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Maternal Lutein and Zeaxanthin Concentrations in Relation to Offspring Visual Acuity at 3 Years of Age: The GUSTO Study.

Lai JS, Veetil VO, Lanca C, Lee BL, Godfrey KM, Gluckman PD, Shek LP, Yap F, Tan KH, Chong YS, Ong CN, Ngo CS, Saw SM, Chong MFF.

Nutrients. 2020 Jan 21;12(2). pii: E274. doi: 10.3390/nu12020274.


Lomatogonium Rotatum for Treatment of Acute Liver Injury in Mice: A Metabolomics Study.

Chen R, Wang Q, Zhao L, Yang S, Li Z, Feng Y, Chen J, Ong CN, Zhang H.

Metabolites. 2019 Oct 14;9(10). pii: E227. doi: 10.3390/metabo9100227.


Toxicity Study of Zinc Oxide Nanoparticles in Cell Culture and in Drosophila melanogaster.

Ng CT, Ong CN, Yu LE, Bay BH, Baeg GH.

J Vis Exp. 2019 Sep 19;(151). doi: 10.3791/59510.


Association between maternal carotenoid, vitamin A, and vitamin E levels and allergic outcomes in the offspring in the first 5 years of life.

Loo EXL, Zhu Y, Lai JS, Chan YH, Ong CN, Tham EH, Goh A, Teoh OH, Tan KH, Yap F, Chong YS, Gluckman PD, Godfrey KM, Van Bever H, Lee BW, Chong MF, Shek LP.

Pediatr Allergy Immunol. 2020 Jan;31(1):95-97. doi: 10.1111/pai.13122. Epub 2019 Oct 9. No abstract available.


Association between serum heavy metals and prostate cancer risk - A multiple metal analysis.

Lim JT, Tan YQ, Valeri L, Lee J, Geok PP, Chia SE, Ong CN, Seow WJ.

Environ Int. 2019 Nov;132:105109. doi: 10.1016/j.envint.2019.105109. Epub 2019 Sep 3.


Simultaneous Quantification of 22 Glucosinolates in 12 Brassicaceae Vegetables by Hydrophilic Interaction Chromatography-Tandem Mass Spectrometry.

Liang X, Lee HW, Li Z, Lu Y, Zou L, Ong CN.

ACS Omega. 2018 Nov 15;3(11):15546-15553. doi: 10.1021/acsomega.8b01668. eCollection 2018 Nov 30.


Male-biased zebrafish sex differentiation and metabolomics profile changes caused by dydrogesterone.

Jiang YX, Shi WJ, Ma DD, Zhang JN, Ying GG, Zhang H, Ong CN.

Aquat Toxicol. 2019 Sep;214:105242. doi: 10.1016/j.aquatox.2019.105242. Epub 2019 Jul 11.


Targeted metabolomics reveals differential biological effects of nanoplastics and nanoZnO in human lung cells.

Lim SL, Ng CT, Zou L, Lu Y, Chen J, Bay BH, Shen HM, Ong CN.

Nanotoxicology. 2019 Oct;13(8):1117-1132. doi: 10.1080/17435390.2019.1640913. Epub 2019 Jul 24.


Dydrogesterone exposure induces zebrafish ovulation but leads to oocytes over-ripening: An integrated histological and metabolomics study.

Jiang YX, Shi WJ, Ma DD, Zhang JN, Ying GG, Zhang H, Ong CN.

Environ Int. 2019 Jul;128:390-398. doi: 10.1016/j.envint.2019.04.059. Epub 2019 May 9.


Employing multi-omics to elucidate the hormetic response against oxidative stress exerted by nC60 on Daphnia pulex.

Wang P, Ng QX, Zhang B, Wei Z, Hassan M, He Y, Ong CN.

Environ Pollut. 2019 Aug;251:22-29. doi: 10.1016/j.envpol.2019.04.097. Epub 2019 Apr 30.


Impacts of peat-forest smoke on urban PM2.5 in the Maritime Continent during 2012-2015: Carbonaceous profiles and indicators.

Tham J, Sarkar S, Jia S, Reid JS, Mishra S, Sudiana IM, Swarup S, Ong CN, Yu LE.

Environ Pollut. 2019 May;248:496-505. doi: 10.1016/j.envpol.2019.02.049. Epub 2019 Feb 20.


Metabolic signatures of four major histological types of lung cancer cells.

Lim SL, Jia Z, Lu Y, Zhang H, Ng CT, Bay BH, Shen HM, Ong CN.

Metabolomics. 2018 Aug 31;14(9):118. doi: 10.1007/s11306-018-1417-x.


Reproducibility of Dietary Biomarkers in a Multiethnic Asian Population.

Whitton C, Neelakantan N, Ong CN, van Dam RM.

