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Correction to: Mechanisms underlying the EEG biomarker in Dup15q syndrome.

Frohlich J, Reiter LT, Saravanapandian V, DiStefano C, Huberty S, Hyde C, Chamberlain S, Bearden CE, Golshani P, Irimia A, Olsen RW, Hipp JF, Jeste SS.

Mol Autism. 2019 Nov 6;10:37. doi: 10.1186/s13229-019-0288-y. eCollection 2019.


Cryo-electron microscopy reveals informative details of GABAA receptor structural pharmacology: implications for drug discovery.

Olsen RW, Lindemeyer AK, Wallner M, Li X, Huynh KW, Zhou ZH.

Ann Transl Med. 2019 Jul;7(Suppl 3):S144. doi: 10.21037/atm.2019.06.23. No abstract available.


Mechanisms underlying the EEG biomarker in Dup15q syndrome.

Frohlich J, Reiter LT, Saravanapandian V, DiStefano C, Huberty S, Hyde C, Chamberlain S, Bearden CE, Golshani P, Irimia A, Olsen RW, Hipp JF, Jeste SS.

Mol Autism. 2019 Jul 3;10:29. doi: 10.1186/s13229-019-0280-6. eCollection 2019. Erratum in: Mol Autism. 2019 Nov 6;10:37.


Acquisition of IgG to ICAM-1-Binding DBLβ Domains in the Plasmodium falciparum Erythrocyte Membrane Protein 1 Antigen Family Varies between Groups A, B, and C.

Olsen RW, Ecklu-Mensah G, Bengtsson A, Ofori MF, Kusi KA, Koram KA, Hviid L, Adams Y, Jensen ATR.

Infect Immun. 2019 Sep 19;87(10). pii: e00224-19. doi: 10.1128/IAI.00224-19. Print 2019 Oct.


Flavonoids isolated from Tibetan medicines, binding to GABAA receptor and the anticonvulsant activity.

Liu Z, Lindemeyer AK, Liang J, Wallner M, Shao XM, Shao Y, Tao Y, Olsen RW.

Phytomedicine. 2018 Nov 15;50:1-7. doi: 10.1016/j.phymed.2018.09.198. Epub 2018 Sep 18.


Blood outgrowth endothelial cells (BOECs) as a novel tool for studying adhesion of Plasmodium falciparum-infected erythrocytes.

Ecklu-Mensah G, Olsen RW, Bengtsson A, Ofori MF, Hviid L, Jensen ATR, Adams Y.

PLoS One. 2018 Oct 9;13(10):e0204177. doi: 10.1371/journal.pone.0204177. eCollection 2018.


Single Ethanol Withdrawal Regulates Extrasynaptic δ-GABAA Receptors Via PKCδ Activation.

Chen J, He Y, Wu Y, Zhou H, Su LD, Li WN, Olsen RW, Liang J, Zhou YD, Shen Y.

Front Mol Neurosci. 2018 Apr 26;11:141. doi: 10.3389/fnmol.2018.00141. eCollection 2018.


Natural and Vaccine-Induced Acquisition of Cross-Reactive IgG-Inhibiting ICAM-1-Specific Binding of a Plasmodium falciparum PfEMP1 Subtype Associated Specifically with Cerebral Malaria.

Olsen RW, Ecklu-Mensah G, Bengtsson A, Ofori MF, Lusingu JPA, Castberg FC, Hviid L, Adams Y, Jensen ATR.

Infect Immun. 2018 Mar 22;86(4). pii: e00622-17. doi: 10.1128/IAI.00622-17. Print 2018 Apr.


GABAA receptor: Positive and negative allosteric modulators.

Olsen RW.

Neuropharmacology. 2018 Jul 1;136(Pt A):10-22. doi: 10.1016/j.neuropharm.2018.01.036. Epub 2018 Jan 31. Review.


Role of GABAA receptors in alcohol use disorders suggested by chronic intermittent ethanol (CIE) rodent model.

Olsen RW, Liang J.

Mol Brain. 2017 Sep 20;10(1):45. doi: 10.1186/s13041-017-0325-8. Review.


Decreased surface expression of the δ subunit of the GABAA receptor contributes to reduced tonic inhibition in dentate granule cells in a mouse model of fragile X syndrome.

Zhang N, Peng Z, Tong X, Lindemeyer AK, Cetina Y, Huang CS, Olsen RW, Otis TS, Houser CR.

Exp Neurol. 2017 Nov;297:168-178. doi: 10.1016/j.expneurol.2017.08.008. Epub 2017 Aug 16.


α2 Subunit-Containing GABAA Receptor Subtypes Are Upregulated and Contribute to Alcohol-Induced Functional Plasticity in the Rat Hippocampus.

