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Items: 28

1.

Novel CHK1 inhibitor MU380 exhibits significant single-agent activity in TP53-mutated chronic lymphocytic leukemia cells.

Boudny M, Zemanova J, Khirsariya P, Borsky M, Verner J, Cerna J, Oltova A, Seda V, Mraz M, Jaros J, Jaskova Z, Spunarova M, Brychtova Y, Soucek K, Drapela S, Kasparkova M, Mayer J, Paruch K, Trbusek M.

Haematologica. 2019 Apr 11. pii: haematol.2018.203430. doi: 10.3324/haematol.2018.203430. [Epub ahead of print]

2.

Activation-induced deaminase and its splice variants associate with trisomy 12 in chronic lymphocytic leukemia.

Zaprazna K, Reblova K, Svobodova V, Radova L, Bystry V, Baloun J, Durechova K, Tom N, Loja T, Buresova M, Stranska K, Oltova A, Doubek M, Atchison ML, Trbusek M, Malcikova J, Pospisilova S.

Ann Hematol. 2019 Feb;98(2):423-435. doi: 10.1007/s00277-018-3520-5. Epub 2018 Oct 27.

PMID:
30368590
3.

Multiple productive IGH rearrangements denote oligoclonality even in immunophenotypically monoclonal CLL.

Brazdilova K, Plevova K, Skuhrova Francova H, Kockova H, Borsky M, Bikos V, Malcikova J, Oltova A, Kotaskova J, Tichy B, Brychtova Y, Mayer J, Doubek M, Pospisilova S.

Leukemia. 2018 Jan;32(1):234-236. doi: 10.1038/leu.2017.274. Epub 2017 Aug 29. No abstract available.

4.

Chromosome 6q deletion correlates with poor prognosis and low relative expression of FOXO3 in chronic lymphocytic leukemia patients.

Jarosova M, Hruba M, Oltova A, Plevova K, Kruzova L, Kriegova E, Fillerova R, Koritakova E, Doubek M, Lysak D, Prochazka V, Mraz M, Indrak K, Papajik T.

Am J Hematol. 2017 Oct;92(10):E604-E607. doi: 10.1002/ajh.24852. Epub 2017 Jul 29. No abstract available.

5.

Chk1 inhibition significantly potentiates activity of nucleoside analogs in TP53-mutated B-lymphoid cells.

Zemanova J, Hylse O, Collakova J, Vesely P, Oltova A, Borsky M, Zaprazna K, Kasparkova M, Janovska P, Verner J, Kohoutek J, Dzimkova M, Bryja V, Jaskova Z, Brychtova Y, Paruch K, Trbusek M.

Oncotarget. 2016 Sep 20;7(38):62091-62106. doi: 10.18632/oncotarget.11388.

6.

Ofatumumab added to dexamethasone in patients with relapsed or refractory chronic lymphocytic leukemia: Results from a phase II study.

Doubek M, Brychtova Y, Panovska A, Sebejova L, Stehlikova O, Chovancova J, Malcikova J, Smardova J, Plevova K, Volfova P, Trbusek M, Mraz M, Bakesova D, Trizuljak J, Hadrabova M, Obrtlikova P, Karban J, Smolej L, Oltova A, Jelinkova E, Pospisilova S, Mayer J.

Am J Hematol. 2015 May;90(5):417-21. doi: 10.1002/ajh.23964. Epub 2015 Apr 1.

7.

TP53 mutation analysis in chronic lymphocytic leukemia: comparison of different detection methods.

Kantorova B, Malcikova J, Smardova J, Pavlova S, Trbusek M, Tom N, Plevova K, Tichy B, Truong S, Diviskova E, Kotaskova J, Oltova A, Patten N, Brychtova Y, Doubek M, Mayer J, Pospisilova S.

Tumour Biol. 2015 May;36(5):3371-80. doi: 10.1007/s13277-014-2971-0. Epub 2014 Dec 20.

PMID:
25527155
8.

Frequent chromatin rearrangements in myelodysplastic syndromes--what stands behind?

Pagáčová E, Falk M, Falková I, Lukášová E, Michalová K, Oltová A, Raška I, Kozubek S.

Folia Biol (Praha). 2014;60 Suppl 1:1-7. Review.

PMID:
25369334
9.

Detailed analysis of therapy-driven clonal evolution of TP53 mutations in chronic lymphocytic leukemia.

Malcikova J, Stano-Kozubik K, Tichy B, Kantorova B, Pavlova S, Tom N, Radova L, Smardova J, Pardy F, Doubek M, Brychtova Y, Mraz M, Plevova K, Diviskova E, Oltova A, Mayer J, Pospisilova S, Trbusek M.

