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Items: 1 to 50 of 168

1.

EGFR is required for Wnt9a-Fzd9b signalling specificity in haematopoietic stem cells.

Grainger S, Nguyen N, Richter J, Setayesh J, Lonquich B, Oon CH, Wozniak JM, Barahona R, Kamei CN, Houston J, Carrillo-Terrazas M, Drummond IA, Gonzalez D, Willert K, Traver D.

Nat Cell Biol. 2019 Jun;21(6):721-730. doi: 10.1038/s41556-019-0330-5. Epub 2019 May 20.

PMID:
31110287
2.

Asymmetric recruitment and actin-dependent cortical flows drive the neuroblast polarity cycle.

Oon CH, Prehoda KE.

Elife. 2019 May 8;8. pii: e45815. doi: 10.7554/eLife.45815.

3.

A Stromal Lysolipid-Autotaxin Signaling Axis Promotes Pancreatic Tumor Progression.

Auciello FR, Bulusu V, Oon C, Tait-Mulder J, Berry M, Bhattacharyya S, Tumanov S, Allen-Petersen BL, Link J, Kendsersky ND, Vringer E, Schug M, Novo D, Hwang RF, Evans RM, Nixon C, Dorrell C, Morton JP, Norman JC, Sears RC, Kamphorst JJ, Sherman MH.

Cancer Discov. 2019 May;9(5):617-627. doi: 10.1158/2159-8290.CD-18-1212. Epub 2019 Mar 5.

PMID:
30837243
4.

Lactobacillus Strains Alleviated Aging Symptoms and Aging-Induced Metabolic Disorders in Aged Rats.

Hor YY, Ooi CH, Khoo BY, Choi SB, Seeni A, Shamsuddin S, Oon CE, Ong KL, Jeong WS, Liong MT.

J Med Food. 2019 Jan;22(1):1-13. doi: 10.1089/jmf.2018.4229. Epub 2018 Dec 28.

PMID:
30592688
5.

Toxicological studies of Orthosiphon stamineus (Misai Kucing) standardized ethanol extract in combination with gemcitabine in athymic nude mice model.

Yehya AHS, Asif M, Kaur G, Hassan LEA, Al-Suede FSR, Abdul Majid AMS, Oon CE.

J Adv Res. 2018 May 9;15:59-68. doi: 10.1016/j.jare.2018.05.006. eCollection 2019 Jan.

6.

Establishment of in vitro and in vivo anti-colon cancer efficacy of essential oils containing oleo-gum resin extract of Mesua ferrea.

Asif M, Yehya AHS, Dahham SS, Mohamed SK, Shafaei A, Ezzat MO, Abdul Majid AS, Oon CE, Abdul Majid AMS.

Biomed Pharmacother. 2019 Jan;109:1620-1629. doi: 10.1016/j.biopha.2018.10.127. Epub 2018 Nov 15.

7.

Angiogenesis: Managing the Culprits behind Tumorigenesis and Metastasis.

Yehya AHS, Asif M, Petersen SH, Subramaniam AV, Kono K, Majid AMSA, Oon CE.

Medicina (Kaunas). 2018 Mar 25;54(1). pii: E8. doi: 10.3390/medicina54010008. Review.

8.

Functional Analysis of Circular RNAs.

Shanmugapriya, Huda HA, Vijayarathna S, Oon CE, Chen Y, Kanwar JR, Ng ML, Sasidharan S.

Adv Exp Med Biol. 2018;1087:95-105. doi: 10.1007/978-981-13-1426-1_8. Review.

PMID:
30259360
9.

Anticancer activities of a benzimidazole compound through sirtuin inhibition in colorectal cancer.

Tan YJ, Lee YT, Yeong KY, Petersen SH, Kono K, Tan SC, Oon CE.

Future Med Chem. 2018 Sep 1;10(17):2039-2057. doi: 10.4155/fmc-2018-0052. Epub 2018 Aug 1.

PMID:
30066578
10.

Molecular targeted therapy: Treating cancer with specificity.

Lee YT, Tan YJ, Oon CE.