Mol Nutr Food Res. 2019 Apr;63(8):e1801104. doi: 10.1002/mnfr.201801104. Epub 2019 Mar 7.


Serum Amino Acids in Association with Prevalent and Incident Type 2 Diabetes in A Chinese Population.

Lu Y, Wang Y, Liang X, Zou L, Ong CN, Yuan JM, Koh WP, Pan A.

Metabolites. 2019 Jan 14;9(1). pii: E14. doi: 10.3390/metabo9010014.


Use of an integrated metabolomics platform for mechanistic investigations of three commonly used algaecides on cyanobacterium, Microcystis aeruginosa.

Zhang H, Meng G, Mao F, Li W, He Y, Gin KY, Ong CN.

J Hazard Mater. 2019 Apr 5;367:120-127. doi: 10.1016/j.jhazmat.2018.12.069. Epub 2018 Dec 19.


Characterization of Plant Volatiles Reveals Distinct Metabolic Profiles and Pathways among 12 Brassicaceae Vegetables.

Liu Y, Zhang H, Umashankar S, Liang X, Lee HW, Swarup S, Ong CN.

Metabolites. 2018 Dec 14;8(4). pii: E94. doi: 10.3390/metabo8040094.


Metabolites change of Scenedesmus obliquus exerted by AgNPs.

Wang P, Zhang B, Zhang H, He Y, Ong CN, Yang J.

J Environ Sci (China). 2019 Feb;76:310-318. doi: 10.1016/j.jes.2018.05.017. Epub 2018 May 25.


The use of Drosophila melanogaster as a model organism to study immune-nanotoxicity.

Ng CT, Yu LE, Ong CN, Bay BH, Baeg GH.

Nanotoxicology. 2019 May;13(4):429-446. doi: 10.1080/17435390.2018.1546413. Epub 2018 Nov 19. Review.


Occurrence and distribution of pesticides in precipitation as revealed by targeted screening through GC-MS/MS.

Zhang H, Watts S, Philix MC, Snyder SA, Ong CN.

Chemosphere. 2018 Nov;211:210-217. doi: 10.1016/j.chemosphere.2018.07.151. Epub 2018 Jul 26.


Metabolite changes behind faster growth and less reproduction of Daphnia similis exposed to low-dose silver nanoparticles.

Wang P, Ng QX, Zhang H, Zhang B, Ong CN, He Y.

Ecotoxicol Environ Saf. 2018 Nov 15;163:266-273. doi: 10.1016/j.ecoenv.2018.07.080. Epub 2018 Jul 26.


Detection of Lung Cancer: Concomitant Volatile Organic Compounds and Metabolomic Profiling of Six Cancer Cell Lines of Different Histological Origins.

Jia Z, Zhang H, Ong CN, Patra A, Lu Y, Lim CT, Venkatesan T.

ACS Omega. 2018 May 31;3(5):5131-5140. doi: 10.1021/acsomega.7b02035. Epub 2018 May 10.


Plasma fatty acids and risk of colon and rectal cancers in the Singapore Chinese Health Study.

Butler LM, Yuan JM, Huang JY, Su J, Wang R, Koh WP, Ong CN.

NPJ Precis Oncol. 2017 Nov 23;1(1):38. doi: 10.1038/s41698-017-0040-z. eCollection 2017.


Profiling of Phenolic Compounds and Antioxidant Activity of 12 Cruciferous Vegetables.

Li Z, Lee HW, Liang X, Liang D, Wang Q, Huang D, Ong CN.

Molecules. 2018 May 10;23(5). pii: E1139. doi: 10.3390/molecules23051139.


Comparison of hepatic and serum lipid signatures in hepatocellular carcinoma patients leads to the discovery of diagnostic and prognostic biomarkers.

Lu Y, Chen J, Huang C, Li N, Zou L, Chia SE, Chen S, Yu K, Ling Q, Cheng Q, Zhu M, Zhang W, Chen M, Ong CN.

Oncotarget. 2017 Dec 13;9(4):5032-5043. doi: 10.18632/oncotarget.23494. eCollection 2018 Jan 12.


Omega-6-derived oxylipin changes in serum of patients with hepatitis B virus-related liver diseases.

Lu Y, Fang J, Zou L, Cui L, Liang X, Lim SG, Dan YY, Ong CN.

Metabolomics. 2018 Jan 31;14(3):26. doi: 10.1007/s11306-018-1326-z.


Serum metabolome changes in adult patients with severe dengue in the critical and recovery phases of dengue infection.

Cui L, Pang J, Lee YH, Ooi EE, Ong CN, Leo YS, Tannenbaum SR.

PLoS Negl Trop Dis. 2018 Jan 24;12(1):e0006217. doi: 10.1371/journal.pntd.0006217. eCollection 2018 Jan.


