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Items: 1 to 50 of 345

1.

Circulating microRNAs as Potential Diagnostic and Prognostic Biomarkers in Hepatocellular Carcinoma.

Jin Y, Wong YS, Goh BKP, Chan CY, Cheow PC, Chow PKH, Lim TKH, Goh GBB, Krishnamoorthy TL, Kumar R, Ng TP, Chong SS, Tan HH, Chung AYF, Ooi LLPJ, Chang JPE, Tan CK, Lee CGL.

Sci Rep. 2019 Jul 18;9(1):10464. doi: 10.1038/s41598-019-46872-8.

PMID:
31320713
2.

Loss of Cln5 leads to altered Gad1 expression and deficits in interneuron development in mice.

Singh Y, Leinonen H, Fazaludeen F, Jaronen M, Guest D, Buckley N, Byts N, Oksa P, Jalkanen K, Iqbal I, Huuskonen M, Savchenko E, Keksa-Goldsteine V, Chew S, Myllyharju J, Tanila H, Ooi L, Koistinaho J, Kanninen KM, Malm T.

Hum Mol Genet. 2019 Jul 11. pii: ddz165. doi: 10.1093/hmg/ddz165. [Epub ahead of print]

PMID:
31294445
3.

Preoperative Predictors Including the Role of Inflammatory Indices in Predicting Early Recurrence After Re-resection for Recurrent Hepatocellular Carcinoma.

Guo Y, Chua DW, Koh YX, Lee SY, Cheow PC, Kam JH, Teo JY, Chow PK, Chung AY, Ooi LL, Chan CY, Goh BKP.

World J Surg. 2019 Jun 20. doi: 10.1007/s00268-019-05051-6. [Epub ahead of print]

PMID:
31222641
4.

The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation.

Bax M, McKenna J, Do-Ha D, Stevens CH, Higginbottom S, Balez R, Cabral-da-Silva MEC, Farrawell NE, Engel M, Poronnik P, Yerbury JJ, Saunders DN, Ooi L.

Cells. 2019 Jun 13;8(6). pii: E581. doi: 10.3390/cells8060581.

5.

Increased Tau Phosphorylation in Motor Neurons From Clinically Pure Sporadic Amyotrophic Lateral Sclerosis Patients.

Stevens CH, Guthrie NJ, van Roijen M, Halliday GM, Ooi L.

J Neuropathol Exp Neurol. 2019 Jul 1;78(7):605-614. doi: 10.1093/jnen/nlz041.

PMID:
31131395
6.

Antibiotic Use and Outcomes After Implementation of the Drug Resistance in Pneumonia Score in ED Patients With Community-Onset Pneumonia.

Webb BJ, Sorensen J, Mecham I, Buckel W, Ooi L, Jephson A, Dean NC.

Chest. 2019 May 8. pii: S0012-3692(19)31012-8. doi: 10.1016/j.chest.2019.04.093. [Epub ahead of print]

PMID:
31077649
7.

Low plasma vitamin D is associated with adverse colorectal cancer survival after surgical resection, independent of systemic inflammatory response.

Vaughan-Shaw PG, Zgaga L, Ooi LY, Theodoratou E, Timofeeva M, Svinti V, Walker M, O'Sullivan F, Ewing A, Johnston S, Din FVN, Campbell H, Farrington SM, Dunlop MG.

Gut. 2019 Apr 25. pii: gutjnl-2018-317922. doi: 10.1136/gutjnl-2018-317922. [Epub ahead of print]

8.

Genome-wide CRISPR knockout screens identify NCAPG as an essential oncogene for hepatocellular carcinoma tumor growth.

Wang Y, Gao B, Tan PY, Handoko YA, Sekar K, Deivasigamani A, Seshachalam VP, OuYang HY, Shi M, Xie C, Goh BKP, Ooi LL, Man Hui K.

FASEB J. 2019 Apr 25:fj201802213RR. doi: 10.1096/fj.201802213RR. [Epub ahead of print]

9.

Impact of spontaneous rupture on the survival outcomes after liver resection for hepatocellular carcinoma: A propensity matched analysis comparing ruptured versus non-ruptured tumors.

Chua DW, Koh YX, Allen JC, Chan CY, Lee SY, Cheow PC, Jeyaraj P, Teo JY, Chow PK, Chung AY, Ooi LL, Goh BKP.

Eur J Surg Oncol. 2019 Apr 9. pii: S0748-7983(19)30389-0. doi: 10.1016/j.ejso.2019.03.044. [Epub ahead of print]

PMID:
31003720
10.

