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Application of the cellular oxidation biosensor to Toxicity Identification Evaluations for high-throughput toxicity assessment of river water.

Ooi L, Okazaki K, Arias-Barreiro CR, Heng LY, Mori IC.

Chemosphere. 2020 May;247:125933. doi: 10.1016/j.chemosphere.2020.125933. Epub 2020 Jan 16.


More than a Corepressor: The Role of CoREST Proteins in Neurodevelopment.

Maksour S, Ooi L, Dottori M.

eNeuro. 2020 Mar 10;7(2). pii: ENEURO.0337-19.2020. doi: 10.1523/ENEURO.0337-19.2020. Print 2020 Mar/Apr. Review.


Pharmacological and genetic characterisation of the canine P2X4 receptor.

Sophocleous RA, Berg T, Finol-Urdaneta RK, Sluyter V, Keshiya S, Bell L, Curtis SJ, Curtis BL, Seavers A, Bartlett R, Dowton M, Stokes L, Ooi L, Sluyter R.

Br J Pharmacol. 2020 Feb 4. doi: 10.1111/bph.15009. [Epub ahead of print]


Effect of remote ischemic preConditioning on liver injury in patients undergoing liver resection: the ERIC-LIVER trial.

Teo JY, Ho AFW, Bulluck H, Gao F, Chong J, Koh YX, Tan EK, Abdul Latiff JB, Chua SH, Goh BKP, Chan CY, Chung AYF, Lee SY, Cheow PC, Ooi LLPJ, Davidson BR, Jevaraj PR, Hausenloy DJ.

HPB (Oxford). 2020 Jan 30. pii: S1365-182X(19)33218-6. doi: 10.1016/j.hpb.2019.12.002. [Epub ahead of print]


The mRNA-based reprogramming of fibroblasts from a SOD1E101G familial amyotrophic lateral sclerosis patient to induced pluripotent stem cell line UOWi007.

Balez R, Berg T, Bax M, Muñoz SS, Cabral-da-Silva MC, Engel M, Do-Ha D, Stevens CH, Rowe D, Yang S, Blair IP, Ooi L.

Stem Cell Res. 2020 Jan;42:101701. doi: 10.1016/j.scr.2020.101701. Epub 2020 Jan 16.


Increased Activation of Default Mode Network in Early Parkinson's With Excessive Daytime Sleepiness.

Ooi LQR, Wen MC, Ng SY, Chia NS, Chew IHM, Lee W, Xu Z, Hartono S, Tan EK, Chan LL, Tan LC.

Front Neurosci. 2019 Dec 12;13:1334. doi: 10.3389/fnins.2019.01334. eCollection 2019.


Variation for heterodimerization and nuclear localization among known and novel oil palm SHELL alleles.

Singh R, Low EL, Ooi LC, Ong-Abdullah M, Ting NC, Nookiah R, Ithnin M, Marjuni M, Mustaffa S, Yaakub Z, Amiruddin MD, Manaf MAA, Chan KL, Halim MAA, Sanusi NSNM, Lakey N, Sachdeva M, Bacher B, Garner PA, MacDonald JD, Smith SW, Wischmeyer C, Budiman MA, Beil M, Stroff C, Reed J, Van Brunt A, Berg H, Ordway JM, Sambanthamurthi R.

New Phytol. 2020 Apr;226(2):426-440. doi: 10.1111/nph.16387. Epub 2020 Jan 28.


Effect of surgical delay on survival outcomes in patients undergoing curative resection for primary hepatocellular carcinoma: Inverse probability of treatment weighting using propensity scores and propensity score adjustment.

Kabir T, Syn N, Ramkumar M, Yeo EYJ, Teo JY, Koh YX, Lee SY, Cheow PC, Chow PKH, Chung AYF, Ooi LL, Chan CY, Goh BKP.

Surgery. 2020 Feb;167(2):417-424. doi: 10.1016/j.surg.2019.09.022. Epub 2019 Oct 31.


Changing trends and outcomes associated with the adoption of minimally invasive pancreatic surgeries: A single institution experience with 150 consecutive procedures in Southeast Asia.

Goh BK, Low TY, Koh YX, Lee SY, Teo JY, Kam JH, Jeyaraj PR, Cheow PC, Chow PK, Ooi LL, Chung AY, Chan CY.

J Minim Access Surg. 2019 Oct 1. doi: 10.4103/jmas.JMAS_127_19. [Epub ahead of print]


Critical Appraisal of the Impact of the Systematic Adoption of Advanced Minimally Invasive Hepatobiliary and Pancreatic Surgery on the Surgical Management of Mirizzi Syndrome.

