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NIH Career Development Awards: conversion to research grants and regional distribution.

Conte ML, Omary MB.

J Clin Invest. 2018 Dec 3;128(12):5187-5190. doi: 10.1172/JCI123875. Epub 2018 Oct 29. No abstract available.


A transportome-scale amiRNA-based screen identifies redundant roles of Arabidopsis ABCB6 and ABCB20 in auxin transport.

Zhang Y, Nasser V, Pisanty O, Omary M, Wulff N, Di Donato M, Tal I, Hauser F, Hao P, Roth O, Fromm H, Schroeder JI, Geisler M, Nour-Eldin HH, Shani E.

Nat Commun. 2018 Oct 11;9(1):4204. doi: 10.1038/s41467-018-06410-y.


Loss of hepatocyte β-catenin protects mice from experimental porphyria-associated liver injury.

Saggi H, Maitra D, Jiang A, Zhang R, Wang P, Cornuet P, Singh S, Locker J, Ma X, Dailey H, Abrams M, Omary MB, Monga SP, Nejak-Bowen K.

J Hepatol. 2018 Oct 1. pii: S0168-8278(18)32442-5. doi: 10.1016/j.jhep.2018.09.023. [Epub ahead of print]


Hepatic NF-kB-inducing kinase (NIK) suppresses mouse liver regeneration in acute and chronic liver diseases.

Xiong Y, Torsoni AS, Wu F, Shen H, Liu Y, Zhong X, Canet MJ, Shah YM, Omary MB, Liu Y, Rui L.

Elife. 2018 Aug 2;7. pii: e34152. doi: 10.7554/eLife.34152.


Pancreatic HIF2α Stabilization Leads to Chronic Pancreatitis and Predisposes to Mucinous Cystic Neoplasm.

Schofield HK, Tandon M, Park MJ, Halbrook CJ, Ramakrishnan SK, Kim EC, Shi J, Omary MB, Shah YM, Esni F, Pasca di Magliano M.

Cell Mol Gastroenterol Hepatol. 2017 Nov 10;5(2):169-185.e2. doi: 10.1016/j.jcmgh.2017.10.008. eCollection 2018.


Types I and II Keratin Intermediate Filaments.

Jacob JT, Coulombe PA, Kwan R, Omary MB.

Cold Spring Harb Perspect Biol. 2018 Apr 2;10(4). pii: a018275. doi: 10.1101/cshperspect.a018275. Review.


Lamins and Lamin-Associated Proteins in Gastrointestinal Health and Disease.

Brady GF, Kwan R, Bragazzi Cunha J, Elenbaas JS, Omary MB.

Gastroenterology. 2018 May;154(6):1602-1619.e1. doi: 10.1053/j.gastro.2018.03.026. Epub 2018 Mar 13. Review.


The hepatic BMAL1/AKT/lipogenesis axis protects against alcoholic liver disease in mice via promoting PPARα pathway.

Zhang D, Tong X, Nelson BB, Jin E, Sit J, Charney N, Yang M, Omary MB, Yin L.

Hepatology. 2018 Mar 13. doi: 10.1002/hep.29878. [Epub ahead of print]


The sweet side of vimentin.

Snider NT, Ku NO, Omary MB.

Elife. 2018 Mar 7;7. pii: e35336. doi: 10.7554/eLife.35336.


Mechanistic Investigations of Photoinduced Oxygenation of Ru(II) Bis-bipyridyl Flavonolate Complexes.

Han X, Kumar MR, Hoogerbrugge A, Klausmeyer KK, Ghimire MM, Harris LM, Omary MA, Farmer PJ.

Inorg Chem. 2018 Mar 5;57(5):2416-2424. doi: 10.1021/acs.inorgchem.7b01384. Epub 2018 Feb 20.


HIF1-alpha Regulates Acinar Cell Function and Response to Injury in Mouse Pancreas.

Park MJ, Iyer S, Xue X, Bragazzi Cunha J, Gu S, Moons D, Pipe SW, Williams JA, Simeone DM, Shah YM, Omary MB.

Gastroenterology. 2018 May;154(6):1630-1634.e3. doi: 10.1053/j.gastro.2018.01.037. Epub 2018 Feb 1.


Lamin A/C Maintains Exocrine Pancreas Homeostasis by Regulating Stability of RB and Activity of E2F.

Elenbaas JS, Bragazzi Cunha J, Azuero-Dajud R, Nelson B, Oral EA, Williams JA, Stewart CL, Omary MB.

Gastroenterology. 2018 May;154(6):1625-1629.e8. doi: 10.1053/j.gastro.2018.01.024. Epub 2018 Jan 31.


