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Items: 1 to 50 of 65

1.

Highly Multiplexed Fluorescence in Situ Hybridization for in Situ Genomics.

Onozato ML, Yapp C, Richardson D, Sundaresan T, Chahal V, Lee J, Sullivan JP, Madden MW, Shim HS, Liebers M, Ho Q, Maheswaran S, Haber DA, Zheng Z, Clancy B, Elliott HL, Lennerz JK, Iafrate AJ.

J Mol Diagn. 2019 May;21(3):390-407. doi: 10.1016/j.jmoldx.2019.01.010. Epub 2019 Mar 9.

PMID:
30862547
2.

Genetically distinct glioma stem-like cell xenografts established from paired glioblastoma samples harvested before and after molecularly targeted therapy.

Tanaka S, Luk S, Kiyokawa J, Onozato ML, Iafrate AJ, Shah K, Martuza RL, Rabkin SD, Batchelor TT, Cahill DP, Chi AS, Wakimoto H.

Sci Rep. 2019 Jan 15;9(1):139. doi: 10.1038/s41598-018-37437-2.

3.

Expressed Gene Fusions as Frequent Drivers of Poor Outcomes in Hormone Receptor-Positive Breast Cancer.

Matissek KJ, Onozato ML, Sun S, Zheng Z, Schultz A, Lee J, Patel K, Jerevall PL, Saladi SV, Macleay A, Tavallai M, Badovinac-Crnjevic T, Barrios C, Beşe N, Chan A, Chavarri-Guerra Y, Debiasi M, Demirdögen E, Egeli Ü, Gökgöz S, Gomez H, Liedke P, Tasdelen I, Tolunay S, Werutsky G, St Louis J, Horick N, Finkelstein DM, Le LP, Bardia A, Goss PE, Sgroi DC, Iafrate AJ, Ellisen LW.

Cancer Discov. 2018 Mar;8(3):336-353. doi: 10.1158/2159-8290.CD-17-0535. Epub 2017 Dec 14.

4.

Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq.

Venteicher AS, Tirosh I, Hebert C, Yizhak K, Neftel C, Filbin MG, Hovestadt V, Escalante LE, Shaw ML, Rodman C, Gillespie SM, Dionne D, Luo CC, Ravichandran H, Mylvaganam R, Mount C, Onozato ML, Nahed BV, Wakimoto H, Curry WT, Iafrate AJ, Rivera MN, Frosch MP, Golub TR, Brastianos PK, Getz G, Patel AP, Monje M, Cahill DP, Rozenblatt-Rosen O, Louis DN, Bernstein BE, Regev A, Suvà ML.

Science. 2017 Mar 31;355(6332). pii: eaai8478. doi: 10.1126/science.aai8478.

5.

Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma.

Tirosh I, Venteicher AS, Hebert C, Escalante LE, Patel AP, Yizhak K, Fisher JM, Rodman C, Mount C, Filbin MG, Neftel C, Desai N, Nyman J, Izar B, Luo CC, Francis JM, Patel AA, Onozato ML, Riggi N, Livak KJ, Gennert D, Satija R, Nahed BV, Curry WT, Martuza RL, Mylvaganam R, Iafrate AJ, Frosch MP, Golub TR, Rivera MN, Getz G, Rozenblatt-Rosen O, Cahill DP, Monje M, Bernstein BE, Louis DN, Regev A, Suvà ML.

Nature. 2016 Nov 10;539(7628):309-313. doi: 10.1038/nature20123. Epub 2016 Nov 2.

6.

HER2 expression identifies dynamic functional states within circulating breast cancer cells.

Jordan NV, Bardia A, Wittner BS, Benes C, Ligorio M, Zheng Y, Yu M, Sundaresan TK, Licausi JA, Desai R, O'Keefe RM, Ebright RY, Boukhali M, Sil S, Onozato ML, Iafrate AJ, Kapur R, Sgroi D, Ting DT, Toner M, Ramaswamy S, Haas W, Maheswaran S, Haber DA.

