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Items: 1 to 50 of 67

1.

Algorithmic Clustering Of Single-Cell Cytometry Data-How Unsupervised Are These Analyses Really?

Pedersen CB, Olsen LR.

Cytometry A. 2019 Nov 5. doi: 10.1002/cyto.a.23917. [Epub ahead of print] No abstract available.

PMID:
31688998
2.

RNase H-dependent PCR-enabled T-cell receptor sequencing for highly specific and efficient targeted sequencing of T-cell receptor mRNA for single-cell and repertoire analysis.

Li S, Sun J, Allesøe R, Datta K, Bao Y, Oliveira G, Forman J, Jin R, Olsen LR, Keskin DB, Shukla SA, Wu CJ, Livak KJ.

Nat Protoc. 2019 Aug;14(8):2571-2594. doi: 10.1038/s41596-019-0195-x. Epub 2019 Jul 24.

PMID:
31341290
3.

Analysis of Mass Cytometry Data.

Pedersen CB, Olsen LR.

Methods Mol Biol. 2019;1989:267-279. doi: 10.1007/978-1-4939-9454-0_17.

PMID:
31077111
4.

Getting the Most from Your High-Dimensional Cytometry Data.

Olsen LR, Pedersen CB, Leipold MD, Maecker HT.

Immunity. 2019 Mar 19;50(3):535-536. doi: 10.1016/j.immuni.2019.02.015. No abstract available.

PMID:
30893579
5.

Publisher Correction: Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses.

Napolitani G, Kurupati P, Teng KWW, Gibani MM, Rei M, Aulicino A, Preciado-Llanes L, Wong MT, Becht E, Howson L, de Haas P, Salio M, Blohmke CJ, Olsen LR, Pinto DMS, Scifo L, Jones C, Dobinson H, Campbell D, Juel HB, Thomaides-Brears H, Pickard D, Bumann D, Baker S, Dougan G, Simmons A, Gordon MA, Newell EW, Pollard AJ, Cerundolo V.

Nat Immunol. 2019 Apr;20(4):514. doi: 10.1038/s41590-019-0357-6.

PMID:
30862955
6.

Pregnancy outcomes after recurrent pregnancy loss: a longitudinal cohort study on stress and depression.

Kolte AM, Olsen LR, Christiansen OB, Schmidt L, Nielsen HS.

Reprod Biomed Online. 2019 Apr;38(4):599-605. doi: 10.1016/j.rbmo.2018.12.006. Epub 2018 Dec 20.

PMID:
30819570
7.

BioReader: a text mining tool for performing classification of biomedical literature.

Simon C, Davidsen K, Hansen C, Seymour E, Barnkob MB, Olsen LR.

BMC Bioinformatics. 2019 Feb 4;19(Suppl 13):57. doi: 10.1186/s12859-019-2607-x.

8.

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial.

Keskin DB, Anandappa AJ, Sun J, Tirosh I, Mathewson ND, Li S, Oliveira G, Giobbie-Hurder A, Felt K, Gjini E, Shukla SA, Hu Z, Li L, Le PM, Allesøe RL, Richman AR, Kowalczyk MS, Abdelrahman S, Geduldig JE, Charbonneau S, Pelton K, Iorgulescu JB, Elagina L, Zhang W, Olive O, McCluskey C, Olsen LR, Stevens J, Lane WJ, Salazar AM, Daley H, Wen PY, Chiocca EA, Harden M, Lennon NJ, Gabriel S, Getz G, Lander ES, Regev A, Ritz J, Neuberg D, Rodig SJ, Ligon KL, Suvà ML, Wucherpfennig KW, Hacohen N, Fritsch EF, Livak KJ, Ott PA, Wu CJ, Reardon DA.

Nature. 2019 Jan;565(7738):234-239. doi: 10.1038/s41586-018-0792-9. Epub 2018 Dec 19.

9.

Computational Methods for Identification of T Cell Neoepitopes in Tumors.

Jurtz VI, Olsen LR.

Methods Mol Biol. 2019;1878:157-172. doi: 10.1007/978-1-4939-8868-6_9.

PMID:
30378075
10.

Using microarray-based subtyping methods for breast cancer in the era of high-throughput RNA sequencing.

Pedersen CB, Nielsen FC, Rossing M, Olsen LR.

Mol Oncol. 2018 Dec;12(12):2136-2146. doi: 10.1002/1878-0261.12389. Epub 2018 Oct 29.

11.

The anatomy of single cell mass cytometry data.

Olsen LR, Leipold MD, Pedersen CB, Maecker HT.

Cytometry A. 2019 Feb;95(2):156-172. doi: 10.1002/cyto.a.23621. Epub 2018 Oct 2. Review.