Lindemeyer AK, Shen Y, Yazdani F, Shao XM, Spigelman I, Davies DL, Olsen RW, Liang J.

Mol Pharmacol. 2017 Aug;92(2):101-112. doi: 10.1124/mol.116.107797. Epub 2017 May 23.


Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria.

Lennartz F, Adams Y, Bengtsson A, Olsen RW, Turner L, Ndam NT, Ecklu-Mensah G, Moussiliou A, Ofori MF, Gamain B, Lusingu JP, Petersen JE, Wang CW, Nunes-Silva S, Jespersen JS, Lau CK, Theander TG, Lavstsen T, Hviid L, Higgins MK, Jensen AT.

Cell Host Microbe. 2017 Mar 8;21(3):403-414. doi: 10.1016/j.chom.2017.02.009.


Mapping the Binding Site of a Cross-Reactive Plasmodium falciparum PfEMP1 Monoclonal Antibody Inhibitory of ICAM-1 Binding.

Lennartz F, Bengtsson A, Olsen RW, Joergensen L, Brown A, Remy L, Man P, Forest E, Barfod LK, Adams Y, Higgins MK, Jensen AT.

J Immunol. 2015 Oct 1;195(7):3273-83. doi: 10.4049/jimmunol.1501404. Epub 2015 Aug 28.


Allosteric ligands and their binding sites define γ-aminobutyric acid (GABA) type A receptor subtypes.

Olsen RW.

Adv Pharmacol. 2015;73:167-202. doi: 10.1016/bs.apha.2014.11.005. Epub 2015 Jan 17.


Alcohol use disorders and current pharmacological therapies: the role of GABA(A) receptors.

Liang J, Olsen RW.

Acta Pharmacol Sin. 2014 Aug;35(8):981-93. doi: 10.1038/aps.2014.50. Review.


International Union of Basic and Clinical Pharmacology. XC. multisite pharmacology: recommendations for the nomenclature of receptor allosterism and allosteric ligands.

Christopoulos A, Changeux JP, Catterall WA, Fabbro D, Burris TP, Cidlowski JA, Olsen RW, Peters JA, Neubig RR, Pin JP, Sexton PM, Kenakin TP, Ehlert FJ, Spedding M, Langmead CJ.

Pharmacol Rev. 2014 Oct;66(4):918-47. doi: 10.1124/pr.114.008862.


Analysis of γ-aminobutyric acid (GABA) type A receptor subtypes using isosteric and allosteric ligands.

Olsen RW.

Neurochem Res. 2014 Oct;39(10):1924-41. doi: 10.1007/s11064-014-1382-3. Epub 2014 Jul 12.


Dihydromyricetin ameliorates behavioral deficits and reverses neuropathology of transgenic mouse models of Alzheimer's disease.

Liang J, López-Valdés HE, Martínez-Coria H, Lindemeyer AK, Shen Y, Shao XM, Olsen RW.

Neurochem Res. 2014 Jun;39(6):1171-81. doi: 10.1007/s11064-014-1304-4. Epub 2014 Apr 13. Erratum in: Neurochem Res. 2014 Jul;39(7):1403.


Selective modulation of GABAergic tonic current by dopamine in the nucleus accumbens of alcohol-dependent rats.

Liang J, Marty VN, Mulpuri Y, Olsen RW, Spigelman I.

J Neurophysiol. 2014 Jul 1;112(1):51-60. doi: 10.1152/jn.00564.2013. Epub 2014 Apr 9.


Ethanol-induced plasticity of GABAA receptors in the basolateral amygdala.

Lindemeyer AK, Liang J, Marty VN, Meyer EM, Suryanarayanan A, Olsen RW, Spigelman I.

Neurochem Res. 2014 Jun;39(6):1162-70. doi: 10.1007/s11064-014-1297-z. Epub 2014 Apr 8.


Plasticity of GABA(A) receptor-mediated neurotransmission in the nucleus accumbens of alcohol-dependent rats.

Liang J, Lindemeyer AK, Suryanarayanan A, Meyer EM, Marty VN, Ahmad SO, Shao XM, Olsen RW, Spigelman I.

J Neurophysiol. 2014 Jul 1;112(1):39-50. doi: 10.1152/jn.00565.2013. Epub 2014 Apr 2.


Dihydromyricetin prevents fetal alcohol exposure-induced behavioral and physiological deficits: the roles of GABAA receptors in adolescence.

Liang J, Shen Y, Shao XM, Scott MB, Ly E, Wong S, Nguyen A, Tan K, Kwon B, Olsen RW, Spigelman I.

Neurochem Res. 2014 Jun;39(6):1147-61. doi: 10.1007/s11064-014-1291-5. Epub 2014 Mar 28.


