Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 585

1.

The impact of different human IgG capture molecules on the kinetic analysis of antibody-antigen interaction.

Kamat V, Rafique A, Huang T, Olsen O, Olson W.

Anal Biochem. 2020 Jan 9:113580. doi: 10.1016/j.ab.2020.113580. [Epub ahead of print]

2.

A class of costimulatory CD28-bispecific antibodies that enhance the antitumor activity of CD3-bispecific antibodies.

Skokos D, Waite JC, Haber L, Crawford A, Hermann A, Ullman E, Slim R, Godin S, Ajithdoss D, Ye X, Wang B, Wu Q, Ramos I, Pawashe A, Canova L, Vazzana K, Ram P, Herlihy E, Ahmed H, Oswald E, Golubov J, Poon P, Havel L, Chiu D, Lazo M, Provoncha K, Yu K, Kim J, Warsaw JJ, Stokes Oristian N, Siao CJ, Dudgeon D, Huang T, Potocky T, Martin J, MacDonald D, Oyejide A, Rafique A, Poueymirou W, Kirshner JR, Smith E, Olson W, Lin J, Thurston G, Sleeman MA, Murphy AJ, Yancopoulos GD.

Sci Transl Med. 2020 Jan 8;12(525). pii: eaaw7888. doi: 10.1126/scitranslmed.aaw7888.

PMID:
31915305
3.

[Opposite Effects of Histone H1 and HMGN5 Protein on Distant Interactions in Chromatin].

Nizovtseva EV, Polikanov YS, Kulaeva OI, Clauvelin N, Postnikov YV, Olson WK, Studitsky VM.

Mol Biol (Mosk). 2019 Nov-Dec;53(6):1038-1048. doi: 10.1134/S0026898419060132. Russian.

4.

A biparatopic antibody that modulates MET trafficking exhibits enhanced efficacy compared to parental antibodies in MET-driven tumor models.

DaSilva JO, Yang K, Perez Bay AE, Andreev J, Ngoi P, Pyles E, Franklin MC, Dudgeon D, Rafique A, Dore A, Delfino FJ, Potocky T, Babb R, Chen G, MacDonald D, Olson WC, Thurston G, Daly C.

Clin Cancer Res. 2019 Dec 17. pii: clincanres.2428.2019. doi: 10.1158/1078-0432.CCR-19-2428. [Epub ahead of print]

PMID:
31848185
5.

PSMA ADC monotherapy in patients with progressive metastatic castration-resistant prostate cancer following abiraterone and/or enzalutamide: Efficacy and safety in open-label single-arm phase 2 study.

Petrylak DP, Vogelzang NJ, Chatta K, Fleming MT, Smith DC, Appleman LJ, Hussain A, Modiano M, Singh P, Tagawa ST, Gore I, McClay EF, Mega AE, Sartor AO, Somer B, Wadlow R, Shore ND, Olson WC, Stambler N, DiPippo VA, Israel RJ.

Prostate. 2020 Jan;80(1):99-108. doi: 10.1002/pros.23922. Epub 2019 Nov 19.

PMID:
31742767
6.

Orphan Nuclear Receptor NR2F6 Suppresses T Follicular Helper Cell Accumulation through Regulation of IL-21.

Olson WJ, Jakic B, Labi V, Schoeler K, Kind M, Klepsch V, Baier G, Hermann-Kleiter N.

Cell Rep. 2019 Sep 10;28(11):2878-2891.e5. doi: 10.1016/j.celrep.2019.08.024.

7.

A novel bispecific antibody platform to direct complement activity for efficient lysis of target cells.

Cruz JW, Damko E, Modi B, Tu N, Meagher K, Voronina V, Gartner H, Ehrlich G, Rafique A, Babb R, Aneja P, Potocky TB, D' Orvilliers A, Coppi A, E SY, Qiu H, Williams CM, Bennett BL, Chen G, Macdonald L, Olson W, Lin JC, Stahl N, Murphy AJ, Kyratsous CA, Prasad BC.

