48.

Diffusion magnetic resonance histograms as a surrogate marker and predictor of disease progression in CADASIL: a two-year follow-up study.

Holtmannspötter M, Peters N, Opherk C, Martin D, Herzog J, Brückmann H, Sämann P, Gschwendtner A, Dichgans M.

Stroke. 2005 Dec;36(12):2559-65. Epub 2005 Nov 3.

PMID:
16269644
49.

The pattern of cognitive performance in CADASIL: a monogenic condition leading to subcortical ischemic vascular dementia.

Peters N, Opherk C, Danek A, Ballard C, Herzog J, Dichgans M.

Am J Psychiatry. 2005 Nov;162(11):2078-85.

PMID:
16263847
50.

Spectrum of mutations in biopsy-proven CADASIL: implications for diagnostic strategies.

Peters N, Opherk C, Bergmann T, Castro M, Herzog J, Dichgans M.

Arch Neurol. 2005 Jul;62(7):1091-4.

PMID:
16009764

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