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Items: 1 to 50 of 82

1.

Function of essential chloride and arginine residue in nucleotide binding to vesicular nucleotide transporter.

Iwai Y, Kamatani S, Moriyama S, Omote H.

J Biochem. 2019 Jun 1;165(6):479-486. doi: 10.1093/jb/mvz002.

PMID:
30649354
2.

Outward open conformation of a Major Facilitator Superfamily multidrug/H+ antiporter provides insights into switching mechanism.

Nagarathinam K, Nakada-Nakura Y, Parthier C, Terada T, Juge N, Jaenecke F, Liu K, Hotta Y, Miyaji T, Omote H, Iwata S, Nomura N, Stubbs MT, Tanabe M.

Nat Commun. 2018 Oct 1;9(1):4005. doi: 10.1038/s41467-018-06306-x.

3.

Purification and reconstitution of polyspecific H+/organic cation antiporter human MATE1.

Kawasaki T, Matsumoto T, Iwai Y, Kawakami M, Juge N, Omote H, Nabekura T, Moriyama Y.

Biochim Biophys Acta Biomembr. 2018 Nov;1860(11):2456-2464. doi: 10.1016/j.bbamem.2018.07.005. Epub 2018 Jul 17.

PMID:
30028956
4.

Vesicular nucleotide transporter mediates ATP release and migration in neutrophils.

Harada Y, Kato Y, Miyaji T, Omote H, Moriyama Y, Hiasa M.

J Biol Chem. 2018 Mar 9;293(10):3770-3779. doi: 10.1074/jbc.M117.810168. Epub 2018 Jan 23.

5.

Efficient Mass Spectral Analysis of Active Transporters Overexpressed in Escherichia coli.

Kawakami M, Juge N, Kato Y, Omote H, Moriyama Y, Miyaji T.

J Proteome Res. 2018 Mar 2;17(3):1108-1119. doi: 10.1021/acs.jproteome.7b00777. Epub 2018 Feb 5.

PMID:
29350038
6.

Reconstitution and Transport Analysis of Eukaryotic Transporters in the Post-Genomic Era.

Omote H, Moriyama Y.

Methods Mol Biol. 2018;1700:343-352. doi: 10.1007/978-1-4939-7454-2_19.

PMID:
29177840
7.

Identification of a vesicular ATP release inhibitor for the treatment of neuropathic and inflammatory pain.

Kato Y, Hiasa M, Ichikawa R, Hasuzawa N, Kadowaki A, Iwatsuki K, Shima K, Endo Y, Kitahara Y, Inoue T, Nomura M, Omote H, Moriyama Y, Miyaji T.

Proc Natl Acad Sci U S A. 2017 Jul 18. pii: 201704847. doi: 10.1073/pnas.1704847114. [Epub ahead of print]

8.

Vesicular nucleotide transporter (VNUT): appearance of an actress on the stage of purinergic signaling.

Moriyama Y, Hiasa M, Sakamoto S, Omote H, Nomura M.

Purinergic Signal. 2017 Sep;13(3):387-404. doi: 10.1007/s11302-017-9568-1. Epub 2017 Jun 14. Review.

9.

Function and expression of a splicing variant of vesicular glutamate transporter 1.

Moriyama S, Iharada M, Omote H, Moriyama Y, Hiasa M.

Biochim Biophys Acta Biomembr. 2017 May;1859(5):931-940. doi: 10.1016/j.bbamem.2017.02.002. Epub 2017 Feb 8.

10.

Vesicular Polyamine Transporter Mediates Vesicular Storage and Release of Polyamine from Mast Cells.

Takeuchi T, Harada Y, Moriyama S, Furuta K, Tanaka S, Miyaji T, Omote H, Moriyama Y, Hiasa M.

J Biol Chem. 2017 Mar 3;292(9):3909-3918. doi: 10.1074/jbc.M116.756197. Epub 2017 Jan 12.

11.

Structure, Function, and Drug Interactions of Neurotransmitter Transporters in the Postgenomic Era.

Omote H, Miyaji T, Hiasa M, Juge N, Moriyama Y.