Leukemia. 2015 Apr;29(4):877-85. doi: 10.1038/leu.2014.297. Epub 2014 Oct 28.

10.

Clonal evolution in chronic lymphocytic leukemia detected by fluorescence in situ hybridization and conventional cytogenetics after stimulation with CpG oligonucleotides and interleukin-2: a prospective analysis.

Brejcha M, Stoklasová M, Brychtová Y, Panovská A, Štěpanovská K, Vaňková G, Plevová K, Oltová A, Horká K, Pospíšilová Š, Mayer J, Doubek M.

Leuk Res. 2014 Feb;38(2):170-5. doi: 10.1016/j.leukres.2013.10.019. Epub 2013 Oct 29.

PMID:
24246692
11.

[Chromosome banding analysis of peripheral blood lymphocytes stimulated with IL2 and CpG oligonucleotide DSP30 in patients with chronic lymphocytic leukemia].

Stěpanovská K, Vaňková G, Némethová V, Tomášiková L, Smuhařová P, Divíšková E, Vallová V, Kuglík P, Plevová K, Oltová A, Doubek M, Pospíšilová S, Mayer J.

Klin Onkol. 2013;26(4):263-70. Czech.

PMID:
23961857
12.

The BCR-ABL1 T315I mutation and additional genomic aberrations are dominant genetic lesions associated with disease progression in patients with chronic myelogenous leukemia resistant to tyrosine kinase inhibitor therapy.

Malcikova J, Razga F, Jurcek T, Dvorakova D, Zackova D, Toskova M, Sebejova L, Smardova J, Oltova A, Vankova G, Jurackova L, Trbusek M, Pospisilova S, Mayer J, Racil Z.

Leuk Lymphoma. 2013 Sep;54(9):2083-7. doi: 10.3109/10428194.2012.762649. Epub 2013 Feb 1. No abstract available.

PMID:
23289360
13.

Complex karyotype and translocation t(4;14) define patients with high-risk newly diagnosed multiple myeloma: results of CMG2002 trial.

Nemec P, Zemanova Z, Kuglik P, Michalova K, Tajtlova J, Kaisarova P, Oltova A, Filkova H, Holzerova M, Balcarkova J, Jarosova M, Rabasova J, Hruba M, Spicka I, Gregora E, Adam Z, Scudla V, Maisnar V, Schutzova M, Hajek R; Czech Myeloma Group.

Leuk Lymphoma. 2012 May;53(5):920-7. doi: 10.3109/10428194.2011.634042. Epub 2011 Dec 13.

PMID:
22023516
14.

Imatinib as the first-line treatment of patients with chronic myeloid leukemia diagnosed in the chronic phase: can we compare real life data to the results from clinical trials?

Zackova D, Klamova H, Dusek L, Muzik J, Polakova KM, Moravcova J, Jurcek T, Dvorakova D, Racil Z, Pospisil Z, Oltova A, Michalova K, Brezinova J, Razga F, Doubek M, Cetkovsky P, Trneny M, Mayer J.

Am J Hematol. 2011 Mar;86(3):318-21. doi: 10.1002/ajh.21942. Epub 2011 Feb 15. No abstract available.

15.

Dasatinib in imatinib-resistant or -intolerant CML patients: data from the clinical practice of 6 hematological centers in the Czech Republic.

Klamova H, Faber E, Zackova D, Markova M, Voglova J, Cmunt E, Novakova L, Machova-Polakova K, Moravcova J, Dvorakova D, Michalova K, Brezinova J, Oltova A, Jarosova M, Cetkovsky P, Indrak K, Mayer J.

Neoplasma. 2010;57(4):355-9.

PMID:
20429627
16.

Failure of molecular diagnostics in chronic myeloid leukemia: an aberrant form of e13a2 BCR-ABL transcript causing false-negative results by standard polymerase chain reaction.

Jurcek T, Razga F, Jeziskova I, Dvorakova D, Zackova D, Tomasikova L, Oltova A, Mayer J.

Leuk Lymphoma. 2010 Mar;51(3):558-61. doi: 10.3109/10428190903572219. No abstract available.

PMID:
20148758
17.

Prognosis of children with mixed phenotype acute leukemia treated on the basis of consistent immunophenotypic criteria.

Mejstrikova E, Volejnikova J, Fronkova E, Zdrahalova K, Kalina T, Sterba J, Jabali Y, Mihal V, Blazek B, Cerna Z, Prochazkova D, Hak J, Zemanova Z, Jarosova M, Oltova A, Sedlacek P, Schwarz J, Zuna J, Trka J, Stary J, Hrusak O.

