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Items: 1 to 50 of 52

1.

Rosiglitazone reverses endothelial dysfunction but not remodeling of femoral artery in Zucker diabetic fatty rats.

Lu X, Guo X, Karathanasis SK, Zimmerman KM, Onyia JE, Peterson RG, Kassab GS.

Cardiovasc Diabetol. 2010 May 19;9:19. doi: 10.1186/1475-2840-9-19.

2.

Analysis of early changes in the articular cartilage transcriptisome in the rat meniscal tear model of osteoarthritis: pathway comparisons with the rat anterior cruciate transection model and with human osteoarthritic cartilage.

Wei T, Kulkarni NH, Zeng QQ, Helvering LM, Lin X, Lawrence F, Hale L, Chambers MG, Lin C, Harvey A, Ma YL, Cain RL, Oskins J, Carozza MA, Edmondson DD, Hu T, Miles RR, Ryan TP, Onyia JE, Mitchell PG.

Osteoarthritis Cartilage. 2010 Jul;18(7):992-1000. doi: 10.1016/j.joca.2010.04.012. Epub 2010 Apr 29.

3.

Calcitonin impairs the anabolic effect of PTH in young rats and stimulates expression of sclerostin by osteocytes.

Gooi JH, Pompolo S, Karsdal MA, Kulkarni NH, Kalajzic I, McAhren SH, Han B, Onyia JE, Ho PW, Gillespie MT, Walsh NC, Chia LY, Quinn JM, Martin TJ, Sims NA.

Bone. 2010 Jun;46(6):1486-97. doi: 10.1016/j.bone.2010.02.018. Epub 2010 Feb 24.

PMID:
20188226
4.

Evolutionary computation for discovery of composite transcription factor binding sites.

Fogel GB, Porto VW, Varga G, Dow ER, Craven AM, Powers DM, Harlow HB, Su EW, Onyia JE, Su C.

Nucleic Acids Res. 2008 Dec;36(21):e142. doi: 10.1093/nar/gkn738. Epub 2008 Oct 15.

5.

EphrinB2 regulation by PTH and PTHrP revealed by molecular profiling in differentiating osteoblasts.

Allan EH, Häusler KD, Wei T, Gooi JH, Quinn JM, Crimeen-Irwin B, Pompolo S, Sims NA, Gillespie MT, Onyia JE, Martin TJ.

J Bone Miner Res. 2008 Aug;23(8):1170-81. doi: 10.1359/jbmr.080324.

6.

Ghrelin octanoylation mediated by an orphan lipid transferase.

Gutierrez JA, Solenberg PJ, Perkins DR, Willency JA, Knierman MD, Jin Z, Witcher DR, Luo S, Onyia JE, Hale JE.

Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6320-5. doi: 10.1073/pnas.0800708105. Epub 2008 Apr 28.

7.

Analysis of pathway activity in primary tumors and NCI60 cell lines using gene expression profiling data.

Feng XD, Huang SG, Shou JY, Liao BR, Yingling JM, Ye X, Lin X, Gelbert LM, Su EW, Onyia JE, Li SY.

Genomics Proteomics Bioinformatics. 2007 Feb;5(1):15-24.

8.

Changes in osteoblast, chondrocyte, and adipocyte lineages mediate the bone anabolic actions of PTH and small molecule GSK-3 inhibitor.

Kulkarni NH, Wei T, Kumar A, Dow ER, Stewart TR, Shou J, N'cho M, Sterchi DL, Gitter BD, Higgs RE, Halladay DL, Engler TA, Martin TJ, Bryant HU, Ma YL, Onyia JE.

J Cell Biochem. 2007 Dec 15;102(6):1504-18.

PMID:
17520664
9.

DNA microarray data integration by ortholog gene analysis reveals potential molecular mechanisms of estrogen-dependent growth of human uterine fibroids.

Wei T, Geiser AG, Qian HR, Su C, Helvering LM, Kulkarini NH, Shou J, N'Cho M, Bryant HU, Onyia JE.

BMC Womens Health. 2007 Apr 2;7:5.

10.

A proteomic analysis of adult rat bone reveals the presence of cartilage/chondrocyte markers.

Schreiweis MA, Butler JP, Kulkarni NH, Knierman MD, Higgs RE, Halladay DL, Onyia JE, Hale JE.

J Cell Biochem. 2007 May 15;101(2):466-76.

PMID:
17205546
11.
12.

Orally bioavailable GSK-3alpha/beta dual inhibitor increases markers of cellular differentiation in vitro and bone mass in vivo.