Serum Lipids in Association With Type 2 Diabetes Risk and Prevalence in a Chinese Population.

Lu Y, Wang Y, Zou L, Liang X, Ong CN, Tavintharan S, Yuan JM, Koh WP, Pan A.

J Clin Endocrinol Metab. 2018 Feb 1;103(2):671-680. doi: 10.1210/jc.2017-02176. Erratum in: J Clin Endocrinol Metab. 2020 Jan 1;105(1):.


Profiling of Plasma Metabolites Suggests Altered Mitochondrial Fuel Usage and Remodeling of Sphingolipid Metabolism in Individuals With Type 2 Diabetes and Kidney Disease.

Liu JJ, Ghosh S, Kovalik JP, Ching J, Choi HW, Tavintharan S, Ong CN, Sum CF, Summers SA, Tai ES, Lim SC.

Kidney Int Rep. 2016 Dec 16;2(3):470-480. doi: 10.1016/j.ekir.2016.12.003. eCollection 2017 May.


Relative Validity and Reproducibility of a Food Frequency Questionnaire for Assessing Dietary Intakes in a Multi-Ethnic Asian Population Using 24-h Dietary Recalls and Biomarkers.

Whitton C, Ho JCY, Tay Z, Rebello SA, Lu Y, Ong CN, van Dam RM.

Nutrients. 2017 Sep 25;9(10). pii: E1059. doi: 10.3390/nu9101059.


Meat and Seafood Consumption in Relation to Plasma Metabolic Profiles in a Chinese Population: A Combined Untargeted and Targeted Metabolomics Study.

Lu Y, Zou L, Su J, Tai ES, Whitton C, Dam RMV, Ong CN.

Nutrients. 2017 Jun 30;9(7). pii: E683. doi: 10.3390/nu9070683.


Serum Metabolomics Investigation of Humanized Mouse Model of Dengue Virus Infection.

Cui L, Hou J, Fang J, Lee YH, Costa VV, Wong LH, Chen Q, Ooi EE, Tannenbaum SR, Chen J, Ong CN.

J Virol. 2017 Jun 26;91(14). pii: e00386-17. doi: 10.1128/JVI.00386-17. Print 2017 Jul 15.


Biomedical Applications of Nanomaterials as Therapeutics.

Ng CT, Baeg GH, Yu LE, Ong CN, Bay BH.

Curr Med Chem. 2018;25(12):1409-1419. doi: 10.2174/0929867324666170331120328. Review.


Biological effect of aqueous C60 aggregates on Scenedesmus obliquus revealed by transcriptomics and non-targeted metabolomics.

Du C, Zhang B, He Y, Hu C, Ng QX, Zhang H, Ong CN, ZhifenLin.

J Hazard Mater. 2017 Feb 15;324(Pt B):221-229. doi: 10.1016/j.jhazmat.2016.10.052. Epub 2016 Oct 22.


Zinc oxide nanoparticles exhibit cytotoxicity and genotoxicity through oxidative stress responses in human lung fibroblasts and Drosophila melanogaster.

Ng CT, Yong LQ, Hande MP, Ong CN, Yu LE, Bay BH, Baeg GH.

Int J Nanomedicine. 2017 Feb 28;12:1621-1637. doi: 10.2147/IJN.S124403. eCollection 2017.


Metabolic responses of the growing Daphnia similis to chronic AgNPs exposure as revealed by GC-Q-TOF/MS and LC-Q-TOF/MS.

Zhang B, Zhang H, Du C, Ng QX, Hu C, He Y, Ong CN.

Water Res. 2017 May 1;114:135-143. doi: 10.1016/j.watres.2017.02.046. Epub 2017 Feb 20.


Consumption of Red Meat, but Not Cooking Oils High in Polyunsaturated Fat, Is Associated with Higher Arachidonic Acid Status in Singapore Chinese Adults.

Seah JY, Gay GM, Su J, Tai ES, Yuan JM, Koh WP, Ong CN, van Dam RM.

Nutrients. 2017 Jan 31;9(2). pii: E101. doi: 10.3390/nu9020101.


Dietary predictors and plasma concentrations of perfluorinated alkyl acids in a Singapore population.

Liu Y, Su J, van Dam RM, Prem K, Hoong JYS, Zou L, Lu Y, Ong CN.

Chemosphere. 2017 Mar;171:617-624. doi: 10.1016/j.chemosphere.2016.12.107. Epub 2016 Dec 26.


Metabolic signatures and risk of type 2 diabetes in a Chinese population: an untargeted metabolomics study using both LC-MS and GC-MS.

Lu Y, Wang Y, Ong CN, Subramaniam T, Choi HW, Yuan JM, Koh WP, Pan A.