Eur J Pharmacol. 2018 Sep 5;834:188-196. doi: 10.1016/j.ejphar.2018.07.034. Epub 2018 Jul 20. Review.

PMID:
30031797
11.

How glycosylation aids tumor angiogenesis: An updated review.

Cheng WK, Oon CE.

Biomed Pharmacother. 2018 Jul;103:1246-1252. doi: 10.1016/j.biopha.2018.04.119. Epub 2018 May 7. Review.

PMID:
29864905
12.

MicroRNA profiling in MDA-MB-231 human breast cancer cell exposed to the Phaleria macrocarpa (Boerl.) fruit ethyl acetate fraction (PMEAF) through IIlumina Hi-Seq technologies and various in silico bioinformatics tools.

Kavitha N, Vijayarathna S, Shanmugapriya, Oon CE, Chen Y, Kanwar JR, Punj V, Sasidharan S.

J Ethnopharmacol. 2018 Mar 1;213:118-131. doi: 10.1016/j.jep.2017.11.009. Epub 2017 Nov 14.

PMID:
29154802
13.

Mesua ferrea stem bark extract induces apoptosis and inhibits metastasis in human colorectal carcinoma HCT 116 cells, through modulation of multiple cell signalling pathways.

Asif M, Shafaei A, Abdul Majid AS, Ezzat MO, Dahham SS, Ahamed MBK, Oon CE, Abdul Majid AMS.

Chin J Nat Med. 2017 Jul;15(7):505-514. doi: 10.1016/S1875-5364(17)30076-6.

PMID:
28807224
14.

Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth.

Oon CE, Bridges E, Sheldon H, Sainson RCA, Jubb A, Turley H, Leek R, Buffa F, Harris AL, Li JL.

Oncotarget. 2017 Jun 20;8(25):40115-40131. doi: 10.18632/oncotarget.16969.

15.

Polyalthia longifolia Methanolic Leaf Extracts (PLME) induce apoptosis, cell cycle arrest and mitochondrial potential depolarization by possibly modulating the redox status in hela cells.

Vijayarathna S, Oon CE, Chen Y, Kanwar JR, Sasidharan S.

Biomed Pharmacother. 2017 May;89:499-514. doi: 10.1016/j.biopha.2017.02.075. Epub 2017 Feb 27.

PMID:
28249252
16.

CRISPR Guide RNA Validation In Vitro.

Grainger S, Lonquich B, Oon CH, Nguyen N, Willert K, Traver D.

Zebrafish. 2017 Aug;14(4):383-386. doi: 10.1089/zeb.2016.1358. Epub 2016 Nov 9.

17.

Isoledene from Mesua ferrea oleo-gum resin induces apoptosis in HCT 116 cells through ROS-mediated modulation of multiple proteins in the apoptotic pathways: A mechanistic study.

Asif M, Shafaei A, Jafari SF, Mohamed SK, Ezzat MO, Abdul Majid AS, Oon CE, Petersen SH, Kono K, Abdul Majid AM.

Toxicol Lett. 2016 Aug 22;257:84-96. doi: 10.1016/j.toxlet.2016.05.027. Epub 2016 Jun 3.

PMID:
27268964
18.

Scopoletin, an active principle of tree tobacco (Nicotiana glauca) inhibits human tumor vascularization in xenograft models and modulates ERK1, VEGF-A, and FGF-2 in computer model.

Tabana YM, Hassan LE, Ahamed MB, Dahham SS, Iqbal MA, Saeed MA, Khan MS, Sandai D, Majid AS, Oon CE, Majid AM.

Microvasc Res. 2016 Sep;107:17-33. doi: 10.1016/j.mvr.2016.04.009. Epub 2016 Apr 29.

PMID:
27133199
19.

Sirtuin Inhibitors: An Overview from Medicinal Chemistry Perspective.

Yoon YK, Oon CE.

Anticancer Agents Med Chem. 2016;16(8):1003-1016. doi: 10.2174/1871520616666160310141622.

PMID:
26961318
20.

Human colon cancer targeted pro-apoptotic, anti-metastatic and cytostatic effects of binuclear Silver(I)-N-Heterocyclic carbene (NHC) complexes.