The metastability of the proteome of spinal motor neurons underlies their selective vulnerability in ALS.

Yerbury JJ, Ooi L, Blair IP, Ciryam P, Dobson CM, Vendruscolo M.

Neurosci Lett. 2019 Jun 21;704:89-94. doi: 10.1016/j.neulet.2019.04.001. Epub 2019 Apr 3.

PMID:
30953736
11.

Dynamic interplay between H-current and M-current controls motoneuron hyperexcitability in amyotrophic lateral sclerosis.

Buskila Y, Kékesi O, Bellot-Saez A, Seah W, Berg T, Trpceski M, Yerbury JJ, Ooi L.

Cell Death Dis. 2019 Apr 5;10(4):310. doi: 10.1038/s41419-019-1538-9.

12.

External validation of the Japanese difficulty scoring system for minimally-invasive distal pancreatectomies.

Goh BKP, Kabir T, Koh YX, Teo JY, Lee SY, Kam JH, Cheow PC, Jeyaraj PR, Chow PKH, Ooi LLPJ, Chung AYF, Chan CY.

Am J Surg. 2019 Mar 15. pii: S0002-9610(19)30194-1. doi: 10.1016/j.amjsurg.2019.03.012. [Epub ahead of print]

PMID:
30910129
13.

Initial single institution experience with robotic biliary surgery and bilio-enteric anastomosis in southeast Asia.

Goh BKP, Low TY, Teo JY, Lee SY, Chan CY, Chung AYF, Ooi LLPJ.

ANZ J Surg. 2019 Apr;89(4):E142-E146. doi: 10.1111/ans.15135. Epub 2019 Mar 18.

PMID:
30887681
14.

Periventricular White Matter Abnormalities on Diffusion Tensor Imaging of Postural Instability Gait Disorder Parkinsonism.

Tan SYZ, Keong NCH, Selvan RMP, Li H, Ooi LQR, Tan EK, Chan LL.

AJNR Am J Neuroradiol. 2019 Apr;40(4):609-613. doi: 10.3174/ajnr.A5993. Epub 2019 Mar 14.

PMID:
30872421
15.

NUF2 is a valuable prognostic biomarker to predict early recurrence of hepatocellular carcinoma after surgical resection.

Wang Y, Tan PY, Handoko YA, Sekar K, Shi M, Xie C, Jiang XD, Dong QZ, Goh BKP, Ooi LL, Gao Z, Hui KM.

Int J Cancer. 2019 Aug 1;145(3):662-670. doi: 10.1002/ijc.32134. Epub 2019 Feb 4.

PMID:
30653265
16.

Novel dual-action prodrug triggers apoptosis in glioblastoma cells by releasing a glutathione quencher and lysine-specific histone demethylase 1A inhibitor.

Engel M, Gee YS, Cross D, Maccarone A, Heng B, Hulme A, Smith G, Guillemin GJ, Stringer BW, Hyland CJT, Ooi L.

J Neurochem. 2019 May;149(4):535-550. doi: 10.1111/jnc.14655. Epub 2019 Feb 3.

17.

Laparoscopic Liver Resection Difficulty Score-a Validation Study.

Lee SY, Goh BKP, Sepideh G, Allen JC, Merkow RP, Teo JY, Chandra D, Koh YX, Tan EK, Kam JH, Cheow PC, Chow PKH, Ooi LLPJ, Chung AYF, D'Angelica MI, Jarnagin WR, Peter Kingham T, Chan CY.

J Gastrointest Surg. 2019 Mar;23(3):545-555. doi: 10.1007/s11605-018-4036-y. Epub 2018 Nov 12.

PMID:
30421119
18.

Pre-operative predictors of early recurrence/mortality including the role of inflammatory indices in patients undergoing partial hepatectomy for spontaneously ruptured hepatocellular carcinoma.

Chua DW, Koh YX, Liew YX, Chan CY, Lee SY, Cheow PC, Chow PK, Chung AY, Ooi LL, Goh BK.

J Surg Oncol. 2018 Dec;118(8):1227-1236. doi: 10.1002/jso.25281. Epub 2018 Nov 6.

PMID:
30399204
19.

Perioperative Outcomes of Laparoscopic Repeat Liver Resection for Recurrent HCC: Comparison with Open Repeat Liver Resection for Recurrent HCC and Laparoscopic Resection for Primary HCC.