Nature. 2016 Sep 1;537(7618):102-106. doi: 10.1038/nature19328. Epub 2016 Aug 24.

7.

Pan-cancer analysis of copy number changes in programmed death-ligand 1 (PD-L1, CD274) - associations with gene expression, mutational load, and survival.

Budczies J, Bockmayr M, Denkert C, Klauschen F, Gröschel S, Darb-Esfahani S, Pfarr N, Leichsenring J, Onozato ML, Lennerz JK, Dietel M, Fröhling S, Schirmacher P, Iafrate AJ, Weichert W, Stenzinger A.

Genes Chromosomes Cancer. 2016 Aug;55(8):626-39. doi: 10.1002/gcc.22365. Epub 2016 May 30.

PMID:
27106868
8.

Myc-Driven Glycolysis Is a Therapeutic Target in Glioblastoma.

Tateishi K, Iafrate AJ, Ho Q, Curry WT, Batchelor TT, Flaherty KT, Onozato ML, Lelic N, Sundaram S, Cahill DP, Chi AS, Wakimoto H.

Clin Cancer Res. 2016 Sep 1;22(17):4452-65. doi: 10.1158/1078-0432.CCR-15-2274. Epub 2016 Apr 13.

9.

Dendritic Cells in Kidney Transplant Biopsy Samples Are Associated with T Cell Infiltration and Poor Allograft Survival.

Batal I, De Serres SA, Safa K, Bijol V, Ueno T, Onozato ML, Iafrate AJ, Herter JM, Lichtman AH, Mayadas TN, Guleria I, Rennke HG, Najafian N, Chandraker A.

J Am Soc Nephrol. 2015 Dec;26(12):3102-13. doi: 10.1681/ASN.2014080804. Epub 2015 Apr 8.

10.

Impaired EphA4 signaling leads to congenital hydronephrosis, renal injury, and hypertension.

Sällström J, Peuckert C, Gao X, Larsson E, Nilsson A, Jensen BL, Onozato ML, Persson AE, Kullander K, Carlström M.

Am J Physiol Renal Physiol. 2013 Jul 1;305(1):F71-9. doi: 10.1152/ajprenal.00694.2012. Epub 2013 May 1.

11.

Pathology informatics fellowship retreats: The use of interactive scenarios and case studies as pathology informatics teaching tools.

Lee RE, McClintock DS, Balis UJ, Baron JM, Becich MJ, Beckwith BA, Brodsky VB, Carter AB, Dighe AS, Haghighi M, Hipp JD, Henricks WH, Kim JY, Klepseis VE, Kuo FC, Lane WJ, Levy BP, Onozato ML, Park SL, Sinard JH, Tuthill MJ, Gilbertson JR.

J Pathol Inform. 2012;3:41. doi: 10.4103/2153-3539.103995. Epub 2012 Nov 28.

12.

Tumor islands in resected early-stage lung adenocarcinomas are associated with unique clinicopathologic and molecular characteristics and worse prognosis.

Onozato ML, Kovach AE, Yeap BY, Morales-Oyarvide V, Klepeis VE, Tammireddy S, Heist RS, Mark EJ, Dias-Santagata D, Iafrate AJ, Yagi Y, Mino-Kenudson M.

Am J Surg Pathol. 2013 Feb;37(2):287-94. doi: 10.1097/PAS.0b013e31826885fb.

13.

A core curriculum for clinical fellowship training in pathology informatics.

McClintock DS, Levy BP, Lane WJ, Lee RE, Baron JM, Klepeis VE, Onozato ML, Kim J, Dighe AS, Beckwith BA, Kuo F, Black-Schaffer S, Gilbertson JR.

J Pathol Inform. 2012;3:31. Epub 2012 Aug 30.

14.

Different tracks for pathology informatics fellowship training: Experiences of and input from trainees in a large multisite fellowship program.

Levy BP, McClintock DS, Lee RE, Lane WJ, Klepeis VE, Baron JM, Onozato ML, Kim J, Brodsky V, Beckwith B, Kuo F, Gilbertson JR.