Koh YX, Basu P, Liew YX, Teo JY, Kam JH, Lee SY, Cheow PC, Jeyaraj P, Chow PKH, Chung AYF, Ooi LLPJ, Chan CY, Goh BKP.

World J Surg. 2019 Dec;43(12):3138-3152. doi: 10.1007/s00268-019-05164-y.


PSEN1ΔE9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia.

Konttinen H, Cabral-da-Silva MEC, Ohtonen S, Wojciechowski S, Shakirzyanova A, Caligola S, Giugno R, Ishchenko Y, Hernández D, Fazaludeen MF, Eamen S, Budia MG, Fagerlund I, Scoyni F, Korhonen P, Huber N, Haapasalo A, Hewitt AW, Vickers J, Smith GC, Oksanen M, Graff C, Kanninen KM, Lehtonen S, Propson N, Schwartz MP, Pébay A, Koistinaho J, Ooi L, Malm T.

Stem Cell Reports. 2019 Oct 8;13(4):669-683. doi: 10.1016/j.stemcr.2019.08.004. Epub 2019 Sep 12.


Modeling Emergent Properties in the Brain Using Tissue Models to Investigate Neurodegenerative Disease.

Harris AR, McGivern P, Ooi L.

Neuroscientist. 2019 Sep 13:1073858419870446. doi: 10.1177/1073858419870446. [Epub ahead of print]


Minimally-invasive versus open enucleation for pancreatic tumours: A propensity-score adjusted analysis.

Kabir T, Tan ZZX, Syn N, Chung AYF, Ooi LLPJ, Goh BKP.

Ann Hepatobiliary Pancreat Surg. 2019 Aug;23(3):258-264. doi: 10.14701/ahbps.2019.23.3.258. Epub 2019 Aug 30.


Outcome of minimally-invasive versus open pancreatectomies for solid pseudopapillary neoplasms of the pancreas: A 2:1 matched case-control study.

Tan HL, Tan EK, Teo JY, Kam JH, Lee SY, Cheow PC, Jeyaraj PR, Chow PK, Chung AY, Ooi LL, Chan CY, Goh BKP.

Ann Hepatobiliary Pancreat Surg. 2019 Aug;23(3):252-257. doi: 10.14701/ahbps.2019.23.3.252. Epub 2019 Aug 30.


Generation and characterization of a human induced pluripotent stem cell line UOWi005-A from dermal fibroblasts derived from a CCNFS621G familial amyotrophic lateral sclerosis patient using mRNA reprogramming.

Bax M, Balez R, Muñoz SS, Do-Ha D, Stevens CH, Berg T, Cabral-da-Silva MC, Engel M, Nicholson G, Yang S, Blair IP, Ooi L.

Stem Cell Res. 2019 Oct;40:101530. doi: 10.1016/j.scr.2019.101530. Epub 2019 Aug 14.


Comprehensive analysis of transcriptome profiles in hepatocellular carcinoma.

Jin Y, Lee WY, Toh ST, Tennakoon C, Toh HC, Chow PK, Chung AY, Chong SS, Ooi LL, Sung WK, Lee CG.

J Transl Med. 2019 Aug 20;17(1):273. doi: 10.1186/s12967-019-2025-x.


Roles and Regulation of Long Noncoding RNAs in Hepatocellular Carcinoma.

Lim LJ, Wong SYS, Huang F, Lim S, Chong SS, Ooi LL, Kon OL, Lee CG.

Cancer Res. 2019 Oct 15;79(20):5131-5139. doi: 10.1158/0008-5472.CAN-19-0255. Epub 2019 Jul 23. Review.


Circulating microRNAs as Potential Diagnostic and Prognostic Biomarkers in Hepatocellular Carcinoma.

Jin Y, Wong YS, Goh BKP, Chan CY, Cheow PC, Chow PKH, Lim TKH, Goh GBB, Krishnamoorthy TL, Kumar R, Ng TP, Chong SS, Tan HH, Chung AYF, Ooi LLPJ, Chang JPE, Tan CK, Lee CGL.

Sci Rep. 2019 Jul 18;9(1):10464. doi: 10.1038/s41598-019-46872-8.


Loss of Cln5 leads to altered Gad1 expression and deficits in interneuron development in mice.