Sci Rep. 2019 Aug 19;9(1):12031. doi: 10.1038/s41598-019-48461-1.

8.

Preclinical Development of the Anti-LAG-3 Antibody REGN3767: Characterization and Activity in Combination with the Anti-PD-1 Antibody Cemiplimab in Human PD-1xLAG-3-Knockin Mice.

Burova E, Hermann A, Dai J, Ullman E, Halasz G, Potocky T, Hong S, Liu M, Allbritton O, Woodruff A, Pei J, Rafique A, Poueymirou W, Martin J, MacDonald D, Olson WC, Murphy A, Ioffe E, Thurston G, Mohrs M.

Mol Cancer Ther. 2019 Nov;18(11):2051-2062. doi: 10.1158/1535-7163.MCT-18-1376. Epub 2019 Aug 8.

PMID:
31395688
9.

A Mucin 16 bispecific T cell-engaging antibody for the treatment of ovarian cancer.

Crawford A, Haber L, Kelly MP, Vazzana K, Canova L, Ram P, Pawashe A, Finney J, Jalal S, Chiu D, Colleton CA, Garnova E, Makonnen S, Hickey C, Krueger P, DelFino F, Potocky T, Kuhnert J, Godin S, Retter MW, Duramad P, MacDonald D, Olson WC, Fairhurst J, Huang T, Martin J, Lin JC, Smith E, Thurston G, Kirshner JR.

Sci Transl Med. 2019 Jun 19;11(497). pii: eaau7534. doi: 10.1126/scitranslmed.aau7534.

PMID:
31217340
10.

Alternatively activated macrophage-derived secretome stimulates ovarian cancer spheroid spreading through a JAK2/STAT3 pathway.

Fogg KC, Olson WR, Miller JN, Khan A, Renner C, Hale I, Weisman PS, Kreeger PK.

Cancer Lett. 2019 Aug 28;458:92-101. doi: 10.1016/j.canlet.2019.05.029. Epub 2019 May 24.

PMID:
31129149
11.

Computational Simulation of Adapter Length-Dependent LASSO Probe Capture Efficiency.

Liu J, Shukor S, Li S, Tamayo A, Tosi L, Larman B, Nanda V, Olson WK, Parekkadan B.

Biomolecules. 2019 May 22;9(5). pii: E199. doi: 10.3390/biom9050199.

12.

Web 3DNA 2.0 for the analysis, visualization, and modeling of 3D nucleic acid structures.

Li S, Olson WK, Lu XJ.

Nucleic Acids Res. 2019 Jul 2;47(W1):W26-W34. doi: 10.1093/nar/gkz394.

13.

Effects of Noncanonical Base Pairing on RNA Folding: Structural Context and Spatial Arrangements of G·A Pairs.

Olson WK, Li S, Kaukonen T, Colasanti AV, Xin Y, Lu XJ.

Biochemistry. 2019 May 21;58(20):2474-2487. doi: 10.1021/acs.biochem.9b00122. Epub 2019 May 8.

PMID:
31008589
14.

Leaky expression of channelrhodopsin-2 (ChR2) in Ai32 mouse lines.

Prabhakar A, Vujovic D, Cui L, Olson W, Luo W.

PLoS One. 2019 Mar 26;14(3):e0213326. doi: 10.1371/journal.pone.0213326. eCollection 2019.

15.

Directed Differentiation of Human Pluripotent Stem Cells to Podocytes under Defined Conditions.

Qian T, Hernday SE, Bao X, Olson WR, Panzer SE, Shusta EV, Palecek SP.

Sci Rep. 2019 Feb 26;9(1):2765. doi: 10.1038/s41598-019-39504-8.

16.

Phase 1 study of PSMA ADC, an antibody-drug conjugate targeting prostate-specific membrane antigen, in chemotherapy-refractory prostate cancer.

Petrylak DP, Kantoff P, Vogelzang NJ, Mega A, Fleming MT, Stephenson JJ Jr, Frank R, Shore ND, Dreicer R, McClay EF, Berry WR, Agarwal M, DiPippo VA, Rotshteyn Y, Stambler N, Olson WC, Morris SA, Israel RJ.