Asif M, Iqbal MA, Hussein MA, Oon CE, Haque RA, Khadeer Ahamed MB, Abdul Majid AS, Abdul Majid AMS.

Eur J Med Chem. 2016 Jan 27;108:177-187. doi: 10.1016/j.ejmech.2015.11.034. Epub 2015 Nov 25.

PMID:
26649905
21.

SIRT1 inhibition in pancreatic cancer models: contrasting effects in vitro and in vivo.

Oon CE, Strell C, Yeong KY, Östman A, Prakash J.

Eur J Pharmacol. 2015 Jun 15;757:59-67. doi: 10.1016/j.ejphar.2015.03.064. Epub 2015 Apr 3.

PMID:
25843411
22.

MicroRNAs: biogenesis, roles for carcinogenesis and as potential biomarkers for cancer diagnosis and prognosis.

Kavitha N, Vijayarathna S, Jothy SL, Oon CE, Chen Y, Kanwar JR, Sasidharan S.

Asian Pac J Cancer Prev. 2014;15(18):7489-97. Review.

23.

Natural pro-oxidants: an alternative remedy to explore as novel cancer therapeutic agents.

Jothy SL, Oon CE, Sasidharan S.

Asian Pac J Cancer Prev. 2014;15(3):1501. No abstract available.

24.

MicroRNA pathways: an emerging role in identification of therapeutic strategies.

Vijayarathna S, Oon CE, Jothy SL, Chen Y, Kanwar JR, Sasidharan S.

Curr Gene Ther. 2014;14(2):112-20. Review.

PMID:
24588707
25.

Herbal remedies for combating irradiation: a green anti-irradiation approach.

Lachumy SJ, Oon CE, Deivanai S, Saravanan D, Vijayarathna S, Choong YS, Yeng C, Latha LY, Sasidharan S.

Asian Pac J Cancer Prev. 2013;14(10):5553-65. Review.

26.

Rapamycin induces apoptosis when autophagy is inhibited in T-47D mammary cells and both processes are regulated by Phlda1.

Moad AI, Muhammad TS, Oon CE, Tan ML.

Cell Biochem Biophys. 2013 Jul;66(3):567-87. doi: 10.1007/s12013-012-9504-5.

PMID:
23300026
27.

Haploidentical related-donor hematopoietic cell transplantation in children using megadoses of CliniMACs-selected CD34(+) cells and a fixed CD3(+) dose.

Dvorak CC, Gilman AL, Horn B, Oon CY, Dunn EA, Baxter-Lowe LA, Cowan MJ.

Bone Marrow Transplant. 2013 Apr;48(4):508-13. doi: 10.1038/bmt.2012.186. Epub 2012 Nov 26.

PMID:
23178543
28.

New pathways and mechanisms regulating and responding to Delta-like ligand 4-Notch signalling in tumour angiogenesis.

Oon CE, Harris AL.

Biochem Soc Trans. 2011 Dec;39(6):1612-8. doi: 10.1042/BST20110721. Review.

PMID:
22103496
29.

Identification of genes involved in the regulation of 14-deoxy-11,12-didehydroandrographolide-induced toxicity in T-47D mammary cells.

Tan ML, Tan HK, Oon CE, Kuroyanagi M, Muhammad TS.

Food Chem Toxicol. 2012 Feb;50(2):431-44. doi: 10.1016/j.fct.2011.11.001. Epub 2011 Nov 11.

PMID:
22101062
30.

DLL4-Notch signaling mediates tumor resistance to anti-VEGF therapy in vivo.

Li JL, Sainson RC, Oon CE, Turley H, Leek R, Sheldon H, Bridges E, Shi W, Snell C, Bowden ET, Wu H, Chowdhury PS, Russell AJ, Montgomery CP, Poulsom R, Harris AL.

Cancer Res. 2011 Sep 15;71(18):6073-83. doi: 10.1158/0008-5472.CAN-11-1704. Epub 2011 Jul 29.

31.

Cytotoxic effects of commercial wheatgrass and fiber towards human acute promyelocytic leukemia cells (HL60).

