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Items: 44

1.

Going through a phase.

Li Z, Morris SNS, Olzmann JA.

Nat Chem Biol. 2020 Feb;16(2):111-112. doi: 10.1038/s41589-019-0448-6. No abstract available.

PMID:
31932722
2.

The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis.

Bersuker K, Hendricks JM, Li Z, Magtanong L, Ford B, Tang PH, Roberts MA, Tong B, Maimone TJ, Zoncu R, Bassik MC, Nomura DK, Dixon SJ, Olzmann JA.

Nature. 2019 Nov;575(7784):688-692. doi: 10.1038/s41586-019-1705-2. Epub 2019 Oct 21.

PMID:
31634900
3.

Covalent targeting of the vacuolar H+-ATPase activates autophagy via mTORC1 inhibition.

Chung CY, Shin HR, Berdan CA, Ford B, Ward CC, Olzmann JA, Zoncu R, Nomura DK.

Nat Chem Biol. 2019 Aug;15(8):776-785. doi: 10.1038/s41589-019-0308-4. Epub 2019 Jul 8.

4.

A Tense Situation: Maintaining ER Homeostasis during Lipid Droplet Budding.

Morris SNS, Olzmann JA.

Dev Cell. 2019 Jul 1;50(1):1-2. doi: 10.1016/j.devcel.2019.06.005.

PMID:
31265808
5.

Harnessing the anti-cancer natural product nimbolide for targeted protein degradation.

Spradlin JN, Hu X, Ward CC, Brittain SM, Jones MD, Ou L, To M, Proudfoot A, Ornelas E, Woldegiorgis M, Olzmann JA, Bussiere DE, Thomas JR, Tallarico JA, McKenna JM, Schirle M, Maimone TJ, Nomura DK.

Nat Chem Biol. 2019 Jul;15(7):747-755. doi: 10.1038/s41589-019-0304-8. Epub 2019 Jun 17.

6.

Identification of Lipid Droplet Proteomes by Proximity Labeling Proteomics Using APEX2.

Bersuker K, Olzmann JA.

Methods Mol Biol. 2019;2008:57-72. doi: 10.1007/978-1-4939-9537-0_5.

7.

Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells.

Berdan CA, Ho R, Lehtola HS, To M, Hu X, Huffman TR, Petri Y, Altobelli CR, Demeulenaere SG, Olzmann JA, Maimone TJ, Nomura DK.

Cell Chem Biol. 2019 Jul 18;26(7):1027-1035.e22. doi: 10.1016/j.chembiol.2019.03.016. Epub 2019 May 9.

PMID:
31080076
8.

Getting a handle on lipid droplets: Insights into ER-lipid droplet tethering.

Nguyen TB, Olzmann JA.

J Cell Biol. 2019 Apr 1;218(4):1089-1091. doi: 10.1083/jcb.201902160. Epub 2019 Mar 18.

9.

Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell State.

Magtanong L, Ko PJ, To M, Cao JY, Forcina GC, Tarangelo A, Ward CC, Cho K, Patti GJ, Nomura DK, Olzmann JA, Dixon SJ.

Cell Chem Biol. 2019 Mar 21;26(3):420-432.e9. doi: 10.1016/j.chembiol.2018.11.016. Epub 2019 Jan 24.

PMID:
30686757
10.

Dynamics and functions of lipid droplets.

Olzmann JA, Carvalho P.

Nat Rev Mol Cell Biol. 2019 Mar;20(3):137-155. doi: 10.1038/s41580-018-0085-z. Review.

PMID:
30523332
11.

A Proteomic Map to Navigate Subcellular Reorganization in Fatty Liver Disease.

Li Z, Olzmann JA.

Dev Cell. 2018 Oct 22;47(2):139-141. doi: 10.1016/j.devcel.2018.10.006.

12.

In Close Proximity: The Lipid Droplet Proteome and Crosstalk With the Endoplasmic Reticulum.

Bersuker K, Olzmann JA.

Contact (Thousand Oaks). 2018 Jan-Dec;1. doi: 10.1177/2515256418768996. Epub 2018 Apr 3.

13.

A VCP inhibitor substrate trapping approach (VISTA) enables proteomic profiling of endogenous ERAD substrates.

Huang EY, To M, Tran E, Dionisio LTA, Cho HJ, Baney KLM, Pataki CI, Olzmann JA.

Mol Biol Cell. 2018 May 1;29(9):1021-1030. doi: 10.1091/mbc.E17-08-0514. Epub 2018 Mar 22.

14.

A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes.

Bersuker K, Peterson CWH, To M, Sahl SJ, Savikhin V, Grossman EA, Nomura DK, Olzmann JA.