Prostate. 2019 May;79(6):604-613. doi: 10.1002/pros.23765. Epub 2019 Jan 20.

PMID:
30663074
17.

Formation and phenotypic characterization of CD49a, CD49b and CD103 expressing CD8 T cell populations in human metastatic melanoma.

Melssen MM, Olson W, Wages NA, Capaldo BJ, Mauldin IS, Mahmutovic A, Hutchison C, Melief CJM, Bullock TN, Engelhard VH, Slingluff CL Jr.

Oncoimmunology. 2018 Aug 6;7(10):e1490855. doi: 10.1080/2162402X.2018.1490855. eCollection 2018.

18.

Multiplex Immuno-Liquid Chromatography-Mass Spectrometry-Parallel Reaction Monitoring (LC-MS-PRM) Quantitation of CD8A, CD4, LAG3, PD1, PD-L1, and PD-L2 in Frozen Human Tissues.

Zhang Q, Salzler R, Dore A, Yang J, Ma D, Olson WC, Liu Y.

J Proteome Res. 2018 Nov 2;17(11):3932-3940. doi: 10.1021/acs.jproteome.8b00605. Epub 2018 Oct 11.

PMID:
30277784
19.

Somatotopic organization of central arbors from nociceptive afferents develops independently of their intact peripheral target innervation.

Olson W, Luo W.

J Comp Neurol. 2018 Dec 15;526(18):3058-3065. doi: 10.1002/cne.24533. Epub 2018 Oct 30.

20.

Toward a Universal Structural and Energetic Model for Prokaryotic Promoters.

Mishra A, Siwach P, Misra P, Jayaram B, Bansal M, Olson WK, Thayer KM, Beveridge DL.

Biophys J. 2018 Oct 2;115(7):1180-1189. doi: 10.1016/j.bpj.2018.08.002. Epub 2018 Aug 8.

21.

Epitope Mapping by HDX-MS Elucidates the Surface Coverage of Antigens Associated with High Blocking Efficiency of Antibodies to Birch Pollen Allergen.

Zhang Q, Yang J, Bautista J, Badithe A, Olson W, Liu Y.

Anal Chem. 2018 Oct 2;90(19):11315-11323. doi: 10.1021/acs.analchem.8b01864. Epub 2018 Sep 14.

PMID:
30170487
22.

Development of Clinical-Stage Human Monoclonal Antibodies That Treat Advanced Ebola Virus Disease in Nonhuman Primates.

Pascal KE, Dudgeon D, Trefry JC, Anantpadma M, Sakurai Y, Murin CD, Turner HL, Fairhurst J, Torres M, Rafique A, Yan Y, Badithe A, Yu K, Potocky T, Bixler SL, Chance TB, Pratt WD, Rossi FD, Shamblin JD, Wollen SE, Zelko JM, Carrion R Jr, Worwa G, Staples HM, Burakov D, Babb R, Chen G, Martin J, Huang TT, Erlandson K, Willis MS, Armstrong K, Dreier TM, Ward AB, Davey RA, Pitt MLM, Lipsich L, Mason P, Olson W, Stahl N, Kyratsous CA.

J Infect Dis. 2018 Nov 22;218(suppl_5):S612-S626. doi: 10.1093/infdis/jiy285.

23.

ImmunoPET Imaging of Endogenous and Transfected Prolactin Receptor Tumor Xenografts.

Cheal SM, Ruan S, Veach DR, Longo VA, Punzalan BJ, Wu J, Fung EK, Kelly MP, Kirshner JR, Giurleo JT, Ehrlich G, Han AQ, Thurston G, Olson WC, Zanzonico PB, Larson SM, Carrasquillo JA.

Mol Pharm. 2018 Jun 4;15(6):2133-2141. doi: 10.1021/acs.molpharmaceut.7b01133. Epub 2018 Apr 30.

24.

Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement.