Singh Y, Leinonen H, Fazaludeen F, Jaronen M, Guest D, Buckley N, Byts N, Oksa P, Jalkanen K, Iqbal I, Huuskonen M, Savchenko E, Keksa-Goldsteine V, Chew S, Myllyharju J, Tanila H, Ooi L, Koistinaho J, Kanninen KM, Malm T.

Hum Mol Genet. 2019 Oct 1;28(19):3309-3322. doi: 10.1093/hmg/ddz165.


Preoperative Predictors Including the Role of Inflammatory Indices in Predicting Early Recurrence After Re-resection for Recurrent Hepatocellular Carcinoma.

Guo Y, Chua DW, Koh YX, Lee SY, Cheow PC, Kam JH, Teo JY, Chow PK, Chung AY, Ooi LL, Chan CY, Goh BKP.

World J Surg. 2019 Oct;43(10):2587-2594. doi: 10.1007/s00268-019-05051-6.


The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation.

Bax M, McKenna J, Do-Ha D, Stevens CH, Higginbottom S, Balez R, Cabral-da-Silva MEC, Farrawell NE, Engel M, Poronnik P, Yerbury JJ, Saunders DN, Ooi L.

Cells. 2019 Jun 13;8(6). pii: E581. doi: 10.3390/cells8060581.


Increased Tau Phosphorylation in Motor Neurons From Clinically Pure Sporadic Amyotrophic Lateral Sclerosis Patients.

Stevens CH, Guthrie NJ, van Roijen M, Halliday GM, Ooi L.

J Neuropathol Exp Neurol. 2019 Jul 1;78(7):605-614. doi: 10.1093/jnen/nlz041.


Antibiotic Use and Outcomes After Implementation of the Drug Resistance in Pneumonia Score in ED Patients With Community-Onset Pneumonia.

Webb BJ, Sorensen J, Mecham I, Buckel W, Ooi L, Jephson A, Dean NC.

Chest. 2019 Nov;156(5):843-851. doi: 10.1016/j.chest.2019.04.093. Epub 2019 May 8.


Low plasma vitamin D is associated with adverse colorectal cancer survival after surgical resection, independent of systemic inflammatory response.

Vaughan-Shaw PG, Zgaga L, Ooi LY, Theodoratou E, Timofeeva M, Svinti V, Walker M, O'Sullivan F, Ewing A, Johnston S, Din FVN, Campbell H, Farrington SM, Dunlop MG.

Gut. 2020 Jan;69(1):103-111. doi: 10.1136/gutjnl-2018-317922. Epub 2019 Apr 25.


Genome-wide CRISPR knockout screens identify NCAPG as an essential oncogene for hepatocellular carcinoma tumor growth.

Wang Y, Gao B, Tan PY, Handoko YA, Sekar K, Deivasigamani A, Seshachalam VP, OuYang HY, Shi M, Xie C, Goh BKP, Ooi LL, Man Hui K.

FASEB J. 2019 Aug;33(8):8759-8770. doi: 10.1096/fj.201802213RR. Epub 2019 Apr 25.


Impact of spontaneous rupture on the survival outcomes after liver resection for hepatocellular carcinoma: A propensity matched analysis comparing ruptured versus non-ruptured tumors.

Chua DW, Koh YX, Allen JC, Chan CY, Lee SY, Cheow PC, Jeyaraj P, Teo JY, Chow PK, Chung AY, Ooi LL, Goh BKP.

Eur J Surg Oncol. 2019 Sep;45(9):1652-1659. doi: 10.1016/j.ejso.2019.03.044. Epub 2019 Apr 9.


The metastability of the proteome of spinal motor neurons underlies their selective vulnerability in ALS.

Yerbury JJ, Ooi L, Blair IP, Ciryam P, Dobson CM, Vendruscolo M.

Neurosci Lett. 2019 Jun 21;704:89-94. doi: 10.1016/j.neulet.2019.04.001. Epub 2019 Apr 3.


Dynamic interplay between H-current and M-current controls motoneuron hyperexcitability in amyotrophic lateral sclerosis.

Buskila Y, Kékesi O, Bellot-Saez A, Seah W, Berg T, Trpceski M, Yerbury JJ, Ooi L.

Cell Death Dis. 2019 Apr 5;10(4):310. doi: 10.1038/s41419-019-1538-9.


External validation of the Japanese difficulty scoring system for minimally-invasive distal pancreatectomies.

Goh BKP, Kabir T, Koh YX, Teo JY, Lee SY, Kam JH, Cheow PC, Jeyaraj PR, Chow PKH, Ooi LLPJ, Chung AYF, Chan CY.