An OLTAM system for analysis of brown/beige fat thermogenic activity.

Kim DI, Liao J, Emont MP, Park MJ, Jun H, Ramakrishnan SK, Lin JD, Shah YM, Omary MB, Wu J.

Int J Obes (Lond). 2018 Apr;42(4):939-945. doi: 10.1038/ijo.2017.308. Epub 2018 Jan 23.


A Phosphorescent Trinuclear Gold(I) Pyrazolate Chemosensor for Silver Ion Detection and Remediation in Aqueous Media.

Upadhyay PK, Marpu SB, Benton EN, Williams CL, Telang A, Omary MA.

Anal Chem. 2018 Apr 17;90(8):4999-5006. doi: 10.1021/acs.analchem.7b04334. Epub 2018 Mar 26.


Insights into Molecular Structures and Optical Properties of Stacked [Au3(RN═CR')3]n Complexes.

Rabaâ H, Omary MA, Taubert S, Sundholm D.

Inorg Chem. 2018 Jan 16;57(2):718-730. doi: 10.1021/acs.inorgchem.7b02593. Epub 2017 Dec 26.


Remarkable Aurophilicity and Photoluminescence Thermochromism in a Homoleptic Cyclic Trinuclear Gold(I) Imidazolate Complex.

Ghimire MM, Nesterov VN, Omary MA.

Inorg Chem. 2017 Oct 16;56(20):12086-12089. doi: 10.1021/acs.inorgchem.7b01679. Epub 2017 Sep 28.


Hepatocyte-Specific Deletion of Mouse Lamin A/C Leads to Male-Selective Steatohepatitis.

Kwan R, Brady GF, Brzozowski M, Weerasinghe SV, Martin H, Park MJ, Brunt MJ, Menon RK, Tong X, Yin L, Stewart CL, Omary MB.

Cell Mol Gastroenterol Hepatol. 2017 Jul 6;4(3):365-383. doi: 10.1016/j.jcmgh.2017.06.005. eCollection 2017 Nov.


Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease.

Brady GF, Kwan R, Ulintz PJ, Nguyen P, Bassirian S, Basrur V, Nesvizhskii AI, Loomba R, Omary MB.

Hepatology. 2018 May;67(5):1710-1725. doi: 10.1002/hep.29522. Epub 2018 Mar 24.


Thermo-mechanically responsive crystalline organic cantilever.

Dharmarwardana M, Welch RP, Kwon S, Nguyen VK, McCandless GT, Omary MA, Gassensmith JJ.

Chem Commun (Camb). 2017 Aug 22;53(71):9890-9893. doi: 10.1039/c7cc04346e.


Photochemical formation of chitosan-stabilized near-infrared-absorbing silver Nanoworms: A "Green" synthetic strategy and activity on Gram-negative pathogenic bacteria.

Marpu S, Kolailat SS, Korir D, Kamras BL, Chaturvedi R, Joseph A, Smith CM, Palma MC, Shah J, Omary MA.

J Colloid Interface Sci. 2017 Dec 1;507:437-452. doi: 10.1016/j.jcis.2017.08.009. Epub 2017 Aug 4.


Lipogenic transcription factor ChREBP mediates fructose-induced metabolic adaptations to prevent hepatotoxicity.

Zhang D, Tong X, VanDommelen K, Gupta N, Stamper K, Brady GF, Meng Z, Lin J, Rui L, Omary MB, Yin L.

J Clin Invest. 2017 Jun 30;127(7):2855-2867. doi: 10.1172/JCI89934. Epub 2017 Jun 19.


Cupriphication of gold to sensitize d10-d10 metal-metal bonds and near-unity phosphorescence quantum yields.

Galassi R, Ghimire MM, Otten BM, Ricci S, McDougald RN Jr, Almotawa RM, Alhmoud D, Ivy JF, Rawashdeh AM, Nesterov VN, Reinheimer EW, Daniels LM, Burini A, Omary MA.

Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5042-E5051. doi: 10.1073/pnas.1700890114. Epub 2017 Jun 14.


Globalization and changing trends of biomedical research output.

Conte ML, Liu J, Schnell S, Omary MB.

JCI Insight. 2017 Jun 15;2(12). pii: 95206. doi: 10.1172/jci.insight.95206. [Epub ahead of print]


Adsorption and molecular siting of CO2, water, and other gases in the superhydrophobic, flexible pores of FMOF-1 from experiment and simulation.