Goh BKP, Syn N, Teo JY, Guo YX, Lee SY, Cheow PC, Chow PKH, Ooi LLPJ, Chung AYF, Chan CY.

World J Surg. 2019 Mar;43(3):878-885. doi: 10.1007/s00268-018-4828-y.

PMID:
30361747
20.

Viral-free generation and characterization of a human induced pluripotent stem cell line from dermal fibroblasts.

Engel M, Balez R, Muñoz SS, Cabral-da-Silva MC, Stevens CH, Bax M, Do-Ha D, Sidhu K, Sachdev P, Ooi L.

Stem Cell Res. 2018 Oct;32:135-138. doi: 10.1016/j.scr.2018.09.014. Epub 2018 Sep 19.

21.

Sad, Scared, or Rejected? A Short-Term Longitudinal Study of the Predictors of Social Avoidance in Chinese Children.

Ding X, Coplan RJ, Deng X, Ooi LL, Li D, Sang B.

J Abnorm Child Psychol. 2019 Jul;47(7):1265-1276. doi: 10.1007/s10802-018-0476-9.

PMID:
30246230
22.

Understanding the Role of ApoE Fragments in Alzheimer's Disease.

Muñoz SS, Garner B, Ooi L.

Neurochem Res. 2019 Jun;44(6):1297-1305. doi: 10.1007/s11064-018-2629-1. Epub 2018 Sep 17. Review.

PMID:
30225748
23.

CDK1-mediated BCL9 phosphorylation inhibits clathrin to promote mitotic Wnt signalling.

Chen J, Rajasekaran M, Xia H, Kong SN, Deivasigamani A, Sekar K, Gao H, Swa HL, Gunaratne J, Ooi LL, Xie T, Hong W, Hui KM.

EMBO J. 2018 Oct 15;37(20). pii: e99395. doi: 10.15252/embj.201899395. Epub 2018 Sep 14.

PMID:
30217955
24.

A retrospective review of correlative radiological assessment and surgical exploration for hilar cholangiocarcinoma.

Chua D, Low A, Koh Y, Goh B, Cheow PC, Kam JH, Teo JY, Tan EK, Chung A, Ooi LL, Chan CY, Lee SY.

Ann Hepatobiliary Pancreat Surg. 2018 Aug;22(3):216-222. doi: 10.14701/ahbps.2018.22.3.216. Epub 2018 Aug 31.

25.

Predictors of post-hepatectomy liver failure in patients undergoing extensive liver resections for hepatocellular carcinoma.

Chin KM, Allen JC, Teo JY, Kam JH, Tan EK, Koh Y, Goh KPB, Cheow PC, Raj P, Chow KHP, Chung YFA, Ooi LL, Chan CY, Lee SY.

Ann Hepatobiliary Pancreat Surg. 2018 Aug;22(3):185-196. doi: 10.14701/ahbps.2018.22.3.185. Epub 2018 Aug 31.

26.

Generation and characterization of human induced pluripotent stem cell lines from a familial Alzheimer's disease PSEN1 A246E patient and a non-demented family member bearing wild-type PSEN1.

Muñoz SS, Balez R, Castro Cabral-da-Silva ME, Berg T, Engel M, Bax M, Do-Ha D, Stevens CH, Greenough M, Bush A, Ooi L.

Stem Cell Res. 2018 Aug;31:227-230. doi: 10.1016/j.scr.2018.08.006. Epub 2018 Aug 13.

27.

Curvature contribution on anodic aluminium oxide pore formation: a detailed analytical study.

Tiong TY, Ooi L, Dee CF, Hamzah AA, Majlis BY.

Nanotechnology. 2018 Oct 26;29(43):435601. doi: 10.1088/1361-6528/aad884. Epub 2018 Aug 7.

PMID:
30084385
28.

Astrocytic modulation of cortical oscillations.

Bellot-Saez A, Cohen G, van Schaik A, Ooi L, W Morley J, Buskila Y.

Sci Rep. 2018 Aug 1;8(1):11565. doi: 10.1038/s41598-018-30003-w.

29.

Perioperative Outcomes of Laparoscopic Minor Hepatectomy for Hepatocellular Carcinoma in the Elderly.

Goh BKP, Chua D, Syn N, Teo JY, Chan CY, Lee SY, Jeyaraj PR, Cheow PC, Chow PKH, Ooi LLPJ, Chung AYF.

World J Surg. 2018 Dec;42(12):4063-4069. doi: 10.1007/s00268-018-4741-4.

