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Items: 27

1.

Revealing phenotype-associated functional differences by genome-wide scan of ancient haplotype blocks.

Onuki R, Yamaguchi R, Shibuya T, Kanehisa M, Goto S.

PLoS One. 2017 Apr 26;12(4):e0176530. doi: 10.1371/journal.pone.0176530. eCollection 2017.

2.

Acidic mammalian chitinase is a proteases-resistant glycosidase in mouse digestive system.

Ohno M, Kimura M, Miyazaki H, Okawa K, Onuki R, Nemoto C, Tabata E, Wakita S, Kashimura A, Sakaguchi M, Sugahara Y, Nukina N, Bauer PO, Oyama F.

Sci Rep. 2016 Nov 24;6:37756. doi: 10.1038/srep37756.

3.

Next-generation survey sequencing and the molecular organization of wheat chromosome 6B.

Tanaka T, Kobayashi F, Joshi GP, Onuki R, Sakai H, Kanamori H, Wu J, Simkova H, Nasuda S, Endo TR, Hayakawa K, Dole┼żel J, Ogihara Y, Itoh T, Matsumoto T, Handa H.

DNA Res. 2014;21(2):103-14. doi: 10.1093/dnares/dst041. Epub 2013 Oct 1.

4.

Population model-based inter-diplotype similarity measure for accurate diplotype clustering.

Onuki R, Yamada R, Yamaguchi R, Kanehisa M, Shibuya T.

J Comput Biol. 2012 Jan;19(1):55-67. doi: 10.1089/cmb.2010.0227. Epub 2011 Dec 9.

PMID:
22149683
5.

New kernel methods for phenotype prediction from genotype data.

Onuki R, Shibuya T, Kanehisa M.

Genome Inform. 2010 Jan;22:132-41.

6.

Construction of triple-transfected cells [organic anion-transporting polypeptide (OATP) 1B1/multidrug resistance-associated protein (MRP) 2/MRP3 and OATP1B1/MRP2/MRP4] for analysis of the sinusoidal function of MRP3 and MRP4.

Hirouchi M, Kusuhara H, Onuki R, Ogilvie BW, Parkinson A, Sugiyama Y.

Drug Metab Dispos. 2009 Oct;37(10):2103-11. doi: 10.1124/dmd.109.027193. Epub 2009 Jul 23.

PMID:
19628752
7.

Point-contact spectroscopy of the heavy-fermion superconductor CePt(3)Si.

Onuki R, Sumiyama A, Oda Y, Yasuda T, Settai R, Onuki Y.

J Phys Condens Matter. 2009 Feb 18;21(7):075703. doi: 10.1088/0953-8984/21/7/075703. Epub 2009 Jan 20.

PMID:
21817336
8.

Ezrin and radixin both regulate the apical membrane localization of ABCC2 (MRP2) in human intestinal epithelial Caco-2 cells.

Yang Q, Onuki R, Nakai C, Sugiyama Y.

Exp Cell Res. 2007 Oct 1;313(16):3517-25. Epub 2007 Aug 7.

PMID:
17825285
9.

Phosphorylated PKR contributes the induction of GRP94 under ER stress.

Ito M, Onuki R, Bando Y, Tohyama M, Sugiyama Y.

Biochem Biophys Res Commun. 2007 Aug 31;360(3):615-20. Epub 2007 Jun 26.

PMID:
17612505
10.

Retraction: Identification of genes that function in the TNF-alpha-mediated apoptotic pathway using randomized hybrid ribozyme libraries.

Onuki R, Suyama E, Taira K.

Nat Biotechnol. 2006 Sep;24(9):1170. No abstract available.

PMID:
16964231
11.

Inhibition of bile acid transport across Na+/taurocholate cotransporting polypeptide (SLC10A1) and bile salt export pump (ABCB 11)-coexpressing LLC-PK1 cells by cholestasis-inducing drugs.

Mita S, Suzuki H, Akita H, Hayashi H, Onuki R, Hofmann AF, Sugiyama Y.

Drug Metab Dispos. 2006 Sep;34(9):1575-81. Epub 2006 Jun 7.

PMID:
16760228
12.

Vectorial transport of unconjugated and conjugated bile salts by monolayers of LLC-PK1 cells doubly transfected with human NTCP and BSEP or with rat Ntcp and Bsep.

Mita S, Suzuki H, Akita H, Hayashi H, Onuki R, Hofmann AF, Sugiyama Y.

Am J Physiol Gastrointest Liver Physiol. 2006 Mar;290(3):G550-6.