J Pathol Inform. 2012;3:30. Epub 2012 Aug 30.

15.

A role of three-dimensional (3D) reconstruction in the classification of lung adenocarcinoma.

Onozato ML, Klepeis VE, Yagi Y, Mino-Kenudson M.

Stud Health Technol Inform. 2012;179:250-6.

PMID:
22925805
16.

Evaluation of a completely automated tissue-sectioning machine for paraffin blocks.

Onozato ML, Hammond S, Merren M, Yagi Y.

Stud Health Technol Inform. 2012;179:233-8.

PMID:
22925803
17.

Effects of the antioxidant drug tempol on renal oxygenation in mice with reduced renal mass.

Lai EY, Luo Z, Onozato ML, Rudolph EH, Solis G, Jose PA, Wellstein A, Aslam S, Quinn MT, Griendling K, Le T, Li P, Palm F, Welch WJ, Wilcox CS.

Am J Physiol Renal Physiol. 2012 Jul 1;303(1):F64-74. doi: 10.1152/ajprenal.00005.2012. Epub 2012 Apr 4.

18.

A role of three-dimensional (3D)-reconstruction in the classification of lung adenocarcinoma.

Onozato ML, Klepeis VE, Yagi Y, Mino-Kenudson M.

Anal Cell Pathol (Amst). 2012;35(2):79-84. doi: 10.3233/ACP-2011-0030.

19.

Evaluation of a completely automated tissue-sectioning machine for paraffin blocks.

Onozato ML, Hammond S, Merren M, Yagi Y.

J Clin Pathol. 2013 Feb;66(2):151-4. doi: 10.1136/jclinpath-2011-200205. Epub 2011 Sep 7.

PMID:
21900334
20.

In vivo, label-free, three-dimensional quantitative imaging of kidney microcirculation using Doppler optical coherence tomography.

Wierwille J, Andrews PM, Onozato ML, Jiang J, Cable A, Chen Y.

Lab Invest. 2011 Nov;91(11):1596-604. doi: 10.1038/labinvest.2011.112. Epub 2011 Aug 1.

21.

Detection of myeloperoxidase in membranous nephropathy-like deposits in patients with anti-neutrophil cytoplasmic antibody-associated glomerulonephritis.

Hanamura K, Tojo A, Kinugasa S, Asaba K, Onozato ML, Uozaki H, Fukayama M, Fujita T.

Hum Pathol. 2011 May;42(5):649-58. doi: 10.1016/j.humpath.2010.08.020. Epub 2011 Feb 2.

PMID:
21292302
22.

Optical coherence tomography of human kidney.

Onozato ML, Andrews PM, Li Q, Jiang J, Cable A, Chen Y.

J Urol. 2010 May;183(5):2090-4. doi: 10.1016/j.juro.2009.12.091. Epub 2010 Mar 19.

PMID:
20303512
23.

Myogenic responses of mouse isolated perfused renal afferent arterioles: effects of salt intake and reduced renal mass.

Lai EY, Onozato ML, Solis G, Aslam S, Welch WJ, Wilcox CS.

Hypertension. 2010 Apr;55(4):983-9. doi: 10.1161/HYPERTENSIONAHA.109.149120. Epub 2010 Mar 1.

24.

Automated quantification of microstructural dimensions of the human kidney using optical coherence tomography (OCT).

Li Q, Onozato ML, Andrews PM, Chen CW, Paek A, Naphas R, Yuan S, Jiang J, Cable A, Chen Y.

Opt Express. 2009 Aug 31;17(18):16000-16. doi: 10.1364/OE.17.016000.

PMID:
19724599
25.

Long-term renal prognosis of IgA nephropathy with therapeutic trend shifts.

Asaba K, Tojo A, Onozato ML, Kinugasa S, Miyazaki H, Miyashita K, Uehara Y, Hirata Y, Kimura K, Goto A, Omata M, Fujita T.

Intern Med. 2009;48(11):883-90. Epub 2009 Jun 1.

26.

Rapid onset of diabetic nephropathy in three renal allografts despite normoglycemia.