PMID:
30062545
30.

The mechanism of SO2 -induced stomatal closure differs from O3 and CO2 responses and is mediated by nonapoptotic cell death in guard cells.

Ooi L, Matsuura T, Munemasa S, Murata Y, Katsuhara M, Hirayama T, Mori IC.

Plant Cell Environ. 2019 Feb;42(2):437-447. doi: 10.1111/pce.13406. Epub 2018 Oct 3.

PMID:
30014483
31.

Changing trends and outcomes associated with the adoption of minimally invasive hepatectomy: a contemporary single-institution experience with 400 consecutive resections.

Goh BKP, Lee SY, Teo JY, Kam JH, Jeyaraj PR, Cheow PC, Chow PKH, Ooi LLPJ, Chung AYF, Chan CY.

Surg Endosc. 2018 Nov;32(11):4658-4665. doi: 10.1007/s00464-018-6310-1. Epub 2018 Jul 2.

PMID:
29967997
32.

Identification and High-Resolution Imaging of α-Tocopherol from Human Cells to Whole Animals by TOF-SIMS Tandem Mass Spectrometry.

Bruinen AL, Fisher GL, Balez R, van der Sar AM, Ooi L, Heeren RMA.

J Am Soc Mass Spectrom. 2018 Aug;29(8):1571-1581. doi: 10.1007/s13361-018-1979-x. Epub 2018 Jun 12.

33.

Chronic Adolescent CDPPB Treatment Alters Short-Term, but not Long-Term, Glutamatergic Receptor Expression.

Lum JS, Millard SJ, Frank E, Matosin N, Huang XF, Ooi L, Newell KA.

Neurochem Res. 2018 Aug;43(8):1683-1691. doi: 10.1007/s11064-018-2584-x. Epub 2018 Jun 23.

PMID:
29936568
34.

Initial experience with robotic pancreatic surgery in Singapore: single institution experience with 30 consecutive cases.

Goh BKP, Low TY, Lee SY, Chan CY, Chung AYF, Ooi LLPJ.

ANZ J Surg. 2019 Mar;89(3):206-210. doi: 10.1111/ans.14673. Epub 2018 May 24.

PMID:
29799169
35.

A postmortem analysis of NMDA ionotropic and group 1 metabotropic glutamate receptors in the nucleus accumbens in schizophrenia.

Lum JS, Millard SJ, Huang XF, Ooi L, Newell KA.

J Psychiatry Neurosci. 2018 Mar;43(2):102-110.

36.
37.

The serine protease HtrA1 contributes to the formation of an extracellular 25-kDa apolipoprotein E fragment that stimulates neuritogenesis.

Muñoz SS, Li H, Ruberu K, Chu Q, Saghatelian A, Ooi L, Garner B.

J Biol Chem. 2018 Mar 16;293(11):4071-4084. doi: 10.1074/jbc.RA117.001278. Epub 2018 Feb 2.

39.

Young children's preference for solitary play: Implications for socio-emotional and school adjustment.

Ooi LL, Baldwin D, Coplan RJ, Rose-Krasnor L.

Br J Dev Psychol. 2018 Sep;36(3):501-507. doi: 10.1111/bjdp.12236. Epub 2018 Jan 22.

PMID:
29356027
40.

Effects of short- and long-term aripiprazole treatment on Group I mGluRs in the nucleus accumbens: Comparison with haloperidol.

Lum JS, Pan B, Deng C, Huang XF, Ooi L, Newell KA.

Psychiatry Res. 2018 Feb;260:152-157. doi: 10.1016/j.psychres.2017.11.048. Epub 2017 Nov 21.

PMID:
29195167
41.

A Retrospective Review of the Diagnostic and Management Challenges of Mirizzi Syndrome at the Singapore General Hospital.

Seah WM, Koh YX, Cheow PC, Chow PKH, Chan CY, Lee SY, Ooi LLPJ, Chung AYF, Goh BKP.

Dig Surg. 2018;35(6):491-497. doi: 10.1159/000484256. Epub 2017 Nov 30.

PMID:
29190631
42.

A postmortem analysis of NMDA ionotropic and group 1 metabotropic glutamate receptors in the nucleus accumbens in schizophrenia.

Lum JS, Millard SJ, Huang XF, Ooi L, Newell KA.

J Psychiatry Neurosci. 2017 Nov;42(6):170077. doi: 10.1503/jpn.170077. Epub 2017 Oct 6.