PMID:
30277658
12.

Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses.

Napolitani G, Kurupati P, Teng KWW, Gibani MM, Rei M, Aulicino A, Preciado-Llanes L, Wong MT, Becht E, Howson L, de Haas P, Salio M, Blohmke CJ, Olsen LR, Pinto DMS, Scifo L, Jones C, Dobinson H, Campbell D, Juel HB, Thomaides-Brears H, Pickard D, Bumann D, Baker S, Dougan G, Simmons A, Gordon MA, Newell EW, Pollard AJ, Cerundolo V.

Nat Immunol. 2018 Jul;19(7):742-754. doi: 10.1038/s41590-018-0133-z. Epub 2018 Jun 20. Erratum in: Nat Immunol. 2019 Apr;20(4):514.

PMID:
29925993
13.

Molecular profiling of short-term and long-term surviving patients identifies CD34 mRNA level as prognostic for glioblastoma survival.

Michaelsen SR, Urup T, Olsen LR, Broholm H, Lassen U, Poulsen HS.

J Neurooncol. 2018 May;137(3):533-542. doi: 10.1007/s11060-017-2739-7. Epub 2018 Jan 5.

PMID:
29305787
14.

Comparison of CyTOF assays across sites: Results of a six-center pilot study.

Leipold MD, Obermoser G, Fenwick C, Kleinstuber K, Rashidi N, McNevin JP, Nau AN, Wagar LE, Rozot V, Davis MM, DeRosa S, Pantaleo G, Scriba TJ, Walker BD, Olsen LR, Maecker HT.

J Immunol Methods. 2018 Feb;453:37-43. doi: 10.1016/j.jim.2017.11.008. Epub 2017 Nov 23.

15.

Transcriptional changes induced by bevacizumab combination therapy in responding and non-responding recurrent glioblastoma patients.

Urup T, Staunstrup LM, Michaelsen SR, Vitting-Seerup K, Bennedbæk M, Toft A, Olsen LR, Jønson L, Issazadeh-Navikas S, Broholm H, Hamerlik P, Poulsen HS, Lassen U.

BMC Cancer. 2017 Apr 18;17(1):278. doi: 10.1186/s12885-017-3251-3.

16.

Danish translation and validation of Kessler's 10-item psychological distress scale - K10.

Thelin C, Mikkelsen B, Laier G, Turgut L, Henriksen B, Olsen LR, Larsen JK, Arnfred S.

Nord J Psychiatry. 2017 Aug;71(6):411-416. doi: 10.1080/08039488.2017.1312517. Epub 2017 Apr 18.

PMID:
28417648
17.

TANTIGEN: a comprehensive database of tumor T cell antigens.

Olsen LR, Tongchusak S, Lin H, Reinherz EL, Brusic V, Zhang GL.

Cancer Immunol Immunother. 2017 Jun;66(6):731-735. doi: 10.1007/s00262-017-1978-y. Epub 2017 Mar 9.

PMID:
28280852
18.

Nutritional Stress Induced by Tryptophan-Degrading Enzymes Results in ATF4-Dependent Reprogramming of the Amino Acid Transporter Profile in Tumor Cells.

Timosenko E, Ghadbane H, Silk JD, Shepherd D, Gileadi U, Howson LJ, Laynes R, Zhao Q, Strausberg RL, Olsen LR, Taylor S, Buffa FM, Boyd R, Cerundolo V.

Cancer Res. 2016 Nov 1;76(21):6193-6204. Epub 2016 Sep 20.

19.

Angiotensinogen and HLA class II predict bevacizumab response in recurrent glioblastoma patients.

Urup T, Michaelsen SR, Olsen LR, Toft A, Christensen IJ, Grunnet K, Winther O, Broholm H, Kosteljanetz M, Issazadeh-Navikas S, Poulsen HS, Lassen U.

Mol Oncol. 2016 Oct;10(8):1160-8. doi: 10.1016/j.molonc.2016.05.005. Epub 2016 May 26.

20.

A clinimetric analysis of the Hopkins Symptom Checklist (SCL-90-R) in general population studies (Denmark, Norway, and Italy).

Carrozzino D, Vassend O, Bjørndal F, Pignolo C, Olsen LR, Bech P.

Nord J Psychiatry. 2016 Jul;70(5):374-9. doi: 10.3109/08039488.2016.1155235. Epub 2016 Apr 6.

PMID:
27049691
21.

A comprehensive profile of recurrent glioblastoma.

Campos B, Olsen LR, Urup T, Poulsen HS.

Oncogene. 2016 Nov 10;35(45):5819-5825. doi: 10.1038/onc.2016.85. Epub 2016 Apr 4. Review.

