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Items: 38

1.

Increased delivery of chemotherapy to the vitreous by inhibition of the blood-retinal barrier.

Pascual-Pasto G, Olaciregui NG, Opezzo JAW, Castillo-Ecija H, Cuadrado-Vilanova M, Paco S, Rivero EM, Vila-Ubach M, Restrepo-Perdomo CA, Torrebadell M, Suñol M, Schaiquevich P, Mora J, Bramuglia GF, Chantada GL, Carcaboso AM.

J Control Release. 2017 Oct 28;264:34-44. doi: 10.1016/j.jconrel.2017.08.018. Epub 2017 Aug 19.

PMID:
28830790
2.

Intranasal administration of antiretroviral-loaded micelles for anatomical targeting to the brain in HIV.

Chiappetta DA, Hocht C, Opezzo JA, Sosnik A.

Nanomedicine (Lond). 2013 Feb;8(2):223-37. doi: 10.2217/nnm.12.104. Epub 2012 Nov 22.

PMID:
23173734
3.

Cardiovascular drugs inducing QT prolongation: facts and evidence.

Taira CA, Opezzo JA, Mayer MA, Höcht C.

Curr Drug Saf. 2010 Jan;5(1):65-72. Review.

PMID:
20210721
4.

Episcleral implants for topotecan delivery to the posterior segment of the eye.

Carcaboso AM, Chiappetta DA, Opezzo JA, Höcht C, Fandiño AC, Croxatto JO, Rubio MC, Sosnik A, Abramson DH, Bramuglia GF, Chantada GL.

Invest Ophthalmol Vis Sci. 2010 Apr;51(4):2126-34. doi: 10.1167/iovs.09-4050. Epub 2009 Oct 15.

PMID:
19834044
5.

Differential hippocampal pharmacokinetics of phenobarbital and carbamazepine in repetitive seizures induced by 3-mercaptopropionic acid.

Höcht C, Lazarowski A, Gonzalez NN, Mayer MA, Opezzo JA, Taira CA, Girardi E.

Neurosci Lett. 2009 Mar 27;453(1):54-7. doi: 10.1016/j.neulet.2009.01.079. Epub 2009 Feb 4.

PMID:
19429015
6.

Increased sensitivity to diltiazem hypotensive effect in an experimental model of high-renin hypertension.

Bertera FM, Mayer MA, Opezzo JA, Taira CA, Höcht C.

J Pharm Pharmacol. 2009 Jan;61(1):79-87. doi: 10.1211/jpp/61.01.0011.

PMID:
19126300
7.

Therapeutic implications of beta-adrenergic receptor pharmacodynamic properties.

Taira CA, Carranza A, Mayer M, Di Verniero C, Opezzo JA, Höcht C.

Curr Clin Pharmacol. 2008 Sep;3(3):174-84. Review.

PMID:
18781904
8.

Application of microdialysis in clinical pharmacology.

Höcht C, Opezzo JA, Bramuglia GF, Taira CA.

Curr Clin Pharmacol. 2006 May;1(2):163-83. Review.

PMID:
18666369
9.

In vitro and in vivo pharmacodynamic properties of metoprolol in fructose-fed hypertensive rats.

Di Verniero CA, Silberman EA, Mayer MA, Opezzo JA, Taira CA, Höcht C.

J Cardiovasc Pharmacol. 2008 Jun;51(6):532-41. doi: 10.1097/FJC.0b013e3181730306.

PMID:
18475202
10.

Comparison of different pharmacodynamic models for PK-PD modeling of verapamil in renovascular hypertension.

Bertera FM, Mayer MA, Opezzo JA, Taira CA, Höcht C.

J Pharmacol Toxicol Methods. 2008 May-Jun;57(3):212-9. doi: 10.1016/j.vascn.2008.03.002. Epub 2008 Mar 19.

PMID:
18442930
11.

Relative bioavailability of new formulation of paracetamol effervescent powder containing sodium bicarbonate versus paracetamol tablets: a comparative pharmacokinetic study in fed subjects.

Di Girolamo G, Opezzo JA, Lopez MI, Schere D, Keller G, Gonzalez CD, Massa JM, de los Santos MC.