43.

Early experience with robot-assisted laparoscopic hepatobiliary and pancreatic surgery in Singapore: single-institution experience with 20 consecutive patients.

Goh BK, Lee SY, Chan CY, Wong JS, Cheow PC, Chung AY, Ooi LL.

Singapore Med J. 2018 Mar;59(3):133-138. doi: 10.11622/smedj.2017092. Epub 2017 Oct 6.

44.

Evolution of minimally invasive distal pancreatectomies at a single institution.

Goh BKP, Lee SY, Kam JH, Soh HL, Cheow PC, Chow PKH, Ooi LLPJ, Chung AYF, Chan CY.

J Minim Access Surg. 2018 Apr-Jun;14(2):140-145. doi: 10.4103/jmas.JMAS_26_17.

45.

The heat shock response in neurons and astroglia and its role in neurodegenerative diseases.

San Gil R, Ooi L, Yerbury JJ, Ecroyd H.

Mol Neurodegener. 2017 Sep 18;12(1):65. doi: 10.1186/s13024-017-0208-6. Review.

46.

Critical appraisal of the impact of individual surgeon experience on the outcomes of laparoscopic liver resection in the modern era: collective experience of multiple surgeons at a single institution with 324 consecutive cases.

Goh BKP, Teo JY, Lee SY, Kam JH, Cheow PC, Jeyaraj P, Chow PKH, Ooi LLPJ, Chung AYF, Chan CY.

Surg Endosc. 2018 Apr;32(4):1802-1811. doi: 10.1007/s00464-017-5864-7. Epub 2017 Sep 15.

PMID:
28916894
47.

Simultaneous silencing of ACSL4 and induction of GADD45B in hepatocellular carcinoma cells amplifies the synergistic therapeutic effect of aspirin and sorafenib.

Xia H, Lee KW, Chen J, Kong SN, Sekar K, Deivasigamani A, Seshachalam VP, Goh BKP, Ooi LL, Hui KM.

Cell Death Discov. 2017 Sep 11;3:17058. doi: 10.1038/cddiscovery.2017.58. eCollection 2017.

48.

Preoperative Prognostic Factors After Liver Resection for Non-Colorectal, Non-Neuroendocrine Liver Metastases and Validation of the Adam Score in an Asian Population.

Sim DPY, Goh BKP, Lee SY, Chan CY, Tan IBH, Cheow PC, Jeyaraj P, Chow PKH, Ooi LLPJ, Chung AYF.

World J Surg. 2018 Apr;42(4):1073-1084. doi: 10.1007/s00268-017-4208-z.

PMID:
28875334
49.

GATA4 loss of function in liver cancer impedes precursor to hepatocyte transition.

Enane FO, Shuen WH, Gu X, Quteba E, Przychodzen B, Makishima H, Bodo J, Ng J, Chee CL, Ba R, Seng Koh L, Lim J, Cheong R, Teo M, Hu Z, Ng KP, Maciejewski J, Radivoyevitch T, Chung A, Ooi LL, Tan YM, Cheow PC, Chow P, Chan CY, Lim KH, Yerian L, Hsi E, Toh HC, Saunthararajah Y.

J Clin Invest. 2017 Sep 1;127(9):3527-3542. doi: 10.1172/JCI93488. Epub 2017 Jul 31.

50.

Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma.

Jusakul A, Cutcutache I, Yong CH, Lim JQ, Huang MN, Padmanabhan N, Nellore V, Kongpetch S, Ng AWT, Ng LM, Choo SP, Myint SS, Thanan R, Nagarajan S, Lim WK, Ng CCY, Boot A, Liu M, Ong CK, Rajasegaran V, Lie S, Lim AST, Lim TH, Tan J, Loh JL, McPherson JR, Khuntikeo N, Bhudhisawasdi V, Yongvanit P, Wongkham S, Totoki Y, Nakamura H, Arai Y, Yamasaki S, Chow PK, Chung AYF, Ooi LLPJ, Lim KH, Dima S, Duda DG, Popescu I, Broet P, Hsieh SY, Yu MC, Scarpa A, Lai J, Luo DX, Carvalho AL, Vettore AL, Rhee H, Park YN, Alexandrov LB, Gordân R, Rozen SG, Shibata T, Pairojkul C, Teh BT, Tan P.

Cancer Discov. 2017 Oct;7(10):1116-1135. doi: 10.1158/2159-8290.CD-17-0368. Epub 2017 Jun 30.

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