Orengo JM, Radin AR, Kamat V, Badithe A, Ben LH, Bennett BL, Zhong S, Birchard D, Limnander A, Rafique A, Bautista J, Kostic A, Newell D, Duan X, Franklin MC, Olson W, Huang T, Gandhi NA, Lipsich L, Stahl N, Papadopoulos NJ, Murphy AJ, Yancopoulos GD.

Nat Commun. 2018 Apr 12;9(1):1421. doi: 10.1038/s41467-018-03636-8.

25.

A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease.

Abul-Husn NS, Cheng X, Li AH, Xin Y, Schurmann C, Stevis P, Liu Y, Kozlitina J, Stender S, Wood GC, Stepanchick AN, Still MD, McCarthy S, O'Dushlaine C, Packer JS, Balasubramanian S, Gosalia N, Esopi D, Kim SY, Mukherjee S, Lopez AE, Fuller ED, Penn J, Chu X, Luo JZ, Mirshahi UL, Carey DJ, Still CD, Feldman MD, Small A, Damrauer SM, Rader DJ, Zambrowicz B, Olson W, Murphy AJ, Borecki IB, Shuldiner AR, Reid JG, Overton JD, Yancopoulos GD, Hobbs HH, Cohen JC, Gottesman O, Teslovich TM, Baras A, Mirshahi T, Gromada J, Dewey FE.

N Engl J Med. 2018 Mar 22;378(12):1096-1106. doi: 10.1056/NEJMoa1712191.

26.

Evaluation of SAS1B as a target for antibody-drug conjugate therapy in the treatment of pancreatic cancer.

Knapp KA, Pires ES, Adair SJ, Mandal A, Mills AM, Olson WC, Slingluff CL Jr, Parsons JT, Bauer TW, Bullock TN, Herr JC.

Oncotarget. 2018 Jan 4;9(10):8972-8984. doi: 10.18632/oncotarget.23944. eCollection 2018 Feb 6.

27.

A pilot study of the immunogenicity of a 9-peptide breast cancer vaccine plus poly-ICLC in early stage breast cancer.

Dillon PM, Petroni GR, Smolkin ME, Brenin DR, Chianese-Bullock KA, Smith KT, Olson WC, Fanous IS, Nail CJ, Brenin CM, Hall EH, Slingluff CL Jr.

J Immunother Cancer. 2017 Nov 21;5(1):92. doi: 10.1186/s40425-017-0295-5.

28.

Directed differentiation of human pluripotent stem cells to blood-brain barrier endothelial cells.

Qian T, Maguire SE, Canfield SG, Bao X, Olson WR, Shusta EV, Palecek SP.

Sci Adv. 2017 Nov 8;3(11):e1701679. doi: 10.1126/sciadv.1701679. eCollection 2017 Nov.

29.

Parallels between DNA and collagen - comparing elastic models of the double and triple helix.

Xu F, Zheng H, Clauvelin N, Lu XJ, Olson WK, Nanda V.

Sci Rep. 2017 Oct 16;7(1):12802. doi: 10.1038/s41598-017-12878-3.

30.

Sparse genetic tracing reveals regionally specific functional organization of mammalian nociceptors.

Olson W, Abdus-Saboor I, Cui L, Burdge J, Raabe T, Ma M, Luo W.

Elife. 2017 Oct 12;6. pii: e29507. doi: 10.7554/eLife.29507.

31.

Opportunities for therapeutic antibodies directed at G-protein-coupled receptors.

Hutchings CJ, Koglin M, Olson WC, Marshall FH.

Nat Rev Drug Discov. 2017 Sep 1;16(9):661. doi: 10.1038/nrd.2017.173. No abstract available.

PMID:
28860586
32.

Vaccine-draining lymph nodes of cancer patients for generating anti-cancer antibodies.

Shukla GS, Olson WC, Pero SC, Sun YJ, Carman CL, Slingluff CL Jr, Krag DN.

J Transl Med. 2017 Aug 29;15(1):180. doi: 10.1186/s12967-017-1283-8.