Annu Rev Pharmacol Toxicol. 2016;56:385-402. doi: 10.1146/annurev-pharmtox-010814-124816. Epub 2015 Oct 22. Review.

PMID:
26514205
12.

Wide expression of type I Na+-phosphate cotransporter 3 (NPT3/SLC17A2), a membrane potential-driven organic anion transporter.

Togawa N, Juge N, Miyaji T, Hiasa M, Omote H, Moriyama Y.

Am J Physiol Cell Physiol. 2015 Jul 15;309(2):C71-80. doi: 10.1152/ajpcell.00048.2015. Epub 2015 May 13.

13.

Plasmodium falciparum chloroquine resistance transporter is a H+-coupled polyspecific nutrient and drug exporter.

Juge N, Moriyama S, Miyaji T, Kawakami M, Iwai H, Fukui T, Nelson N, Omote H, Moriyama Y.

Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):3356-61. doi: 10.1073/pnas.1417102112. Epub 2015 Mar 2.

14.

AtPHT4;4 is a chloroplast-localized ascorbate transporter in Arabidopsis.

Miyaji T, Kuromori T, Takeuchi Y, Yamaji N, Yokosho K, Shimazawa A, Sugimoto E, Omote H, Ma JF, Shinozaki K, Moriyama Y.

Nat Commun. 2015 Jan 5;6:5928. doi: 10.1038/ncomms6928.

15.

Identification of a mammalian vesicular polyamine transporter.

Hiasa M, Miyaji T, Haruna Y, Takeuchi T, Harada Y, Moriyama S, Yamamoto A, Omote H, Moriyama Y.

Sci Rep. 2014 Oct 30;4:6836. doi: 10.1038/srep06836.

16.

Impairment of vesicular ATP release affects glucose metabolism and increases insulin sensitivity.

Sakamoto S, Miyaji T, Hiasa M, Ichikawa R, Uematsu A, Iwatsuki K, Shibata A, Uneyama H, Takayanagi R, Yamamoto A, Omote H, Nomura M, Moriyama Y.

Sci Rep. 2014 Oct 21;4:6689. doi: 10.1038/srep06689.

17.

Involvement of the leaf-specific multidrug and toxic compound extrusion (MATE) transporter Nt-JAT2 in vacuolar sequestration of nicotine in Nicotiana tabacum.

Shitan N, Minami S, Morita M, Hayashida M, Ito S, Takanashi K, Omote H, Moriyama Y, Sugiyama A, Goossens A, Moriyasu M, Yazaki K.

PLoS One. 2014 Sep 30;9(9):e108789. doi: 10.1371/journal.pone.0108789. eCollection 2014.

18.

Oxidation and reduction processes of platinum nanoparticles observed at the atomic scale by environmental transmission electron microscopy.

Yoshida H, Omote H, Takeda S.

Nanoscale. 2014 Nov 7;6(21):13113-8. doi: 10.1039/c4nr04352a.

PMID:
25248870
19.

Essential role of vesicular nucleotide transporter in vesicular storage and release of nucleotides in platelets.

Hiasa M, Togawa N, Miyaji T, Omote H, Yamamoto A, Moriyama Y.

Physiol Rep. 2014 Jun 6;2(6). pii: e12034. doi: 10.14814/phy2.12034. Print 2014 Jun 1.

20.
21.

Inhibitors of ATP release inhibit vesicular nucleotide transporter.

Kato Y, Omote H, Miyaji T.

Biol Pharm Bull. 2013;36(11):1688-91.

22.

Vesicular GABA transporter (VGAT) transports β-alanine.

Juge N, Omote H, Moriyama Y.

J Neurochem. 2013 Nov;127(4):482-6. doi: 10.1111/jnc.12393. Epub 2013 Aug 27.

23.

Type 1 sodium-dependent phosphate transporter acts as a membrane potential-driven urate exporter.

Miyaji T, Kawasaki T, Togawa N, Omote H, Moriyama Y.

Curr Mol Pharmacol. 2013 Jul;6(2):88-94. Review.

PMID:
23876149
24.