Kulkarni NH, Onyia JE, Zeng Q, Tian X, Liu M, Halladay DL, Frolik CA, Engler T, Wei T, Kriauciunas A, Martin TJ, Sato M, Bryant HU, Ma YL.

J Bone Miner Res. 2006 Jun;21(6):910-20.

13.

Identification of blood biomarkers of rheumatoid arthritis by transcript profiling of peripheral blood mononuclear cells from the rat collagen-induced arthritis model.

Shou J, Bull CM, Li L, Qian HR, Wei T, Luo S, Perkins D, Solenberg PJ, Tan SL, Chen XY, Roehm NW, Wolos JA, Onyia JE.

Arthritis Res Ther. 2006;8(1):R28. Epub 2006 Jan 10.

14.

Optimized blood cell profiling method for genomic biomarker discovery using high-density microarray.

Shou J, Dotson C, Qian HR, Tao W, Lin C, Lawrence F, N'Cho M, Kulkarni NH, Bull CM, Gelbert LM, Onyia JE.

Biomarkers. 2005 Jul-Aug;10(4):310-20.

PMID:
16191486
15.

Expression profiling of rat femur revealed suppression of bone formation genes by treatment with alendronate and estrogen but not raloxifene.

Helvering LM, Liu R, Kulkarni NH, Wei T, Chen P, Huang S, Lawrence F, Halladay DL, Miles RR, Ambrose EM, Sato M, Ma YL, Frolik CA, Dow ER, Bryant HU, Onyia JE.

Mol Pharmacol. 2005 Nov;68(5):1225-38. Epub 2005 Aug 3.

PMID:
16079270
16.

Data-driven analysis approach for biomarker discovery using molecular-profiling technologies.

Wei T, Liao B, Ackermann BL, Jolly RA, Eckstein JA, Kulkarni NH, Helvering LM, Goldstein KM, Shou J, Estrem ST, Ryan TP, Colet JM, Thomas CE, Stevens JL, Onyia JE.

Biomarkers. 2005 Mar-Jun;10(2-3):153-72.

PMID:
16076730
17.

Effects of parathyroid hormone on Wnt signaling pathway in bone.

Kulkarni NH, Halladay DL, Miles RR, Gilbert LM, Frolik CA, Galvin RJ, Martin TJ, Gillespie MT, Onyia JE.

J Cell Biochem. 2005 Aug 15;95(6):1178-90.

PMID:
15962290
18.

A statistical analysis of the TRANSFAC database.

Fogel GB, Weekes DG, Varga G, Dow ER, Craven AM, Harlow HB, Su EW, Onyia JE, Su C.

Biosystems. 2005 Aug;81(2):137-54.

PMID:
15941617
19.

Optimization and validation of small quantity RNA profiling for identifying TNF responses in cultured human vascular endothelial cells.

Shou J, Qian HR, Lin X, Stewart T, Onyia JE, Gelbert LM.

J Pharmacol Toxicol Methods. 2006 Mar-Apr;53(2):152-9.

PMID:
15878830
20.

Molecular profile of catabolic versus anabolic treatment regimens of parathyroid hormone (PTH) in rat bone: an analysis by DNA microarray.

Onyia JE, Helvering LM, Gelbert L, Wei T, Huang S, Chen P, Dow ER, Maran A, Zhang M, Lotinun S, Lin X, Halladay DL, Miles RR, Kulkarni NH, Ambrose EM, Ma YL, Frolik CA, Sato M, Bryant HU, Turner RT.

J Cell Biochem. 2005 May 15;95(2):403-18.

PMID:
15779007
21.

Differential effects of estrogen and raloxifene on messenger RNA and matrix metalloproteinase 2 activity in the rat uterus.

Helvering LM, Adrian MD, Geiser AG, Estrem ST, Wei T, Huang S, Chen P, Dow ER, Calley JN, Dodge JA, Grese TA, Jones SA, Halladay DL, Miles RR, Onyia JE, Ma YL, Sato M, Bryant HU.

Biol Reprod. 2005 Apr;72(4):830-41. Epub 2004 Dec 1.

PMID:
15576828
22.

Discovery of sequence motifs related to coexpression of genes using evolutionary computation.

Fogel GB, Weekes DG, Varga G, Dow ER, Harlow HB, Onyia JE, Su C.

Nucleic Acids Res. 2004 Jul 20;32(13):3826-35. Print 2004.

23.

Novel and selective small molecule stimulators of osteoprotegerin expression inhibit bone resorption.

Onyia JE, Galvin RJ, Ma YL, Halladay DL, Miles RR, Yang X, Fuson T, Cain RL, Zeng QQ, Chandrasekhar S, Emkey R, Xu Y, Thirunavukkarasu K, Bryant HU, Martin TJ.

