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Items: 8

1.

Specific Labeling of Stem Cell Activity in Human Colorectal Organoids Using an ASCL2-Responsive Minigene.

Oost KC, van Voorthuijsen L, Fumagalli A, Lindeboom RGH, Sprangers J, Omerzu M, Rodriguez-Colman MJ, Heinz MC, Verlaan-Klink I, Maurice MM, Burgering BMT, van Rheenen J, Vermeulen M, Snippert HJG.

Cell Rep. 2018 Feb 6;22(6):1600-1614. doi: 10.1016/j.celrep.2018.01.033.

2.

Mapping the Synthetic Dosage Lethality Network of CDK1/CDC28.

Zimmermann C, Garcia I, Omerzu M, Chymkowitch P, Zhang B, Enserink JM.

G3 (Bethesda). 2017 Jun 7;7(6):1753-1766. doi: 10.1534/g3.117.042317.

3.

Inhibition of the spindle assembly checkpoint kinase TTK enhances the efficacy of docetaxel in a triple-negative breast cancer model.

Maia AR, de Man J, Boon U, Janssen A, Song JY, Omerzu M, Sterrenburg JG, Prinsen MB, Willemsen-Seegers N, de Roos JA, van Doornmalen AM, Uitdehaag JC, Kops GJ, Jonkers J, Buijsman RC, Zaman GJ, Medema RH.

Ann Oncol. 2015 Oct;26(10):2180-92. doi: 10.1093/annonc/mdv293. Epub 2015 Jul 7.

PMID:
26153498
4.

Dissecting the roles of human BUB1 in the spindle assembly checkpoint.

Vleugel M, Hoek TA, Tromer E, Sliedrecht T, Groenewold V, Omerzu M, Kops GJ.

J Cell Sci. 2015 Aug 15;128(16):2975-82. doi: 10.1242/jcs.169821. Epub 2015 Jul 6.

5.

Sequential multisite phospho-regulation of KNL1-BUB3 interfaces at mitotic kinetochores.

Vleugel M, Omerzu M, Groenewold V, Hadders MA, Lens SMA, Kops GJPL.

Mol Cell. 2015 Mar 5;57(5):824-835. doi: 10.1016/j.molcel.2014.12.036. Epub 2015 Feb 5.

6.

Conditional targeting of MAD1 to kinetochores is sufficient to reactivate the spindle assembly checkpoint in metaphase.

Kuijt TE, Omerzu M, Saurin AT, Kops GJ.

Chromosoma. 2014 Oct;123(5):471-80. doi: 10.1007/s00412-014-0458-9. Epub 2014 Apr 4.

7.

Arrayed BUB recruitment modules in the kinetochore scaffold KNL1 promote accurate chromosome segregation.

Vleugel M, Tromer E, Omerzu M, Groenewold V, Nijenhuis W, Snel B, Kops GJ.

J Cell Biol. 2013 Dec 23;203(6):943-55.

8.

A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression.

Zimmermann C, Chymkowitch P, Eldholm V, Putnam CD, Lindvall JM, Omerzu M, Bjørås M, Kolodner RD, Enserink JM.

Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18748-53. doi: 10.1073/pnas.1115885108. Epub 2011 Oct 31.

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