Expert Opin Pharmacother. 2007 Oct;8(15):2449-57.

PMID:
17931082
12.

Hypothalamic angiotensinergic-noradrenergic systems interaction in fructose induced hypertension.

Mayer MA, Höcht C, Gironacci M, Opezzo JA, Taira CA, Fernández BE, Puyó AM.

Regul Pept. 2008 Feb 7;146(1-3):38-45. Epub 2007 Jul 29.

PMID:
17822786
13.

High fructose diet increases anterior hypothalamic alpha 2-adrenoceptors responsiveness.

Mayer MA, Höcht C, Opezzo JA, Taira CA, Fernández BE, Puyó AM.

Neurosci Lett. 2007 Aug 16;423(2):128-32. Epub 2007 Aug 1.

PMID:
17683864
14.

Parent drug and/or metabolite? Which of them is most appropriate to establish bioequivalence of two oral oxcarbazepine formulations in healthy volunteers?

Di Girolamo G, Opezzo JA, Schere D, Gonzalez CD, Moncalvo JJ.

Expert Opin Pharmacother. 2007 Jul;8(10):1415-23.

PMID:
17661724
15.

Pharmacokinetic-pharmacodynamic modeling of diltiazem in spontaneously hypertensive rats: a microdialysis study.

Bertera FM, Mayer MA, Opezzo JA, Taira CA, Bramuglia GF, Höcht C.

J Pharmacol Toxicol Methods. 2007 Nov-Dec;56(3):290-9. Epub 2007 May 4.

PMID:
17560132
16.

Changes in the in vitro pharmacodynamic properties of metoprolol in atria isolated from spontaneously hypertensive rats.

Di Verniero C, Höcht C, Opezzo JA, Taira CA.

Clin Exp Pharmacol Physiol. 2007 Mar;34(3):161-5.

PMID:
17250633
17.

Nimodipine restores the altered hippocampal phenytoin pharmacokinetics in a refractory epileptic model.

Höcht C, Lazarowski A, Gonzalez NN, Auzmendi J, Opezzo JA, Bramuglia GF, Taira CA, Girardi E.

Neurosci Lett. 2007 Feb 14;413(2):168-72. Epub 2007 Jan 8.

PMID:
17240061
18.

Role of hypothalamic alpha-adrenoceptor activity in fructose-induced hypertension.

Mayer MA, Höcht C, Opezzo JA, Peredo HA, Navacchia D, Taira CA, Fernández BE, Puyó AM.

Clin Exp Pharmacol Physiol. 2006 Oct;33(10):904-9.

PMID:
17002666
19.

Application of microdialysis for pharmacokinetic-pharmacodynamic modelling.

Höcht C, Opezzo JA, Bramuglia GF, Taira CA.

Expert Opin Drug Discov. 2006 Sep;1(4):289-301. doi: 10.1517/17460441.1.4.289.

PMID:
23495900
20.

Pharmacokinetic-pharmacodynamic (PK-PD) modeling of cardiovascular effects of metoprolol in spontaneously hypertensive rats: a microdialysis study.

Höcht C, Di Verniero C, Opezzo JA, Bramuglia GF, Taira CA.

Naunyn Schmiedebergs Arch Pharmacol. 2006 Jul;373(4):310-8. Epub 2006 May 30.

PMID:
16733693
21.

Hypothalamic cardiovascular effects of angiotensin-(1-7) in spontaneously hypertensive rats.

Höcht C, Opezzo JA, Gironacci MM, Peña C, Taira CA.

Regul Pept. 2006 Jul 15;135(1-2):39-44. Epub 2006 May 5.

PMID:
16678284
22.

Applicability of reverse microdialysis in pharmacological and toxicological studies.

Höcht C, Opezzo JA, Taira CA.

J Pharmacol Toxicol Methods. 2007 Jan-Feb;55(1):3-15. Epub 2006 Mar 6. Review.

PMID:
16567112
23.

Microdialysis in drug discovery.

Höcht C, Opezzo JA, Taira CA.

Curr Drug Discov Technol. 2004 Dec;1(4):269-85. Review.