PMID:
27041580
22.

A computational method for identification of vaccine targets from protein regions of conserved human leukocyte antigen binding.

Olsen LR, Simon C, Kudahl UJ, Bagger FO, Winther O, Reinherz EL, Zhang GL, Brusic V.

BMC Med Genomics. 2015;8 Suppl 4:S1. doi: 10.1186/1755-8794-8-S4-S1. Epub 2015 Dec 9.

23.

FluKB: A Knowledge-Based System for Influenza Vaccine Target Discovery and Analysis of the Immunological Properties of Influenza Viruses.

Simon C, Kudahl UJ, Sun J, Olsen LR, Zhang GL, Reinherz EL, Brusic V.

J Immunol Res. 2015;2015:380975. doi: 10.1155/2015/380975. Epub 2015 Oct 4.

24.

Characterization of midazolam metabolism in locusts: the role of a CYP3A4-like enzyme in the formation of 1'-OH and 4-OH midazolam.

Olsen LR, Gabel-Jensen C, Wubshet SG, Kongstad KT, Janfelt C, Badolo L, Hansen SH.

Xenobiotica. 2016;46(2):99-107. doi: 10.3109/00498254.2015.1051604. Epub 2015 Jul 24.

PMID:
26207435
25.

Cross-cultural adaptation and validation of the Danish consensus version of the 10-item Perceived Stress Scale.

Eskildsen A, Dalgaard VL, Nielsen KJ, Andersen JH, Zachariae R, Olsen LR, Jørgensen A, Christiansen DH.

Scand J Work Environ Health. 2015 Sep 1;41(5):486-90. doi: 10.5271/sjweh.3510. Epub 2015 Jun 25.

26.

Comparison of mental distress in patients with low back pain and a population-based control group measured by Symptoms Check List--A case-referent study.

Christensen J, Fisker A, Mortensen EL, Olsen LR, Mortensen OS, Hartvigsen J, Langberg H.

Scand J Public Health. 2015 Aug;43(6):638-47. doi: 10.1177/1403494815581697. Epub 2015 May 11.

PMID:
25964126
27.

Depression and emotional stress is highly prevalent among women with recurrent pregnancy loss.

Kolte AM, Olsen LR, Mikkelsen EM, Christiansen OB, Nielsen HS.

Hum Reprod. 2015 Apr;30(4):777-82. doi: 10.1093/humrep/dev014. Epub 2015 Feb 5.

28.

Characterization of a novel brain barrier ex vivo insect-based P-glycoprotein screening model.

Andersson O, Badisco L, Hansen AH, Hansen SH, Hellman K, Nielsen PA, Olsen LR, Verdonck R, Abbott NJ, Vanden Broeck J, Andersson G.

Pharmacol Res Perspect. 2014 Aug;2(4):e00050. doi: 10.1002/prp2.50. Epub 2014 Jun 9.

29.

Distribution of terfenadine and its metabolites in locusts studied by desorption electrospray ionization mass spectrometry imaging.

Olsen LR, Hansen SH, Janfelt C.

Anal Bioanal Chem. 2015 Mar;407(8):2149-58. doi: 10.1007/s00216-014-8292-8. Epub 2014 Nov 18.

PMID:
25404166
30.

Bioinformatics for cancer immunotherapy target discovery.

Olsen LR, Campos B, Barnkob MS, Winther O, Brusic V, Andersen MH.

Cancer Immunol Immunother. 2014 Dec;63(12):1235-49. doi: 10.1007/s00262-014-1627-7. Epub 2014 Oct 26. Review.

PMID:
25344903
31.

Characterizing the human hematopoietic CDome.

Barnkob MS, Simon C, Olsen LR.

Front Genet. 2014 Sep 25;5:331. doi: 10.3389/fgene.2014.00331. eCollection 2014.

32.

Software-supported USER cloning strategies for site-directed mutagenesis and DNA assembly.

Genee HJ, Bonde MT, Bagger FO, Jespersen JB, Sommer MO, Wernersson R, Olsen LR.

ACS Synth Biol. 2015 Mar 20;4(3):342-9. doi: 10.1021/sb500194z. Epub 2014 May 21.

PMID:
24847672
33.

Identification of a functional homolog of the mammalian CYP3A4 in locusts.

Olsen LR, Gabel-Jensen C, Nielsen PA, Hansen SH, Badolo L.

Drug Metab Dispos. 2014 Jul;42(7):1153-62. doi: 10.1124/dmd.114.057430. Epub 2014 Apr 28.

PMID:
24778367
34.

BlockLogo: visualization of peptide and sequence motif conservation.

Olsen LR, Kudahl UJ, Simon C, Sun J, Schönbach C, Reinherz EL, Zhang GL, Brusic V.