13.

Transport by vesicles of glycine- and taurine-conjugated bile salts and taurolithocholate 3-sulfate: a comparison of human BSEP with rat Bsep.

Hayashi H, Takada T, Suzuki H, Onuki R, Hofmann AF, Sugiyama Y.

Biochim Biophys Acta. 2005 Dec 30;1738(1-3):54-62. Epub 2005 Nov 15.

PMID:
16332456
14.

Construction of a functional transporter analysis system using MDR1 knockdown Caco-2 cells.

Watanabe T, Onuki R, Yamashita S, Taira K, Sugiyama Y.

Pharm Res. 2005 Aug;22(8):1287-93. Epub 2005 Aug 3.

PMID:
16078138
15.

Lack of improvement of oral absorption of ME3277 by prodrug formation is ascribed to the intestinal efflux mediated by breast cancer resistant protein (BCRP/ABCG2).

Kondo C, Onuki R, Kusuhara H, Suzuki H, Suzuki M, Okudaira N, Kojima M, Ishiwata K, Jonker JW, Sugiyama Y.

Pharm Res. 2005 Apr;22(4):613-8. Epub 2005 Apr 7.

PMID:
15846469
16.

Double-strand RNA dependent protein kinase (PKR) is involved in the extrastriatal degeneration in Parkinson's disease and Huntington's disease.

Bando Y, Onuki R, Katayama T, Manabe T, Kudo T, Taira K, Tohyama M.

Neurochem Int. 2005 Jan;46(1):11-8.

PMID:
15567511
17.

An RNA-dependent protein kinase is involved in tunicamycin-induced apoptosis and Alzheimer's disease.

Onuki R, Bando Y, Suyama E, Katayama T, Kawasaki H, Baba T, Tohyama M, Taira K.

EMBO J. 2004 Feb 25;23(4):959-68. Epub 2004 Feb 5.

18.

[Visualization of activated caspase 8 using fluorescent resonance energy transfer (FRET)].

Onuki R, Nagasaki A, Taira K.

Tanpakushitsu Kakusan Koso. 2003 Aug;48(11 Suppl):1573-7. Review. Japanese. No abstract available.

PMID:
12931615
19.

A functional gene discovery in cell differentiation by hybrid ribozyme and siRNA libraries.

Kawasaki H, Tsunemi M, Iyo M, Oshima K, Minoshima H, Hamada A, Onuki R, Suyama E, Taira K.

Nucleic Acids Res Suppl. 2002;(2):275-6.

PMID:
12903211
20.

Use of Bid-ribozymes to characterize and Bid-affiliated apoptotic pathway.

Onuki R, Kawasaki H, Baba T, Taira K.

Nucleic Acids Res Suppl. 2001;(1):63-4.

PMID:
12836265
21.

Analysis of a mitochondrial apoptotic pathway using Bid-targeted ribozymes in human MCF7 cells in the absence of a caspase-3-dependent pathway.

Onuki R, Kawasaki H, Baba T, Taira K.

Antisense Nucleic Acid Drug Dev. 2003 Apr;13(2):75-82.

PMID:
12804035
22.

[Gene discovery system with randomized ribozyme libraries].

Suyama E, Kawasaki H, Onuki R, Taira K.

Tanpakushitsu Kakusan Koso. 2003 Mar;48(4 Suppl):532-9. Review. Japanese. No abstract available.

PMID:
12696164
23.

Developmental regulation of the proteolysis of the p35 cyclin-dependent kinase 5 activator by phosphorylation.

Saito T, Onuki R, Fujita Y, Kusakawa G, Ishiguro K, Bibb JA, Kishimoto T, Hisanaga S.

J Neurosci. 2003 Feb 15;23(4):1189-97.

24.

Confirmation by FRET in individual living cells of the absence of significant amyloid beta -mediated caspase 8 activation.

Onuki R, Nagasaki A, Kawasaki H, Baba T, Uyeda TQ, Taira K.

Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):14716-21. Epub 2002 Oct 30.

26.

Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25.

Kusakawa G, Saito T, Onuki R, Ishiguro K, Kishimoto T, Hisanaga S.

J Biol Chem. 2000 Jun 2;275(22):17166-72.

27.

Okadaic acid-stimulated degradation of p35, an activator of CDK5, by proteasome in cultured neurons.

Saito T, Ishiguro K, Onuki R, Nagai Y, Kishimoto T, Hisanaga S.

Biochem Biophys Res Commun. 1998 Nov 27;252(3):775-8.

PMID:
9837783

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