PMID:
16472243
24.

Applicability of microdialysis as a technique for pharmacokinetic-pharmacodynamic (PK-PD) modeling of antihypertensive beta-blockers.

Höcht C, DiVerniero C, Opezzo JA, Taira CA.

J Pharmacol Toxicol Methods. 2005 Sep-Oct;52(2):244-50.

PMID:
16125622
25.

Hypothalamic antihypertensive effect of metoprolol in chronic aortic coarctated rats.

Höcht C, Opezzo JA, Taira CA.

Clin Exp Pharmacol Physiol. 2005 Aug;32(8):681-6.

PMID:
16120197
26.

Anterior hypothalamic beta-adrenoceptors in chronic aortic-coarctated hypertensive rats: an interaction with central angiotensin II receptors.

Höcht C, Opezzo JA, Gironacci MM, Peña C, Taira CA.

Clin Exp Pharmacol Physiol. 2005 Jan-Feb;32(1-2):30-4.

PMID:
15730431
27.

Hypothalamic antihypertensive effect of irbesartan in chronic aortic coarctated rats.

Höcht C, Opezzo JA, Taira CA.

Pharmacology. 2005 Mar;73(3):146-54. Epub 2004 Nov 26.

PMID:
15564789
28.

Pharmacokinetic-pharmacodynamic properties of metoprolol in chronic aortic coarctated rats.

Höcht C, Di Verniero C, Opezzo JA, Taira CA.

Naunyn Schmiedebergs Arch Pharmacol. 2004 Jul;370(1):1-8. Epub 2004 Jul 22.

PMID:
15300360
29.

Pharmacokinetics and the cardiovascular effects of irbesartan in aortic coarctated rats.

Höcht C, Opezzo JA, Taira CA.

Pharmacology. 2004 Jan;70(1):23-30.

PMID:
14646353
30.
31.

Study of the hypothalamic angiotensin system in aortic coarctated rats using the reverse microdialysis technique.

Höcht C, Opezzo JA, Gironacci M, Peña C, Taira CA.

Pharmacol Res. 2003 Sep;48(3):301-7.

PMID:
12860451
32.

Pharmacokinetic profile of methyldopa in the brain of sinaortic-denervated rats.

Opezzo JA, Höcht C, Taira CA.

Pharmacol Res. 2003 Jul;48(1):61-7.

PMID:
12770516
33.

Effects of clonidine on the experimental hypertension by abdominal aortic coarctation in rats.

Gorzalczany SB, Opezzo JA, del Carmen Garcia M, Taira CA.

Pharmacol Res. 2003 Jul;48(1):17-24.

PMID:
12770510
34.

In vivo and in vitro pharmacodynamic properties of metoprolol in aortic coarctated rats.

Höcht C, Di Verniero C, Opezzo JA, Taira CA.

Pharmacol Res. 2003 Mar;47(3):181-8.

PMID:
12591012
35.

Pharmacokinetic and pharmacodynamic alterations of methyldopa in rats with aortic coarctation. A study using microdialysis.

Höcht C, Opezzo JA, Gorzalczany SB, Priano RM, Bramuglia GF, Taira CA.

Pharmacol Res. 2001 Nov;44(5):377-83.

PMID:
11712868
36.

Pharmacokinetic study of methyldopa in aorta-coarctated rats using a microdialysis technique.

Opezzo JA, Höcht C, Taira CA, Bramuglia GF.

Pharmacol Res. 2001 Feb;43(2):155-9.

PMID:
11243717
37.

Study of the evolution of blood and striatal levels of methyldopa: a microdialysis study in sinaortic denervated rats.

Opezzo JA, Höcht C, Taira CA, Bramuglia GF.

Pharmacol Res. 2000 Apr;41(4):455-9.

PMID:
10704270
38.

Furosemide renal excretion rate and the effects of the diuretic on different tubular sites are modified by endogenous dopamine in normohydrated rats.

Nowicki S, Opezzo JA, Levin G, Gonzalez D, Elias MM.

J Pharmacol Exp Ther. 1995 Sep;274(3):1348-54.

PMID:
7562507

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