Wojciechowski D, Onozato ML, Gonin J.

Clin Nephrol. 2009 Jun;71(6):719-24.

PMID:
19473643
27.

Glomerular albumin filtration through podocyte cell body in puromycin aminonucleoside nephrotic rat.

Tojo A, Onozato ML, Kitiyakara C, Kinugasa S, Fukuda S, Sakai T, Fujita T.

Med Mol Morphol. 2008 Jun;41(2):92-8. doi: 10.1007/s00795-008-0397-8. Epub 2008 Jul 1.

PMID:
18592163
28.

High-resolution optical coherence tomography imaging of the living kidney.

Andrews PM, Chen Y, Onozato ML, Huang SW, Adler DC, Huber RA, Jiang J, Barry SE, Cable AE, Fujimoto JG.

Lab Invest. 2008 Apr;88(4):441-9. doi: 10.1038/labinvest.2008.4. Epub 2008 Feb 11.

29.

Protective effect of dietary potassium against vascular injury in salt-sensitive hypertension.

Kido M, Ando K, Onozato ML, Tojo A, Yoshikawa M, Ogita T, Fujita T.

Hypertension. 2008 Feb;51(2):225-31. Epub 2007 Dec 24.

PMID:
18158352
30.

Dimethylarginine dimethylaminohydrolase (DDAH): expression, regulation, and function in the cardiovascular and renal systems.

Palm F, Onozato ML, Luo Z, Wilcox CS.

Am J Physiol Heart Circ Physiol. 2007 Dec;293(6):H3227-45. Epub 2007 Oct 12. Review.

31.
32.

Isoform-specific regulation by N(G),N(G)-dimethylarginine dimethylaminohydrolase of rat serum asymmetric dimethylarginine and vascular endothelium-derived relaxing factor/NO.

Wang D, Gill PS, Chabrashvili T, Onozato ML, Raggio J, Mendonca M, Dennehy K, Li M, Modlinger P, Leiper J, Vallance P, Adler O, Leone A, Tojo A, Welch WJ, Wilcox CS.

Circ Res. 2007 Sep 14;101(6):627-35. Epub 2007 Aug 2.

PMID:
17673667
33.

Suppressing renal NADPH oxidase to treat diabetic nephropathy.

Tojo A, Asaba K, Onozato ML.

Expert Opin Ther Targets. 2007 Aug;11(8):1011-8. Review.

PMID:
17665974
34.

Dual blockade of aldosterone and angiotensin II additively suppresses TGF-beta and NADPH oxidase in the hypertensive kidney.

Onozato ML, Tojo A, Kobayashi N, Goto A, Matsuoka H, Fujita T.

Nephrol Dial Transplant. 2007 May;22(5):1314-22. Epub 2007 Feb 26.

PMID:
17324946
35.

Double-edged action of SOD mimetic in diabetic nephropathy.

Asaba K, Tojo A, Onozato ML, Goto A, Fujita T.

J Cardiovasc Pharmacol. 2007 Jan;49(1):13-9.

PMID:
17261958
36.

Role of mouse organic anion transporter 3 (mOat3) as a basolateral prostaglandin E2 transport pathway.

Nilwarangkoon S, Anzai N, Shiraya K, Yu E, Islam R, Cha SH, Onozato ML, Miura D, Jutabha P, Tojo A, Kanai Y, Endou H.

J Pharmacol Sci. 2007 Jan;103(1):48-55. Epub 2007 Jan 13.

37.

Anti-carbonic anhydrase II antibody in autoimmune pancreatitis and tubulointerstitial nephritis.

Nishi H, Tojo A, Onozato ML, Jimbo R, Nangaku M, Uozaki H, Hirano K, Isayama H, Omata M, Kaname S, Fujita T.

Nephrol Dial Transplant. 2007 Apr;22(4):1273-5. Epub 2006 Nov 30. No abstract available. Erratum in: Nephrol Dial Transplant. 2007 May;22(5):1491. Fujita, Toshiro [added].

PMID:
17138573
38.