Dev Cell. 2018 Jan 8;44(1):97-112.e7. doi: 10.1016/j.devcel.2017.11.020. Epub 2017 Dec 21.

15.

Chemoproteomics-Enabled Covalent Ligand Screening Reveals a Thioredoxin-Caspase 3 Interaction Disruptor That Impairs Breast Cancer Pathogenicity.

Anderson KE, To M, Olzmann JA, Nomura DK.

ACS Chem Biol. 2017 Oct 20;12(10):2522-2528. doi: 10.1021/acschembio.7b00711. Epub 2017 Sep 13.

16.

Lipid droplets and lipotoxicity during autophagy.

Nguyen TB, Olzmann JA.

Autophagy. 2017;13(11):2002-2003. doi: 10.1080/15548627.2017.1359451. Epub 2017 Sep 21.

17.

DGAT1-Dependent Lipid Droplet Biogenesis Protects Mitochondrial Function during Starvation-Induced Autophagy.

Nguyen TB, Louie SM, Daniele JR, Tran Q, Dillin A, Zoncu R, Nomura DK, Olzmann JA.

Dev Cell. 2017 Jul 10;42(1):9-21.e5. doi: 10.1016/j.devcel.2017.06.003.

18.

Establishing the lipid droplet proteome: Mechanisms of lipid droplet protein targeting and degradation.

Bersuker K, Olzmann JA.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Oct;1862(10 Pt B):1166-1177. doi: 10.1016/j.bbalip.2017.06.006. Epub 2017 Jun 13. Review.

19.

Characterization of protein complexes of the endoplasmic reticulum-associated degradation E3 ubiquitin ligase Hrd1.

Hwang J, Walczak CP, Shaler TA, Olzmann JA, Zhang L, Elias JE, Kopito RR.

J Biol Chem. 2017 Jun 2;292(22):9104-9116. doi: 10.1074/jbc.M117.785055. Epub 2017 Apr 14.

20.

Chemoproteomics-enabled covalent ligand screen reveals a cysteine hotspot in reticulon 4 that impairs ER morphology and cancer pathogenicity.

Bateman LA, Nguyen TB, Roberts AM, Miyamoto DK, Ku WM, Huffman TR, Petri Y, Heslin MJ, Contreras CM, Skibola CF, Olzmann JA, Nomura DK.

Chem Commun (Camb). 2017 Jun 29;53(53):7234-7237. doi: 10.1039/c7cc01480e.

21.

Lipid disequilibrium disrupts ER proteostasis by impairing ERAD substrate glycan trimming and dislocation.

To M, Peterson CW, Roberts MA, Counihan JL, Wu TT, Forster MS, Nomura DK, Olzmann JA.

Mol Biol Cell. 2017 Jan 15;28(2):270-284. doi: 10.1091/mbc.E16-07-0483. Epub 2016 Nov 23.

22.

Endoplasmic Reticulum-Associated Degradation and Lipid Homeostasis.

Stevenson J, Huang EY, Olzmann JA.

Annu Rev Nutr. 2016 Jul 17;36:511-42. doi: 10.1146/annurev-nutr-071715-051030. Epub 2016 May 26. Review.

23.

A polyubiquitin chain reaction: parkin recruitment to damaged mitochondria.

Riley BE, Olzmann JA.

PLoS Genet. 2015 Jan 22;11(1):e1004952. doi: 10.1371/journal.pgen.1004952. eCollection 2015 Jan. No abstract available.

24.

Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover.

Olzmann JA, Richter CM, Kopito RR.

Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1345-50. doi: 10.1073/pnas.1213738110. Epub 2013 Jan 7.

25.

The mammalian endoplasmic reticulum-associated degradation system.

Olzmann JA, Kopito RR, Christianson JC.

Cold Spring Harb Perspect Biol. 2013 Sep 1;5(9). pii: a013185. doi: 10.1101/cshperspect.a013185. Review.

26.

Unassembled CD147 is an endogenous endoplasmic reticulum-associated degradation substrate.

Tyler RE, Pearce MM, Shaler TA, Olzmann JA, Greenblatt EJ, Kopito RR.

Mol Biol Cell. 2012 Dec;23(24):4668-78. doi: 10.1091/mbc.E12-06-0428. Epub 2012 Oct 24.

27.

Making the cut: intramembrane cleavage by a rhomboid protease promotes ERAD.

Greenblatt EJ, Olzmann JA, Kopito RR.

Nat Struct Mol Biol. 2012 Oct;19(10):979-81. doi: 10.1038/nsmb.2398.

28.

Defining human ERAD networks through an integrative mapping strategy.

Christianson JC, Olzmann JA, Shaler TA, Sowa ME, Bennett EJ, Richter CM, Tyler RE, Greenblatt EJ, Harper JW, Kopito RR.