J Immunol Methods. 2013 Dec 31;400-401:37-44. doi: 10.1016/j.jim.2013.08.014. Epub 2013 Aug 31.

35.

The grasshopper: a novel model for assessing vertebrate brain uptake.

Andersson O, Hansen SH, Hellman K, Olsen LR, Andersson G, Badolo L, Svenstrup N, Nielsen PA.

J Pharmacol Exp Ther. 2013 Aug;346(2):211-8. doi: 10.1124/jpet.113.205476. Epub 2013 May 13.

PMID:
23671124
36.

Health consumption in Sami speaking municipalities and a control group with regard to medical imaging.

Størmer J, Norum J, Olsen LR, Eldevik P, Broderstad AR.

Int J Circumpolar Health. 2012 Mar 23;71:17620. doi: 10.3402/ijch.v71i0.17620.

37.

PHUSER (Primer Help for USER): a novel tool for USER fusion primer design.

Olsen LR, Hansen NB, Bonde MT, Genee HJ, Holm DK, Carlsen S, Hansen BG, Patil KR, Mortensen UH, Wernersson R.

Nucleic Acids Res. 2011 Jul;39(Web Server issue):W61-7. doi: 10.1093/nar/gkr394. Epub 2011 May 26.

38.

Constituents in kava extracts potentially involved in hepatotoxicity: a review.

Olsen LR, Grillo MP, Skonberg C.

Chem Res Toxicol. 2011 Jul 18;24(7):992-1002. doi: 10.1021/tx100412m. Epub 2011 May 3. Review.

PMID:
21506562
39.

Methodological challenges in hip fracture registration: the Harstad Injury Registry.

Emaus N, Heiberg I, Ahmed LA, Balteskard L, Jacobsen BK, Magnus T, Olsen LR, Ytterstad B.

Int J Inj Contr Saf Promot. 2011 Jun;18(2):135-42. doi: 10.1080/17457300.2010.540331.

PMID:
21432705
40.

Hip fractures in a city in Northern Norway over 15 years: time trends, seasonal variation and mortality : the Harstad Injury Prevention Study.

Emaus N, Olsen LR, Ahmed LA, Balteskard L, Jacobsen BK, Magnus T, Ytterstad B.

Osteoporos Int. 2011 Oct;22(10):2603-10. doi: 10.1007/s00198-010-1485-x. Epub 2011 Jan 20.

41.
42.

Conservation analysis of dengue virus T-cell epitope-based vaccine candidates using Peptide block entropy.

Olsen LR, Zhang GL, Keskin DB, Reinherz EL, Brusic V.

Front Immunol. 2011 Dec 20;2:69. doi: 10.3389/fimmu.2011.00069. eCollection 2011.

43.

Preferential inhibition of the mRNA expression of p38 mitogen-activated protein kinase regulated cytokines in psoriatic skin by anti-TNFα therapy.

Johansen C, Vinter H, Soegaard-Madsen L, Olsen LR, Steiniche T, Iversen L, Kragballe K.

Br J Dermatol. 2010 Dec;163(6):1194-204. doi: 10.1111/j.1365-2133.2010.10036.x.

PMID:
20846304
44.

Occupational position and its relation to mental distress in a random sample of Danish residents.

Rugulies R, Madsen IE, Nielsen MB, Olsen LR, Mortensen EL, Bech P.

Int Arch Occup Environ Health. 2010 Aug;83(6):625-9. doi: 10.1007/s00420-009-0492-8. Epub 2009 Dec 1.

PMID:
19949958
45.

[The prevalence of depression in Denmark].

Olsen LR, Munk-Jørgensen P, Bech P.

Ugeskr Laeger. 2007 Apr 16;169(16):1425-6. Danish.

PMID:
17484835
46.

Structure of the E. coli bifunctional GlmU acetyltransferase active site with substrates and products.

Olsen LR, Vetting MW, Roderick SL.

Protein Sci. 2007 Jun;16(6):1230-5. Epub 2007 May 1.

47.

Mental distress in the Danish general population.

Olsen LR, Mortensen EL, Bech P.

Acta Psychiatr Scand. 2006 Jun;113(6):477-84.

PMID:
16677224
48.

[Street prostitution and drug addiction].

Ishøy T, Ishøy PL, Olsen LR.

Ugeskr Laeger. 2005 Sep 26;167(39):3692-6. Danish.

PMID:
16219218
50.

The SCL-90 and SCL-90R versions validated by item response models in a Danish community sample.

Olsen LR, Mortensen EL, Bech P.

Acta Psychiatr Scand. 2004 Sep;110(3):225-9.

PMID:
15283743

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