Diabetologia. 2016 Nov;59(11):2349-2359. doi: 10.1007/s00125-016-4069-2. Epub 2016 Aug 11.


Plasma fatty acids, oxylipins, and risk of myocardial infarction: the Singapore Chinese Health Study.

Sun Y, Koh HW, Choi H, Koh WP, Yuan JM, Newman JW, Su J, Fang J, Ong CN, van Dam RM.

J Lipid Res. 2016 Jul;57(7):1300-7. doi: 10.1194/jlr.P066423. Epub 2016 May 24.


Metabolomics Investigation Reveals Metabolite Mediators Associated with Acute Lung Injury and Repair in a Murine Model of Influenza Pneumonia.

Cui L, Zheng D, Lee YH, Chan TK, Kumar Y, Ho WE, Chen JZ, Tannenbaum SR, Ong CN.

Sci Rep. 2016 May 18;6:26076. doi: 10.1038/srep26076.


Gold nanocluster sensitized TiO2 nanotube arrays for visible-light driven photoelectrocatalytic removal of antibiotic tetracycline.

Liu Y, Yao Q, Wu X, Chen T, Ma Y, Ong CN, Xie J.

Nanoscale. 2016 May 21;8(19):10145-51. doi: 10.1039/c6nr01702a. Epub 2016 Apr 28.


Serum Metabolomics Reveals Serotonin as a Predictor of Severe Dengue in the Early Phase of Dengue Fever.

Cui L, Lee YH, Thein TL, Fang J, Pang J, Ooi EE, Leo YS, Ong CN, Tannenbaum SR.

PLoS Negl Trop Dis. 2016 Apr 7;10(4):e0004607. doi: 10.1371/journal.pntd.0004607. eCollection 2016 Apr.


Acetylcarnitine Is a Candidate Diagnostic and Prognostic Biomarker of Hepatocellular Carcinoma.

Lu Y, Li N, Gao L, Xu YJ, Huang C, Yu K, Ling Q, Cheng Q, Chen S, Zhu M, Fang J, Chen M, Ong CN.

Cancer Res. 2016 May 15;76(10):2912-20. doi: 10.1158/0008-5472.CAN-15-3199. Epub 2016 Mar 14.


Urine phyto-oestrogen metabolites are not significantly associated with risk of type 2 diabetes: the Singapore Chinese health study.

Talaei M, Lee BL, Ong CN, van Dam RM, Yuan JM, Koh WP, Pan A.

Br J Nutr. 2016 May;115(9):1607-15. doi: 10.1017/S0007114516000581. Epub 2016 Mar 7.


Plasma α-Linolenic and Long-Chain ω-3 Fatty Acids Are Associated with a Lower Risk of Acute Myocardial Infarction in Singapore Chinese Adults.

Sun Y, Koh WP, Yuan JM, Choi H, Su J, Ong CN, van Dam RM.

J Nutr. 2016 Feb;146(2):275-82. doi: 10.3945/jn.115.220418. Epub 2015 Nov 25.


A genome-wide association study of n-3 and n-6 plasma fatty acids in a Singaporean Chinese population.

Dorajoo R, Sun Y, Han Y, Ke T, Burger A, Chang X, Low HQ, Guan W, Lemaitre RN, Khor CC, Yuan JM, Koh WP, Ong CN, Tai ES, Liu J, van Dam RM, Heng CK, Friedlander Y.

Genes Nutr. 2015 Nov;10(6):53. doi: 10.1007/s12263-015-0502-2. Epub 2015 Nov 19.


Associations of serum organohalogen levels and prostate cancer risk: Results from a case-control study in Singapore.

Pi N, Chia SE, Ong CN, Kelly BC.

Chemosphere. 2016 Feb;144:1505-12. doi: 10.1016/j.chemosphere.2015.10.020. Epub 2015 Oct 23.


MicroRNAs as biomarkers of hepatotoxicity in a randomized placebo-controlled study of simvastatin and ubiquinol supplementation.

Pek SL, Tavintharan S, Woon K, Lin L, Ong CN, Lim SC, Sum CF.

Exp Biol Med (Maywood). 2016 Feb;241(3):317-30. doi: 10.1177/1535370215605588. Epub 2015 Sep 30.


Associations between Urinary Excretion of Cadmium and Renal Biomarkers in Nonsmoking Females: A Cross-Sectional Study in Rural Areas of South China.

Zhang YR, Wang P, Liang XX, Tan CS, Tan JB, Wang J, Huang Q, Huang R, Li ZX, Chen WC, Wu SX, Ong CN, Yang XF, Wu YN.

Int J Environ Res Public Health. 2015 Sep 24;12(10):11988-2001. doi: 10.3390/ijerph121011988.

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