Nat Cell Biol. 2011 Nov 27;14(1):93-105. doi: 10.1038/ncb2383.

29.

Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant α-1 antitrypsin from the endoplasmic reticulum.

Greenblatt EJ, Olzmann JA, Kopito RR.

Nat Struct Mol Biol. 2011 Sep 11;18(10):1147-52. doi: 10.1038/nsmb.2111.

30.

Mutations associated with Charcot-Marie-Tooth disease cause SIMPLE protein mislocalization and degradation by the proteasome and aggresome-autophagy pathways.

Lee SM, Olzmann JA, Chin LS, Li L.

J Cell Sci. 2011 Oct 1;124(Pt 19):3319-31. doi: 10.1242/jcs.087114. Epub 2011 Sep 6.

31.

Lipid droplet formation is dispensable for endoplasmic reticulum-associated degradation.

Olzmann JA, Kopito RR.

J Biol Chem. 2011 Aug 12;286(32):27872-4. doi: 10.1074/jbc.C111.266452. Epub 2011 Jun 21.

32.

Parkin-mediated ubiquitin signalling in aggresome formation and autophagy.

Chin LS, Olzmann JA, Li L.

Biochem Soc Trans. 2010 Feb;38(Pt 1):144-9. doi: 10.1042/BST0380144. Review.

33.

SPFH1 and SPFH2 mediate the ubiquitination and degradation of inositol 1,4,5-trisphosphate receptors in muscarinic receptor-expressing HeLa cells.

Wang Y, Pearce MM, Sliter DA, Olzmann JA, Christianson JC, Kopito RR, Boeckmann S, Gagen C, Leichner GS, Roitelman J, Wojcikiewicz RJ.

Biochim Biophys Acta. 2009 Nov;1793(11):1710-8. doi: 10.1016/j.bbamcr.2009.09.004. Epub 2009 Sep 12.

34.

Corneal dystrophy-associated R124H mutation disrupts TGFBI interaction with Periostin and causes mislocalization to the lysosome.

Kim BY, Olzmann JA, Choi SI, Ahn SY, Kim TI, Cho HS, Suh H, Kim EK.

J Biol Chem. 2009 Jul 17;284(29):19580-91. doi: 10.1074/jbc.M109.013607. Epub 2009 May 28.

35.

Aggresome formation and neurodegenerative diseases: therapeutic implications.

Olzmann JA, Li L, Chin LS.

Curr Med Chem. 2008;15(1):47-60. Review.

36.
37.

Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6.

Olzmann JA, Li L, Chudaev MV, Chen J, Perez FA, Palmiter RD, Chin LS.

J Cell Biol. 2007 Sep 10;178(6):1025-38.

38.

PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1.

Pridgeon JW, Olzmann JA, Chin LS, Li L.

PLoS Biol. 2007 Jul;5(7):e172. Epub 2007 Jun 19.

39.

Spongiform neurodegeneration-associated E3 ligase Mahogunin ubiquitylates TSG101 and regulates endosomal trafficking.

Kim BY, Olzmann JA, Barsh GS, Chin LS, Li L.

Mol Biol Cell. 2007 Apr;18(4):1129-42. Epub 2007 Jan 17.

40.

Selective enrichment of DJ-1 protein in primate striatal neuronal processes: implications for Parkinson's disease.

Olzmann JA, Bordelon JR, Muly EC, Rees HD, Levey AI, Li L, Chin LS.

J Comp Neurol. 2007 Jan 20;500(3):585-99.

41.

Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases.

Choi J, Sullards MC, Olzmann JA, Rees HD, Weintraub ST, Bostwick DE, Gearing M, Levey AI, Chin LS, Li L.

J Biol Chem. 2006 Apr 21;281(16):10816-24. Epub 2006 Mar 3.

42.

Uncoupling proteins prevent glucose-induced neuronal oxidative stress and programmed cell death.

Vincent AM, Olzmann JA, Brownlee M, Sivitz WI, Russell JW.

Diabetes. 2004 Mar;53(3):726-34.

43.

Familial Parkinson's disease-associated L166P mutation disrupts DJ-1 protein folding and function.

Olzmann JA, Brown K, Wilkinson KD, Rees HD, Huai Q, Ke H, Levey AI, Li L, Chin LS.

J Biol Chem. 2004 Feb 27;279(9):8506-15. Epub 2003 Dec 9.

44.

High glucose-induced oxidative stress and mitochondrial dysfunction in neurons.

Russell JW, Golovoy D, Vincent AM, Mahendru P, Olzmann JA, Mentzer A, Feldman EL.

FASEB J. 2002 Nov;16(13):1738-48.

PMID:
12409316

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