The role of the δ GABA(A) receptor in ovarian cycle-linked changes in hippocampus-dependent learning and memory.

Cushman JD, Moore MD, Olsen RW, Fanselow MS.

Neurochem Res. 2014 Jun;39(6):1140-6. doi: 10.1007/s11064-014-1282-6. Epub 2014 Mar 26.


Altered localization of the δ subunit of the GABAA receptor in the thalamus of α4 subunit knockout mice.

Peng Z, Zhang N, Chandra D, Homanics GE, Olsen RW, Houser CR.

Neurochem Res. 2014 Jun;39(6):1104-17. doi: 10.1007/s11064-013-1202-1. Epub 2013 Dec 19.


Structural models of ligand-gated ion channels: sites of action for anesthetics and ethanol.

Olsen RW, Li GD, Wallner M, Trudell JR, Bertaccini EJ, Lindahl E, Miller KW, Alkana RL, Davies DL.

Alcohol Clin Exp Res. 2014 Mar;38(3):595-603. doi: 10.1111/acer.12283. Epub 2013 Oct 24. Review.


Cysteine substitutions define etomidate binding and gating linkages in the α-M1 domain of γ-aminobutyric acid type A (GABAA) receptors.

Stewart DS, Hotta M, Li GD, Desai R, Chiara DC, Olsen RW, Forman SA.

J Biol Chem. 2013 Oct 18;288(42):30373-86. doi: 10.1074/jbc.M113.494583. Epub 2013 Sep 5.


Ethanol promotes clathrin adaptor-mediated endocytosis via the intracellular domain of δ-containing GABAA receptors.

Gonzalez C, Moss SJ, Olsen RW.

J Neurosci. 2012 Dec 5;32(49):17874-81. doi: 10.1523/JNEUROSCI.2535-12.2012.


A novel domain cassette identifies Plasmodium falciparum PfEMP1 proteins binding ICAM-1 and is a target of cross-reactive, adhesion-inhibitory antibodies.

Bengtsson A, Joergensen L, Rask TS, Olsen RW, Andersen MA, Turner L, Theander TG, Hviid L, Higgins MK, Craig A, Brown A, Jensen AT.

J Immunol. 2013 Jan 1;190(1):240-9. doi: 10.4049/jimmunol.1202578. Epub 2012 Dec 3.


GABAA Receptor Plasticity in Alcohol Withdrawal.

Olsen RW, Spigelman I.

In: Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, editors. Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition. Bethesda (MD): National Center for Biotechnology Information (US); 2012.


GABRB3, Epilepsy, and Neurodevelopment.

Tanaka M, DeLorey TM, Delgado-Escueta A, Olsen RW.

In: Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, editors. Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition. Bethesda (MD): National Center for Biotechnology Information (US); 2012.


Effects on promoter activity of common SNPs in 5' region of GABRB3 exon 1A.

Tanaka M, Bailey JN, Bai D, Ishikawa-Brush Y, Delgado-Escueta AV, Olsen RW.

Epilepsia. 2012 Aug;53(8):1450-6. doi: 10.1111/j.1528-1167.2012.03572.x. Epub 2012 Jul 5.


Recent advances in the discovery and preclinical testing of novel compounds for the prevention and/or treatment of alcohol use disorders.

Davies DL, Bortolato M, Finn DA, Ramaker MJ, Barak S, Ron D, Liang J, Olsen RW.

Alcohol Clin Exp Res. 2013 Jan;37(1):8-15. doi: 10.1111/j.1530-0277.2012.01846.x. Epub 2012 Jun 4. Review.


Dihydromyricetin as a novel anti-alcohol intoxication medication.

Shen Y, Lindemeyer AK, Gonzalez C, Shao XM, Spigelman I, Olsen RW, Liang J.

J Neurosci. 2012 Jan 4;32(1):390-401. doi: 10.1523/JNEUROSCI.4639-11.2012.


Subunit Compensation and Plasticity of Synaptic GABA(A) Receptors Induced by Ethanol in α4 Subunit Knockout Mice.

Suryanarayanan A, Liang J, Meyer EM, Lindemeyer AK, Chandra D, Homanics GE, Sieghart W, Olsen RW, Spigelman I.

Front Neurosci. 2011 Sep 23;5:110. doi: 10.3389/fnins.2011.00110. eCollection 2011.


Behavioral pharmacogenetic analysis on the role of the α4 GABA(A) receptor subunit in the ethanol-mediated impairment of hippocampus-dependent contextual learning.

Cushman JD, Moore MD, Jacobs NS, Olsen RW, Fanselow MS.

Alcohol Clin Exp Res. 2011 Nov;35(11):1948-59. doi: 10.1111/j.1530-0277.2011.01546.x. Epub 2011 Sep 21.