J Pharmacol Exp Ther. 2004 Apr;309(1):369-79. Epub 2004 Jan 12.

PMID:
14718597
24.

Analysis of regulator of G-protein signaling-2 (RGS-2) expression and function in osteoblastic cells.

Thirunavukkarasu K, Halladay DL, Miles RR, Geringer CD, Onyia JE.

J Cell Biochem. 2002;85(4):837-50.

PMID:
11968023
25.

Parathyroid hormone (hPTH 1-38) stimulates the expression of UBP41, an ubiquitin-specific protease, in bone.

Miles RR, Sluka JP, Halladay DL, Santerre RF, Hale LV, Bloem L, Patanjali SR, Galvin RJ, Ma L, Hock JM, Onyia JE.

J Cell Biochem. 2002;85(2):229-42.

PMID:
11948679
26.

DNA binding and gene activation properties of the Nmp4 nuclear matrix transcription factors.

Torrungruang K, Alvarez M, Shah R, Onyia JE, Rhodes SJ, Bidwell JP.

J Biol Chem. 2002 May 3;277(18):16153-9. Epub 2002 Feb 26.

27.

Protein Kinase C is a mediator of the synthesis and secretion of osteoprotegerin in osteoblast-like cells.

Yang X, Halladay D, Onyia JE, Martin TJ, Chandrasekhar S.

Biochem Biophys Res Commun. 2002 Jan 11;290(1):42-6.

PMID:
11779130
28.

Identification of signal transduction pathways and promoter sequences that mediate parathyroid hormone 1-38 inhibition of osteoprotegerin gene expression.

Halladay DL, Miles RR, Thirunavukkarasu K, Chandrasekhar S, Martin TJ, Onyia JE.

J Cell Biochem. 2001;84(1):1-11.

PMID:
11746511
29.

Parathyroid hormone (1-34) regulates integrin expression in vivo in rat osteoblasts.

Kaiser E, Sato M, Onyia JE, Chandrasekhar S.

J Cell Biochem. 2001;83(4):617-30.

PMID:
11746505
30.

Catabolic effects of continuous human PTH (1--38) in vivo is associated with sustained stimulation of RANKL and inhibition of osteoprotegerin and gene-associated bone formation.

Ma YL, Cain RL, Halladay DL, Yang X, Zeng Q, Miles RR, Chandrasekhar S, Martin TJ, Onyia JE.

Endocrinology. 2001 Sep;142(9):4047-54.

PMID:
11517184
31.

Stimulation of osteoprotegerin (OPG) gene expression by transforming growth factor-beta (TGF-beta). Mapping of the OPG promoter region that mediates TGF-beta effects.

Thirunavukkarasu K, Miles RR, Halladay DL, Yang X, Galvin RJ, Chandrasekhar S, Martin TJ, Onyia JE.

J Biol Chem. 2001 Sep 28;276(39):36241-50. Epub 2001 Jul 12.

32.

Osteoblast apoptosis and bone turnover.

Hock JM, Krishnan V, Onyia JE, Bidwell JP, Milas J, Stanislaus D.

J Bone Miner Res. 2001 Jun;16(6):975-84. Review.

33.

Cloning and functional analysis of a family of nuclear matrix transcription factors (NP/NMP4) that regulate type I collagen expression in osteoblasts.

Thunyakitpisal P, Alvarez M, Tokunaga K, Onyia JE, Hock J, Ohashi N, Feister H, Rhodes SJ, Bidwell JP.

J Bone Miner Res. 2001 Jan;16(1):10-23.

34.

ADAMTS-1: A cellular disintegrin and metalloprotease with thrombospondin motifs is a target for parathyroid hormone in bone.

Miles RR, Sluka JP, Halladay DL, Santerre RF, Hale LV, Bloem L, Thirunavukkarasu K, Galvin RJ, Hock JM, Onyia JE.

Endocrinology. 2000 Dec;141(12):4533-42.

PMID:
11108265
35.

In vivo regulation of apoptosis in metaphyseal trabecular bone of young rats by synthetic human parathyroid hormone (1-34) fragment.

Stanislaus D, Yang X, Liang JD, Wolfe J, Cain RL, Onyia JE, Falla N, Marder P, Bidwell JP, Queener SW, Hock JM.

Bone. 2000 Aug;27(2):209-18.

PMID:
10913913
36.

The osteoblast-specific transcription factor Cbfa1 contributes to the expression of osteoprotegerin, a potent inhibitor of osteoclast differentiation and function.