Moghadam PZ, Ivy JF, Arvapally RK, Dos Santos AM, Pearson JC, Zhang L, Tylianakis E, Ghosh P, Oswald IWH, Kaipa U, Wang X, Wilson AK, Snurr RQ, Omary MA.

Chem Sci. 2017 May 1;8(5):3989-4000. doi: 10.1039/c7sc00278e. Epub 2017 Mar 10.


Intermediate filament proteins of digestive organs: physiology and pathophysiology.

Omary MB.

Am J Physiol Gastrointest Liver Physiol. 2017 Jun 1;312(6):G628-G634. doi: 10.1152/ajpgi.00455.2016. Epub 2017 Mar 30. Review.


Finely Resolved On-Road PM2.5 and Estimated Premature Mortality in Central North Carolina.

Chang SY, Vizuete W, Serre M, Vennam LP, Omary M, Isakov V, Breen M, Arunachalam S.

Risk Anal. 2017 Dec;37(12):2420-2434. doi: 10.1111/risa.12775. Epub 2017 Feb 28.


Spectrum of disease associated with partial lipodystrophy: lessons from a trial cohort.

Ajluni N, Meral R, Neidert AH, Brady GF, Buras E, McKenna B, DiPaola F, Chenevert TL, Horowitz JF, Buggs-Saxton C, Rupani AR, Thomas PE, Tayeh MK, Innis JW, Omary MB, Conjeevaram H, Oral EA.

Clin Endocrinol (Oxf). 2017 May;86(5):698-707. doi: 10.1111/cen.13311. Epub 2017 Mar 27.


Not All Mice Are the Same: Standardization of Animal Research Data Presentation.

Omary MB, Cohen DE, El-Omar EM, Jalan R, Low MJ, Nathanson MH, Peek RM Jr, Turner JR.

Cell Mol Gastroenterol Hepatol. 2016 May 6;2(4):391-393. doi: 10.1016/j.jcmgh.2016.04.001. eCollection 2016 Jul. No abstract available.


Modeled Full-Flight Aircraft Emissions Impacts on Air Quality and Their Sensitivity to Grid Resolution.

Vennam LP, Vizuete W, Talgo K, Omary M, Binkowski FS, Xing J, Mathur R, Arunachalam S.

J Geophys Res Atmos. 2017;122(24):13472-13494. doi: 10.1002/2017JD026598.


Clusterin and Pycr1 alterations associate with strain and model differences in susceptibility to experimental pancreatitis.

Iyer S, Park MJ, Moons D, Kwan R, Liao J, Liu L, Omary MB.

Biochem Biophys Res Commun. 2017 Jan 22;482(4):1346-1352. doi: 10.1016/j.bbrc.2016.12.039. Epub 2016 Dec 7.


Mouse genetic background contributes to hepatocyte susceptibility to Fas-mediated apoptosis.

Weerasinghe SV, Park MJ, Portney DA, Omary MB.

Mol Biol Cell. 2016 Oct 15;27(20):3005-3012. Epub 2016 Aug 17.


Ethanol and Acetaminophen Synergistically Induce Hepatic Aggregation and TCH346-Insensitive Nuclear Translocation of GAPDH.

Snider NT, Portney DA, Willcockson HH, Maitra D, Martin HC, Greenson JK, Omary MB.

PLoS One. 2016 Aug 11;11(8):e0160982. doi: 10.1371/journal.pone.0160982. eCollection 2016.


Keratin impact on PKCδ- and ASMase-mediated regulation of hepatocyte lipid raft size - implication for FasR-associated apoptosis.

Gilbert S, Loranger A, Omary MB, Marceau N.

J Cell Sci. 2016 Sep 1;129(17):3262-73. doi: 10.1242/jcs.171124. Epub 2016 Jul 15.


Gastroenterology 2011-2016: Looking Back and Forward.

Omary MB, Carethers JM, Owyang C.

Gastroenterology. 2016 Jun;150(7):1496-1502. doi: 10.1053/j.gastro.2016.04.005. No abstract available.


E4BP4 is an insulin-induced stabilizer of nuclear SREBP-1c and promotes SREBP-1c-mediated lipogenesis.

Tong X, Li P, Zhang D, VanDommelen K, Gupta N, Rui L, Omary MB, Yin L.

J Lipid Res. 2016 Jul;57(7):1219-30. doi: 10.1194/jlr.M067181. Epub 2016 Jun 1.


Not all mice are the same: Standardization of animal research data presentation.

Omary MB, Cohen DE, El-Omar EM, Jalan R, Low MJ, Nathanson MH, Peek RM Jr, Turner JR.

Hepatology. 2016 Jun;63(6):1752-4. doi: 10.1002/hep.28608. No abstract available.