Vesicular neurotransmitter transporters: an approach for studying transporters with purified proteins.

Omote H, Moriyama Y.

Physiology (Bethesda). 2013 Jan;28(1):39-50. doi: 10.1152/physiol.00033.2012. Review.

25.

A Na+-phosphate cotransporter homologue (SLC17A4 protein) is an intestinal organic anion exporter.

Togawa N, Miyaji T, Izawa S, Omote H, Moriyama Y.

Am J Physiol Cell Physiol. 2012 Jun 1;302(11):C1652-60. doi: 10.1152/ajpcell.00015.2012. Epub 2012 Mar 28.

26.

Divalent cation transport by vesicular nucleotide transporter.

Miyaji T, Sawada K, Omote H, Moriyama Y.

J Biol Chem. 2011 Dec 16;286(50):42881-7. doi: 10.1074/jbc.M111.277269. Epub 2011 Nov 3.

27.

Functional characterization of vesicular excitatory amino acid transport by human sialin.

Miyaji T, Omote H, Moriyama Y.

J Neurochem. 2011 Oct;119(1):1-5. doi: 10.1111/j.1471-4159.2011.07388.x. Epub 2011 Aug 22.

28.

Vesicular neurotransmitter transporter: bioenergetics and regulation of glutamate transport.

Omote H, Miyaji T, Juge N, Moriyama Y.

Biochemistry. 2011 Jun 28;50(25):5558-65. doi: 10.1021/bi200567k. Epub 2011 Jun 2. Review.

PMID:
21612282
29.

Characterization of the human MATE2 proton-coupled polyspecific organic cation exporter.

Komatsu T, Hiasa M, Miyaji T, Kanamoto T, Matsumoto T, Otsuka M, Moriyama Y, Omote H.

Int J Biochem Cell Biol. 2011 Jun;43(6):913-8. doi: 10.1016/j.biocel.2011.03.005. Epub 2011 Mar 17.

PMID:
21419862
30.

A vesicular transporter that mediates aspartate and glutamate neurotransmission.

Miyaji T, Omote H, Moriyama Y.

Biol Pharm Bull. 2010;33(11):1783-5.

31.

Metabolic control of vesicular glutamate transport and release.

Juge N, Gray JA, Omote H, Miyaji T, Inoue T, Hara C, Uneyama H, Edwards RH, Nicoll RA, Moriyama Y.

Neuron. 2010 Oct 6;68(1):99-112. doi: 10.1016/j.neuron.2010.09.002.

32.

Type 1 sodium-dependent phosphate transporter (SLC17A1 Protein) is a Cl(-)-dependent urate exporter.

Iharada M, Miyaji T, Fujimoto T, Hiasa M, Anzai N, Omote H, Moriyama Y.

J Biol Chem. 2010 Aug 20;285(34):26107-13. doi: 10.1074/jbc.M110.122721. Epub 2010 Jun 21.

33.

Tricks of the trade used to accelerate high-resolution structure determination of membrane proteins.

Sonoda Y, Cameron A, Newstead S, Omote H, Moriyama Y, Kasahara M, Iwata S, Drew D.

FEBS Lett. 2010 Jun 18;584(12):2539-47. doi: 10.1016/j.febslet.2010.04.015. Epub 2010 Apr 13. Review.

34.

Vesicular inhibitory amino acid transporter is a Cl-/gamma-aminobutyrate Co-transporter.

Juge N, Muroyama A, Hiasa M, Omote H, Moriyama Y.

J Biol Chem. 2009 Dec 11;284(50):35073-8. doi: 10.1074/jbc.M109.062414. Epub 2009 Oct 20.

35.

[Localization mechanism of vesicular neurotransmitter transporters].

Omote H, Moriyama Y.

Tanpakushitsu Kakusan Koso. 2008 Dec;53(16 Suppl):2220-4. Review. Japanese. No abstract available.

PMID:
21038612
36.

Vesicular glutamate transporter acts as a metabolic regulator.

Moriyama Y, Omote H.

Biol Pharm Bull. 2008 Oct;31(10):1844-6. Review.