33.

The Stem Cell Marker Lgr5 Defines a Subset of Postmitotic Neurons in the Olfactory Bulb.

Yu Y, Moberly AH, Bhattarai JP, Duan C, Zheng Q, Li F, Huang H, Olson W, Luo W, Wen T, Yu H, Ma M.

J Neurosci. 2017 Sep 27;37(39):9403-9414. doi: 10.1523/JNEUROSCI.0500-17.2017. Epub 2017 Aug 28.

34.

Towards quantitative analysis of gene regulation by enhancers.

Nizovtseva EV, Todolli S, Olson WK, Studitsky VM.

Epigenomics. 2017 Sep;9(9):1219-1231. doi: 10.2217/epi-2017-0061. Epub 2017 Aug 11. Review.

35.

Nuclear orphan receptor NR2F6 as a safeguard against experimental murine colitis.

Klepsch V, Gerner RR, Klepsch S, Olson WJ, Tilg H, Moschen AR, Baier G, Hermann-Kleiter N.

Gut. 2018 Aug;67(8):1434-1444. doi: 10.1136/gutjnl-2016-313466. Epub 2017 Aug 4.

36.

THE GLOBAL PRECIPITATION MEASUREMENT (GPM) MISSION FOR SCIENCE AND SOCIETY.

Skofronick-Jackson G, Petersen WA, Berg W, Kidd C, Stocker EF, Kirschbaum DB, Kakar R, Braun SA, Huffman GJ, Iguchi T, Kirstetter PE, Kummerow C, Meneghini R, Oki R, Olson WS, Takayabu YN, Furukawa K, Wilheit T.

Bull Am Meteorol Soc. 2017 Aug;98(8):1679-1695. doi: 10.1175/BAMS-D-15-00306.1. Epub 2017 Sep 6.

37.

Opportunities for therapeutic antibodies directed at G-protein-coupled receptors.

Hutchings CJ, Koglin M, Olson WC, Marshall FH.

Nat Rev Drug Discov. 2017 Sep;16(9):787-810. doi: 10.1038/nrd.2017.91. Epub 2017 Jul 14. Review. Erratum in: Nat Rev Drug Discov. 2017 Sep 1;16(9):661.

PMID:
28706220
38.

The emerging role of DNA supercoiling as a dynamic player in genomic structure and function.

Finzi L, Olson WK.

Biophys Rev. 2016 Nov;8(Suppl 1):1-3. doi: 10.1007/s12551-016-0214-x. Epub 2016 Jul 7. Review.

39.

Insights into genome architecture deduced from the properties of short Lac repressor-mediated DNA loops.

Perez PJ, Olson WK.

Biophys Rev. 2016 Nov;8(Suppl 1):135-144. doi: 10.1007/s12551-016-0209-7. Epub 2016 Jul 2. Review.

40.

Factors associated with success of telaprevir- and boceprevir-based triple therapy for hepatitis C virus infection.

Bichoupan K, Tandon N, Martel-Laferriere V, Patel NM, Sachs D, Ng M, Schonfeld EA, Pappas A, Crismale J, Stivala A, Khaitova V, Gardenier D, Linderman M, Olson W, Perumalswami PV, Schiano TD, Odin JA, Liu LU, Dieterich DT, Branch AD.

World J Hepatol. 2017 Apr 18;9(11):551-561. doi: 10.4254/wjh.v9.i11.551.

41.

Patient Preference for Dosing Frequency Based on Prior Biologic Experience.

Zhang M, Carter C, Olson WH, Johnson MP, Brennem SK, Lee S, Farahi K.

J Drugs Dermatol. 2017 Mar 1;16(3):220-226.

PMID:
28301617
42.

Characterization of the Anti-PD-1 Antibody REGN2810 and Its Antitumor Activity in Human PD-1 Knock-In Mice.