Thirunavukkarasu K, Halladay DL, Miles RR, Yang X, Galvin RJ, Chandrasekhar S, Martin TJ, Onyia JE.

J Biol Chem. 2000 Aug 18;275(33):25163-72.

37.

In vivo demonstration that human parathyroid hormone 1-38 inhibits the expression of osteoprotegerin in bone with the kinetics of an immediate early gene.

Onyia JE, Miles RR, Yang X, Halladay DL, Hale J, Glasebrook A, McClure D, Seno G, Churgay L, Chandrasekhar S, Martin TJ.

J Bone Miner Res. 2000 May;15(5):863-71.

38.

Cryptic enhancer elements in luciferase reporter vectors respond to the osteoblast-specific transcription factor Osf2/Cbfa1.

Thirunavukkarasu K, Miles RR, Halladay DL, Onyia JE.

Biotechniques. 2000 Mar;28(3):506-10.

39.

The expression of the nuclear matrix proteins NuMA, topoisomerase II-alpha, and -beta in bone and osseous cell culture: regulation by parathyroid hormone.

Feister HA, Onyia JE, Miles RR, Yang X, Galvin R, Hock JM, Bidwell JP.

Bone. 2000 Mar;26(3):227-34.

PMID:
10709994
40.

Activation of osteocalcin transcription involves interaction of protein kinase A- and protein kinase C-dependent pathways.

Boguslawski G, Hale LV, Yu XP, Miles RR, Onyia JE, Santerre RF, Chandrasekhar S.

J Biol Chem. 2000 Jan 14;275(2):999-1006.

41.

Dynamic regulation of RGS2 in bone: potential new insights into parathyroid hormone signaling mechanisms.

Miles RR, Sluka JP, Santerre RF, Hale LV, Bloem L, Boguslawski G, Thirunavukkarasu K, Hock JM, Onyia JE.

Endocrinology. 2000 Jan;141(1):28-36.

PMID:
10614620
42.

Immunohistochemical localization of selected early response genes expressed in trabecular bone of young rats given hPTH 1-34.

Liang JD, Hock JM, Sandusky GE, Santerre RF, Onyia JE.

Calcif Tissue Int. 1999 Nov;65(5):369-73.

PMID:
10541762
43.

Molecular characterization of gene expression changes in ROS 17/2.8 cells cultured in diffusion chambers in vivo.

Onyia JE, Hale LV, Miles RR, Cain RL, Tu Y, Hulman JF, Hock JM, Santerre RF.

Calcif Tissue Int. 1999 Aug;65(2):133-8.

PMID:
10430646
44.

Intermittent administration of parathyroid hormone (1-34) stimulates matrix metalloproteinase-9 (MMP-9) expression in rat long bone.

McClelland P, Onyia JE, Miles RR, Tu Y, Liang J, Harvey AK, Chandrasekhar S, Hock JM, Bidwell JP.

J Cell Biochem. 1998 Sep 1;70(3):391-401.

PMID:
9706876
45.

Analysis of differential gene expression in rat tibia after an osteogenic stimulus in vivo: mechanical loading regulates osteopontin and myeloperoxidase.

Miles RR, Turner CH, Santerre R, Tu Y, McClelland P, Argot J, DeHoff BS, Mundy CW, Rosteck PR Jr, Bidwell J, Sluka JP, Hock J, Onyia JE.

J Cell Biochem. 1998 Mar 1;68(3):355-65.

PMID:
9518261
46.

Osteoprogenitor cells as targets for ex vivo gene transfer.

Onyia JE, Clapp DW, Long H, Hock JM.

J Bone Miner Res. 1998 Jan;13(1):20-30.

47.

Parathyroid hormone (1-34)-mediated interleukin-6 induction.

Onyia JE, Libermann TA, Bidwell J, Arnold D, Tu Y, McClelland P, Hock JM.

J Cell Biochem. 1997 Nov 1;67(2):265-74.

PMID:
9328832
48.

Mechanotransduction in bone: osteoblasts are more responsive to fluid forces than mechanical strain.

Owan I, Burr DB, Turner CH, Qiu J, Tu Y, Onyia JE, Duncan RL.

Am J Physiol. 1997 Sep;273(3 Pt 1):C810-5.

PMID:
9316399
49.

Proliferating cells in the primary spongiosa express osteoblastic phenotype in vitro.

Onyia JE, Miller B, Hulman J, Liang J, Galvin R, Frolik C, Chandrasekhar S, Harvey AK, Bidwell J, Herring J, Hock JM.

Bone. 1997 Feb;20(2):93-100.

PMID:
9028532

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