Alitheen NB, Oon CL, Keong YS, Chuan TK, Li HK, Yong HW.

Pak J Pharm Sci. 2011 Jul;24(3):243-50.

PMID:
21715255
32.

Notch regulation of tumor angiogenesis.

Bridges E, Oon CE, Harris A.

Future Oncol. 2011 Apr;7(4):569-88. doi: 10.2217/fon.11.20. Review.

PMID:
21463145
33.

New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes.

Sheldon H, Heikamp E, Turley H, Dragovic R, Thomas P, Oon CE, Leek R, Edelmann M, Kessler B, Sainson RC, Sargent I, Li JL, Harris AL.

Blood. 2010 Sep 30;116(13):2385-94. doi: 10.1182/blood-2009-08-239228. Epub 2010 Jun 17.

34.

Simple, low-cost technique for photolithographic self-aligned top metal contacts to nanowires and nanotubes.

Oon CH, Thong JT.

Nanotechnology. 2008 Nov 12;19(45):455305. doi: 10.1088/0957-4484/19/45/455305. Epub 2008 Oct 8.

PMID:
21832770
35.
37.

Prevention of human hepatocellular carcinoma with natural lymphoblastoid alpha interferon.

Oon CJ.

J Gastroenterol Hepatol. 2002 Dec;17 Suppl:S500-1. Review.

PMID:
12534786
38.

Hepatitis B virus mutants: an overview.

Chen WN, Oon CJ.

J Gastroenterol Hepatol. 2002 Dec;17 Suppl:S497-9. Review. No abstract available.

PMID:
12534785
39.

Molecular characterization of hepatitis B virus surface antigen mutants in Singapore patients with hepatocellular carcinoma and hepatitis B virus carriers negative for HBsAg but positive for anti-HBs and anti-HBc.

Oon CJ, Chen WN, Goh KT, Mesenas S, Ng HS, Chiang G, Tan C, Koh S, Teng SW, Toh I, Moh MC, Goo KS, Tan K, Leong AL, Tan GS.

J Gastroenterol Hepatol. 2002 Dec;17 Suppl:S491-6.

PMID:
12534784
40.

Preliminary experience in radionuclide therapy of hepatocellular carcinoma using hepatic intra-arterial radio-conjugates.

Keng GH, Sundram FX, Yu SW, Somanesan S, Premaraj J, Oon CJ, Kwok R, Htoo MM.

Ann Acad Med Singapore. 2002 May;31(3):382-6.

PMID:
12061301
41.

Hepatitis B virus surface antigen mutants persist in chronic carriers receiving lamivudine therapy in Singapore.

Chen WN, Oon CJ, Lim GK.

J Antimicrob Chemother. 2002 Jun;49(6):1044-6. No abstract available.

PMID:
12039904
42.

Wild-type and 'a' epitope variants in chronic hepatitis B virus carriers positive for hepatitis B surface antigen and antibody.

Mesenas SJ, Chow WC, Zhao Y, Lim GK, Oon CJ, Ng HS.

J Gastroenterol Hepatol. 2002 Feb;17(2):148-52.

PMID:
11966944
43.
44.

Frequent occurrence of hepatitis B virus surface antigen mutants in subtype adw in vaccinated Singapore infants.

Chen WN, Oon CJ, Lim GK.

Vaccine. 2001 Dec 12;20(5-6):639-40. No abstract available.

PMID:
11738727
45.
46.

Intra-familial evidence of horizontal transmission of hepatitis B virus surface antigen mutant G145R.

Oon CJ, Chen WN, Goo KS, Goh KT.

J Infect. 2000 Nov;41(3):260-4.

PMID:
11120616
47.

Boerhaave's syndrome (ruptured oesophagus) in a case of rabies.

Oon CT.

Singapore Med J. 2000 Feb;41(2):83-5.

PMID:
11063210
48.

Expression of integrated hepatitis B virus X variants in human hepatocellular carcinomas and its significance.

Chen WN, Oon CJ, Leong AL, Koh S, Teng SW.

Biochem Biophys Res Commun. 2000 Oct 5;276(3):885-92.

PMID:
11027564

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