Burova E, Hermann A, Waite J, Potocky T, Lai V, Hong S, Liu M, Allbritton O, Woodruff A, Wu Q, D'Orvilliers A, Garnova E, Rafique A, Poueymirou W, Martin J, Huang T, Skokos D, Kantrowitz J, Popke J, Mohrs M, MacDonald D, Ioffe E, Olson W, Lowy I, Murphy A, Thurston G.

Mol Cancer Ther. 2017 May;16(5):861-870. doi: 10.1158/1535-7163.MCT-16-0665. Epub 2017 Mar 6.

43.

Insights into Genome Architecture Deduced from the Properties of Short Lac Repressor-mediated DNA Loops.

Perez PJ, Olson WK.

Biophys Rev. 2016 Nov;8(1 Suppl):135-144. doi: 10.1007/s12551-016-0209-7. Epub 2016 Jul 2.

44.

Bispecific Antibodies and Antibody-Drug Conjugates (ADCs) Bridging HER2 and Prolactin Receptor Improve Efficacy of HER2 ADCs.

Andreev J, Thambi N, Perez Bay AE, Delfino F, Martin J, Kelly MP, Kirshner JR, Rafique A, Kunz A, Nittoli T, MacDonald D, Daly C, Olson W, Thurston G.

Mol Cancer Ther. 2017 Apr;16(4):681-693. doi: 10.1158/1535-7163.MCT-16-0658. Epub 2017 Jan 20.

45.

Contributions of Sequence to the Higher-Order Structures of DNA.

Todolli S, Perez PJ, Clauvelin N, Olson WK.

Biophys J. 2017 Feb 7;112(3):416-426. doi: 10.1016/j.bpj.2016.11.017. Epub 2016 Dec 9. Review.

46.

Nucleosome-free DNA regions differentially affect distant communication in chromatin.

Nizovtseva EV, Clauvelin N, Todolli S, Polikanov YS, Kulaeva OI, Wengrzynek S, Olson WK, Studitsky VM.

Nucleic Acids Res. 2017 Apr 7;45(6):3059-3067. doi: 10.1093/nar/gkw1240.

47.

Identification of Early RET+ Deep Dorsal Spinal Cord Interneurons in Gating Pain.

Cui L, Miao X, Liang L, Abdus-Saboor I, Olson W, Fleming MS, Ma M, Tao YX, Luo W.

Neuron. 2016 Sep 21;91(6):1413. doi: 10.1016/j.neuron.2016.09.010. Epub 2016 Sep 21. No abstract available.

48.

Identification of Early RET+ Deep Dorsal Spinal Cord Interneurons in Gating Pain.

Cui L, Miao X, Liang L, Abdus-Saboor I, Olson W, Fleming MS, Ma M, Tao YX, Luo W.

Neuron. 2016 Sep 7;91(5):1137-1153. doi: 10.1016/j.neuron.2016.07.038. Epub 2016 Aug 18. Erratum in: Neuron. 2016 Sep 21;91(6):1413.

49.

Topical treatment of melanoma metastases with imiquimod, plus administration of a cancer vaccine, promotes immune signatures in the metastases.

Mauldin IS, Wages NA, Stowman AM, Wang E, Olson WC, Deacon DH, Smith KT, Galeassi N, Teague JE, Smolkin ME, Chianese-Bullock KA, Clark RA, Petroni GR, Marincola FM, Mullins DW, Slingluff CL Jr.

Cancer Immunol Immunother. 2016 Oct;65(10):1201-12. doi: 10.1007/s00262-016-1880-z. Epub 2016 Aug 13.

50.

Intratumoral interferon-gamma increases chemokine production but fails to increase T cell infiltration of human melanoma metastases.

Mauldin IS, Wages NA, Stowman AM, Wang E, Smolkin ME, Olson WC, Deacon DH, Smith KT, Galeassi NV, Chianese-Bullock KA, Dengel LT, Marincola FM, Petroni GR, Mullins DW, Slingluff CL Jr.

Cancer Immunol Immunother. 2016 Oct;65(10):1189-99. doi: 10.1007/s00262-016-1881-y. Epub 2016 Aug 13.

Supplemental Content

Support Center