Haematologica. 2010 Jun;95(6):928-35. doi: 10.3324/haematol.2009.014506. Epub 2010 Feb 9.

18.

Negative prognostic significance of two or more cytogenetic abnormalities in multiple myeloma patients treated with autologous stem cell transplantation.

Greslikova H, Zaoralova R, Filkova H, Nemec P, Oltova A, Kupska R, Rudolecka P, Smetana J, Pour L, Zahradova L, Krejci M, Buchler T, Adam Z, Hajek R, Kuglik P.

Neoplasma. 2010;57(2):111-7.

PMID:
20099973
19.

[Radiotherapy induced glioblastoma in a child previously treated for cerebellar medulloblastoma (case report and review of the literature)].

Pavelka Z, Brichtová E, Kren L, Skotáková J, Oltová A, Slampa P, Zitterbart K, Stĕrba J.

Klin Onkol. 2008;21(1):31-4. Czech.

PMID:
19097413
20.

Characterization of a GM7 glioblastoma cell line showing CD133 positivity and both cytoplasmic and nuclear localization of nestin.

Loja T, Chlapek P, Kuglik P, Pesakova M, Oltova A, Cejpek P, Veselska R.

Oncol Rep. 2009 Jan;21(1):119-27.

PMID:
19082452
21.

Efficacy of high-resolution comparative genomic hybridization (HR-CGH) in detection of chromosomal abnormalities in children with acute leukaemia.

Vranova V, Mentzlova D, Oltova A, Linkova V, Zezulkova D, Filkova H, Mendelova D, Sterba J, Kuglik P.

Neoplasma. 2008;55(1):23-30.

PMID:
18190236
22.

[The significance and current diagnostic options of cytogenetic changes in multiple myeloma].

Kuglík P, Filková H, Oltová A, Hájek R.

Vnitr Lek. 2006 Nov;52 Suppl 2:76-8. Review. Czech.

PMID:
18175433
23.

The optimization of sample treatment for spectral karyotyping with applications for human tumour cells.

Loja T, Kuglik P, Oltova A, Smuharova P, Zitterbart K, Bajciova V, Veselska R.

Cytogenet Genome Res. 2007;116(3):186-93.

PMID:
17317958
24.

[Comparison of standard prognostic factors with the deletion of 13q14 detected by interphase fluorescence in situ hybridization on separated and unseparated bone marrow cells in multiple myeloma].

Smejkalová J, Vranová V, Oltová A, Kuglík P, Filková H, Heinigová J, Kovárová L, Adam Z, Krejcí M, Pour L, Büchler T, Svobodník A, Vostrejsová S, Kalábová V, Vorlícek J, Penka M, Hájek R.

Cas Lek Cesk. 2005;144(7):483-8. Czech.

PMID:
16161543
25.

Treatment of chronic myeloid leukemia with autologous transplantation using peripheral blood stem cells or bone marrow cultured in IL-2 followed by IL-2, GM-CSF, and IFN-alpha administration.

Hájek R, Zácková D, Büchler T, Penka M, Krahulcová E, Korístek Z, Vinklárková J, Adler J, Janovská E, Indrák K, Faber E, Doubek M, Klabusay M, Oltová A, Kuglík P, Bourková L, Dusek L, Mareschová I, Mayer J, Vorlícek J.

Med Oncol. 2003;20(1):69-76.

PMID:
12665687
26.

Location of the BCR/ABL fusion genes on both chromosomes 9q34 in Ph negative chronic myeloid leukemia.

Michalová K, Zemanová Z, Bkezinová J, Moravcová J, Oltová A, Sobotka J, Kuglík P, Kozak T, Sindelarová L, Jankovská M, Obomilová A, Sieglová Z, Polák J, Nádvorníková S, Haskovec C.

Leuk Lymphoma. 2002 Aug;43(8):1695-700.

PMID:
12400616
27.

[Experience with prenatal genetic diagnosis of congenital developmental defects in the fetus].

Matýsek P, Uhlír M, Cuprová M, Vlasín P, Vebera Z, Oltová A, Frána L.

Cesk Gynekol. 1991 Nov;56(5-6):326-30. Czech. No abstract available.

PMID:
1815836
28.

Ultraviolet-sensitive and resistant mutants produced in HeLa S3 cells and their repair mechanisms.

Klímek M, Sevcíková P, Vlasínová M, Oltová A.

An Acad Bras Cienc. 1973;45 SUPPL:147-50. No abstract available.

PMID:
4806332

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