Am J Surg. 2019 Nov;218(5):967-971. doi: 10.1016/j.amjsurg.2019.03.012. Epub 2019 Mar 15.


Initial single institution experience with robotic biliary surgery and bilio-enteric anastomosis in southeast Asia.

Goh BKP, Low TY, Teo JY, Lee SY, Chan CY, Chung AYF, Ooi LLPJ.

ANZ J Surg. 2019 Apr;89(4):E142-E146. doi: 10.1111/ans.15135. Epub 2019 Mar 18.


Periventricular White Matter Abnormalities on Diffusion Tensor Imaging of Postural Instability Gait Disorder Parkinsonism.

Tan SYZ, Keong NCH, Selvan RMP, Li H, Ooi LQR, Tan EK, Chan LL.

AJNR Am J Neuroradiol. 2019 Apr;40(4):609-613. doi: 10.3174/ajnr.A5993. Epub 2019 Mar 14.


NUF2 is a valuable prognostic biomarker to predict early recurrence of hepatocellular carcinoma after surgical resection.

Wang Y, Tan PY, Handoko YA, Sekar K, Shi M, Xie C, Jiang XD, Dong QZ, Goh BKP, Ooi LL, Gao Z, Hui KM.

Int J Cancer. 2019 Aug 1;145(3):662-670. doi: 10.1002/ijc.32134. Epub 2019 Feb 4.


Novel dual-action prodrug triggers apoptosis in glioblastoma cells by releasing a glutathione quencher and lysine-specific histone demethylase 1A inhibitor.

Engel M, Gee YS, Cross D, Maccarone A, Heng B, Hulme A, Smith G, Guillemin GJ, Stringer BW, Hyland CJT, Ooi L.

J Neurochem. 2019 May;149(4):535-550. doi: 10.1111/jnc.14655. Epub 2019 Feb 3.


Laparoscopic Liver Resection Difficulty Score-a Validation Study.

Lee SY, Goh BKP, Sepideh G, Allen JC, Merkow RP, Teo JY, Chandra D, Koh YX, Tan EK, Kam JH, Cheow PC, Chow PKH, Ooi LLPJ, Chung AYF, D'Angelica MI, Jarnagin WR, Peter Kingham T, Chan CY.

J Gastrointest Surg. 2019 Mar;23(3):545-555. doi: 10.1007/s11605-018-4036-y. Epub 2018 Nov 12.


Pre-operative predictors of early recurrence/mortality including the role of inflammatory indices in patients undergoing partial hepatectomy for spontaneously ruptured hepatocellular carcinoma.

Chua DW, Koh YX, Liew YX, Chan CY, Lee SY, Cheow PC, Chow PK, Chung AY, Ooi LL, Goh BK.

J Surg Oncol. 2018 Dec;118(8):1227-1236. doi: 10.1002/jso.25281. Epub 2018 Nov 6.


Perioperative Outcomes of Laparoscopic Repeat Liver Resection for Recurrent HCC: Comparison with Open Repeat Liver Resection for Recurrent HCC and Laparoscopic Resection for Primary HCC.

Goh BKP, Syn N, Teo JY, Guo YX, Lee SY, Cheow PC, Chow PKH, Ooi LLPJ, Chung AYF, Chan CY.

World J Surg. 2019 Mar;43(3):878-885. doi: 10.1007/s00268-018-4828-y.


Viral-free generation and characterization of a human induced pluripotent stem cell line from dermal fibroblasts.

Engel M, Balez R, Muñoz SS, Cabral-da-Silva MC, Stevens CH, Bax M, Do-Ha D, Sidhu K, Sachdev P, Ooi L.

Stem Cell Res. 2018 Oct;32:135-138. doi: 10.1016/j.scr.2018.09.014. Epub 2018 Sep 19.


Sad, Scared, or Rejected? A Short-Term Longitudinal Study of the Predictors of Social Avoidance in Chinese Children.

Ding X, Coplan RJ, Deng X, Ooi LL, Li D, Sang B.

J Abnorm Child Psychol. 2019 Jul;47(7):1265-1276. doi: 10.1007/s10802-018-0476-9.


Understanding the Role of ApoE Fragments in Alzheimer's Disease.

Muñoz SS, Garner B, Ooi L.

Neurochem Res. 2019 Jun;44(6):1297-1305. doi: 10.1007/s11064-018-2629-1. Epub 2018 Sep 17. Review.


CDK1-mediated BCL9 phosphorylation inhibits clathrin to promote mitotic Wnt signalling.