Combining Ubiquitin Deficiency and GABA-Mediated Inhibition Equals Seizures?

Olsen RW.

Epilepsy Curr. 2011 May;11(3):96-8. doi: 10.5698/1535-7511-11.3.96. No abstract available.


Deletion of astroglial Dicer causes non-cell-autonomous neuronal dysfunction and degeneration.

Tao J, Wu H, Lin Q, Wei W, Lu XH, Cantle JP, Ao Y, Olsen RW, Yang XW, Mody I, Sofroniew MV, Sun YE.

J Neurosci. 2011 Jun 1;31(22):8306-19. doi: 10.1523/JNEUROSCI.0567-11.2011.


Extrasynaptic GABAA receptors in the nucleus accumbens are necessary for alcohol drinking.

Olsen RW.

Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4699-700. doi: 10.1073/pnas.1102818108. Epub 2011 Mar 9. No abstract available.


GABA(A) receptors as molecular targets of general anesthetics: identification of binding sites provides clues to allosteric modulation.

Olsen RW, Li GD.

Can J Anaesth. 2011 Feb;58(2):206-15. doi: 10.1007/s12630-010-9429-7. Epub 2010 Dec 31. Review.


Plasticity of GABAA receptors after ethanol pre-exposure in cultured hippocampal neurons.

Shen Y, Lindemeyer AK, Spigelman I, Sieghart W, Olsen RW, Liang J.

Mol Pharmacol. 2011 Mar;79(3):432-42. doi: 10.1124/mol.110.068650. Epub 2010 Dec 16.


Identification of direct protein targets of small molecules.

Lomenick B, Olsen RW, Huang J.

ACS Chem Biol. 2011 Jan 21;6(1):34-46. doi: 10.1021/cb100294v. Epub 2010 Nov 30. Review.


p-Trifluoromethyldiazirinyl-etomidate: a potent photoreactive general anesthetic derivative of etomidate that is selective for ligand-gated cationic ion channels.

Husain SS, Stewart D, Desai R, Hamouda AK, Li SG, Kelly E, Dostalova Z, Zhou X, Cotten JF, Raines DE, Olsen RW, Cohen JB, Forman SA, Miller KW.

J Med Chem. 2010 Sep 9;53(17):6432-44. doi: 10.1021/jm100498u.


Alcohol- and alcohol antagonist-sensitive human GABAA receptors: tracking δ subunit incorporation into functional receptors.

Meera P, Olsen RW, Otis TS, Wallner M.

Mol Pharmacol. 2010 Nov;78(5):918-24. doi: 10.1124/mol.109.062687. Epub 2010 Aug 10.


Numerous classes of general anesthetics inhibit etomidate binding to gamma-aminobutyric acid type A (GABAA) receptors.

Li GD, Chiara DC, Cohen JB, Olsen RW.

J Biol Chem. 2010 Mar 19;285(12):8615-20. doi: 10.1074/jbc.M109.074708. Epub 2010 Jan 18.


Trace and contextual fear conditioning is enhanced in mice lacking the alpha4 subunit of the GABA(A) receptor.

Moore MD, Cushman J, Chandra D, Homanics GE, Olsen RW, Fanselow MS.

Neurobiol Learn Mem. 2010 Mar;93(3):383-7. doi: 10.1016/j.nlm.2009.12.004. Epub 2009 Dec 14.


Tolerance to sedative/hypnotic actions of GABAergic drugs correlates with tolerance to potentiation of extrasynaptic tonic currents of alcohol-dependent rats.

Liang J, Spigelman I, Olsen RW.

J Neurophysiol. 2009 Jul;102(1):224-33. doi: 10.1152/jn.90484.2008. Epub 2009 May 6.


Neurosteroids allosterically modulate binding of the anesthetic etomidate to gamma-aminobutyric acid type A receptors.

Li GD, Chiara DC, Cohen JB, Olsen RW.

J Biol Chem. 2009 May 1;284(18):11771-5. doi: 10.1074/jbc.C900016200. Epub 2009 Mar 12.


IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels.

Harmar AJ, Hills RA, Rosser EM, Jones M, Buneman OP, Dunbar DR, Greenhill SD, Hale VA, Sharman JL, Bonner TI, Catterall WA, Davenport AP, Delagrange P, Dollery CT, Foord SM, Gutman GA, Laudet V, Neubig RR, Ohlstein EH, Olsen RW, Peters J, Pin JP, Ruffolo RR, Searls DB, Wright MW, Spedding M.

Nucleic Acids Res. 2009 Jan;37(Database issue):D680-5. doi: 10.1093/nar/gkn728. Epub 2008 Oct 23.

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