Spironolactone with ACE inhibitor is effective in gross hematuria caused by nephroptosis.

Tojo A, Onozato ML, Asaba K, Fujita T.

Int J Urol. 2006 Jul;13(7):990-2.

39.

Repeated subileus due to angioedema during renin-angiotensin system blockade.

Tojo A, Onozato ML, Fujita T.

Am J Med Sci. 2006 Jul;332(1):36-8.

PMID:
16845240
40.

Role of macula densa neuronal nitric oxide synthase in renal diseases.

Tojo A, Onozato ML, Fujita T.

Med Mol Morphol. 2006 Mar;39(1):2-7. Review.

PMID:
16575507
41.

A non-sulfated form of the HNK-1 carbohydrate is expressed in mouse kidney.

Tagawa H, Kizuka Y, Ikeda T, Itoh S, Kawasaki N, Kurihara H, Onozato ML, Tojo A, Sakai T, Kawasaki T, Oka S.

J Biol Chem. 2005 Jun 24;280(25):23876-83. Epub 2005 Apr 20.

42.

Effects of NADPH oxidase inhibitor in diabetic nephropathy.

Asaba K, Tojo A, Onozato ML, Goto A, Quinn MT, Fujita T, Wilcox CS.

Kidney Int. 2005 May;67(5):1890-8.

43.

Eplerenone shows renoprotective effect by reducing LOX-1-mediated adhesion molecule, PKCepsilon-MAPK-p90RSK, and Rho-kinase pathway.

Kobayashi N, Hara K, Tojo A, Onozato ML, Honda T, Yoshida K, Mita S, Nakano S, Tsubokou Y, Matsuoka H.

Hypertension. 2005 Apr;45(4):538-44. Epub 2005 Feb 14.

PMID:
15710785
44.

Antioxidative effect of p38 mitogen-activated protein kinase inhibitor in the kidney of hypertensive rat.

Tojo A, Onozato ML, Kobayashi N, Goto A, Matsuoka H, Fujita T.

J Hypertens. 2005 Jan;23(1):165-74.

PMID:
15643139
45.

Nitric oxide generated by nNOS in the macula densa regulates the afferent arteriolar diameter in rat kidney.

Tojo A, Onozato ML, Fukuda S, Asaba K, Kimura K, Fujita T.

Med Electron Microsc. 2004 Dec;37(4):236-41.

PMID:
15614448
46.

Human organic cation transporter 3 mediates the transport of antiarrhythmic drugs.

Hasannejad H, Takeda M, Narikawa S, Huang XL, Enomoto A, Taki K, Niwa T, Jung SH, Onozato ML, Tojo A, Endou H.

Eur J Pharmacol. 2004 Sep 19;499(1-2):45-51.

PMID:
15363950
47.

Radical scavenging effect of gliclazide in diabetic rats fed with a high cholesterol diet.

Onozato ML, Tojo A, Goto A, Fujita T.

Kidney Int. 2004 Mar;65(3):951-60.

48.

Endogenous adrenomedullin protects against vascular response to injury in mice.

Kawai J, Ando K, Tojo A, Shimosawa T, Takahashi K, Onozato ML, Yamasaki M, Ogita T, Nakaoka T, Fujita T.

Circulation. 2004 Mar 9;109(9):1147-53. Epub 2004 Feb 9.

PMID:
14769703
49.

Expression of human organic anion transporters in the choroid plexus and their interactions with neurotransmitter metabolites.

Alebouyeh M, Takeda M, Onozato ML, Tojo A, Noshiro R, Hasannejad H, Inatomi J, Narikawa S, Huang XL, Khamdang S, Anzai N, Endou H.

J Pharmacol Sci. 2003 Dec;93(4):430-6.

50.

Evidence for a role of human organic anion transporters in the muscular side effects of HMG-CoA reductase inhibitors.

Takeda M, Noshiro R, Onozato ML, Tojo A, Hasannejad H, Huang XL, Narikawa S, Endou H.

Eur J Pharmacol. 2004 Jan 12;483(2-3):133-8.

PMID:
14729100

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