Not All Mice Are the Same: Standardization of Animal Research Data Presentation.

Omary MB, Cohen DE, El-Omar E, Jalan R, Low M, Nathanson M, Peek R, Turner J.

Gut. 2016 Jun;65(6):894-5. doi: 10.1136/gutjnl-2016-312041. No abstract available.


Not All Mice Are the Same: Standardization of Animal Research Data Presentation.

Omary MB, Cohen DE, El-Omar EM, Jalan R, Low MJ, Nathanson MH, Peek RM Jr, Turner JR.

Gastroenterology. 2016 Jun;150(7):1503-1504. doi: 10.1053/j.gastro.2016.03.034. Epub 2016 Apr 8. No abstract available.


Mentoring: A Necessary But Not Sufficient Ingredient for Enhancing Success.

Omary MB.

Gastroenterology. 2016 May;150(5):1067-1070. doi: 10.1053/j.gastro.2016.03.001. Epub 2016 Mar 3. Review. No abstract available.


Keratins: Biomarkers and modulators of apoptotic and necrotic cell death in the liver.

Ku NO, Strnad P, Bantel H, Omary MB.

Hepatology. 2016 Sep;64(3):966-76. doi: 10.1002/hep.28493. Epub 2016 Apr 4. Review.


A precursor-inducible zebrafish model of acute protoporphyria with hepatic protein aggregation and multiorganelle stress.

Elenbaas JS, Maitra D, Liu Y, Lentz SI, Nelson B, Hoenerhoff MJ, Shavit JA, Omary MB.

FASEB J. 2016 May;30(5):1798-810. doi: 10.1096/fj.201500111R. Epub 2016 Feb 2.



Omary MB, Liem RK.

Methods Enzymol. 2016;568:xxiii-xxiv. doi: 10.1016/S0076-6879(16)00052-5. No abstract available.


High-Throughput Screening for Drugs that Modulate Intermediate Filament Proteins.

Sun J, Groppi VE, Gui H, Chen L, Xie Q, Liu L, Omary MB.

Methods Enzymol. 2016;568:163-85. doi: 10.1016/bs.mie.2015.09.029. Epub 2015 Nov 19.


Assays for Posttranslational Modifications of Intermediate Filament Proteins.

Snider NT, Omary MB.

Methods Enzymol. 2016;568:113-38. doi: 10.1016/bs.mie.2015.09.005. Epub 2015 Nov 6.


Cell biology to disease and back.

Omary MB.

Nat Rev Mol Cell Biol. 2016 Jan;17(1):4. doi: 10.1038/nrm.2015.9. Epub 2015 Dec 2. No abstract available.


Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1.

Zhang H, Ramakrishnan SK, Triner D, Centofanti B, Maitra D, Győrffy B, Sebolt-Leopold JS, Dame MK, Varani J, Brenner DE, Fearon ER, Omary MB, Shah YM.

Sci Signal. 2015 Oct 6;8(397):ra98. doi: 10.1126/scisignal.aac5418.


Absence of keratin 8 or 18 promotes antimitochondrial autoantibody formation in aging male mice.

Toivola DM, Habtezion A, Misiorek JO, Zhang L, Nyström JH, Sharpe O, Robinson WH, Kwan R, Omary MB.

FASEB J. 2015 Dec;29(12):5081-9. doi: 10.1096/fj.14-269795. Epub 2015 Sep 23.


Prevalence of genetic variants of keratins 8 and 18 in patients with drug-induced liver injury.

Usachov V, Urban TJ, Fontana RJ, Gross A, Iyer S, Omary MB, Strnad P; Drug-Induced Liver Injury Network.

BMC Med. 2015 Aug 19;13:196. doi: 10.1186/s12916-015-0418-0.


Ambient Light Promotes Selective Subcellular Proteotoxicity after Endogenous and Exogenous Porphyrinogenic Stress.

Maitra D, Elenbaas JS, Whitesall SE, Basrur V, D'Alecy LG, Omary MB.

J Biol Chem. 2015 Sep 25;290(39):23711-24. doi: 10.1074/jbc.M114.636001. Epub 2015 Jul 23.


PKC412 normalizes mutation-related keratin filament disruption and hepatic injury in mice by promoting keratin-myosin binding.

Kwan R, Chen L, Looi K, Tao GZ, Weerasinghe SV, Snider NT, Conti MA, Adelstein RS, Xie Q, Omary MB.

Hepatology. 2015 Dec;62(6):1858-69. doi: 10.1002/hep.27965. Epub 2015 Aug 25.

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