37.

Identification of a vesicular aspartate transporter.

Miyaji T, Echigo N, Hiasa M, Senoh S, Omote H, Moriyama Y.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11720-4. doi: 10.1073/pnas.0804015105. Epub 2008 Aug 11.

38.

Multidrug and toxic compound extrusion (MATE)-type proteins as anchor transporters for the excretion of metabolic waste products and xenobiotics.

Moriyama Y, Hiasa M, Matsumoto T, Omote H.

Xenobiotica. 2008 Jul;38(7-8):1107-18. doi: 10.1080/00498250701883753 . Review.

PMID:
18668441
39.

Identification of a vesicular nucleotide transporter.

Sawada K, Echigo N, Juge N, Miyaji T, Otsuka M, Omote H, Yamamoto A, Moriyama Y.

Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5683-6. doi: 10.1073/pnas.0800141105. Epub 2008 Mar 28.

40.

Role of glutamate residues in substrate recognition by human MATE1 polyspecific H+/organic cation exporter.

Matsumoto T, Kanamoto T, Otsuka M, Omote H, Moriyama Y.

Am J Physiol Cell Physiol. 2008 Apr;294(4):C1074-8. doi: 10.1152/ajpcell.00504.2007. Epub 2008 Feb 27.

41.

[Identification, structure and function of a drug transporter at the final step of extrusion].

Hiasa M, Omote H, Moriyama Y.

Tanpakushitsu Kakusan Koso. 2008 Jan;53(1):52-8. Review. Japanese. No abstract available.

PMID:
18186303
42.

[Molecular mechanism of vesicular glutamate transporter].

Omote H, Juge N.

Seikagaku. 2007 Oct;79(10):956-60. Review. Japanese. No abstract available.

PMID:
18027574
43.

A novel variant of mouse MATE-1 H+/organic cation antiporter with a long hydrophobic tail.

Kobara A, Hiasa M, Matsumoto T, Otsuka M, Omote H, Moriyama Y.

Arch Biochem Biophys. 2008 Jan 15;469(2):195-9. Epub 2007 Oct 25.

PMID:
17983590
44.

Functional characterization of testis-specific rodent multidrug and toxic compound extrusion 2, a class III MATE-type polyspecific H+/organic cation exporter.

Hiasa M, Matsumoto T, Komatsu T, Omote H, Moriyama Y.

Am J Physiol Cell Physiol. 2007 Nov;293(5):C1437-44. Epub 2007 Aug 22.

45.

Vesicular glutamate transporter contains two independent transport machineries.

Juge N, Yoshida Y, Yatsushiro S, Omote H, Moriyama Y.

J Biol Chem. 2006 Dec 22;281(51):39499-506. Epub 2006 Oct 17.

46.

The MATE proteins as fundamental transporters of metabolic and xenobiotic organic cations.

Omote H, Hiasa M, Matsumoto T, Otsuka M, Moriyama Y.

Trends Pharmacol Sci. 2006 Nov;27(11):587-93. Epub 2006 Sep 25.

PMID:
16996621
47.

Secretion of L-glutamate from osteoclasts through transcytosis.

Morimoto R, Uehara S, Yatsushiro S, Juge N, Hua Z, Senoh S, Echigo N, Hayashi M, Mizoguchi T, Ninomiya T, Udagawa N, Omote H, Yamamoto A, Edwards RH, Moriyama Y.

EMBO J. 2006 Sep 20;25(18):4175-86. Epub 2006 Sep 7.

48.

The remarkable transport mechanism of P-glycoprotein: a multidrug transporter.

Al-Shawi MK, Omote H.

J Bioenerg Biomembr. 2005 Dec;37(6):489-96. Review.

49.
50.

Examination of drug resistance activity of human TAP-like (ABCB9) expressed in yeast.

Ohashi-Kobayashi A, Ohashi K, Du WB, Omote H, Nakamoto R, Al-Shawi M, Maeda M.

Biochem Biophys Res Commun. 2006 May 5;343(2):597-601. Epub 2006 Mar 10.

PMID:
16554024

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