Chen J, Rajasekaran M, Xia H, Kong SN, Deivasigamani A, Sekar K, Gao H, Swa HL, Gunaratne J, Ooi LL, Xie T, Hong W, Hui KM.

EMBO J. 2018 Oct 15;37(20). pii: e99395. doi: 10.15252/embj.201899395. Epub 2018 Sep 14.


A retrospective review of correlative radiological assessment and surgical exploration for hilar cholangiocarcinoma.

Chua D, Low A, Koh Y, Goh B, Cheow PC, Kam JH, Teo JY, Tan EK, Chung A, Ooi LL, Chan CY, Lee SY.

Ann Hepatobiliary Pancreat Surg. 2018 Aug;22(3):216-222. doi: 10.14701/ahbps.2018.22.3.216. Epub 2018 Aug 31.


Predictors of post-hepatectomy liver failure in patients undergoing extensive liver resections for hepatocellular carcinoma.

Chin KM, Allen JC, Teo JY, Kam JH, Tan EK, Koh Y, Goh KPB, Cheow PC, Raj P, Chow KHP, Chung YFA, Ooi LL, Chan CY, Lee SY.

Ann Hepatobiliary Pancreat Surg. 2018 Aug;22(3):185-196. doi: 10.14701/ahbps.2018.22.3.185. Epub 2018 Aug 31.


Generation and characterization of human induced pluripotent stem cell lines from a familial Alzheimer's disease PSEN1 A246E patient and a non-demented family member bearing wild-type PSEN1.

Muñoz SS, Balez R, Castro Cabral-da-Silva ME, Berg T, Engel M, Bax M, Do-Ha D, Stevens CH, Greenough M, Bush A, Ooi L.

Stem Cell Res. 2018 Aug;31:227-230. doi: 10.1016/j.scr.2018.08.006. Epub 2018 Aug 13.


Curvature contribution on anodic aluminium oxide pore formation: a detailed analytical study.

Tiong TY, Ooi L, Dee CF, Hamzah AA, Majlis BY.

Nanotechnology. 2018 Oct 26;29(43):435601. doi: 10.1088/1361-6528/aad884. Epub 2018 Aug 7.


Astrocytic modulation of cortical oscillations.

Bellot-Saez A, Cohen G, van Schaik A, Ooi L, W Morley J, Buskila Y.

Sci Rep. 2018 Aug 1;8(1):11565. doi: 10.1038/s41598-018-30003-w.


Perioperative Outcomes of Laparoscopic Minor Hepatectomy for Hepatocellular Carcinoma in the Elderly.

Goh BKP, Chua D, Syn N, Teo JY, Chan CY, Lee SY, Jeyaraj PR, Cheow PC, Chow PKH, Ooi LLPJ, Chung AYF.

World J Surg. 2018 Dec;42(12):4063-4069. doi: 10.1007/s00268-018-4741-4.


The mechanism of SO2 -induced stomatal closure differs from O3 and CO2 responses and is mediated by nonapoptotic cell death in guard cells.

Ooi L, Matsuura T, Munemasa S, Murata Y, Katsuhara M, Hirayama T, Mori IC.

Plant Cell Environ. 2019 Feb;42(2):437-447. doi: 10.1111/pce.13406. Epub 2018 Oct 3.


Changing trends and outcomes associated with the adoption of minimally invasive hepatectomy: a contemporary single-institution experience with 400 consecutive resections.

Goh BKP, Lee SY, Teo JY, Kam JH, Jeyaraj PR, Cheow PC, Chow PKH, Ooi LLPJ, Chung AYF, Chan CY.

Surg Endosc. 2018 Nov;32(11):4658-4665. doi: 10.1007/s00464-018-6310-1. Epub 2018 Jul 2.


Identification and High-Resolution Imaging of α-Tocopherol from Human Cells to Whole Animals by TOF-SIMS Tandem Mass Spectrometry.

Bruinen AL, Fisher GL, Balez R, van der Sar AM, Ooi L, Heeren RMA.

J Am Soc Mass Spectrom. 2018 Aug;29(8):1571-1581. doi: 10.1007/s13361-018-1979-x. Epub 2018 Jun 12.


Chronic Adolescent CDPPB Treatment Alters Short-Term, but not Long-Term, Glutamatergic Receptor Expression.

Lum JS, Millard SJ, Frank E, Matosin N, Huang XF, Ooi L, Newell KA.

Neurochem Res. 2018 Aug;43(8):1683-1691. doi: 10.1007/s11064-018-2584-x. Epub 2018 Jun 23.


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